Abstract：
:Nearly every second patient, who needs an oral anticoagulation with vitamin K antagonists, is feasible to perform INR-self-management after participation in a structured teaching program. Patient self-testing or measuring the INR value by relatives or nurses would increase this method of control by the aid of telemedicine systems. An accurately, weekly measurement leads to an optimal therapeutic control of anticoagulation intensity, which results in an impressive risk reduction up to 50%. This depends not on the underlying heart disease and had been demonstrated in patients older than 60 years. Due to the small INR variability and therefore a higher percentage in target range, a lower anticoagulation intensity in patients with mechanical heart valve prosthesis should be justifiable. For the next decade, INR self-management/self-testing should be the method of choice, even direct thrombin inhibitors or factor Xa antagonists would be available. An advantage of INR self-management is the control of drug adherence, which could be an unresolved problem for new anticoagulants.
journal_name
Hamostaseologiejournal_title
Hamostaseologieauthors
Völler H,Braun Ssubject
Has Abstractpub_date
2008-10-01 00:00:00pages
231-3issue
4eissn
0720-9355issn
2567-5761pii
08040231journal_volume
28pub_type
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