Pentacyclic triterpenoids from the mangrove plant Rhizophora stylosa.

abstract：:Biotransformation of corosolic acid (1) by Cochliobolus lunatus and Streptomyces asparaginoviolaceus afforded four metabolites, which were identified by using (1)H NMR, (13)C NMR, DEPT, HSQC, HMBC and NOESY spectral data. Biotransformation of corosolic acid by C. lunatus R.R. Nelson & Haasis CGMCC 3.4381 produced thre...

journal_title：Natural product research

authors： Feng X,Li DP,Zhang ZS,Chu ZY,Luan J

更新日期：2014-01-01 00:00:00

abstract：:Evaluation of in vitro standard antioxidant assays, such as 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2'-azino-bis-3 ethylbenzothiozoline-6-sulphonic acid diammonium salt (ABTS+) radical scavenging, lipid peroxidation inhibitory (or thiobarbituric acid formation inhibitory activity) and ferrous ion (Fe+2) chelating acti...

journal_title：Natural product research

authors： Chakraborty K,Raola VK

更新日期：2018-11-01 00:00:00

abstract：:Protein kinase C (PKC) plays a key role in neurotransmission in the central nervous system, and targeting PKC domain is considered as a strategy to modulate the anaesthetic effects. In this study, we described a synthetic pipeline to perform high-throughput virtual screening against a large library of 3D structural na...

journal_title：Natural product research

authors： Zhao J,Zhou C

更新日期：2015-01-01 00:00:00

abstract：:A series of new thiazolyl chalcones, 1-[2-amino-4-methyl-1,3-thiazol-5-yl]-3-aryl-prop-2-en-1-one were prepared by piperidine mediated Claisen-Schmidt condensation of thiazolyl ketone with aromatic aldehyde. These chalcones on cyclisation gave 2-amino-6-(2-amino-4-methyl-1,3-thiazol-5-yl)-4-aryl-4H-pyridine-3-carbonit...

journal_title：Natural product research

authors： Venkatesan P,Maruthavanan T

更新日期：2012-01-01 00:00:00

abstract：:Phytochemical investigation of Gymnocarpos decandrus roots lead to the isolation, characterization and evaluation of four compounds: the bis-coumarin daphnoretin, two biflavonoids: wikstrol A and wikstol B in addition to β-sitosterol glucoside. Their structures were established via spectroscopic data. The crude root e...

journal_title：Natural product research

authors： Fathy H

更新日期：2019-05-13 00:00:00

abstract：:The aqueous methanolic extracts of Melastoma malabathricum L. exhibited antibacterial activity when assayed against seven microorganisms by the agar diffusion method. Solvent fractionation afforded active chloroform and ethyl acetate fractions from the leaves and the flowers, respectively. A phytochemical study result...

journal_title：Natural product research

authors： Wong KC,Hag Ali DM,Boey PL

更新日期：2012-01-01 00:00:00

abstract：:Resinous exudate obtained from the aerial parts of Adesmia boronioides Hook.f. were evaluated to determine anti-phytopathogenic effects. Briefly, resinous exudate was obtained by dipping fresh plant material in dichloromethane; chemical composition was determined by GC-MS; and minimum inhibitory concentration (MIC) an...

journal_title：Natural product research

authors： Montenegro I,Valenzuela M,Zamorano N,Santander R,Baez C,Madrid A

更新日期：2019-08-06 00:00:00

abstract：:Proximate composition of the seeds and chemical analysis of the oils of Lonchocarpus sericeus and Lonchocarpus cyanescens were determined. The oil content of the seed of L. cyanescens is 29.71 ± 0.20% while that of L. sericeus is 28.00 ± 0.50%. The seeds as well as the oils of L. cyanescens and L. sericeus were found ...

journal_title：Natural product research

authors： Adewuyi A,Oderinde RA,Rao BV,Prasad RB

更新日期：2012-01-01 00:00:00

abstract：:The chemical composition of the essential oils obtained from the fresh leaves of Cinnamomum tamala Nees et Eberm. was determined by GC and GC-MS. The yield of the oil on a dry weight basis ranged from 1.2% to 3.9% (w/w). Phenyl propanoids constitute the major portion (88.9-95.0%) of the oils. Fifty-four compounds were...

journal_title：Natural product research

authors： Rana VS,Langoljam RD,Verdeguer M,Blázquez MA

更新日期：2012-01-01 00:00:00

abstract：:Camptothecin (CPT), the derivatives of which are used clinically for the treatment of metastatic colon cancer, is isolated from intact plants that can be subjected to environmental fluctuations. In vitro cultures may be an alternate and continuous source for year-round production of CPT. Since CPT production by undiff...

journal_title：Natural product research

authors： Kamble S,Gopalakrishnan R,Eapen S

更新日期：2011-10-01 00:00:00

abstract：:A new protopine alkaloid, protomexicine and a new isoflavonoid, mexitin, together with 8-methoxydihydrosanguinarine, 13-oxoprotopine, rutin and quercetrin have been isolated from the aerial part of the methanolic extract of Argemone mexicana. The structures of these compounds have been established by various spectral ...

