Abstract:
AIM:To describe a case of metastasis of malignant peritoneal epithelioid mesothelioma in gastric antral mucosa in a patient with a cryptogenic liver cirrhosis associated with esophageal varices, abdominal pain and distension, ascites, and weight loss. MATERIALS AND METHOD:The patient underwent esophageal gastric endoscopy for varices, and a biopsy of a polypoid antral lesion was performed. The latter revealed a proliferation of polygonal cells with moderately atypical nuclei and pale eosinophilic, peripherally condensed cytoplasm infiltrating into the lamina propria between the normal mucosal glands of the antrum. The tumor cells were diffusely positive to anticalretinin antibody, whereas anti-claudin 4 and anti-CEA antisera were negative. CONCLUSIONS:Metastases of malignant peritoneal mesotheliomas are unusual, and a predominantly gastrointestinal localization is rare. Pathologists should be aware of this possibility to avoid misdiagnosis, particularly in small biopsy specimens.
journal_name
Int J Surg Patholjournal_title
International journal of surgical pathologyauthors
Daniele L,Righi A,Ferraris A,Macrì L,Asioli Sdoi
10.1177/1066896908324257subject
Has Abstractpub_date
2011-04-01 00:00:00pages
217-9issue
2eissn
1066-8969issn
1940-2465pii
1066896908324257journal_volume
19pub_type
杂志文章abstract::Synovial sarcoma is a high-grade sarcoma commonly affecting young adults. The sites of involvement include soft tissue near joints, lung, pleura, mediastinum, larynx, kidney, and buttocks. Histologic types include monophasic, biphasic, and undifferentiated. We report a unique case of synovial sarcoma with low-grade hi...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896917723463
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Cysts of the jaws (JCs) are an important topic of oral pathology, but few epidemiological data are present in the literature, in particular about the potential of recurrence. The aim of this study was to describe a case series of JCs from a single institution, evaluating the frequency, the site, the age dist...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896914541000
更新日期:2014-12-01 00:00:00
abstract::Warthin tumor is the second most common salivary gland neoplasm. It occurs more commonly in males than in females. Malignant transformation in Warthin tumor is a rare but well-recognized phenomenon; however, the development or presentation of lymphoma in a Warthin tumor is rare. An 80-year-old man presented with painl...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896917734371
更新日期:2018-05-01 00:00:00
abstract::Cystic neoplasms of the pancreas are rare and often mistaken for pseudocyst by imaging studies and macroscopic examination. We describe an unusual tumor of the pancreas composed of a mural nodule of anaplastic carcinoma arising from a huge ductal adenocarcinoma undergoing cystic degeneration. The cyst measured 27 x 13...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690301100315
更新日期:2003-07-01 00:00:00
abstract::Sinonasal adenocarcinoma is a rare tumor of the head and neck accounting for 10% to 20% of all primary malignancies of the nose and paranasal sinuses. There tumors are classified as salivary, intestinal and nonintestinal, nonsalivary. Low-grade nonintestinal nonsalivary are rare tumors whose diagnosis is essentially t...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896915599060
更新日期:2015-12-01 00:00:00
abstract::Mixed squamous and glandular papilloma (mixed papilloma) of the lung has been reported in fewer than 25 cases in the English literature. Although it is known as a benign tumor, malignant transformation has been reported. Papillary cystic carcinoma is characterized by papillary and cystic growth patterns and has been r...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920908330
更新日期:2020-09-01 00:00:00
abstract::Composite hemangioendothelioma is a rare vascular tumor morphologically comprising several distinct vascular components and exhibits a borderline malignant potential. We described the case of a 53-year-old female who presented with an infiltrative mass in the paravertebral soft tissue. The tumor showed discrete nests ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920924120
更新日期:2020-10-01 00:00:00
abstract::Carcinomas in the breast with a predominantly clear cytoplasm are rare. In this article, we review the differential diagnosis of clear cell breast neoplasms and report a case of invasive lobular carcinoma with extensive clear cell morphology that was diagnosed as invasive ductal carcinoma, not otherwise specified, on ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896919881705
