Abstract：
:In developed countries, the incidence of end-stage renal failure is constantly increasing, and uremia will soon be a disease typically found in mature and elderly adults. Almost invariably, the physical condition of the elderly patient with terminal uremia is extremely poor, and therapeutic approach complex. Frequent co-morbidity, treatment with many different drugs, the high risk of iatrogenic damage, advanced age and socio-environmental conditions further complicate the management of these patients. While replacement therapy may become necessary, peritoneal dialysis may have advantages over hemodialysis. Peritoneal dialysis causes less hemodynamic stress, does not necessitate vascular access and allows mobility, although it incurs a high incidence of peritonitis and vascular disease. Where hemodialysis is the only feasible treatment, procedures used for vascular access are frequently followed by several complications, representing an important cause of morbidity and hospitalization. In addition, even if it may improve the patient's quality of life, vascular condition, intradialytic hypotension, heart disease, intestinal bleeding and amyloidotic arthropathy are critical aspects of dialysis in the elderly patient. Therefore, particular attention from clinicians and administrators is required and the best possible strategies must be identified in order to provide effective and appropriate services to address these special patients' needs.
journal_name
Kidney Blood Press Resjournal_title
Kidney & blood pressure researchauthors
Buemi M,Lacquaniti A,Bolignano D,Donato V,Fazio MR,Campo S,Coppolino G,Sturiale Adoi
10.1159/000164277subject
Has Abstractpub_date
2008-01-01 00:00:00pages
330-6issue
5eissn
1420-4096issn
1423-0143pii
000164277journal_volume
31pub_type
杂志文章,评审abstract：BACKGROUND/AIM:Calcifications of large arteries are frequent in chronic kidney disease (CKD) and may contribute to the high cardiovascular risk in this population. The aim of this study was to examine whether abdominal aortic calcification volume (AACV) was a predictor of the rate of decline in glomerular filtration ra...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000501687
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND/AIMS:Aortic arch calcification (AoAC) is frequently detected in maintenance hemodialysis (MHD) patients and is associated with cardiovascular and all-cause mortality. We investigated the factors associated with AoAC and analyzed the relationship between the factors including bone-derived biomarkers and AoAC....
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000494441
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND/AIMS:The deposition of β2-microglobulin induced by reactive inflammation causing carpal tunnel syndrome (CTS) is one of the complications of dialysis-related amyloidosis in maintenance hemodialysis (MHD) patients. Air pollution levels, especially particulate matter with an aerodynamic diameter of <2.5 mm (PM...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000484422
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND/AIMS:This study aimed to investigate the potential beneficial anti-proteinuric effect of an add-on aldosterone blockade and the impact of the aldosterone escape phenomenon. METHODS:We retrospectively analyzed data of 304 patients with persistent proteinuria, who were administered spironolactone (25 mg/day) ...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000368470
更新日期：2014-01-01 00:00:00
abstract：AIM:To assess the influence on blood pressure in schoolchildren, of elevated sodium (Na(+)) and nitrate (NO(-)(3)) levels in the drinking water. METHODS:The blood pressure was recorded in three groups of age- and weight-matched schoolchildren (fourth and fifth graders) ingesting differing Na(+) and NO(-)(3) concentrat...