journal_title：Natural product research

authors： Singh S,Pandey VB,Singh TD

更新日期：2012-01-01 00:00:00

abstract：:Two flavonoid glycosides containing acetylated allose, and two iridoid glucosides were obtained from a EtOH extract of Stachys corsica, an endemic plant of Sardinia and Corsica. All the compounds have previously been isolated from other species of Stachys. ...

journal_title：Natural product research

authors： Serrilli AM,Ramunno A,Piccioni F,Serafini M,Ballero M

更新日期：2005-09-01 00:00:00

abstract：:In this study, phenolic compounds of hazelnut leaves of 10 different cultivars with the same cultural, geographical, geological and climatic conditions were analyzed by HPLC/DAD and HPLC/DAD/MS/MS - ESI. Eight phenolic compounds (3-caffeoylquinic acid, 5-caffeoylquinic acid, caffeoyltartaric acid, p-coumaroyltartaric ...

journal_title：Natural product research

authors： Amaral JS,Ferreres F,Andrade PB,Valentão P,Pinheiro C,Santos A,Seabra R

更新日期：2005-02-01 00:00:00

abstract：:Diphysidione (1), a new p-hydroxyphenyl anhydride, and vitexin (2) were isolated from the leaves of Diphysa carthagenensis. The structure of the new metabolite was characterised as 4-(4-hydroxy-phenyl)-3H-pyran-2,6-dione using 1D and 2D NMR spectroscopy. ...

journal_title：Natural product research

authors： Torres-Tapia LW,Sosa-Espinosa T,Peraza-Sánchez SR

更新日期：2013-01-01 00:00:00

abstract：:Cinobufagin was one of the important cardenolidal steroids and a major component of Chan'Su, a famous traditional Chinese medicine. The urinary metabolites of cinobufagin after single oral doses of 25 mg kg⁻¹ in rats were investigated. Eleven metabolites were isolated and purified by liquid-liquid extraction, open-col...

journal_title：Natural product research

authors： He X,Hu H,Wu Y,Zeng X

更新日期：2012-01-01 00:00:00

abstract：:One new tirucallane-type nortriterpenoid Nortirucallane A (1), together with Chrysoeriol (2) and Isorhamnetin (3), was isolated from the methylene chloride part of Lonicerae japonicae flos. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compound 3 was isolated from the g...

journal_title：Natural product research

authors： Wang X,Zhang J,Li YQ,Du BX,Sun QH,Cao YJ,Jiang HQ,Liu YH,Zhou HL,Rong R

更新日期：2017-10-01 00:00:00

abstract：:The world's rainforests hold untold potential for drug discovery. Rainforest plants are thought to contain evolved defensive active metabolites of greater diversity compared to plants from temperate regions. In recent years, the interest and overall output from pharmaceutical companies on novel antibacterial agents ha...

journal_title：Natural product research

authors： Othman M,Genapathy S,Liew PS,Ch'ng QT,Loh HS,Khoo TJ,Wiart C,Ting KN

更新日期：2011-11-01 00:00:00

abstract：:The hexane and ethanol extracts from Himatanthus bracteatus (Apocynaceae) stems were evaluated for antiviral activity against Zika virus, yellow fever virus and dengue virus 2 and for cytotoxicity in Vero cells by MTT assay. The ethanol extract showed good antiviral activity against the three viruses with selective in...

journal_title：Natural product research

authors： da Silva ML,Stehmann JR,Serafim MSM,Vale VV,Gontijo DC,Brandão GC,Kroon EG,de Oliveira AB

更新日期：2019-11-20 00:00:00

abstract：:The oral squamous cell carcinoma (OSCC) is the eighth more common cancer in men. The development of new and more efficient drugs is needed. Plants of the genus Piper are popularly used in the treatment of many diseases. This study evaluated the antitumor effect of extract, fraction and isolated compounds from leaves o...

journal_title：Natural product research

authors： Fonseca ACCD,de Queiroz LN,Sales Felisberto J,Jessé Ramos Y,Mesquita Marques A,Wermelinger GF,Pontes B,de Lima Moreira D,Robbs BK

更新日期：2020-10-14 00:00:00

abstract：:From the ethanolic extract of Lentinus edodes (Shiitake) eight known sterols were isolated and identified: ergosterol, ergosterol peroxide, (22E)-ergosta-5,7,9(11), 22-tetraen-3beta-ol, (22E)-ergosta-7,9(11),22-trien-3beta-ol, (22E)-ergosta-6,8,22-trien-3beta-ol, (22E)-norergosta-5,7,9,22-tetraen-3beta-ol, 3beta,5alph...

journal_title：Natural product research

authors： Rivera A,Benavides OL,Rios-Motta J

更新日期：2009-01-01 00:00:00

abstract：:A new 5-O-beta-D-glucopyranosyl-4-(4-hydroxyphenyl)-7-methoxy-2H-chromen-2-one (1), together with four known compounds, one coumarin, 5-O-beta-D-galactopyranosyl-4-(4-hydroxyphenyl)-7-methoxy-2H-chromen-2-one (2) and three cucurbitacins, 23,24-dihydrocucurbitacin F (3), 23,24-dihydro-25-acetylcucurbitacin F (4) and 2-...

