Abstract:
:New insights on the high prevalence of functional decompensation of the thyroid among newborn and children from several states of India as well as neighbouring countries of Nepal and Bhutan helped to prevent nutritional iodine deficiency and iodine deficiency disorders through country-wide iodized salt prophylaxis. Presently on the basis of scientific studies, salt iodization in India is saving millions of children from neonatal hypothyroidism related psycho-physical retardation.
journal_name
Rev Endocr Metab Disordjournal_title
Reviews in endocrine & metabolic disordersauthors
Kochupillai N,Mehta Mdoi
10.1007/s11154-008-9094-0subject
Has Abstractpub_date
2008-09-01 00:00:00pages
237-44issue
3eissn
1389-9155issn
1573-2606journal_volume
9pub_type
杂志文章,评审abstract::Pituitary tumors are among the most common neoplasms in man; they account for approximately 15% of all primary intracranial lesions (Jagannathan et al., Neurosurg Focus, 19:E4, 2005). Although almost never malignant and rarely clinically expressed, pituitary tumors may cause significant morbidity in affected patients....
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-007-9066-9
更新日期:2008-03-01 00:00:00
abstract::With the dramatically increasing prevalence of obesity and type 2 diabetes mellitus (T2DM) worldwide, there is an urgent need for new strategies to combat the growing epidemic of these metabolic diseases. Diet is an essential factor affecting the development of and risk for obesity and T2DM and it can either help or h...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-014-9302-z
更新日期:2015-03-01 00:00:00
abstract:UNLABELLED:We aimed to review and summarize the evidence from accomplished trials analyzing factors influencing mortality in patients with T2DM and to provide some recommendations for targets and treatment in the European region. The following databases were searched for relevant trials: PubMed and the Cochrane Library...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-016-9349-0
更新日期:2016-03-01 00:00:00
abstract::Lifestyle changes such as dietary habits, sedentary life and consumption of energy-dense foods that have occurred over the years has led to an epidemic of abdominal obesity, which in turn resulted in dramatic increase in the prevalence of metabolic syndrome (MetS). Different expert panels have provided various definit...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-013-9268-2
更新日期:2013-09-01 00:00:00
abstract::T3 suppression of TSH subunit gene transcription is an important step in maintaining thyroid hormone homeostasis, and recent investigations have increased our understanding of this process. Thyrotrope-specific proteins play a critical role in TSH subunit gene expression, and influence T3-mediated regulatory mechanisms...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1023/a:1010008318961
更新日期:2000-01-01 00:00:00
abstract::The 13th Acromegaly Consensus Conference was held in November 2019 in Fort Lauderdale, Florida, and comprised acromegaly experts including endocrinologists and neurosurgeons who considered optimal approaches for multidisciplinary acromegaly management. Focused discussions reviewed techniques, results, and side effects...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-020-09588-z
更新日期:2020-12-01 00:00:00
abstract::Methionine and folate are the key components of one carbon metabolism, providing the methyl groups for numerous methyl transferase reactions via the ubiquitous methyl donor, s-adenosyl methionine. Methionine metabolism is responsive to nutrient intake, is regulated by several hormones and requires a number of vitamins...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-012-9215-7
更新日期:2012-06-01 00:00:00
abstract::Obstructive sleep apnea (OSA) is a common disorder associated with cardiovascular disease (CVD). One theory to explain this relationship proposes that OSA can induce systemic inflammation, thereby inducing CVD. This theory is based on the premise that obesity is a pro-inflammatory state, and that physiological derange...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-014-9304-x
更新日期:2015-03-01 00:00:00
abstract::The peak in incidence for schizophrenia is during late adolescence for both sexes, but within this time frame the peak is both earlier and steeper for males. Additionally, women have a second peak in incidence following menopause. Two meta-analyses have reported that men have an overall ∼40% greater chance of developi...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-011-9184-2
更新日期:2012-09-01 00:00:00
abstract::The ovarian steroid hormones progesterone and estradiol are well established regulators of human endometrial function. However, more recent evidence suggests that androgens and locally generated steroids, such as the glucocorticoids, also have a significant impact on endometrial breakdown and repair. The temporal and ...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-012-9228-2
更新日期:2012-12-01 00:00:00
abstract::Prediabetes is a heterogeneous term that encompasses different origins of insulin resistance and insulin secretion that contribute to distinct patterns of hyperglycemia. In fact, prediabetes is an umbrella term that characterizes individuals at high risk for developing type 2 diabetes (T2D) and/or cardiovascular disea...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-016-9352-5
更新日期:2016-03-01 00:00:00
abstract::The skeletal muscle is one of the major target organs of insulin and plays an essential role in insulin-induced glucose uptake. Some evidence indicates that insulin delivery to skeletal muscle interstitium through the endothelial cells is the rate-limiting step in insulin-stimulated glucose uptake. Researchers have al...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-013-9242-z
更新日期:2013-06-01 00:00:00
abstract::Glucokinase is a key enzyme involved in regulating insulin secretion from the pancreatic ß-cell. The unique role of glucokinase in human glucose physiology is illustrated by the fact that genetic mutations in glucokinase can either cause hyperglycaemia or hypoglycaemia. Heterozygous inactivating mutations in glucokina...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-010-9147-z
更新日期:2010-09-01 00:00:00
abstract::Myo-inositol (Myo-Ins) plays an important role in thyroid function and autoimmunity. Myo-Ins is the precursor for the synthesis of phosphoinositides, which takes part in the phosphatidylinositol (PtdIns) signal transduction pathway, and plays a decisive role in several cellular processes. In the thyroid cells, PtdIns ...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-018-9477-9
更新日期:2018-12-01 00:00:00
