The periprostatic autonomic nerves--bundle or layer?

Abstract:

BACKGROUND:The functional outcome of a nerve-sparing radical prostatectomy (RP) depends on the knowledge of autonomic nerve distribution in correlation to the prostate. OBJECTIVE:Recent literature has focused predominantly on the anterior prostate; this study evaluates the nerve distribution on the entire prostate, using a two-dimensional approach. DESIGN, SETTING, AND PARTICIPANTS:From 17 non-nerve-sparing (NS) RP specimens, 77 whole mounted serial sections were immunostained with PGP9.5 and analyzed. INTERVENTION:Each prostate half was divided into 12 sectors (three levels: apex, mid-part, base; four courses: anterior, anterolateral, posterolateral, posterior). MEASUREMENTS:The extracapsular nerves were counted and classified by size (>200microm or

journal_name

Eur Urol

journal_title

European urology

authors

Sievert KD,Hennenlotter J,Laible I,Amend B,Schilling D,Anastasiadis A,Kuehs U,Nagele U,Stenzl A

doi

10.1016/j.eururo.2008.06.007

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

1109-16

issue

5

eissn

0302-2838

issn

1873-7560

pii

S0302-2838(08)00668-4

journal_volume

54

pub_type

杂志文章
  • Outcomes for Patients with Clinical Lymphadenopathy Treated with Radical Prostatectomy.

    abstract:UNLABELLED:Clinical lymphadenopathy (cN+) from prostate cancer (PCa) identified on imaging remains a contraindication to radical prostatectomy (RP) according to guidelines. We tested the hypothesis that there would be no difference in survival between patients with and without cN+ on preoperative imaging who underwent ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2015.07.047

    authors: Moschini M,Briganti A,Murphy CR,Bianchi M,Gandaglia G,Montorsi F,Quevedo JF,Carlson R,Kwon E,Karnes RJ

    更新日期:2016-02-01 00:00:00

  • 'True' sarcomatoid carcinoma of the renal pelvis. First case report with immunocytochemical study.

    abstract::A case of sarcomatoid carcinoma of the renal pelvis is reported. The neoplasm showed polypoid configuration and was composed exclusively of plump, spindle and pleomorphic cells. Light microscopy did not reveal any epithelial differentiation of the neoplastic cells. Immunoperoxidase staining for keratins and for epithe...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000463827

    authors: Piscioli F,Bondi A,Scappini P,Luciani L

    更新日期:1984-01-01 00:00:00

  • Long-term Outcomes After Bladder-preserving Tri-modality Therapy for Patients with Muscle-invasive Bladder Cancer: An Updated Analysis of the Massachusetts General Hospital Experience.

    abstract:BACKGROUND:Tri-modality therapy (TMT) is a recognized treatment strategy for selected patients with muscle-invasive bladder cancer (MIBC). OBJECTIVE:Report long-term outcomes of patients with MIBC treated by TMT. DESIGN, SETTING, AND PARTICIPANTS:Four hundred and seventy-five patients with cT2-T4a MIBC were enrolled ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2016.12.020

    authors: Giacalone NJ,Shipley WU,Clayman RH,Niemierko A,Drumm M,Heney NM,Michaelson MD,Lee RJ,Saylor PJ,Wszolek MF,Feldman AS,Dahl DM,Zietman AL,Efstathiou JA

    更新日期:2017-06-01 00:00:00

  • Combined effect of tumor necrosis factor alpha and anticancer chemotherapeutic agents against human renal carcinoma cell lines.

    abstract::Antitumor effect of recombinant human tumor necrosis factor alpha (TNF) alone or in combination with various anticancer chemotherapeutic agents was tested using an in vitro antiproliferative assay on four human renal carcinoma cell lines (VMRC-RCW, VMRC-RCZ, Caki-1 and A-498). When the dose-dependent effect of TNF was...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000473628

    authors: Ikemoto S,Hayahara N,Wada S,Nishio S,Maekawa M

    更新日期:1991-01-01 00:00:00

  • Urinary BTA-stat, BTA-trak and NMP22 in surveillance after TUR of recurrent superficial transitional cell carcinoma of the bladder.