journal_title：Natural product research

authors： Olmedo D,Rodríguez N,Vásquez Y,Solís PN,López-Pérez JL,Feliciano AS,Gupta MP

更新日期：2007-06-01 00:00:00

abstract：:The antiradical activity of the freshwater bryozoan Hyalinella punctata water extracts (two samples, seasonal collection) was evaluated by using electron paramagnetic resonance spectroscopy against hydroxyl (√OH), superoxide anion (√O2(- )), methoxy (√CH2OH), carbon-dioxide anion (√CO2(- )), nitric-oxide (√NO) and 2,2...

journal_title：Natural product research

authors： Pejin B,Savic AG,Hegedis A,Karaman I,Horvatovic M,Mojovic M

更新日期：2014-01-01 00:00:00

abstract：:Members of the family Zygophyllaceae are distributed in arid areas of the world and are traditionally used against various health insults ranging from skin lesions to lethal cancer. Fagonia cretica Linn. is a plant having novel compounds responsive in diseases that are still considered as incurable or are curable with...

journal_title：Natural product research

authors： Qureshi H,Asif S,Ahmed H,Al-Kahtani HA,Hayat K

更新日期：2016-01-01 00:00:00

abstract：:Among phenolic compounds, Agave americana L. extract contained puerarin (38.4%) and p-coumaric acid (12.29%) (pCa). From the Lineweaver-Burk plots, pCa and puerarin demonstrated a competitive and a non competitive inhibitions towards human α-amylase activity, respectively. PCa exhibited a higher human inhibitory activ...

journal_title：Natural product research

authors： Sahnoun M,Bejar S,Daoud L,Ayadi L,Brini F,Saibi W

更新日期：2019-03-01 00:00:00

abstract：:New sesquiterpene glycoside, cyclodipeptide and piperidine derivative were isolated from Streptomyces sp. YIM 63342. On the basis of spectral data, their structures were determined as 3R, 5R, 6S, 7E, 9R-megastigman-7-en-3,5,6,9-tetrol-9-O-β-D-apiofuranosyl-(1→ 2)-β-D-glucopyranoside (1), cyclo (L-Pro-L-OMet) (2) and (...

journal_title：Natural product research

authors： Yang XQ,Yang YB,Zhou H,He GW,Zhao LX,Xu LH,Ding ZT

更新日期：2013-01-01 00:00:00

abstract：:Three new phenanthrenone constituents, trigoxyphins U-W (1, 7 and 9), together with eight known ones, trigoxyphin M (2), 6,9-O-dimethyltrigonostemone (3), trigonstemone (4), thrigonosomone B (5), trigonochinene E (6), actephiiol A (8), epiactephilol A (10) and neoboutomannin (11), were obtained from the methanol extra...

journal_title：Natural product research

authors： Li SF,He HP,Hao XJ

更新日期：2015-01-01 00:00:00

abstract：:Essential oils derived from six different phenophases, namely early vegetative stage, late vegetative stage, early flowering stage, full flowering stage (FFS), late flowering stage and seed shattering stage of Origanum vulgare L. grown in Kumaon region of Uttarakhand, India were investigated by GC and GC-MS. A total o...

journal_title：Natural product research

authors： Verma RS,Padalia RC,Chauhan A

更新日期：2012-01-01 00:00:00

abstract：:Extracts obtained from Cyrtocarpa procera Kunth were evaluated to determine their toxicity on Artemia salina Leach. All the extracts showed a significant activity. Bioguided fractionation of these extracts led to the isolation of beta-sitosterol and the identification of 1,3-propyl-dipentadecanoate, 3-hydroxypropyl-9-...

journal_title：Natural product research

authors： Rodríguez-López V,Aguirre-Crespo F,Salazar L,Estrada-Soto S

更新日期：2006-01-01 00:00:00

abstract：:A simple and efficient method was developed for simultaneous analysis of five illegal residual β2-agonists in cattle hair. β2-Agonists were quantified by ultra high performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry operating in positive multiple-reaction monitoring mode. T...

journal_title：Natural product research

authors： Di Stefano V,Pitonzo R,Giaccone V,Alongi A,Macaluso A,Cicero N,Cancemi G,Ferrantelli V

更新日期：2017-02-01 00:00:00

abstract：:Two phytotoxic furan derivatives were isolated, together with the well-known fungal and plant phytotoxin tyrosol, from the culture filtrates of Stilbocrea macrostoma. This fungal pathogen isolated from Quercus brantii trees induced wood necrosis and decline symptoms on the host plant in Iran. The two furan derivatives...

journal_title：Natural product research

authors： Di Lecce R,Bashiri S,Masi M,Alioto D,Tuzi A,Abdollahzadeh J,Evidente A

更新日期：2020-10-05 00:00:00