Abstract:
:Zolpidem has abuse potential, particularly among individuals with histories of drug abuse. This double-blind, placebo-controlled, cross over pilot study investigated the subjective effects of zolpidem (10 mg) in drug-naïve females. Over the course of a 5-h period vital signs were monitored and a series of computerized questionnaires was administered. Results indicate that zolpidem engendered subjective effects characteristic of hypnotic drugs, but reduced ratings of drug liking, willing to take again, and willing to pay for, relative to placebo. Thus, a therapeutic dose of zolpidem may have limited potential for misuse among females who have no experience with drugs of abuse.
journal_name
Eur J Pharmacoljournal_title
European journal of pharmacologyauthors
Licata SC,Penetar DM,Dunlap S,Lukas SEdoi
10.1016/j.ejphar.2008.09.011subject
Has Abstractpub_date
2008-11-19 00:00:00pages
64-7issue
1-3eissn
0014-2999issn
1879-0712pii
S0014-2999(08)00955-2journal_volume
598pub_type
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