abstract::A clustering of metabolic abnormalities such as dyslipidemia, hypertension, and diabetes mellitus, all of which are major risk factors for cardiovascular disease (CVD), occurs more often than by chance. Numerous epidemiological studies, as well as basic researches, have revealed that visceral fat accumulation is close...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-014-9294-8
更新日期:2014-12-01 00:00:00
abstract::Ectopic Cushing's syndrome usually relates to the ectopic ACTH syndrome (EAS) and represents ∼20% of ACTH-dependent and ∼10% of all types of Cushing's syndrome (CS). Nearly any neuroendocrine or non-endocrine tumours may be associated with EAS, but the more prevalent tumours are bronchial carcinoids, small cell lung c...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-010-9139-z
更新日期:2010-06-01 00:00:00
abstract::The adult endocrinologist may be asked to consult on a patient for unexplained biochemical disturbances that could be caused by an underlying inborn error of metabolism. A genetic disorder is generally less likely to be the cause as these disorders are individually rare, however inborn errors of metabolism are collect...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-018-9444-5
更新日期:2018-03-01 00:00:00
abstract::Vitamin D is a key hormone involved in the regulation of calcium/phosphorous balance and recently it has been implicated in the pathogenesis of sub-inflammation, insulin resistance and obesity. The two main forms of vitamin D are cholecalciferol (Vitamin D3) and ergocalciferol (Vitamin D2): the active form (1,25-dihyd...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-017-9423-2
更新日期:2017-06-01 00:00:00
abstract::Abdominal obesity and elevated blood pressure commonly occur in the same patient and are key components of the metabolic syndrome. However, the association between obesity and increased blood pressure is variable. We review mechanisms linking cardiovascular and metabolic disease in such patients including altered syst...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-016-9348-1
更新日期:2016-03-01 00:00:00
abstract::The hypothalamic pituitary adrenal (HPA) axis is the most common of the endocrine lines/axis' to be affected by HIV infection. There are multiple factors that contribute to this HPA axis dysregulation. Direct invasion of the various organs in the axis can be either by opportunistic infections or infiltrative diseases....
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-013-9244-x
更新日期:2013-06-01 00:00:00
abstract::Coronary artery disease (CAD) continues to be the most common cause of morbidity and mortality in patients with diabetes mellitus (DM). In recent years, the strategies for treatment of CAD in DM have undergone much evolution. Currently, all patients with DM, regardless of symptoms or diagnosed CAD, are treated aggress...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-010-9129-1
更新日期:2010-03-01 00:00:00
abstract::Worldwide prevalence of diabetes mellitus in the adult population is increasing and when explicitly searched within specific groups of patients, as those presenting cardiovascular disease (CVD), dysglycaemia is detected in about three-quarters of the patients. Dysglycaemia alone is a major risk factor for microvascula...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-010-9136-2
更新日期:2010-03-01 00:00:00
abstract::Neuroendocrine neoplasms (NENs) comprise a heterogeneous group of tumors, mainly localized in the gastrointestinal system. What characterizes NENs is the expression of hormone receptors on the tumor cell surface, making them accessible for diagnostic and therapeutic approaches (theranostics) using radiolabelled peptid...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-020-09552-x
更新日期:2020-06-03 00:00:00
abstract::Bone health is a major lifelong concern in caring for women and girls with Turner syndrome (TS). There is an approximately 25% increase in fracture risk most of which is related to medium or high impact trauma. The long bones, especially of the forearm are predominantly affected. This fact may be due to a selective co...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-008-9076-2
更新日期:2008-06-01 00:00:00
abstract::The carcinoid as originally described is part of the relatively large family of neuroendocrine neoplasia found in almost every organ. Historical reasons back their current definitions. Neuroendocrine cancer is most frequently observed in the lung and the digestive tract. In the lung is defined as carcinoid (typical an...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-017-9428-x
更新日期:2017-12-01 00:00:00
abstract::The incidence of neuroendocrine tumors (NET) increases with age. Lately, the diagnosis of NET was mainly caused by early detection of small NET (<1 cm) in the rectum and stomach, which are depicted by chance during routine and prophylactic endoscopy. Also in patients with large and metastatic pancreatic and intestinal...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-018-9469-9
更新日期:2018-06-01 00:00:00
abstract::In the last 10 years, several studies have shown that the pancreas of patients with type 1 diabetes (T1D), and even of subjects at risk for T1D, was smaller than the pancreas from healthy subjects. This arose the question of the relationships between the endocrine and exocrine parts of the pancreas in T1D pathogenesis...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-019-09501-3
更新日期:2019-06-01 00:00:00
abstract::The term "HCV syndrome" encompasses several organ- and systemic pathophysiological states, which often recognize autoimmunity or neoplastic evolution in their pathophysiology, as well as chronic HCV infection as trigger. The clinical features of HCV patients are heterogenous, and may include endocrine or metabolic dis...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-018-9475-y
更新日期:2018-12-01 00:00:00
abstract::The incidence of both type 2 and type 1 diabetes mellitus has been increasing worldwide. Vitamin D deficiency, or the awareness of its prevalence, has also been increasing. Vitamin D may have a role in the pathogenic mechanisms predisposing to type 2 diabetes by modulating insulin resistance and/or pancreatic β-cell f...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-016-9403-y
更新日期:2017-06-01 00:00:00
abstract::Incretin hormones are intestinally derived peptides that are known to augment glucose-stimulated insulin secretion and suppress glucagon levels. Incretin mimetics are attractive adjunctive therapy for type 2 diabetes due to its efficacy on reducing hyperglycemia with a minimal risk of hypoglycemia. In contrast to most...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-011-9170-8
更新日期:2011-09-01 00:00:00