Abstract：
:Thermal and nociceptive cutaneous stimuli activate the brain via two types of nerve fibers, slightly myelinated Adelta-fibers with moderate conduction velocity and unmyelinated C-fibers with slow conduction velocity. Differences in central processing upon selective stimulation of these two fiber types in healthy human subjects still remain poorly understood. By means of event-related functional magnetic resonance imaging the present study investigated brain activation in response to stimulation of Adelta- and C-fibers in healthy subjects. We used the stimulation of tiny skin areas to perform a selective stimulation upon cutaneous C-fibers. Besides similar activation in several brain areas in response to both kinds of stimulation, we observed pronounced brain activation to selective C-fiber stimulation as compared to Adelta-fiber stimulation in the right frontal operculum and anterior insula. Based on a putative function of these structures we suggest that the C-fiber system might be engaged in homeostatic and interoceptive functions in a manner other than the Adelta-fiber system, producing a signal of greater emotional salience.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Weiss T,Straube T,Boettcher J,Hecht H,Spohn D,Miltner WHdoi
10.1016/j.neuroimage.2008.03.047subject
Has Abstractpub_date
2008-07-15 00:00:00pages
1372-81issue
4eissn
1053-8119issn
1095-9572pii
S1053-8119(08)00284-Xjournal_volume
41pub_type
杂志文章相关文献
NEUROIMAGE文献大全abstract：:Trust is an important component of human social life. Within the brain, the function within a neural network implicated in interpersonal and social-cognitive processing is associated with the way trust-based decisions are made. However, it is currently unknown how localized structure within the healthy human brain is ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2014.11.060
更新日期：2015-02-15 00:00:00
abstract：:Normal aging is characterized by brain glucose metabolism decline predominantly in the prefrontal cortex. The goal of the present study was to assess whether this change was associated with age-related alteration of white matter (WM) structural integrity and/or functional connectivity. FDG-PET data from 40 young and 5...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2013.03.009
更新日期：2013-08-01 00:00:00
abstract：:Recent work has shown a dramatic contrast between GM and WM in gradient echo phase images at high field (7 T). Although this contrast is key to the exploitation of phase in imaging normal and pathological tissue, its origin remains contentious. Several sources for this contrast have been considered including iron cont...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2009.12.052
更新日期：2010-04-01 00:00:00
abstract：:We determined the reproducibility of both the direction and the effect size of the word frequency effect (WFE) as it relates to associative semantic judgments. Sixteen volunteers were scanned twice. At the group level of analysis, signal change and voxel counting could both reproducibly detect the existence of a WFE. ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/s1053-8119(02)00019-8
更新日期：2003-02-01 00:00:00
abstract：:In this study we combined event-related fMRI with a parametric manipulation of the go nogo paradigm to examine the effect of preceding context on inhibitory processes. Nogo trials were preceded by either 1, 3, or 5 go trials and then compared to one another. Two distinct patterns of activation were associated with beh...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1006/nimg.2002.1074
更新日期：2002-06-01 00:00:00
abstract：:Because understanding neural vulnerability factors that predict future weight gain may guide the design of more effective obesity prevention programs and treatments, we tested whether neural response to palatable food tastes and images predicted future weight gain. We recruited 135 initially healthy weight adolescents...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2018.08.035
更新日期：2018-12-01 00:00:00
abstract：:Synchronization is a collective mechanism by which oscillatory networks achieve their functions. Factors driving synchronization include the network's topological and dynamical properties. However, how these factors drive the emergence of synchronization in the presence of potentially disruptive external inputs like s...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2021.117738
更新日期：2021-01-14 00:00:00
abstract：:Medical imaging has shown that, during early development, the brain undergoes more changes in size, shape and appearance than at any other time in life. A better understanding of brain development requires a spatio-temporal atlas that characterizes the dynamic changes during this period. In this paper we present an ap...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2011.09.062