    abstract:OBJECTIVES:To evaluate NMP22, BTA-Stat and BTA-Trak tests in monitoring recurrent transitional cell carcinoma of the bladder. METHODS:The tests were performed in 179 selected patients being followed up for recurrent superficial bladder tumors: 55 patients had bladder recurrence and 124 patients were recurrence free. T...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000020318

    authors: Serretta V,Pomara G,Rizzo I,Esposito E

    更新日期:2000-10-01 00:00:00

  • Microvascular changes in the early stage of reflux pyelonephritis. An experimental study in the pig kidney.

    abstract::Renal microvascular changes were studied in the pig kidney during the initial stage of reflux pyelonephritis. In 10 piglets vesicoureteric reflux was surgically induced. The animals were then infected with a strain of Escherichia coli and sacrificed 2 weeks following the initiation of infection. Following injection of...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000472782

    authors: Androulakakis PA,Ransley PG,Risdon RA,Sorger K,Hohenfellner R

    更新日期:1987-01-01 00:00:00

  • Histopathologic analysis of peritumoral pseudocapsule and surgical margin status after tumor enucleation for renal cell carcinoma.

    abstract:BACKGROUND:The oncologic safety of blunt tumor enucleation (TE) of renal cell carcinoma (RCC) depends on the presence of a continuous pseudocapsule (PS) around the tumor and on the possibility of obtaining negative surgical margins (SMs). OBJECTIVE:To investigate the PS and SMs after TE to define the real need to take...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2008.07.038

    authors: Minervini A,di Cristofano C,Lapini A,Marchi M,Lanzi F,Giubilei G,Tosi N,Tuccio A,Mancini M,della Rocca C,Serni S,Bevilacqua G,Carini M

    更新日期:2009-06-01 00:00:00

  • Absence of brain parenchymal damage following intravascular injection of polytetrafluoroethylene paste.

    abstract:OBJECTIVE:Polytetrafluoroethylene (PTFE) paste has been used for over 30 years to treat urinary incontinence and for 14 years to treat vesicoureteral reflux with little reported morbidity. Some investigators have been concerned by the use of PTFE as the implanted substance, because migration of PTFE particles from the ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000019720

    authors: Miyakita H,O'Briain DS,Puri P

    更新日期:1998-09-01 00:00:00

  • Further experiences with the specific red cell adherence test (SRCA) in bladder cancer. a histological and cytological study.

    abstract::The red cell adherence test allows the disclosure of the blood group antigens incorporated on the surface of the urothelium. In the course of dedifferentiation the urothelium will lose its antigenicity. We applied this test on superfical bladder tumours (T1), carcinoma in situ and cytological specimens and observed a ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000473993

    authors: Jakse G,Hofstädter F

    更新日期:1978-01-01 00:00:00

  • Incidence of normocalcemic hyperparathyroidism in idiopathic hypercalciuria: evaluation by dietary calcium deprivation test.

    abstract::Calcium metabolism was studied in 37 patients with "idiopathic hypercalciuria" on a home diet and after 10 days of low calcium dietary intake (less than 400 mg/24h). After low calcium intake, urinary calcium excretion returned to within normal limits in 70% of the cases. In the group of patients which failed to respon...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000473258

    authors: Mazzuoli GF,D'Erasmo E,Minisola S,Mancini D,Malaguti Aliberti L,Scarda A,Bracci U,Miano L

    更新日期:1981-01-01 00:00:00

  • Lethal Prostate Cancer in the PLCO Cancer Screening Trial.

    abstract::The Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial randomized men to usual care or annual prostate-specific antigen (PSA) screening for 6 yr and digital rectal examination for 4 yr. This trial found no difference between the intervention and usual care arms of the study in the primary end point ...

    journal_title:European urology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.eururo.2016.01.009

    authors: Shoag J,Mittal S,Halpern JA,Scherr D,Hu JC,Barbieri CE

    更新日期:2016-07-01 00:00:00

  • Genomic Drivers of Poor Prognosis and Enzalutamide Resistance in Metastatic Castration-resistant Prostate Cancer.

