Doppler haemodynamics of cerebral venous return.

Abstract:

:Physiologic functioning of the cerebrovenous system is indispensable for maintaining normal brain function. However, in contrast to the cerebroarterial system, the cerebral venous return is not routinely investigated. Combined high-resolution echo-colour-Doppler (ECD) and transcranial colour coded Doppler sonography (TCCS) represents an ideal method to investigate the haemodynamics of cerebral venous return. TCCS-ECD is noninvasive, repeatable, cost-effective and permits to investigate the cerebral venous outflow in its dependence upon changes in posture and the alternating pressure gradients of the thoracic pump. Several authors reported normal parameters concerning related aspects of cerebral venous return. However, there is no ECD-TCCS standardization of what can be considered a normal venous return. The authors have summarized the current knowledge of the Doppler haemodynamics of the cerebrovenous system and propose a list of reproducible clinical parameters for its sonographic evaluation. In future, the development of this diagnostic technique could be of singular interest in iron-related inflammatory and neurodegenerative disorders like multiple sclerosis.

journal_name

Curr Neurovasc Res

authors

Menegatti E,Zamboni P

doi

10.2174/156720208786413442

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

260-5

issue

4

eissn

1567-2026

issn

1875-5739

journal_volume

5

pub_type

杂志文章,评审
  • Adrenergic modulation of dendritic cells function: relevance for the immune homeostasis.

    abstract::Dendritic cells (DC) play a key role in determining the appropriate immune response to invading pathogens and tolerance to self antigens. Here I review the evidence that dendritic cell functions may be tuned by the sympathetic nervous system via the local release of norepinephrine. In the presence of antigens or micro...

    journal_title:Current neurovascular research

    pub_type: 杂志文章,评审

    doi:10.2174/1567202053586776

    authors: Maestroni GJ

    更新日期:2005-04-01 00:00:00

  • Human mesenchymal stem cells increases expression of α-tubulin and angiopoietin 1 and 2 in focal cerebral ischemia and reperfusion.

    abstract::Angiogenesis is associated with improved neurologic recovery after cerebral ischemia. Human bone marrow mesenchymal stem cells (hMSCs) have been successfully used to treat ischemic stroke and were shown to induce the expression of a number of neurotrophic factors including VEGF, epidermal growth factor (EGF) and basic...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202611310020003

    authors: Ma XL,Liu KD,Li FC,Jiang XM,Jiang L,Li HL

    更新日期:2013-05-01 00:00:00

  • Nifedipine inhibits the progression of an experimentally induced cerebral aneurysm in rats with associated down-regulation of NF-kappa B transcriptional activity.

    abstract::Cerebral aneurysm (CA) causes a life-threatening subarachnoid hemorrhage. However, no effective medical treatment to prevent the growth of CA is available. Nifedipine, a widely used calcium antagonist, was shown to improve endothelial function in various cardiovascular diseases. We examined whether nifedipine has a pr...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/156720208783565663

    authors: Aoki T,Kataoka H,Ishibashi R,Nozaki K,Hashimoto N

    更新日期:2008-02-01 00:00:00

  • Using endogenous neural stem cells to enhance recovery from ischemic brain injury.

    abstract::The use of cell-based therapy may be a valid therapeutic approach to ischemic brain injury. Stem cells have been proposed as a new form of cell based therapy in a variety of disorders, including acute and degenerative brain diseases. Up to date most efforts have concentrated on transplantation of embryonic stem cells ...

    journal_title:Current neurovascular research

    pub_type: 杂志文章,评审

    doi:10.2174/1567202043361938

    authors: Leker RR,McKay RD

    更新日期:2004-12-01 00:00:00

  • NF-κB Inhibition Resolves Cognitive Deficits in Experimental Type 2 Diabetes Mellitus through CREB and Glutamate/GABA Neurotransmitters Pathway.

