Abstract：
:The aim of the study was to investigate the subacute toxicity of a polychlorinated naphthalene (PCN) mixture and its effect on cytochrome P-450 levels in rats. The animals were administered PCNs intragastrically in repeated daily doses of 1, 10, and 100 mg/kg. The animals were dissected after 7, 14, or 21 doses. Doses of 10 and 100 mg/kg induced a significant decrease in the body weight at all time points of the experiment compared with the control group. The exposure to PCNs increased both the level of total cytochrome P-450 and the activity of CYP 1A at the same time points. In the groups of rats given PCNs in doses of 10 and 100 mg/kg, an evident dose- and time-dependent increase in malondialdehyde (MDA) level was observed throughout the experiment. The correlation between the increased MDA and decreased glutathione (GSH) levels in the liver was also observed.
journal_name
Ecotoxicol Environ Safjournal_title
Ecotoxicology and environmental safetyauthors
Kilanowicz A,Skrzypinska-Gawrysiak M,Sapota A,Galoch A,Daragó Adoi
10.1016/j.ecoenv.2008.07.010subject
Has Abstractpub_date
2009-02-01 00:00:00pages
650-7issue
2eissn
0147-6513issn
1090-2414pii
S0147-6513(08)00185-1journal_volume
72pub_type
杂志文章abstract：:The insecticide imidacloprid and the herbicide sulfentrazone are two different classes of pesticides that are used for pest control in sugarcane agriculture. To evaluate the genotoxic potential of low concentrations of these two pesticides alone and in mixture, the comet assay and the micronucleus (MN) test employing ...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2015.05.040
更新日期：2015-10-01 00:00:00
abstract：:The acute and chronic toxicities of lindane to larvae of the freshwater insects Chironomus riparius Meigen, Chaoborus flavicans (Meigen), and Sigara striata (L.) were investigated in mesocosm compartments of an experimental pond. The following median lethal concentrations (LC50s) were determined: 240-hr LC50 of 2.0 mi...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/0147-6513(92)90023-v
更新日期：1992-02-01 00:00:00
abstract：:An outdoor pot experiment was designed to study the potential of poplar (Populus nigra 'Italica') in phytoremediation of cadmium (Cd) and lead (Pb). Poplar was treated with a combination of different concentrations of Cd (w = 10, 25, 50mgkg-1 soil) and Pb (400, 800, 1200mgkg-1 soil) and several physiological and bioch...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2017.06.011
更新日期：2017-10-01 00:00:00
abstract：:Arsenic is an environmental contaminant, while acetaminophen is an extensively used nonsteroidal analgesic-antipyretic drug. We evaluated whether subacute co-exposure to arsenic and acetaminophen would produce more toxicity than that caused by exposure to either of the xenobiotics in rats. Toxicity was evaluated throu...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2009.09.005
更新日期：2010-01-01 00:00:00
abstract：:Ionic liquids (ILs), a new solvent class composed solely of ions, have already found their way into numerous chemical and biochemical applications. Due to their unique properties and wide application range, research utilizing this new technology for biotechnological applications is steadily increasing. However, progre...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2014.08.032
更新日期：2015-01-01 00:00:00
abstract：:Galaxolide (HHCB) is used as a fragrance ingredient in household and personal care products, and has been ubiquitously detected in the environment. Here we investigated the fate of HHCB in subtropical freshwater microcosms, and evaluated effects of sediment-associated HHCB on a biological community consisting of algae...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2018.11.092
更新日期：2019-03-01 00:00:00
abstract：:Hg and As resistance and bioaccumulation were studied in hydroponically grown Pistacia lentiscus and Tamarix gallica plants. Both elements caused growth inhibition in roots and shoots, with mercury showing greater phytotoxicity than arsenic. Accumulation of both elements by plants increased in response to element supp...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2009.04.022
更新日期：2009-09-01 00:00:00
abstract：:The Deepwater Horizon oil spill contaminated thousands of miles of habitat valuable to hundreds of species of migratory and resident birds of the Gulf of Mexico. Many birds died as a direct result of the oil spill; however, the indirect effects of oil exposure on the flight ability and body condition of birds are diff...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2017.05.012
更新日期：2017-12-01 00:00:00