更新日期:2020-04-01 00:00:00
abstract::In this report, we present for the first time the coexistence of a conventional renal cell carcinoma (RCC) and an undefined Xp11 translocation renal neoplasm in distinct kidneys, which was difficult to definitively classify as either carcinoma or PEComa (perivascular epithelioid cell tumor). While one of the tumors sh...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896915597753
更新日期:2016-05-01 00:00:00
abstract::Gastrointestinal stromal tumors (GIST) are the most common mesenchymal lesions of the gastrointestinal tract. Many are treated surgically with or without the use of adjuvant tyrosine kinase inhibitors. Metastases to lymph nodes are infrequent. In this article, we present a case of a perigastric nodule presenting 3 yea...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896918771192
更新日期:2018-10-01 00:00:00
abstract::The aim of this study was to investigate the role of UbcH10 expression in the differential diagnosis of benign, hyperplastic, and malignant endometrial tissues and also the relationship of UbcH10 with the clinicopathologic parameters of malignant cases. A tissue microarray was performed for 81 endometrial curettage bi...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896912437414
更新日期:2012-08-01 00:00:00
abstract::Ulcerative colitis-related epithelial dysplasia represents a premalignant lesion, which may lead to the development of ulcerative colitis-related adenocarcinoma. The proper management of this condition requires proctocolectomy before the acquisition of the invasive phenotype. Patients with chronic ulcerative colitis, ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690000800106
更新日期:2000-01-01 00:00:00
abstract::SMARCB1 (INI1) deficient sinonasal carcinoma is a recently recognized entity with wide histomorphologic spectrum. We present a case of this carcinoma that contained, in addition to a "common" morphology, scattered foci of yolk sac tumor differentiation. The tumor occurred in paranasal sinuses in a 44-year-old woman. I...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896917741549
更新日期:2018-05-01 00:00:00
abstract::This study describes the clinical, histologic, and immunohistochemical features of four cases of GI PEComa. The size of the tumors ranged from 3.5 to 6.0cm in diameter, and all were located in wall of the large bowel. Microscopically, the tumors were characterized by an epithelioid arrangement of tumor cells, which ha...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896908330481
更新日期:2010-08-01 00:00:00
abstract::Eccrine porocarcinoma is a potentially fatal form of sweat gland carcinoma, due to its propensity to metastasize through lymph vessels. The authors report the case of a 69-year-old female who presented with swelling of the right leg and an ulcerated lesion of the right great toe. The initial histologic diagnosis was i...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896911428738
更新日期:2012-10-01 00:00:00
abstract::Cutaneous glomeruloid hemangioma is a hallmark of POEMS syndrome. These patients have elevated serum levels of vascular endothelial growth factor. The authors report an extracutaneous uterine glomeruloid hemangioma in an 82-year-old woman with a history of breast and endometrial carcinomas. Within the lumen of myometr...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896911429297
更新日期:2012-08-01 00:00:00
abstract::Benign lymphoepithelial cyst (BLC) of the salivary gland is uncommon. Among report of these lesions, there were no previous cases of lymphoepithelial lesion (LeL) in human immunodeficiency virus type-1 (HIV-1) unrelated BLC. This study reports 3 cases of HIV-unrelated BLC containing LeL-like structures. Pathologically...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896908328575
更新日期:2009-12-01 00:00:00
abstract::The authors describe a case of multifocal perivascular epithelioid cell tumor (PEComa) arising in the pelvis of a 39-year-old woman affected by tuberous sclerosis. The tumor presented in the form of multiple fascicular, focally cystic nodules involving the uterine corpus, both ovaries, and the omentum. Microscopically...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896908316067
更新日期:2008-10-01 00:00:00
abstract::Ewing sarcoma (ES) and primitive neuroectodermal tumor (PNET) are round-cell sarcomas with varying degrees of neuroectodermal differentiation; they are considered members of the same family of tumors based on their common genetic profile. ES/PNET are very infrequent in the female genital tract, the vagina being the ra...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896911424898