    abstract::Diabetes is associated with deficits in memory and cognitive functions and sustained inflammation. Recently, involvement of NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) has been postulated in many cognitive functions, immune system and inflammation. Despite of role of NF-κB in inflammation, a...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202612666151030104810

    authors: Datusalia AK,Sharma SS

    更新日期:2016-01-01 00:00:00

  • NRF2-dependent glutamate-L-cysteine ligase catalytic subunit expression mediates insulin protection against hyperglycemia- induced brain endothelial cell apoptosis.

    abstract::Increased oxidative stress and susceptibility of brain endothelium are contributing factors in the development of central nervous system complications in neuro-degenerative disorders in diabetes, Alzheimer's and Parkinson's disease. The molecular mechanisms underpinning the vulnerability of brain endothelial cells to ...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/156720206778792876

    authors: Okouchi M,Okayama N,Alexander JS,Aw TY

    更新日期:2006-11-01 00:00:00

  • Platelet-derived Growth Factor Receptor-beta is Differentially Regulated in Primary Mouse Pericytes and Brain Slices.

    abstract::Pericytes are perivascular cells and have heterogenous roles in the brain, such as controlling blood flow and entry of immune cells or regulating the blood-brain barrier. Platelet-derived growth factor (PDGF) receptor-beta (PDGFRβ) is highly expressed in pericytes, representing the most selective biomarker. The aim of...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202613666160219120411

    authors: Hutter-Schmid B,Humpel C

    更新日期:2016-01-01 00:00:00

  • An experimental model for exudative age-related macular degeneration with choroidal neovascularization using the common marmoset.

    abstract::This study aimed to establish an experimental exudative age-related macular degeneration (AMD) model in the common marmoset (Callithrix jacchus), which is a small New World monkey. Choroidal neovascularization (CNV) was induced by laser irradiation on the left eye of each animal under anesthesia. Eight laser spots wer...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202612666150311105814

    authors: Shimazawa M,Masuda T,Nakamura S,Miwa M,Nakamura K,Hara H

    更新日期:2015-01-01 00:00:00

  • Neurohormonal activation in ischemic stroke: effects of acute phase disturbances on long-term mortality.

    abstract::A stress response consisting of elevated levels of cortisol and catecholamines is common after acute stroke. The plasma levels of natriuretic peptides are known to be elevated after ischemic stroke, but the relations of these neurohormonal systems in the acute phase of stroke and their impact on long-term prognosis ha...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/156720207781387169

    authors: Anne M,Juha K,Timo M,Mikko T,Olli V,Kyösti S,Heikki H,Vilho M

    更新日期:2007-08-01 00:00:00

  • Higher Levels of Dynamin-related Protein 1 are Associated with Reduced Radiation Sensitivity of Glioblastoma Cells.

    abstract:BACKGROUND:Dynamin-related protein 1 (DRP1) is a GTPase involved in mitochondrial fission, mitochondrial protein import, and drug sensitivity, suggesting an association with cancer progression. This study was conducted to evaluate the prognostic significance of DRP1 in glioblastoma multiforme (GBM). METHODS:DRP1 expre...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202617666200623123638

    authors: Cheng WY,Chow KC,Chiao MT,Yang YC,Shen CC

    更新日期:2020-01-01 00:00:00

  • Prolactin and blood-brain barrier permeability.

    abstract::The blood-brain barrier (BBB) consists in part of a highly specialized set of cells which separates the brain from the vascular system. The BBB controls the entry and exit of substances from the brain tissue through tight junctions (TJs) between endothelial cells. It is known that the hormone prolactin (PRL) is able t...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/15672026113109990025

    authors: Rosas-Hernandez H,Cuevas E,Lantz SM,Hamilton WR,Ramirez-Lee MA,Ali SF,Gonzalez C

    更新日期:2013-11-01 00:00:00

  • Dexmedetomidine Pretreatment Improves Lipopolysaccharide-induced Iron Homeostasis Disorder in Aged Mice.

