Expression of CXCL12 and CXCR4 in pT3-stage gastric cancer does not correlate with peritoneal metastasis.

abstract：:Bmi-1, a member of the polycomb family, it is involved in self renewal of stem cells and functions as an oncogene in many malignant human cancer types. Recent studies have demonstrated that Bmi-1 is a predictive factor for poor patient prognosis. However, the underlying mechanisms o...

journal_title：Oncology reports

authors： Liu ZG,Liu L,Xu LH,Yi W,Tao YL,Tu ZW,Li MZ,Zeng MS,Xia YF

更新日期：2012-04-01 00:00:00

abstract：:Cancer research is currently focused on blocking the metastatic process at its early steps. Some particularly attractive targets are metastasis suppressor genes, which control cancer cell dissemination. The aim of this study was to clarify the relationship between the expression of KiSS1, a metastasis suppressor gene,...

journal_title：Oncology reports

authors： Okugawa Y,Inoue Y,Tanaka K,Toiyama Y,Shimura T,Okigami M,Kawamoto A,Hiro J,Saigusa S,Mohri Y,Uchida K,Kusunoki M

更新日期：2013-09-01 00:00:00

abstract：:Zinc finger protein 703 (ZNF703), identified as an oncogene in luminal B breast cancer, is a member of the NET/NlZ family of zinc finger transcription factors. However, the role of ZNF703 in colorectal cancer (CRC) is unknown. We investigated the expression of ZNF703 in paired tumor and corresponding normal tissues us...

journal_title：Oncology reports

authors： Ma F,Bi L,Yang G,Zhang M,Liu C,Zhao Y,Wang Y,Wang J,Bai Y,Zhang Y

更新日期：2014-09-01 00:00:00

abstract：:A patient who had undergone radical gastrectomy for synchronous gastric cancer (T(1)N(0)M(0), stage I) and duodenal cancer (Tis, stage 0) in November 1987 was found to have esophageal cancer in November 1994, and underwent radical thoracolaparotomy at our hospital (T(1)N(0)M(0), stage I). After follow-up for about 3.5...

journal_title：Oncology reports

authors： Mukai M,Makuuchi H,Mukohyama S,Oida Y,Himeno S,Nishi T,Nakazaki H,Satoh S

更新日期：2001-01-01 00:00:00

abstract：:Photodynamic therapy (PDT) using photosensitizer can induce diverse cellular responses, including apoptosis. Recently, it has been reported that PDT using methylaminolaevulinate may be effective in basal cell carcinoma. However, it is largely unknown whether PDT using a natural product such as curcumin can induce apop...

journal_title：Oncology reports

authors： Park K,Lee JH

更新日期：2007-03-01 00:00:00

abstract：:Tumor metastasis is considered the main cause of mortality in cancer patients, thus it is important to investigate the differences between high- and low-metastatic cancer cells. Our previous study showed that the highly metastatic breast cancer cell line MDA-MB-231 released higher levels of ATP and exhibited higher P2...

journal_title：Oncology reports

authors： Eun SY,Ko YS,Park SW,Chang KC,Kim HJ

更新日期：2015-07-01 00:00:00

abstract：:MicroRNAs (miRNAs) are a group of important regulators in human types of cancer including non-small cell lung cancer (NSCLC). miR-616 has been found to be a novel cancer-related miRNA. However, the expression and biological function of miR-616 in NSCLC have not been investigated. In this study, qRT-PCR was performed t...

journal_title：Oncology reports

authors： Wang D,Cao Q,Qu M,Xiao Z,Zhang M,Di S

更新日期：2017-10-01 00:00:00

abstract：:The p53 tumor suppressor is a transcription factor that regulates cell cycle and apoptosis in response to a variety of environmental stress conditions. Recent studies indicated that the apoptotic protease activating factor-1 (Apaf-1) is a direct transcriptional target of p53 in DNA damage-induced apoptosis. However, t...

journal_title：Oncology reports

authors： Ho CK,Bush JA,Li G

更新日期：2003-09-01 00:00:00

abstract：:Although chemotherapy is initially effective in debulking tumor mass in a number of different types of malignancy, tumor cells gradually acquire chemoresistance and frequently progress to advanced clinical stage. Accumulating evidence has indicated that the tumor sensitivity to several chemotherapeutic drugs is regula...

journal_title：Oncology reports

authors： Tomita R,Sasabe E,Tomomura A,Yamamoto T

更新日期：2020-11-01 00:00:00

abstract：:One of the possible ways to augment dendritic cell (DC) efficacy in presentation of tumor antigens to effector T cells is pulsing them with tumor-cell lysates and incubation with certain immunostimulators. We present the results of an immunotherapeutic approach in a murine B78-H1 mo...

journal_title：Oncology reports

authors： Zapała Ł,Wolny R,Wachowska M,Jakóbisiak M,Lasek W

更新日期：2013-03-01 00:00:00

abstract：:Melanoma is a malignant tumor of the melanocytes. microRNAs (miRNAs) are emerging as important regulators of cancer-related processes. A thorough understanding of miRNAs in melanoma progression is important for developing new therapeutic targets. miRNA expression was detected by quantitative PCR. In vitro, MTT assay, ...

