Functional nuclear medicine imaging of medullary thyroid cancer.

abstract：:High-grade astrocytoma represents the most common primary malignant brain tumour in the adult, and is associated with high morbidity and mortality rates. The aim of this study was to investigate the prognostic value of 99Tcm-hexamethylpropyleneamine oxime (HMPAO) brain single photon emission computed tomography (SPECT...

journal_title：Nuclear medicine communications

authors： Rodrigues M,Fonseca AT,Salgado D,Vieira MR

更新日期：1993-12-01 00:00:00

abstract：:The ability of 99Tcm-methoxyisobutylisonitrile (MIBI) single photon emission tomography (SPET) to detect myocardial ischaemia and necrosis was assessed in 56 patients (45 male, 11 female, aged 55 +/- 5 years), with clinically recognized ischaemic heart disease (IHD). All underwent coronary angiography (CA) and left ve...

journal_title：Nuclear medicine communications

authors： Sciammarella MG,Fragasso G,Gerundini P,Maffioli L,Cappelletti A,Margonato A,Savi A,Chierchia S

更新日期：1992-12-01 00:00:00

abstract：:Orofacial granulomatosis is a granulomatous inflammatory disorder, affecting the soft tissues of the face and mouth. The predominant feature is disfiguring lip swelling. Patients with this condition may be exhibiting a Type IV hypersensitivity reaction to dietary or environmental allergens, or these may be the orofaci...

journal_title：Nuclear medicine communications

authors： Gibson J,Neilly JB,Wray AP,Evans TJ,MacKenzie JR,McKillop JH

更新日期：2000-02-01 00:00:00

abstract：:An examination of the biokinetics and biodistribution of i.p. administered 131I- or 111In-labelled 791T/36 antibody (1 mg) has been carried out in five patients with stage III/IV ovarian cancer. Blood kinetics and urinary excretion of the radiolabels were assayed. Scintigraphy was performed immediately following admin...

journal_title：Nuclear medicine communications

authors： Perkins AC,Pimm MV,Gie C,Marksman RA,Symonds EM,Baldwin RW

更新日期：1989-08-01 00:00:00

abstract：:The impact of recent advances in the chemical and genetic engineering manipulations of antibodies on radioimmunotargeting is reviewed both in relation to radioimmunoscintigraphy and radioimmunotherapy. The resulting trends are: (1) the linking of parts of the mouse/rat and human antibody molecule; (2) the creation of ...

journal_title：Nuclear medicine communications

authors： Hazra DK,Britton KE,Lahiri VL,Gupta AK,Khanna P,Saran S

更新日期：1995-02-01 00:00:00

abstract：:Ion-exchange resin beads, implanted into connective tissue, were used as the vehicle for the delivery of radiolabelled cations to determine the local distribution of lead, silver and cadmium in loose connective tissue. The system was devoid of systemic toxicity, permitted a predictable release, enabled location of rel...

journal_title：Nuclear medicine communications

authors： Ellender G,Ham KN

更新日期：1988-06-01 00:00:00

abstract：:This paper considers the different statistics that can be derived from studies on the value of diagnostic tests. Well-accepted quantities, such as sensitivity and specificity, are reviewed and the value of the likelihood ratio in communicating particular test results is highlighted. A new quantity, the 'diagnostic val...

journal_title：Nuclear medicine communications

authors： Lloyd JJ,Talbot PR,Lawson RS

更新日期：1998-10-01 00:00:00

abstract：PURPOSE:We assessed the value of N-ammonia PET-computed tomography (PET/CT) in recurrent glioma and compared the results with those of contrast-enhanced MRI (CE MRI). MATERIALS AND METHODS:Fifty-two (mean age, 39.8±11.6 years; male, 33; female, 19) histopathologically proven and previously treated glioma patients with...

journal_title：Nuclear medicine communications

authors： Khangembam BC,Sharma P,Karunanithi S,Singhal A,Das CJ,Kumar P,Julka PK,Bandopadhyaya GP,Kumar R,Malhotra A,Bal C

更新日期：2013-11-01 00:00:00

abstract：:Marked changes in cardiac function have been noted in patients with hyperthyroidism or hypothyroidism due both to changes in sympathetic system function and to biochemical modifications of myocardial tissue. Metaiodobenzylguanidine (MIBG), an analogue of norepinephrine, can be used to evaluate myocardial sympathetic t...

journal_title：Nuclear medicine communications

authors： Maini CL,Tofani A,Sciuto R,Ferraironi A,Festa A,Rea S

更新日期：1999-08-01 00:00:00

abstract：:The method described by Weisner et al. for stabilizing 99Tcm-hexamethylpropylene amine oxime (99Tcm-HMPAO) with cobalt chloride hexahydrate solution is the most promising developed to date. The aim of our work was to study the behaviour of cobalt during the labelling of leukocytes with 99Tcm-HMPAO stabilized in vitro ...