更新日期：2012-02-01 00:00:00
abstract：:Depression is one of the leading causes of disability worldwide. Immense heterogeneity in symptoms of depression causes difficulty in diagnosis, and to date, there are no established biomarkers or imaging methods to examine depression. Unpredictable chronic mild stress (CMS) induced anhedonia is considered to be a rea...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2016.07.001
更新日期：2016-11-15 00:00:00
abstract：:Normal brain development depends on early sensory experience. Behavioral consequences of brain maturation in the absence of sensory input early in life are well documented. For example, experiments with mature, neonatally deaf human or animal subjects have revealed improved peripheral visual motion detection and spati...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2017.10.002
更新日期：2018-01-15 00:00:00
abstract：:Characterizing demyelination/degeneration of spinal pathways in traumatic spinal cord injured (SCI) patients is crucial for assessing the prognosis of functional rehabilitation. Novel techniques based on diffusion-weighted (DW) magnetic resonance imaging (MRI) and magnetization transfer (MT) imaging provide sensitive ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2010.11.089
更新日期：2011-04-01 00:00:00
abstract：:The discrimination of voice-onset time, an acoustic-phonetic cue to voicing in stop consonants, was investigated to explore the neural systems underlying the perception of a rapid temporal speech parameter. Pairs of synthetic stimuli taken from a [da] to [ta] continuum varying in voice-onset time (VOT) were presented ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2007.10.064
更新日期：2008-03-01 00:00:00
abstract：:There are now a number of non-invasive methods to image human brain function in-vivo. However, the accuracy of these images remains unknown and can currently only be estimated through the use of invasive recordings to generate a functional ground truth. Neuronal activity follows grey matter structure and accurate esti...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2014.02.033
更新日期：2014-07-01 00:00:00
abstract：:An influential framework suggests that the central nucleus of the amygdala (CeA) is involved in phasic responses to threat, while the bed nucleus of the stria terminalis (BNST) mediates sustained anxiety. However, this model has been questioned, proposing that the role of the BNST is not limited to sustained threat co...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2017.10.054
更新日期：2018-02-01 00:00:00
abstract：:Although the parietal cortex is not conventionally associated with memory, a large number of recent fMRI studies have suggested that that the parietal cortex may play a role in recognition memory. Activity in the lateral parietal cortex is correlated with the subjective impression that an item is old. It has therefore...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2010.11.066
更新日期：2011-03-15 00:00:00
abstract：:We survey the recent activities of the Odyssée Laboratory in the area of the application of mathematics to the design of models for studying brain anatomy and function. We start with the problem of reconstructing sources in MEG and EEG, and discuss the variational approach we have developed for solving these inverse p...
journal_title：NeuroImage
pub_type： 杂志文章,评审
doi：10.1016/j.neuroimage.2004.07.015
更新日期：2004-01-01 00:00:00
abstract：:Temporal lobe epilepsy with hippocampus sclerosis (HS) is the most frequent focal epilepsy and often refractory to anticonvulsant therapy. Secondary structural damage has been reported in several studies of temporal lobe epilepsy and unilateral hippocampal sclerosis. Applying diffusion tensor imaging (DTI) we investig...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2009.03.013
更新日期：2009-07-01 00:00:00
abstract：:Being in control of one's emotions is not only desirable in many everyday situations but is also a great challenge in a variety of mental disorders. Successful intentional emotion regulation is related to down-regulation of amygdala activity. Training mental interventions supported by neurofeedback of one's own amygda...
journal_title：NeuroImage
pub_type： 临床试验,杂志文章
doi：10.1016/j.neuroimage.2018.09.068
更新日期：2019-01-01 00:00:00
abstract：:Understanding the neuropathological underpinnings of mental disorders such as schizophrenia, major depression, and bipolar disorder is an essential step towards the development of targeted treatments. Diffusion MRI studies utilizing the diffusion tensor imaging (DTI) model have been extremely successful to date in ide...