journal_title：Oncology reports

authors： Wang HF,Chen H,Ma MW,Wang JA,Tang TT,Ni LS,Yu JL,Li YZ,Bai BX

更新日期：2013-07-01 00:00:00

abstract：:Prognostic factors and the role of post-operative radiotherapy (PORT) in patients with pN1 nodal stage following surgery for NSCLC were identified. The clinical course of 211 patients with pN1 nodal involvement following thoracic surgery were reviewed, 97 of them received PORT. Multi-variate survival analysis with res...

journal_title：Oncology reports

authors： Willner J,Wiens V,Jachmann M,Haubitz I,Flentje M

更新日期：2004-09-01 00:00:00

abstract：:Associations of functional single nucleotide polymorphisms in cytochrome P450 1B1, epoxide hydrolase 1, NAD(P)H:quinone oxidoreductase 1, glutathione S-transferase Pi-1 and deletions of glutathione S-transferases Mu-1 and θ-1 with colorectal cancer risk were investigated in a hospital-based case-control study on 495 m...

journal_title：Oncology reports

authors： Hlavata I,Vrana D,Smerhovsky Z,Pardini B,Naccarati A,Vodicka P,Novotny J,Mohelnikova-Duchonova B,Soucek P

更新日期：2010-11-01 00:00:00

abstract：:Prostate cancer is the second most commonly diagnosed cancer in men in Poland after lung cancer and the third leading cause of cancer-related mortality after lung and colon cancer. The etiology of most cases of prostate cancer are not fully known, and therefore it is essential to search for the molecular basis of pros...

journal_title：Oncology reports

authors： Nowacka-Zawisza M,Wiśnik E

更新日期：2017-11-01 00:00:00

abstract：:Berbamine is an herbal compound derived from Berberis amurensis, which is used in Chinese traditional medicine. However, few studies have investigated this anti-tumor effect or the underlying mechanisms of berbamine on lymphoma cells. We investigate the effect, as well as the mechanism of action, of 4-chlorobenzoyl be...

journal_title：Oncology reports

authors： Du HP,Shen JK,Yang M,Wang YQ,Yuan XQ,Ma QL,Jin J

更新日期：2010-03-01 00:00:00

abstract：:Breast cancer is the most common type of cancer among women worldwide. Research using breast cancer cell lines derived from primary tumors may provide valuable additional knowledge regarding this type of cancer. Therefore, the aim of this study was to investigate the phenotypic prof...

journal_title：Oncology reports

authors： Corrêa NC,Kuasne H,Faria JA,Seixas CC,Santos IG,Abreu FB,Nonogaki S,Rocha RM,Aparecida Borges Silva G,Gobbi H,Rogatto SR,Goes AM,Gomes DA

更新日期：2013-04-01 00:00:00

abstract：:Previous reports showed that breast and gastric cancers overexpressing c-erbB-2 protein have a greater metastatic potential and worse prognosis than tumors in which this protein is not overexpressed. The present study was undertaken to examine the significance of c-erbB-2 protein expression as a prognostic factor in c...

journal_title：Oncology reports

authors： Ishida H,Sadahiro S,Suzuki T,Ishikawa K,Tajima T,Makuuchi H

更新日期：2000-11-01 00:00:00

abstract：:MicroRNA-455 (miR-455) has been considered as a novel cancer-related miRNA and dysregulated expression frequently occurs in various human types of cancer. However, its clinical significance, its biological function and the underlying molecular signaling involved in hepatocellular carcinoma (HCC) remain to be elucidate...

journal_title：Oncology reports

authors： Qin L,Zhang Y,Lin J,Shentu Y,Xie X

更新日期：2016-12-01 00:00:00

abstract：:A phase I study of S-1 and biweekly docetaxel (DOC) combination therapy was conducted to determine the maximum tolerated dose (MTD) and pharmacokinetic parameters. Fourteen patients with advanced or recurrent gastric cancer were analyzed. The treatment consisted of S-1 [body surface area (BSA) <1.25 m2:80 mg/day, 1.25...

journal_title：Oncology reports

authors： Takahashi I,Emi Y,Kakeji Y,Tokunaga E,Ushiro S,Oki E,Watanabe M,Baba H,Maehara Y

更新日期：2006-04-01 00:00:00

abstract：:To investigate the antitumor action of arsenic trioxide (As2O3) by intratumoral injection into solid tumors, tumor growth inhibition (TGI) and angiogenesis of heterotransplanted esophageal carcinoma in mice was carried out. The cultured human esophageal carcinoma cells were inoculated into both laterals of the abdomin...