journal_title：Nuclear medicine communications

authors： Prangere T,Bowden AD,Beauchat V,Caulier MT,Ziegels P,Huglo D,Pickett RD,Steinling M

更新日期：1997-03-01 00:00:00

abstract：PURPOSE:Lymphoid hyperplasia is not uncommon in the midline roof of the nasopharynx. Most nasopharyngeal carcinoma patients present with primary tumors in the midline of the nasopharynx. The aim of this study was to evaluate the efficacy of 2-[fluorine-18] fluoro-2-deoxy-D-glucose ((18)F-FDG) PET/computed tomography (C...

journal_title：Nuclear medicine communications

authors： Chen YK,Wang SC,Cheng RH,Yeh CL,Tsui CC,Chia-Hung K

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Scintimammography using (99m)Tc-labelled isonitriles, sestamibi and tetrofosmin, has become a mature technique in the adjunctive setting for the diagnosis of primary breast cancer. To establish an evidence base for its use, clinically, a meta-analysis was performed on both single-site and multi-centre trials...

journal_title：Nuclear medicine communications

authors： Hussain R,Buscombe JR

更新日期：2006-07-01 00:00:00

abstract：:The requirements, problems and progress of radioimmunotherapy in the management of certain malignancies are described. The future prospects using a two- or three-stage approach are promising. ...

journal_title：Nuclear medicine communications

authors： Britton KE,Mather SJ,Granowska M

更新日期：1991-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the potential of (99m)Tc-pamidronate ((99m)Tc-APD) against (99m)Tc-medronate ((99m)Tc-MDP) as a new bone-seeking agent using intact bone and fractured femur in a rat model. METHODS:(99m)Tc-APD was prepared by the stannous reduction method. Scintigraphic images were obtained at 2 h and 24 h after ...

journal_title：Nuclear medicine communications

authors： Kumar V,Kumar D,Howman-Giles RB,Little DG

更新日期：2007-02-01 00:00:00

abstract：:The Monte Carlo code SIMIND is used in nuclear medicine for research purposes, and also for testing the validity of various applications. Conversion of a SIMIND-generated interfile (header and image data file) is required to process the simulated image data on a Xeleris workstation. Currently there is no conversion pr...

journal_title：Nuclear medicine communications

authors： Pandey AK,Kumar JP,Aheer D,Sharma A,Hasan B,Patel C,Bal CS,Kumar R

更新日期：2015-12-01 00:00:00

abstract：:First pass radionuclide angiocardiography (FPRNA) has gained increasing interest because of the development of new 99Tcm-labelled perfusion agents and of new 191Os/191Irm generator systems. The aim of the study was to evaluate the performance capacities of a small field of view single crystal digital gamma camera for ...

journal_title：Nuclear medicine communications

authors： Dobbeleir A,Franken PR,Ham HR,Brihaye C,Guillaume M,Knapp FF,Vandevivere J

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVES:Radioiodine ablation of thyroid tissue remains the cornerstone of treatment for patients with differentiated thyroid carcinoma after thyroidectomy. Selecting an optimal dose of radioiodine for successful ablation is a continuous challenge in these patients. METHODS:We compared the treatment response of 341 ...

journal_title：Nuclear medicine communications

authors： Fallahi B,Beiki D,Takavar A,Fard-Esfahani A,Gilani KA,Saghari M,Eftekhari M

更新日期：2012-03-01 00:00:00

abstract：:Bone scintigraphy has been shown to be sensitive in determining bone involvement in patients with malignancy, but it does not allow the assessment of bone marrow lesions in early disease. The aim of this study was to detect bone marrow invasion using 99Tcm-labelled monoclonal antigranulocyte antibody (AgMoAb) in patie...

journal_title：Nuclear medicine communications

authors： Kiraç S,Duman Y,Cüreklibatur I,Yüksel D,Nazli O,Günaydin G,Taner M

更新日期：1997-10-01 00:00:00

abstract：:In an effort to develop new, clinically useful 99Tcm-diaminodithiol (99Tcm-DADT) complexes for the evaluation of regional cerebral perfusion, basic diaminodithiols (DADT-TM, DADT-HM and DADT-MHM) and three diaminodithiol ligands functionalized with p-iodophenethyl (DADT-IPE), N-ethyl-p-fluorophenethyl amine (DADT-EFPE...

journal_title：Nuclear medicine communications

authors： Shiba K,Mori H,Matsuda H,Hisada K

更新日期：1991-12-01 00:00:00

abstract：:Chronic exertional compartment syndrome (CECS) is currently diagnosed using invasive pressure measurements. We report the use of 99Tcm-methoxyisobutyl isonitrile (99Tcm-MIBI) scintigraphy as a new non-invasive method of diagnosis. Forty-six patients with suspected chronic compartment syndrome underwent graded treadmil...