    abstract:BACKGROUND:Iron homeostasis disorder and neuroinflammation are the most commonly known factors that promote the occurrence and development of cognitive impairment in people. Dexmedetomidine has an anti-inflammatory effect, and it reduces the incidence of postoperative cognitive dysfunction. Therefore, the aim of this s...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202617666200217105109

    authors: Guo F,Kang J,Tan J,Wang Y,Jia L,Xu H

    更新日期:2020-01-01 00:00:00

  • Centralized and Local Color Doppler Ultrasound Reading Agreement for Diagnosis of the Chronic Cerebrospinal Venous Insufficiency in Patients with Multiple Sclerosis.

    abstract:BACKGROUND:An impaired cerebrospinal venous drainage was postulated to be a cofactor in the multifactorial pathogenesis of multiple sclerosis (MS). Chronic cerebrospinal venous insufficiency (CCSVI) is characterized by abnormalities of the main extracranial cerebrospinal venous outflow routes, which can be detected by ...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202614666170718095203

    authors: Caprio MG,Marr K,Gandhi S,Jakimovski D,Hagemeier J,Weinstock-Guttman B,Zivadinov R,Mancini M

    更新日期:2017-01-01 00:00:00

  • Recombinant human growth hormone in abstinent androgenic-anabolic steroid use: psychological, endocrine and trophic factor effects.

    abstract::This study examined whether six days recombinant human growth hormone (rhGH) affected psychological profile in an abstinent androgenic-anabolic steroid (AAS) abusing group, compared with an abstinent AAS control group. Male subjects (n = 48) were assigned in a random fashion into one of two groups: (1): (n=24) control...

    journal_title:Current neurovascular research

    pub_type: 杂志文章,随机对照试验

    doi:10.2174/156720207779940699

    authors: Graham MR,Davies B,Kicman A,Cowan D,Hullin D,Baker JS

    更新日期:2007-02-01 00:00:00

  • Hypoxia-inducible factor-1α contributes to brain edema after stroke by regulating aquaporins and glycerol distribution in brain.

    abstract::Brain edema following stroke is a critical clinical problem due to its association with increased morbidity and mortality. Despite its significance, present treatment for brain edema simply provides symptomatic relief due to the fact that molecular mechanisms underlying brain edema remain poorly understood. The presen...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/156720211794520251

    authors: Higashida T,Peng C,Li J,Dornbos D 3rd,Teng K,Li X,Kinni H,Guthikonda M,Ding Y

    更新日期:2011-02-01 00:00:00

  • Necessity for re-vascularization after spinal cord injury and the search for potential therapeutic options.

    abstract::Disruption of the blood-spinal cord barrier (BSCB) and microvascular changes leading to reduction of blood supply represent hallmarks of spinal cord secondary injury causing further deterioration of the traumatized patient. Injury to the blood vessels starts with prominent hemorrhage and generation of inflammation. Fu...

    journal_title:Current neurovascular research

    pub_type: 杂志文章,评审

    doi:10.2174/156720211798121007

    authors: Graumann U,Ritz MF,Hausmann O

    更新日期:2011-11-01 00:00:00

  • TRPA1 and TRPM8 Receptors May Promote Local Vasodilation that Aggravates Oxaliplatin-Induced Peripheral Neuropathy Amenable to 17β-Estradiol Treatment.

    abstract::Oxaliplatin is a widely used chemotherapeutic agent that induces both acute and chronic peripheral neuropathy. Based on previous research indicating that estrogen replacement may attenuate some forms of pain in ovariectomized animals, we examined the effects of 17β-estradiol in OXAIPN. We discovered that local cold ex...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202613666160601144254

    authors: Pan Y,Chen F,Huang S,Cai Z,Lan H,Tong Y,Yu X,Zhao G

    更新日期:2016-01-01 00:00:00

  • Improved Outcomes after Reperfusion Therapies for Ischemic Stroke: A "Real-world" Study in a Developing Country.

    abstract:BACKGROUND:It is unknown if improvements in ischemic stroke (IS) outcomes reported after cerebral reperfusion therapies (CRT) in developed countries are also applicable to the "real world" scenario of low and middle-income countries. We aimed to measure the long-term outcomes of severe IS treated or not with CRT in Bra...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202617666200521083132

    authors: Schulz VC,de Magalhaes PSC,Carneiro CC,da Silva JIT,Silva VN,Guesser VV,Safanelli J,Diegoli H,Liberato RB,Lopes CCC,de Souza A,de França PHC,Conforto AB,Cabral NL

