Abstract:
:Recurrent aphthous ulcer (RAU) is the most common ulcer of oral non-keratinized mucosa, but the treatment is always limited at present. Considering the multifactorial etiology of RAU, a novel therapeutic agent with multi-bioactivties should be presented. Garlic has been recognized as a favorable natural medicine against a large number of pathologic conditions. The major component of garlic is allicin, which could effectively decrease inflammatory factors secretion, reduce the migration of neutrophils, inhibit bacterium and virus, antagonize oxidation and regulate immunity. By these bioactivities of anti-inflammation, anti-microbial activity, anti-oxidation and immunomodulation, the allicin may be an effective therapeutic candidate to control the pain, promote ulcer healing and prevent the recurrence of RAU.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Jiang XW,Hu J,Mian FIdoi
10.1016/j.mehy.2008.07.028subject
Has Abstractpub_date
2008-12-01 00:00:00pages
897-9issue
6eissn
0306-9877issn
1532-2777pii
S0306-9877(08)00366-6journal_volume
71pub_type
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journal_title:Medical hypotheses
pub_type: 杂志文章
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journal_title:Medical hypotheses
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journal_title:Medical hypotheses
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journal_title:Medical hypotheses
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journal_title:Medical hypotheses
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2014-07-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
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journal_title:Medical hypotheses
pub_type: 杂志文章
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更新日期:2014-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-02-18 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.mehy.2005.01.036
更新日期:2005-01-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章,评审
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更新日期:2008-01-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1016/j.mehy.2006.04.054
更新日期:2007-01-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1054/mehy.2000.1232
更新日期:2001-03-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
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更新日期:2010-11-01 00:00:00
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pub_type: 历史文章,杂志文章
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2008.10.021
更新日期:2009-03-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1054/mehy.2000.1247
更新日期:2001-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/0306-9877(83)90093-2
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pub_type: 杂志文章
doi:10.1016/j.mehy.2003.12.045
更新日期:2004-01-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2006.03.027
更新日期:2006-01-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(95)90056-x
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pub_type: 杂志文章
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