journal_title：Oncology reports

authors： Shen ZY,Shen J,Chen MH,Wu XY,Wu MH,Zeng Y

更新日期：2003-11-01 00:00:00

abstract：:The aberrant expression of miR107‑5p is closely related to the development of several types of human cancers. However, the role of miR‑107‑5p in endometrial carcinoma (EC) has not been fully confirmed. In the present study, we aimed to explore the function of miR‑107‑5p in EC carcinogenesis. EC samples and normal endo...

journal_title：Oncology reports

authors： Bao W,Zhang Y,Li S,Fan Q,Qiu M,Wang Y,Li Y,Ji X,Yang Y,Sang Z,Xu W,Yang Y,Wu S,Zhu Y

更新日期：2019-03-01 00:00:00

abstract：:Although the impact of vascular endothelial growth factor (VEGF) is clearly established in advanced prostate cancer (PCa), its role in localized PCa remains to be determined. The aim of our study was to analyse the plasma levels of VEGF-A and the expression of VEGF-A in prostatic tissue in a population of patients wit...

journal_title：Oncology reports

authors： Peyromaure M,Badoual C,Camparo P,Grabar S,Goulvestre C,Fulla Y,Vieillefond A,Mao K,Dinh-Xuan AT

更新日期：2007-07-01 00:00:00

abstract：:Correlation between inhibition of cell motility and anti-invasive activity by the water extract of HangAmDan-B (HAD-B), a crude extract of eight Korean medicinal animals and plants, in NCI-H460 human non-small cell lung cancer (NSCLC) cells was investigated. Within the concentration...

journal_title：Oncology reports

authors： Choi YJ,Shin DY,Lee YW,Cho CK,Kim GY,Kim WJ,Yoo HS,Choi YH

更新日期：2011-12-01 00:00:00

abstract：:Metastasis‑associated lung adenocarcinoma transcript 1 (MALAT1) is a long non‑coding RNA (lncRNA) that has an oncogenic role in some types of cancers, uncluding breast cancer (BC). To investigate the role of MALAT1 in human BC progression, we detected MALAT1 expression levels based on tissue samples from 20 BC cases a...

journal_title：Oncology reports

authors： Huang XJ,Xia Y,He GF,Zheng LL,Cai YP,Yin Y,Wu Q

更新日期：2018-11-01 00:00:00

abstract：:As one of the most common malignancies, esophageal squamous cell carcinoma (ESCC) is ranked as the sixth leading cause of cancer-related death worldwide. In our previous study, by employing cDNA microarray analysis, semaphorin 3B (SEMA3B) was found to be significantly downregulated in ESCC. In the present study, SEMA3...

journal_title：Oncology reports

authors： Tang H,Wu Y,Liu M,Qin Y,Wang H,Wang L,Li S,Zhu H,He Z,Luo J,Wang H,Wang Q,Luo S

更新日期：2016-08-01 00:00:00

abstract：:Breast cancer is the most common cancer in women worldwide. Progression and aggressiveness of breast cancer is usually associated with its migration and invasion abilities. Recently, natural products with potential anticancer activity have become attractive candidates for alternative treatment of cancer. A fungal meta...

journal_title：Oncology reports

authors： Kasorn A,Loison F,Kangsamaksin T,Jongrungruangchok S,Ponglikitmongkol M

更新日期：2018-03-01 00:00:00

abstract：:Angiogenesis is a key factor in the growth and dissemination of malignant diseases, including breast cancer, with significant implications for its clinical management. It is known that microRNAs (miRNAs) play important roles in regulating tumor properties in cancers. However, whether miR-497 contributes to breast canc...

journal_title：Oncology reports

authors： Wu Z,Cai X,Huang C,Xu J,Liu A

更新日期：2016-03-01 00:00:00

abstract：:Tropomodulin 3 (TMOD3) is a member of the pointed‑end capping protein family that contributes to invasion and metastasis in several types of malignancies. TMOD3 has been found to be crucial for membranous skeleton and embryonic development; however, little is known regarding the role of TMOD3 in liver cancer progressi...

journal_title：Oncology reports

authors： Jin C,Chen Z,Shi W,Lian Q

更新日期：2019-05-01 00:00:00

abstract：:Previous studies have suggested that certain genetic polymorphisms, specifically the Xeroderma pigmentosum group D (XPD) gene codon 751 and the X-ray repair cross-complementing group 1 (XRCC1) gene codon 399 polymorphisms, were associated with an increased risk of lung cancer, and, in some studies, with a greater risk...

journal_title：Oncology reports

authors： Gao W,Romkes M,Zhong S,Nukui T,Persad RA,Smith PJ,Branch R,Keohavong P

更新日期：2010-07-01 00:00:00

abstract：:As a common malignancy of the endocrine system, papillary thyroid carcinoma (PTC) seriously affects the quality of life of patients. lncRNA PAX8‑AS1:28, or lnc‑PSD4‑1:14 has been reported to be abnormally expressed in PTC. However, the function of PAX8‑AS1:28 in PTC is still unknown. Therefore, the present study aimed...

journal_title：Oncology reports

authors： Zhang Y,Li F,Chen J

更新日期：2019-04-01 00:00:00