Abstract：
:The infectivity of the H9N2 virus to MDCK cells was time-dependently inhibited by Cu(2+) at concentrations of 2.5-250 microM. In 25 microM Cu(2+) solution, the virus titer decreased by approximately 3 and 4 log within 3 and 6 h, respectively. Compared to Cu(2+), Zn(2+) was much less effective in virus inactivation. The H9N2 virus hemagglutinin activity was not affected by 2.5-250 microM Cu(2+). The H9N2 virus neuraminidase (NA) activity was drastically reduced by 25 mM Cu(2+), marginally reduced by 250 microM Cu(2+), and not affected by 25 microM Cu(2+). Thus, we found that copper ions suppress the infectivity of influenza virus at lower concentrations at which neither NA nor hemagglutination inhibition occurs. Electron microscopic analysis revealed morphological abnormalities of the Cu(2+)-treated H9N2 virus. Additional studies should be undertaken to clarify the mechanism underlying the antiviral effect of copper ions on influenza virus.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Horie M,Ogawa H,Yoshida Y,Yamada K,Hara A,Ozawa K,Matsuda S,Mizota C,Tani M,Yamamoto Y,Yamada M,Nakamura K,Imai Kdoi
10.1007/s00705-008-0154-2subject
Has Abstractpub_date
2008-01-01 00:00:00pages
1467-72issue
8eissn
0304-8608issn
1432-8798journal_volume
153pub_type
杂志文章abstract：:Since serological donor-screening tests for HIV were introduced in 1985, the safety of donated blood components has improved dramatically. However, these tests do not completely prevent the risk of transfusion-associated HIV infection related to the use of blood donated during the pre-seroconversion window period. Tes...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-011-1085-x
更新日期：2011-11-01 00:00:00
abstract：:The RNAs of 4 avian rotavirus isolates were analysed by polyacrylamide gel electrophoresis. One of these isolates was made from chickens, the other three were from turkeys. The RNAs were separated into 8 or 9 bands consisting of 11 segments, ranging in molecular weight from 0.24 X 10(6) to 2.09 X 10(6). In contrast to...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01320765
更新日期：1980-01-01 00:00:00
abstract：:Pseudocowpox is a zoonosis caused by pseudocowpox virus (PCPV), which mainly affects cows but can be an occupational disease of humans. The aim of the study was to validate a quantitative polymerase chain reaction (qPCR) assay for the detection of PCPV. The assay was able to detect up to 1000 copies of PCPV per µL in ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04872-4
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abstract：:Chronic hepatitis C virus (HCV) infection often leads to liver cancer. The HCV NS2 protein is a hydrophobic transmembrane protein that associates with several cellular proteins in mammalian cells. In this report, we investigated the function of NS2 protein on HCV replication and translation by using a transient cell-b...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0198-3
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abstract：:Degenerate primers were used to detect and amplify 3'-terminal genome fragments of potyviruses from medicinal aroid plants growing at 16 sites in China. Virus was detected in 7 samples of which six, all of Pinellia ternata, contained a strain of soybean mosaic virus (SMV) similar to that previously reported from this ...
journal_title：Archives of virology
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doi：10.1007/s00705-004-0390-z
更新日期：2005-01-01 00:00:00
abstract：:vp1, a gene encoding one of the capsid proteins of Taura syndrome virus, was cloned into the pGEX-6P-1 expression vector, and the resulting construct was then used to transform E. coli strain BL21. After induction, an N-terminally glutathione-S-transferase-tagged VP1 (GST-VP1) protein with a molecular mass of 80 kDa w...