journal_title：Kidney & blood pressure research
pub_type： 临床试验,杂志文章
doi：10.1159/000025989
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND/AIMS:The contribution of preexisting hypercholesterolemia to diabetic nephropathy remains unclear. We assessed the impact of hypercholesterolemia on diabetic nephropathy using a double knockout (DKO) mouse, null for the low-density lipoprotein receptor (LDLRNDASH;/NDASH;) and the apoB mRNA editing catalytic ...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000073942
更新日期：2003-01-01 00:00:00
abstract：:Primary cardiac hemangioma is a very rare benign vascular tumor, with valvular hemangiomas being even less frequent as valves are generally avascular structures. We present the first case of mitral valve hemangioma in a renal transplant recipient. Patient presented with progressive dyspnea. Transesophageal echocardiog...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章,评审
doi：10.1159/000343395
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:Uremic toxins have been shown to promote glomerular hypertrophy. The present study was performed to elucidate the relation between uremic toxins and tubulointerstitial changes. METHODS:Sixty male Sprague-Dawley rats underwent 2/3 nephrectomy (Nx; n = 30) and 4/5 Nx (n = 30). Experiments were initiated 2 wee...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000080935
更新日期：2005-01-01 00:00:00
abstract：:Fibroblast growth factor 23 (FGF23) is released primarily from osteoblasts/osteocytes in bone. In cooperation with the transmembrane protein Klotho, FGF23 is a powerful inhibitor of 1α 25OH Vitamin D Hydroxylase (Cyp27b1) and thus of the formation of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3). As 1,25(OH)2D3 up-regulates ...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章,评审
doi：10.1159/000495393
更新日期：2018-01-01 00:00:00
abstract：BACKGROUNDS:ANCA-associated vasculitis (AAV) frequently present with a chronic relapsing course. Relapse leads to an increased need for therapeutic agents and consequent toxicity. SUMMARY:When referring to the available options for the management of AAV, the efficacy of glucocorticoids (GCs) is unquestionable. However...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章,评审
doi：10.1159/000509608
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND/AIMS:Peritoneal dialysis (PD) has gained interest over the last decade as a viable option for early start dialysis. It is still unknown if shorter break-in periods and less time for proper patient evaluation and training could influence technique survival in comparison to planned-start PD. METHODS:A prospec...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000495386
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND/AIMS:To gain insight into the effect of arginine vasopressin (AVP) on renal hemodynamics in hypertensive rats, we investigated the vasoconstrictive response to AVP on total renal blood flow (RBF) and total and zonal glomerular filtration rate (GFR) in young and old spontaneously hypertensive rats (SHR). A hy...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000054225
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND/AIMS:Cardiovascular morbidity and mortality are high in patients with chronic kidney disease. We evaluated the influence of small differences in preoperative kidney function on mortality and complications following cardiac surgery. METHODS:This is an observational study that included adult patients undergoi...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000335950
更新日期：2012-01-01 00:00:00
abstract：:Acute kidney injury (AKI) is a complex kidney disorder that leads to numerous complications, such as elevated nitrogenous wastes, metabolic acidosis, high potassium levels and even death. The pathogenesis of AKI is very complicated, and its causes are commonly categorized as prerenal, intrinsic or postrenal. In the pa...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章,评审
doi：10.1159/000450566
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND/AIMS:Hypertensive patients present with increased oxidative stress and frequently receive angiotensin II (ANGII) receptor type I blockers (ARB) for blood pressure (BP) reduction. Recent studies revealed an important role of ANGII in maintaining vascular oxidative homeostasis, including sustaining normal sodi...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000450562
更新日期：2016-01-01 00:00:00
abstract：:To clarify whether the ovaries have a potential to attenuate the aggravating effect of testosterone (T) on glomerular injury, we investigated the effect of T in female rats with or without ovaries, using Adriamycin (ADR)-induced nephropathy in female Sprague-Dawley rats. Group 1 consisted of female control rats, group...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000174110
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND/AIMS:To prevent contrast induced renal dysfunction a periprocedural prophylactic hydration is applied. Due to dilution it should cause a drop in serum creatinine concentration (SCR). Surprisingly, no reduction in SCR after contrast admission is found in up to 25% of patients as early as 12-18 hours after cor...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000443425
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND/AIMS:The kinases SPAK (SPS1-related proline/alanine-rich kinase) and OSR1 (oxidative stress-responsive kinase 1) participate in the regulation of the NaCl cotransporter NCC and the Na+, K+, 2Cl- cotransporter NKCC2. The kinases are regulated by WNK (with-no-K[Lys]) kinases. Mutations of genes encoding WNK ki...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000355812
更新日期：2014-01-01 00:00:00
abstract：:Cardiovascular (CV) morbidity and mortality is greatly enhanced in patients with chronic kidney disease, compared to the non-renal population. One key element of this high CV burden appears to be arterial stiffness, as an expression of premature vascular aging. Increased arterial stiffness in renal patients may be a c...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章,评审
doi：10.1159/000100905
更新日期：2007-01-01 00:00:00
abstract：:The value of neutrophil-gelatinase-associated lipocalin (NGAL) was highlighted as a novel biomarker for the detection of acute renal failure. We tested the hypothesis whether NGAL could represent an early biomarker of contrast-induced nephropathy (CIN) in 100 patients with normal serum creatinine values undergoing per...