journal_title：Nuclear medicine communications

authors： Edwards PD,Miles KA,Owens SJ,Kemp PM,Jenner JR

更新日期：1999-03-01 00:00:00

abstract：:Reticuloendothelial system (RES) phagocytic function or capacity can be measured by clearance studies with test substances. This study in the rat examines three commercially available 99Tcm-labelled test substances, and different methods of calculating RES capacity. Albures size 500 nm and sulphur colloid size 600 nm ...

journal_title：Nuclear medicine communications

authors： Holmberg SB,Hafström L,Jacobsson L

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVE:The recent development of mixed ligand complexes using a 99mTc tricarbonyl synthon has prompted us to revisit the first generation product, 99mTc-t-butyl isonitrile (TBI), for possible myocardial imaging after modification of the 99mTc core to a mixed ligand core of carbonyl and t-butyl isonitrile. The easy a...

journal_title：Nuclear medicine communications

authors： Kothari KK,Satpati D,Joshi S,Venkatesh M,Ramamoorthy N,Pillai MR

更新日期：2005-02-01 00:00:00

abstract：:Uterine leiomyomas, benign tumours of the human uterus, are the most common uterine neoplasm and are composed of smooth muscle with varying amounts of fibrous connective tissue. As a functional imaging modality, 2-[F]fluoro-2-deoxy-D-glucose (F-FDG) positron emission tomography can be used to obtain information about ...

journal_title：Nuclear medicine communications

authors： Ak I,Ozalp S,Yalçin OT,Zor E,Vardareli E

更新日期：2004-09-01 00:00:00

abstract：PURPOSE:Despite the growing use of fluorine-18-fluorodeoxyglucose (F-FDG) PET texture analysis to measure intratumoural heterogeneity in cancer research, the biologic basis of F-FDG PET-derived texture variables is poorly understood. We aimed to assess correlations between F-FDG PET-derived texture variables and whole-...

journal_title：Nuclear medicine communications

authors： Bashir U,Foot O,Wise O,Siddique MM,Mclean E,Bille A,Goh V,Cook GJ

更新日期：2018-12-01 00:00:00

abstract：AIM:The aim of this study was to investigate the value of cystatin C and beta-trace protein (BTP) levels in determination of the glomerular filtration rate (GFR) by accepting the technetium-99m diethylenetriamine pentaacetic acid (Tc-DTPA) method as the gold standard for GFR measurement in renal transplant patients wit...

journal_title：Nuclear medicine communications

authors： Oner AO,Aydin F,Demirelli S,Budak ES,Davran F,Akbas H,Kocak H,Suleymanlar G,Gungor F

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The most recent DNA analogues to become commercially available are known as locked nucleic acids (LNAs). The aim of this study was to evaluate the properties of LNAs for antisense targeting. METHODS:A 15 mer LNA antisense to RIalpha mRNA was studied in cell culture. The antisense LNA (5'-amine...

journal_title：Nuclear medicine communications

authors： Zhang Y,He J,Liu G,Venderheyden JL,Gupta S,Rusckowski M,Hnatowich DJ

更新日期：2004-11-01 00:00:00

abstract：:201Tl myocardial perfusion single photon emission tomography (SPET) with pharmacological coronary vasodilatation using adenosine is now often used in the investigation of a patient with ischaemic heart disease (IHD). In this study, we present data from two groups of patients. Group A (n = 40) experienced 201Tl SPET wi...

journal_title：Nuclear medicine communications

authors： Mahmood S,Gupta NK,Gunning M,Bomanji JB,Jarritt PH,Ell PJ

更新日期：1994-08-01 00:00:00

abstract：:This paper describes in vitro cytotoxicity experiments with 213Bi- and 225Ac-immunoconjugates on the human epidermoid tumour cell line A431 using a blood group A-reactive murine IgG (2D11) as the specific antibody and MOPC 21 as the control antibody. With both radionuclides, specific cell-killing was achieved. The obs...

journal_title：Nuclear medicine communications

authors： Kaspersen FM,Bos E,Doornmalen AV,Geerlings MW,Apostolidis C,Molinet R

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:Medullary thyroid carcinoma is a rare, potentially aggressive tumour, with relatively worse prognosis than well-differentiated thyroid cancer. We evaluated the long-term outcomes and prognosis of medullary thyroid carcinoma patients at a single institution in India and compared outcomes based on results of RE...

journal_title：Nuclear medicine communications

authors： Prabhu M,Shakya S,Ballal S,Ahmed Shamim S,Bal C

更新日期：2020-11-01 00:00:00

abstract：:Neuroendocrine tumors (NETs) are rare in childhood. Neuroblastoma is the most common pediatric extracranial solid tumor, occurring >90% in children younger than 5 years of age. Pheochromocytoma and paraganglioma are rare NETs, causing hypertension in 0.5-2% of hypertensive children. Gastroenteropancreatic NETs can occ...

journal_title：Nuclear medicine communications

authors： Haddad T,Fard-Esfahani A,Vali R

更新日期：2021-01-01 00:00:00