    更新日期:2020-01-01 00:00:00

  • Remote Ischemic Conditioning Improves Cognitive Function During Cerebral Vascular Injury Through the Induction of Autophagy.

    abstract:BACKGROUND:The most valid model for vascular cognitive impairment (VCI) is the mouse bilateral common carotid artery stenosis (BCAS), whose behavioral outcomes are supposedly affected by the remote ischemic conditioning (RIC) through the induction of autophgy. We hope to determine whether RIC contributes to the neuropr...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202614666170619081419

    authors: Wang H,Zhang Q,Xu Y,Bian H,Si C,Yan Z,Zhu M

    更新日期:2017-01-01 00:00:00

  • Homocysteine enhances transmigration of rat monocytes through a brain capillary endothelial cell monolayer via ICAM-1.

    abstract::Increased homocysteine (Hcy) levels contribute to a variety of cardiovascular and cerebrovascular diseases including stroke and Alzheimer's disease. Recent data has shown that elevated levels of Hcy can lead to the blood-brain barrier (BBB) dysfunction and activation. However, the mechanism for Hcy-mediated dysfunctio...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/156720210792231787

    authors: Hohsfield LA,Humpel C

    更新日期:2010-08-01 00:00:00

  • Basilar Apex Aneurysms in the Setting of Carotid Artery Stenosis: Case Series and Angiographic Anatomic Study.

    abstract:BACKGROUND:Intracranial aneurysms (IAs) are life-threatening lesions known within the literature to be found incidentally during routine angiographic workup for carotid artery stenosis (CAS). As IAs are associated with vascular shear stress, it is reasonable to expect that altered flow demands within the anterior circu...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202616666190129150403

    authors: Rosenbaum MD,Heiferman DM,Raslan OA,Martin B,Dominguez JF,de la Peña PM,Ashley WW,Rosenblum JD,Germanwala AV

    更新日期:2019-01-01 00:00:00

  • Chronic hypoxia potentiates age-related oxidative imbalance in brain vessels and synaptosomes.

    abstract::This study was aimed to evaluate and compare the effect of chronic hypoxia and aging in the oxidative status of brain vessels and synaptosomes. For this purpose we isolated brain vessels and synaptosomes from 3- and 12-month-old rats subjected to chronic hypoxia (10% O₂ for 7 days) or normoxia (21% O₂). Several parame...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/156720210793180765

    authors: Carvalho C,Santos MS,Baldeiras I,Oliveira CR,Seiça R,Moreira PI

    更新日期:2010-11-01 00:00:00

  • Identification of target antigens of antiendothelial cell antibodies against human brain microvascular endothelial cells in healthy subjects.

    abstract::Antiendothelial cell antibodies (AECAs) have been detected in patients who have autoimmune and inflammatory diseases. Previous studies showed that AECAs against human umbilical vein endothelial cells were detected in healthy subjects. In the present study, we evaluated AECAs against human brain microvascular endotheli...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202612666150107161847

    authors: Kimura A,Sakurai T,Yoshikura N,Koumura A,Hayashi Y,Ohtaki H,Chousa M,Seishima M,Inuzuka T

    更新日期:2015-01-01 00:00:00

  • HspB5/alphaB-crystallin: properties and current progress in neuropathy.

    abstract::HspB5/alphaB-crystallin (alphaBC), one of the most representative member of mammalian small heat shock protein family (sHsp), shares the common features with other nine members HspB1-B4 and HspB6-10. Meanwhile, it has a strong antiapoptic effect; its interaction with cytoskeleton participates in maintaining cell struc...