abstract：:Triclosan (TCS) is an antimicrobial and is an aquatic contaminant. Little is known on aquatic toxicity of TCS. Rotifers are common members of freshwater zooplankton. In this study, Brachionus calyciflorus was chosen as a test organism to assess the acute and complete life cycle toxicity of TCS in this study. The acute...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2015.12.043
更新日期：2016-05-01 00:00:00
abstract：:Three viability assays using fluorescent dyes effectively detected a loss of viability in cultures of three mammalian cell lines (H4IIE, Caco2, and HepG-2), two fish cell lines (RTgill-W1 and RTL-W1), and a ciliated protozoan, Tetrahymena thermophila, after exposure to Triton X-100, used as a model toxicant. The dyes ...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/S0147-6513(03)00083-6
更新日期：2004-03-01 00:00:00
abstract：:Nanoparticles (NPs) are inevitably released into the aquatic environment for being widely used and may affect the toxicity of other contaminants already present in the environment, such as trace metals. However, the effects of NPs on the ecotoxicity of cadmium (Cd), a common environmental trace metal pollutant, are no...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2018.03.007
更新日期：2018-07-30 00:00:00
abstract：:Juvenile rainbow trout (Salmo gairdneri) were exposed to 100 ppb mercury (as HgCl2) in the water for 14 days. Concentrations of mercury in water and fish organs were monitored using radiolabeled mercury. Tissues from kidney and liver were fixed, and sections were developed by autometallography, a method whereby accumu...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/0147-6513(86)90018-7
更新日期：1986-12-01 00:00:00
abstract：:During the past several years, in Germany, a federal government/federal states working group prepared a "guide document for the derivation of quality targets designed to protect inland surface waters against hazardous substances." In May 1993 the 40th Conference of Environment Ministers (Umweltministerkonferenz) adopt...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1006/eesa.1995.1109
更新日期：1995-12-01 00:00:00
abstract：:In this study, Taguchi L₈ experimental design was applied to determine cytotoxic effects of Reactive Blue 33, which is the most toxic azo reactive dye species, on Allium cepa. With this aim, A. cepa test system was performed to achieve targeted experimental design with three factors (concentration of dye, pH and volum...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2013.09.031
更新日期：2013-12-01 00:00:00
abstract：:Male Sprague-Dawley rats were exposed to vapors of 1-nitropropane (1-NP) and 2-nitropropane (2-NP) at air concentrations of 100 ppm for 7 hours per day on four consecutive days. Livers were analyzed for enzymatic activities after 1-, 2-, and 4-day inhalation periods. Liver microsomal cytochrome P450 was depressed by 2...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/0147-6513(92)90075-e
更新日期：1992-06-01 00:00:00
abstract：:Fertilized eggs of zebrafish were exposed under flow-through conditions to several concentrations of the following pesticides: lindane 40, 80, 110, 130, and 150 micrograms/liter; atrazine 300, 1300, and 9100 micrograms/liter; deltamethrin 0.5, 0.8, and 1.2 micrograms/liter. Hatching, abnormalities in development (exte...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/0147-6513(90)90004-o
更新日期：1990-12-01 00:00:00
abstract：:The vitellogenin (VTG) in fish has been used as an important biomarker for monitoring endocrine disrupting compounds (EDCs). This paper reports the development of a new monoclonal antibody (McAb) against the VTG of crucian carp (Carassius carassius). The McAb has a molecular weight of 149.4 kDa (heavy chain: 53.1 kDa;...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2005.11.005
更新日期：2007-02-01 00:00:00
abstract：:A dose-dependent immunomodulatory effect of Nitrogranulogen (NGG) was observed in vitro on antibody-secreting cells and lymphocyte proliferation in rainbow trout. Because different doses of lindane (10, 50 and 100 mg/kg, injected intraperitoneally) had a depressing effect on the same immune functions, the authors rest...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1006/eesa.1994.1025
更新日期：1994-04-01 00:00:00
abstract：:The potential for biodegradation of s-triazine pesticides was investigated in laboratory batch and sequence batch experiments using a stable mixed bacterial community enriched on atrazine. The experiments were performed aerobically in a mineral salt solution complemented with a mixture of s-triazines as sole carbon an...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1006/eesa.1998.1756
更新日期：1999-05-01 00:00:00