    abstract:BACKGROUND:Metastatic castration-resistant prostate cancer (mCRPC) is the lethal form of the disease. Several recent studies have identified genomic alterations in mCRPC, but the clinical implications of these genomic alterations have not been fully elucidated. OBJECTIVE:To use whole-genome sequencing (WGS) to assess ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2019.03.020

    authors: Chen WS,Aggarwal R,Zhang L,Zhao SG,Thomas GV,Beer TM,Quigley DA,Foye A,Playdle D,Huang J,Lloyd P,Lu E,Sun D,Guan X,Rettig M,Gleave M,Evans CP,Youngren J,True L,Lara P,Kothari V,Xia Z,Chi KN,Reiter RE,Maher

    更新日期:2019-11-01 00:00:00

  • Solifenacin in Children and Adolescents with Overactive Bladder: Results of a Phase 3 Randomised Clinical Trial.

    abstract:BACKGROUND:Solifenacin, an effective, well-tolerated treatment for adult overactive bladder (OAB) symptoms, has not been evaluated in placebo-controlled paediatric clinical trials. OBJECTIVES:To evaluate the efficacy and safety of once-daily oral solifenacin suspension in OAB patients aged 5-<12 yr (children) and 12-<...

    journal_title:European urology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.eururo.2016.08.061

    authors: Newgreen D,Bosman B,Hollestein-Havelaar A,Dahler E,Besuyen R,Sawyer W,Bolduc S,Rittig S

    更新日期:2017-03-01 00:00:00

  • Changes in renal function following nephroureterectomy may affect the use of perioperative chemotherapy.

    abstract:BACKGROUND:Nephroureterectomy alone fails to adequately treat many patients with advanced upper tract urothelial carcinoma (UTUC). Perioperative platinum-based chemotherapy has been proposed but requires adequate renal function. OBJECTIVE:Our aim was to determine whether the ability to deliver platinum-based chemother...

    journal_title:European urology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.eururo.2010.06.029

    authors: Kaag MG,O'Malley RL,O'Malley P,Godoy G,Chen M,Smaldone MC,Hrebinko RL,Raman JD,Bochner B,Dalbagni G,Stifelman MD,Taneja SS,Huang WC

    更新日期:2010-10-01 00:00:00

  • The 111 Study: A Single-arm, Phase 3 Trial Evaluating One Cycle of Bleomycin, Etoposide, and Cisplatin as Adjuvant Chemotherapy in High-risk, Stage 1 Nonseminomatous or Combined Germ Cell Tumours of the Testis.

    abstract:BACKGROUND:Standard management in the UK for high-risk stage 1 nonseminoma germ cell tumours of the testis (NSGCTT) is two cycles of adjuvant bleomycin, etoposide (360 mg/m2), and cisplatin (BE360P) chemotherapy, or surveillance. OBJECTIVE:To test whether one cycle of BE500P achieves similar recurrence rates to two cy...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2019.11.022

    authors: Cullen M,Huddart R,Joffe J,Gardiner D,Maynard L,Hutton P,Mazhar D,Shamash J,Wheater M,White J,Goubar A,Porta N,Witts S,Lewis R,Hall E,111 Trial Management Group.

    更新日期:2020-03-01 00:00:00

  • Normocalcemic hyperparathyroidism.

    abstract::10 patients with normocalcemic secondary hyperparathyroidism due to renal hypercalciuria and 1 patient with normocalcemic primary hyperparathyroidism are presented. The diagnostic criteria of both manifestations of disturbed calcium metabolism are outlined. Successful therapeutic approach depends on the exact discrimi...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000473257

    authors: Zechner O,Kovarik J,Willvonseder R

    更新日期:1981-01-01 00:00:00

  • Who should be treated and how? Evidence-based medicine in symptomatic BPH.