更新日期:2012-06-01 00:00:00
abstract::Spindle cell neoplasms arising in the testis are uncommon; most cases belong to the category of gonadal stromal tumors, and the presence of distinctive clinical and pathological features usually lead to a definitive diagnosis. In some instances, however, the diagnosis of these tumors can be challenging and special tec...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896908323505
更新日期:2011-02-01 00:00:00
abstract:AIMS:Diffuse large B-cell lymphomas (DLBCL) can be divided into different subgroups (germinal center B-cell-like [GCB] and non-GCB) according to their gene expression profiles. Immunohistochemistry has been proposed as a surrogate for identifying these subgroups, but data about its efficacy in providing prognostic info...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896909345596
更新日期:2011-08-01 00:00:00
abstract::Acinar cell carcinoma of the pancreas is rare, accounting for less than 1% of carcinomas arising in the exocrine pancreas. Patients are typically between the fifth and seventh decade of life and show a 2:1 male predominance. Symptoms tend to be nonspecific, and approximately 50% of the patients have metastases at the ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896909339912
更新日期:2011-12-01 00:00:00
abstract::Spermatocytic tumor, formerly known as spermatocytic seminoma, is an uncommon testicular neoplasm which is a distinct clinicopathologic entity from classic seminoma. These tumors are not associated with germ cell neoplasia in situ, other germ cell tumors, or isochromosome 12p. Although typically, these tumors have an ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896917706156
更新日期:2017-09-01 00:00:00
abstract::Infiltrating ductal carcinoma (IDC) occurs frequently in patients with lobular carcinoma in-situ (LCIS). LCIS is not thought to be the direct precursor of the invasive component. The authors analyzed 15 cases of coexisting LCIS and IDC and found ductal carcinoma in situ (DCIS) in 12. The DCIS and IDC were of similar g...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690100900206
更新日期:2001-04-01 00:00:00
abstract::Primary carcinoid tumor of the skin (PCTS) is an uncommon indolent neoplasm, with 10 cases described in the literature. The tumors affect patients in the sixth to ninth decades of life (mean = 66.3 years) with an equal gender distribution and predilection for the head and trunk. They present as slowly enlarging nodule...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896913516672
更新日期:2014-04-01 00:00:00
abstract::Rhabdomyosarcoma is an aggressive malignant tumor often developing in the head and neck in children. In the sinonasal region, rhabdomyosarcoma constitutes a clinically important group because of the difficulty of surgical resection and its generally poor prognosis. We reviewed the archival pathology materials of 39 ca...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896906299122
更新日期:2007-04-01 00:00:00
abstract::Superficial CD34-positive fibroblastic tumor (SCPFT) is a recently described entity that, despite significant pleomorphism, carries a good prognosis. We briefly describe this tumor and its principal differential diagnoses. Recognition of SCPFTs, including the clinical context in which they arise, is important to avoid...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920938133
更新日期:2020-12-01 00:00:00
abstract::Spitz tumors are a group of melanocytic neoplasms with distinct morphological features that tend to affect young individuals. Distinguishing benign from malignant Spitz tumors can be challenging, but cytogenetic and molecular tests have contributed to improvements in diagnostic accuracy. Spitz tumors harbor diverse ge...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896916630375
更新日期:2016-05-01 00:00:00
abstract::Microvillous inclusion disease (MVID) is a congenital condition presenting with intractable diarrhea. Biopsies demonstrate abnormal apical PAS and CD10 staining in surface enterocytes correlating with the presence of characteristic cytoplasmic inclusions. MVID has been linked to mutations in myosin Vb, important in ap...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896911430959
更新日期:2012-06-01 00:00:00
abstract::Aims Epithelial mesenchymal transition (EMT) is a crucial process for acquisition of malignant phenotype, aggressiveness, and metastatic capacity in neoplasms. It is characterized by loss of epithelial markers and gain of mesenchymal markers. Studies on EMT and its potential association with the histological grading a...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896916654763
更新日期:2016-12-01 00:00:00