    journal_title:Current neurovascular research

    pub_type: 杂志文章,评审

    doi:10.2174/156720208784310222

    authors: Hu Z,Li T

    更新日期:2008-05-01 00:00:00

  • The sirtuin inhibitor nicotinamide enhances neuronal cell survival during acute anoxic injury through AKT, BAD, PARP, and mitochondrial associated "anti-apoptotic" pathways.

    abstract::Understanding the role of nicotinamide (NIC) in different cell systems represents a significant challenge in several respects. Recently, NIC has been reported to have diverse roles during cell biology. In the absence of NIC, sirtuin protein activity is enhanced and pyrazinamidase/nicotinamidase 1 (PNC1) expression, an...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/156720205774322584

    authors: Chong ZZ,Lin SH,Li F,Maiese K

    更新日期:2005-10-01 00:00:00

  • Membrane insertion of new AMPA receptors and LTP induced by glycine is prevented by blocking NR2A-containing NMDA receptors in the rat visual cortex in vitro.

    abstract::N-methyl-D-aspartate receptors (NMDA-Rs) activation has been implicated in various forms of synaptic plasticity depending on the receptor subtypes involved. However, the contribution of NR2A and NR2B subunits in glycine-induced long-term potentiation (LTP) of miniature excitatory postsynaptic currents (mEPSCs) in laye...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/156720213804805927

    authors: Li YH,Wang J

    更新日期:2013-02-01 00:00:00

  • Selective 5-HT7 Receptor Activation May Enhance Synaptic Plasticity Through N-methyl-D-aspartate (NMDA) Receptor Activity in the Visual Cortex.

    abstract::Serotonin (5-hydroxytryptamine, 5-HT) is an important neurotransmitter that modulates N-methyl-D-aspartate (NMDA) receptor activity by binding to several different 5-HT receptor subtypes. In the present study, we used whole-cell patch-clamp recordings in transverse slice preparations to test the role of 5-HT receptors...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202613666160823164136

    authors: Xiang K,Zhao X,Li Y,Zheng L,Wang J,Li YH

    更新日期:2016-01-01 00:00:00

  • Potential Biomarkers with Plasma Cortisol, Brain-derived Neurotrophic Factor and Nitrites in Patients with Acute Ischemic Stroke.

    abstract:BACKGROUND:Acute Ischemic Stroke (AIS) represents an economic challenge for health systems all over the globe. Changes of neuroactive steroids have been found in different neurological diseases. We have previously demonstrated that old patients with AIS show changes of plasma cortisol and estradiol concentrations, in t...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202614666171005122925

    authors: Casas S,Perez AF,Mattiazzi M,Lopez J,Folgueira A,Gargiulo-Monachelli GM,Gonzalez Deniselle MC,De Nicola AF

    更新日期:2017-01-01 00:00:00

  • Biological Function and Mechanism of Bone Marrow Mesenchymal Stem Cells-packed Poly (3,4-ethylenedioxythiophene) (PEDOT) Scaffolds for Peripheral Nerve Injury: The Involvement of miR-21-Notch Signaling Pathway.

    abstract::Ununited peripheral nerves represent attractive site for connectivity with neuroprostheses because their predictable internal topography allows precise sorting of motor and sensory signals. Also transplantation of bone marrow mesenchymal stem cells (BMSCs) is increasingly recognized as an effective method of restore t...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202614666161123112832

    authors: Wu W,Zhang S,Chen Y,Liu H

    更新日期:2017-01-01 00:00:00

  • A variant in the endoglin gene is associated with the development of sporadic intracranial aneurysms.

    abstract::Intracranial aneurysms (IAs) are acquired lesions in the brain and can pose potential risk of rupture leading to subarachnoid hemorrhage. Endoglin plays a pivotal role in the vascular development and disease. Variations of endoglin gene have been shown to be risk factors for IAs in different racial population. In the ...

    journal_title:Current neurovascular research

    pub_type: 杂志文章

    doi:10.2174/1567202611666140912114450

    authors: Lin Y,Yu H,Song W,Zhang Y,Zhang C,Zhu Y,Pang Q,Hui R,Chen J

    更新日期:2014-01-01 00:00:00