abstract：:Adult survival of the springtail Protaphorura armata exposed to pyrene, a common soil pollutant, was investigated in combination with cold and drought stress, in three separate experiments. (1) A drought stress imposed subsequent to pyrene exposure in soil resulted in a significant decrease in springtail survival, whe...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/S0147-6513(02)00144-6
更新日期：2004-02-01 00:00:00
abstract：:This study investigated metal accumulation and oxidative effects in mantle, gill and digestive gland of the ribbed mussel Aulacomya atra from the Argentinean North Patagonian coastline. Mussels were transplanted over an 18-month period from a site with low anthropogenic impact to a harbor site with higher seawater con...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2018.02.064
更新日期：2018-07-15 00:00:00
abstract：:Acute hazard classification based on selected microbiotests was proposed to assess and compare the toxicity of rivers including surface-water, sediment and soil from floodplains. No direct relationship between the classification of pollution for surface-water based on physical-chemical parameters and proposed acute ha...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2008.02.023
更新日期：2008-11-01 00:00:00
abstract：:Polycyclic aromatic hydrocarbons (PAHs) are toxic to both plants and animals. The enhancement of plant tolerance and detoxification capacity is important for the plant-based remediation of PAHs. Therefore, we investigated the effects of 24-epibrassinolide (EBR) on the metabolism of a three-ringed PAH (phenanthrene-PHE...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2012.02.004
更新日期：2012-06-01 00:00:00
abstract：:The objective of this study was to detect red blood cell (rbc) DNA abnormalities in male, game-farm mallard ducks as they ranged freely and accumulated 137Cs (radiocesium) from an abandoned nuclear reactor cooling reservoir. Prior to release, the ducks were tamed to enable recapture at will. Flow cytometric measuremen...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/0147-6513(91)90073-x
更新日期：1991-06-01 00:00:00
abstract：:This study indicates that complex mixtures of pollutants found in the Arctic marine environment have genotoxic effects in glaucous gulls (Larus hyperboreus). DNA adducts were quantified, by the (32)P-postlabeling technique, in liver samples from gulls fed with hen eggs (controls) and from gulls fed with environmentall...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2004.12.023
更新日期：2005-11-01 00:00:00
abstract：:Excessive cadmium (Cd) in rice grains is of great concern worldwide, particularly in southern China where heavy metal pollution in the soil is widespread. Much work has been done regarding the key genes responsible for Cd absorption, transport, and accumulation in rice, but little is known about the differences of Cd ...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2019.109795
更新日期：2019-12-30 00:00:00
abstract：:The in vivo toxic effects of hexavalent chromium (20 mg/liter) on hemolymph glucose, tissue glycogen, total free sugars, and active and total phosphorylases of an edible, freshwater crab Barytelphusa guerini were studied. In a 15-day exposure span followed by a 15-day postexposure recovery, the time-course alterations...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/0147-6513(90)90042-4
更新日期：1990-08-01 00:00:00
abstract：:Mercury (Hg) concentrations were determined in human urine and hair samples from Gouxi (GX, n=25) and Laowuchang (LWC, n=18), Tongren, Guizhou, China, to evaluate human exposure from artisanal Hg mining. Geometric means of urinary Hg (U-Hg) were 216 and 560 μg g(-1) Creatinine (μg g(-1) Cr) for artisanal mining worker...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2010.10.030
更新日期：2011-03-01 00:00:00
abstract：:Ozone (O3) is one of the most harmful air pollutants to crops, contributing to high losses on crop yield. Tropospheric O3 background concentrations have increased since pre-industrial times reaching phytotoxic concentrations in many world regions. Capsicum peppers are the second most traded spice in the world, but few...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2013.09.035
更新日期：2014-02-01 00:00:00
abstract：:Animals living in aquatic habitats regularly encounter anthropogenic chemical pollution. Typically, the toxicity of a chemical toxicant is determined by the median lethal concentration (LC50) through a static exposure test. However, LC50 values and static tests do not provide an accurate representation of exposure to ...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2016.10.015
更新日期：2017-01-01 00:00:00
