Microimaging FTIR of head and neck tumors. IV.

Abstract:

:On continuing our studies on head and neck neoplasia, specimens from salivary gland tumors have been explored by using infrared microimaging spectroscopy to discern healthy from neoplastic tissues. Samples with Warthin tumor, epithelial displasia, marginal B-cell lymphoma, low-grade adenocarcinoma, and adenoid cystic carcinoma pathologies have been investigated by using conventional light sources. Changes were monitored at the molecular level, probing spectral markers such as Amide I and II, phosphate, nucleic acids, and carbohydrates vibrational modes. In all cases, supervised and unsupervised spectral analyses resulted in satisfactory agreement with histopathological findings.

journal_name

Microsc Res Tech

authors

Conti C,Ferraris P,Garavaglia M,Giorgini E,Rubini C,Sabbatini S,Tosi G

doi

10.1002/jemt.20644

subject

Has Abstract

pub_date

2009-02-01 00:00:00

pages

67-75

issue

2

eissn

1059-910X

issn

1097-0029

journal_volume

72

pub_type

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