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pub_type： 杂志文章
doi：10.1007/s00705-012-1460-2
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journal_title：Archives of virology
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doi：10.1007/s00705-016-2919-3
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pub_type： 杂志文章,评审
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0784-1
更新日期：2006-11-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章,评审
doi：10.1007/s00705-001-0792-0
更新日期：2002-06-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-005-0660-4
更新日期：2006-02-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3548-1
更新日期：2017-12-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1247-5
更新日期：2012-05-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01320788
更新日期：1981-01-01 00:00:00
abstract：:Since the first rescue of a recombinant Newcastle disease virus (rNDV) in the late 1990s, many more rNDVs have been rescued by researchers around the world. Regardless of methodology, the main principle behind rescue of the virus has remained the same, i.e., the formation of a functional replication complex by simulta...
journal_title：Archives of virology
pub_type： 杂志文章,评审
doi：10.1007/s00705-016-3065-7
更新日期：2017-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章,评审
doi：10.1007/s00705-019-04494-5
更新日期：2020-02-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314428
更新日期：1987-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317004
更新日期：1985-01-01 00:00:00
abstract：:Porcine circovirus type 2 (PCV2) is the etiological agent associated with several pig diseases that are collectively referred to as porcine circovirus-associated disease (PCVAD). Unfortunately, PCV2 has had a serious economic impact on the swine industry. In this study, we report the genome sequence of a novel PCV2 is...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2615-8
更新日期：2015-12-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-003-0139-0
更新日期：2003-10-01 00:00:00
abstract：:Establishment of a persistent infection of Spodoptera frugiperda nuclear polyhedrosis virus (NPV) in Spodoptera frugiperda (S.f.) cells occurred in three phases: the first phase was characterised by high levels of cell infection and death, the second phase by decreasing cell infection levels leading to the final phase...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310859
更新日期：1983-01-01 00:00:00
abstract：:We determined the genome sequence of a new polerovirus that infects field pea and faba bean in China. Its entire nucleotide sequence (6021 nt) was most closely related (83.3% identity) to that of an Ethiopian isolate of chickpea chlorotic stunt virus (CpCSV-Eth). With the exception of the coat protein (encoded by ORF3...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1301-3
更新日期：2012-07-01 00:00:00
abstract：:The individual structural polypeptides of HVJ (haemagglutinating virus of Japan--the Sendai strain of parainfluenza 1 virus) were examined by tryptic peptide analysis. [3H]-methionine-labelled structural proteins of the wild-type virus of HVJ (HVJ-W) and [35S]-methionine-labelled corresponding constituent proteins of ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01320600
更新日期：1979-01-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/s00705-007-1073-3
更新日期：2008-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-013-1706-7
更新日期：2013-10-01 00:00:00
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pub_type： 杂志文章
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更新日期：2007-01-01 00:00:00
abstract：:Norovirus has captured increasing attention as an agent of childhood diarrhoea. However, it is not known whether norovirus causes as severe diarrhoea as rotavirus, particularly among children in developing countries. In a 1-year study conducted between May 2004 and April 2005 in Recife, Brazil, norovirus was detected ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0060-7
更新日期：2008-01-01 00:00:00
abstract：:A group of previously isolated heterogeneous mEp lambdoid phages (43) from 19 different immunity groups for phage infection was further characterized to gain insight into some phenotypic traits and to assess their relationship with phage lambda. Interestingly, the FhuA host receptor was required by the majority of mEp...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0111-0
更新日期：2008-01-01 00:00:00
abstract：:RNA viruses are classified by their genome polarity and replication strategies. Nucleotide composition and codon usage differ among virus groups, for instance positive-sense RNA (+ssRNA) viruses have higher GC-content than the other RNA virus groups. Codon usage of +ssRNA viruses is closer to humans showing significan...
journal_title：Archives of virology
pub_type： 杂志文章
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更新日期：2018-10-01 00:00:00
abstract：:This is the first report on the morphology and fine structure of chlorella virus Göttingen-1 (CVG-1), an European member of the newly approved family Phycodnaviridae, which infects certain unicellular, eukaryotic, exsymbiotic, green algae. CVG-1 are polyhedral particles 145-160 nm in diameter. The capsid consists of t...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01319003
更新日期：1993-01-01 00:00:00