journal_title：NeuroImage
pub_type： 杂志文章,评审
doi：10.1016/j.neuroimage.2018.04.051
更新日期：2018-11-15 00:00:00
abstract：:Model-based analysis methods for fMRI data assume a priori knowledge of the time course of the hemodynamic response (HR) in reaction to experimental stimuli or events. This knowledge is incorporated into the hemodynamic response function (HRF), which is a common model of the HR. Although it is already known that the H...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2006.06.003
更新日期：2006-09-01 00:00:00
abstract：AIMS:Using functional magnetic resonance imaging (fMRI) we investigated the cortical and subcortical representations during bladder filling and the effect of simultaneous stimulation of the dorsal clitoral nerve on these cortical and subcortical structures. METHODS:After approval of the local ethics committee, 8 healt...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2008.03.006
更新日期：2008-07-01 00:00:00
abstract：:ConnectomeDB is a database for housing and disseminating data about human brain structure, function, and connectivity, along with associated behavioral and demographic data. It is the main archive and dissemination platform for data collected under the WU-Minn consortium Human Connectome Project. Additional connectome...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2015.04.046
更新日期：2016-01-01 00:00:00
abstract：:Borderline personality disorder (BPD) is a severe psychiatric condition of undetermined brain underpinnings, which involves profound emotion regulation deficits and interpersonal impairment. To elucidate biopsychological markers of the disorder, we performed two studies: i.) assessing empathy and social cognition and ...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2011.05.005
更新日期：2011-07-15 00:00:00
abstract：:To investigate cortical auditory and motor coupling in professional musicians, we compared the functional magnetic resonance imaging (fMRI) activity of seven pianists to seven non-musicians utilizing a passive task paradigm established in a previous learning study. The tasks involved either passively listening to shor...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2005.10.044
更新日期：2006-04-15 00:00:00
abstract：:In the first year of life, infants' speech perception attunes to their native language. While the behavioral changes associated with native language attunement are fairly well mapped, the underlying mechanisms and neural processes are still only poorly understood. Using fNIRS and eye tracking, the current study invest...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2016.02.061
更新日期：2016-06-01 00:00:00
abstract：:Statistical parametric mapping (SPM) is currently the most widely used method for analysis of functional activation images. This paper reports a quantitative evaluation of the sensitivity and accuracy of SPM, using a realistic simulator of PET image formation, which accounted for the main physical processes involved i...
journal_title：NeuroImage
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1006/nimg.2000.0655
更新日期：2001-01-01 00:00:00
abstract：:Voxel-Based Morphometry (VBM) identifies differences in grey matter brain structure in patients with schizophrenia relative to healthy controls, with particularly prominent differences found in patients with the more severe, adolescent-onset form of the disease. However, as VBM is sensitive to a combination of changes...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2008.08.013
更新日期：2008-12-01 00:00:00
abstract：:Recent models of visual recognition have suggested that perceptual analysis may start with a parallel extraction of different spatial frequencies (SF), using a preferential coarse-to-fine (low-to-high SF) sequence of processing. A rapid extraction of low spatial frequency (LSF) information may thus provide an initial ...
journal_title：NeuroImage
pub_type： 临床试验,杂志文章
doi：10.1016/j.neuroimage.2005.06.006
更新日期：2005-11-01 00:00:00
abstract：:Interrupting a continuous noxious heat by a greater noxious heat causes rapid and disproportionate pain reduction when the original noxious heat returns. This reduction in pain experience, known as offset analgesia, is believed to be the consequence of active descending inhibitory control of pain originating in the pe...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2009.04.032
更新日期：2009-09-01 00:00:00
abstract：:Ageing generally leads to impairments in cognitive function and the ability to execute and learn new movements. While the causes of these impairments are often multi-factorial, integrity of the cerebellum in an elderly population is an important predictive factor of both motor function and cognitive function. A simila...
journal_title：NeuroImage
pub_type： 杂志文章
doi：10.1016/j.neuroimage.2015.03.084
更新日期：2015-08-01 00:00:00