    abstract::The management of benign prostatic hyperplasia (BPH), although based on the best available evidence, should be individualised to patients' circumstances and personal choices. Subjective symptoms (LUTS), bothersomeness and negative impact on the quality of life are the main reasons for the patient to seek treatment for...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000052348

    authors: Speakman MJ

    更新日期:1999-01-01 00:00:00

  • The natural history and predictors of outcome following biochemical relapse in the dose escalation era for prostate cancer patients undergoing definitive external beam radiotherapy.

    abstract:BACKGROUND:The management of biochemical failure (BF) following external beam radiotherapy (EBRT) for prostate cancer is controversial, due to both the heterogeneous disease course following a BF and a lack of clinical trials in this setting. OBJECTIVE:We sought to characterize the natural history and predictors of ou...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2014.09.028

    authors: Zumsteg ZS,Spratt DE,Romesser PB,Pei X,Zhang Z,Polkinghorn W,McBride S,Kollmeier M,Yamada Y,Zelefsky MJ

    更新日期:2015-06-01 00:00:00

  • Clinical study of the longitudinal deformation of the flaccid penis and of its variations with aging.

    abstract::The length changes of the flaccid penis provoked by a maximum manual stretching of the glans have been measured in 905 men in order to study its biomechanical qualities. Our study shows that the flaccid penis is deformable, extensible and elastic in its longitudinal axis. The analysis of the variations of these biomec...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000474858

    authors: Bondil P,Costa P,Daures JP,Louis JF,Navratil H

    更新日期:1992-01-01 00:00:00

  • A systematic review of the literature on the prevalence of sexual impairment in women with urinary incontinence and the prevalence of urinary leakage during sexual activity.

    abstract:OBJECTIVE:To provide a synthesis of the literature concerning the impact of urinary incontinence on sexual lives of women and the prevalence of urinary incontinence during sexual activity. METHODS:Medline and PsycInfo were searched for all primary epidemiological articles reporting the prevalence of sexual incontinenc...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1016/s0302-2838(02)00401-3

    authors: Shaw C

    更新日期:2002-11-01 00:00:00

  • Long-term alpha-adrenergic-blocking therapy in detrusor-urethra dyssynergia.

    abstract::Neurogenic dyssynergia was treated with alpha-adrenergic blockers. Only 21 of 43 highly selected patients with residual urines and low flow rates continued therapy with phenoxybenzamine for more than 6 months, despite initial benefits. The causes of therapy discontinuation are discussed. A combination of 5 mg dibenzyl...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000474074

    authors: Vereecken RL,Van Poppel H,Boeckx G,Leruitte A

    更新日期:1983-01-01 00:00:00

  • Three-year Safety of Radium-223 Dichloride in Patients with Castration-resistant Prostate Cancer and Symptomatic Bone Metastases from Phase 3 Randomized Alpharadin in Symptomatic Prostate Cancer Trial.

    abstract:BACKGROUND:In Alpharadin in Symptomatic Prostate Cancer (ALSYMPCA) trial, radium-223 versus placebo prolonged overall survival with favorable safety in castration-resistant prostate cancer patients with symptomatic bone metastases. Long-term radium-223 monitoring underlies a comprehensive safety and risk/benefit assess...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2017.06.021

    authors: Parker CC,Coleman RE,Sartor O,Vogelzang NJ,Bottomley D,Heinrich D,Helle SI,O'Sullivan JM,Fosså SD,Chodacki A,Wiechno P,Logue J,Seke M,Widmark A,Johannessen DC,Hoskin P,James ND,Solberg A,Syndikus I,Kliment J,Wedel

    更新日期:2018-03-01 00:00:00

  • Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma.

    abstract:BACKGROUND:Relative telomere length in peripheral blood leukocytes has been evaluated as a potential biomarker for renal cell carcinoma (RCC) risk in several studies, with conflicting findings. OBJECTIVE:We performed an analysis of genetic variants associated with leukocyte telomere length to assess the relationship b...

    journal_title:European urology

    pub_type: 杂志文章,meta分析,多中心研究

    doi:10.1016/j.eururo.2017.07.015

    authors: Machiela MJ,Hofmann JN,Carreras-Torres R,Brown KM,Johansson M,Wang Z,Foll M,Li P,Rothman N,Savage SA,Gaborieau V,McKay JD,Ye Y,Henrion M,Bruinsma F,Jordan S,Severi G,Hveem K,Vatten LJ,Fletcher T,Koppova K,Larsso