journal_title：Kidney & blood pressure research
pub_type： 临床试验,杂志文章
doi：10.1159/000109102
更新日期：2007-01-01 00:00:00
abstract：BACKGROUNDS/AIMS:Vitamin C is an antioxidant and acts as a cofactor for several key enzymatic catalytic reactions in animals. Amphibians produce vitamin C in their kidneys, as opposed to mammals that produce vitamin C in their liver. Gulo serves as a crucial enzyme for vitamin C synthesis in mammals, but the characteri...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000450561
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND/AIMS:We examined the factors associated with blood pressure variability in a multi-ethnicity prospective study in China to gain more evidence to guide the prevention and management of hypertension through risk factor intervention. METHODS:A total of 318 consecutive adult subjects aged 29-94 years with suspe...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000477424
更新日期：2017-01-01 00:00:00
abstract：:Patients affected by end-stage renal disease (ESRD) show quite lower physical activity and exercise capacity when compared to healthy individuals. In addition, a sedentary lifestyle is favoured by lack of a specific counseling on exercise implementation in the nephrology care setting. Increasing physical activity leve...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章,评审
doi：10.1159/000355787
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:Treating non-diabetic proteinuric patients with advanced renal disease with an angiotensin-converting enzyme (ACE) inhibitor is still subject to discussion. This study aims to determine the cost-effectiveness of ACE inhibitor therapy in this patient population in the Netherlands. METHODS:We compared two str...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000350142
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND/AIMS:Cardiorenal syndrome type 1 (CRS1) is a syndrome characterized by a rapid worsening of cardiac function leading to acute kidney injury (AKI). The aims of this study were to investigate the risk factors and the prognosis of CRS1 in elderly patients. METHODS:A total of 312 elderly patients (≥60 years old...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000447936
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Magnoline is an active ingredient of magnolia fargesii with anti-inflammatory and anti-platelet effects. The objective is to explore the renoprotection of magnoline in diabetic rats and its effects on P-selectin. METHODS:Thirty-six rats were randomized into 4 groups-normal control group (C), d...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000350146
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND/AIMS:Subclinical hypovolemia may contribute to allograft dysfunction in long-term kidney transplant (KT) patients. In order to predict responsiveness to saline hydration, indices for tubular transport were investigated. METHODS:Fifty-four clinically euvolemic long-term KT patients with recently aggravated a...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000341124
更新日期：2012-01-01 00:00:00
abstract：:The present investigation examined the possible influence of urinary calcium excretion on the concentration of renal calbindin-D28k. Thiazide diuretics stimulate calcium transport across the epithelial cells of the distal tubule, which express calbindin-D28k in high concentrations. Calbindin-D28k is assumed to facilit...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000174153
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND/AIMS:Renalase (gene name RNLS), a recently discovered enzyme with monoamine oxidase activity, is implicated in the degradation of catecholamines. Recent studies indicate that common variations in the gene with RNLS are associated with hypertension. The aim of this study was to examine the association between...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000368460
更新日期：2014-01-01 00:00:00
abstract：INTRODUCTION:Diabetic nephropathy (DN) is a serious complication of diabetes mellitus and is considered to be a sterile inflammatory disease. Increasing evidence suggest that pyroptosis and subsequent inflammatory response play a key role in the pathogenesis of DN. However, the underlying cellular and molecular mechani...
journal_title：Kidney & blood pressure research
pub_type： 杂志文章
doi：10.1159/000508372
更新日期：2020-01-01 00:00:00