    更新日期:2017-11-01 00:00:00

  • Proposal for a "European Scoring System for Laparoscopic Operations in Urology".

    abstract:PURPOSE:To propose a scoring system of difficulties for the most currently performed laparoscopic procedures in urology. MATERIALS AND METHODS:Each current laparoscopic procedure has been evaluated according to three different criteria: technical difficulty, operative risk and the attention required. Each criterion is...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000049742

    authors: Guillonneau B,Abbou CC,Doublet JD,Gaston R,Janetschek G,Mandressi A,Rassweiler JJ,Vallancien G

    更新日期:2001-07-01 00:00:00

  • Thermoregulation during transurethral microwave thermotherapy: experimental and clinical fundamentals.

    abstract::Transurethral microwave thermotherapy of 340 patients treated at our center for benign prostatic hypertrophy shows the importance of the role played by two thermoregulation processes during the procedure. The first one is artificial and automatically driven by the machine (the power output and cooling rate are adjuste...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000474683

    authors: Devonec M,Berger N,Fendler JP,Joubert P,Nasser M,Perrin P

    更新日期:1993-01-01 00:00:00

  • Cytokine Panel for Response to Intravesical Therapy (CyPRIT): Nomogram of Changes in Urinary Cytokine Levels Predicts Patient Response to Bacillus Calmette-Guérin.

    abstract:UNLABELLED:The response of non-muscle-invasive bladder cancer (NMIBC) to intravesical immunotherapy with bacillus Calmette-Guérin (BCG) depends on adequate stimulation of an immune response. Although BCG has been used for decades, we lack tools to accurately predict response in individual patients. To address this defi...

    journal_title:European urology

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.eururo.2015.06.023

    authors: Kamat AM,Briggman J,Urbauer DL,Svatek R,Nogueras González GM,Anderson R,Grossman HB,Prat F,Dinney CP

    更新日期:2016-02-01 00:00:00

  • Oncologic outcome and patterns of recurrence after salvage radical prostatectomy.

    abstract:BACKGROUND:Limited data on patterns of recurrence (local or metastatic) after salvage radical prostatectomy (SP) is available. OBJECTIVE:To examine biochemical, local and metastatic patterns of recurrence in patients undergoing SP for radiation-recurrent prostate cancer. DESIGN, SETTING, AND PARTICIPANTS:146 patients...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2008.07.007

    authors: Paparel P,Cronin AM,Savage C,Scardino PT,Eastham JA

    更新日期:2009-02-01 00:00:00

  • Renal cysts. II. Chemical and dynamic study of cystic fluid.

    abstract::The chemical analysis of the fluid obtained by puncturing 100 simple renal cysts in adults show that the composition of cystic fluid resembles that of interstitial fluid. The chemical balance between cystic fluid and the interstitial space seems to occur passively. Antibiotics which were given orally (amoxycilline, mi...

    journal_title:European urology

    pub_type: 杂志文章

    doi:

    authors: Steg A

    更新日期:1976-01-01 00:00:00

  • Sexual functioning of adult patients born with meningomyelocele. A pilot study.

    abstract:OBJECTIVES:This pilot study was started to get an impression of the sexual activity and sexual difficulties of adult patients born with meningomyelocele in control at Utrecht University Hospital, and to find out whether these problems deserve more attention from the Spina Bifida Team. METHODS:Seventeen patients (9 men...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000019673

    authors: Vroege JA,Zeijlemaker BY,Scheers MM

    更新日期:1998-01-01 00:00:00

  • Urothelial histopathology surrounding bladder carcinomas.

    abstract::We studied the histological condition of the urothelium surrounding bladder carcinomas in 65 patients who underwent partial resection of the bladder. These examinations showed that urothelial abnormalities were always present, i.e. a direct transition from tumour to normal urothelium was never observed. The histologic...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000472763

    authors: Brünger R,Schubert GE

    更新日期:1987-01-01 00:00:00