Abstract：
:Pediatric cancers often have specific molecular fingerprints making them primary candidates for the development of targeted imaging techniques. Tumor-targeted tracers have the potential to substantially advance the sensitivity and specificity of imaging techniques by improving tumor detection and characterization. This article reviews various approaches to target tumors via specific tumor antigens, tumor cell surface receptors and specific surface receptors of the endothelial cells of the tumor vessels. These new applied molecular imaging techniques are expected to improve our knowledge of the biology of pediatric cancers and, ultimately, to help in the development of tailored diagnoses and therapies, which may ultimately lead to better individual long-term outcomes.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Daldrup-Link HE,Hawkins RA,Meier R,Goldsby RE,Artemov Ddoi
10.1007/s00247-008-0878-xsubject
Has Abstractpub_date
2008-11-01 00:00:00pages
1154-61issue
11eissn
0301-0449issn
1432-1998journal_volume
38pub_type
杂志文章,评审abstract：:We report an 18-year-old boy with occipital horn syndrome who developed aneurysms of the splenic and hepatic arteries. Occipital horn syndrome, also called X-linked cutis laxa or Ehlers-Danlos syndrome (EDS) type IX, is characterised by a skeletal dysplasia which includes occipital horns, broad clavicles, deformed rad...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s002470050526
更新日期：1999-01-01 00:00:00
abstract：: ...
journal_title：Pediatric radiology
pub_type： 评论,信件
doi：10.1007/s00247-018-4234-5
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:While several studies have investigated the dose from scattered radiation from X-ray procedures in a pediatric nursery, they examined scatter from chest procedures only, or the types of examination were not specified. OBJECTIVE:The aim of this study was to collect scatter and transmission data from several ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-003-0999-1
更新日期：2003-10-01 00:00:00
abstract：:The detailed radiographic features of triploidy, a fatal congenital disorder with 69 chromosomes, have not previously been reported. Radiographs of ten liveborn infants with chromosomally confirmed triploidy showed six findings highly suggestive of this diagnosis: harlequin orbits, small anterior fontanelle, gracile r...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02386842
更新日期：1989-01-01 00:00:00
abstract：:Gastrointestinal tract duplications are relatively uncommon in the paediatric age group. This is a report of an infant who had a tubular duplication of the jejunum which extended into the thoracic cavity via the aortic hiatus of the diaphragm. ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02015363
更新日期：1992-01-01 00:00:00
abstract：:Eighty children suffering from pulmonary and/or hepatic echinococcosis are reported. The epidemiological and parasitological aspects are reviewed, and the importance of the radiological signs and differential diagnosis are emphasized. ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF00975441
更新日期：1978-09-26 00:00:00
abstract：BACKGROUND:Anteriorly displaced anus is an anomaly that is debated with regard to its nomenclature, diagnosis and management. OBJECTIVE:To describe MRI anatomy of the anal canal in children with anteriorly displaced anus and its impact on the process of defecation. MATERIALS AND METHODS:We prospectively examined ten ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-014-2897-0
更新日期：2014-07-01 00:00:00
abstract：:Technical and clinical aspects of esophageal transit scintigraphy in pediatric patients are reviewed via several illustrative cases that highlight its utility in evaluating primary and secondary esophageal motility disorders. ...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-018-4301-y
更新日期：2019-05-01 00:00:00
abstract：:A case of the Hajdu-Cheney syndrome in a 15 year old boy is described. The manifestations were: 1. isiopathic progressive acro-osteotions; 2. mutiple cranio-skeletal abnormalities; and 3. polycystic kidneys complicated by a rapidly progressive glomerulonephritis. ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF00973535
更新日期：1977-09-01 00:00:00
abstract：BACKGROUND:A hernia is due to a defect in the diaphragm. An eventration is due to a thinned diaphragm with no central muscle. Distinguishing right diaphragmatic hernia from eventration on chest radiographs can be challenging if no bowel loops are herniated above the diaphragm. Experience is limited with postnatal ultra...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-019-04417-1
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND:Head computed tomography (CT) is the current standard of care for evaluating infants at high risk of abusive head trauma. OBJECTIVE:To both assess the feasibility of using a previously developed magnetic resonance imaging (MRI) brain injury screen (MRBRscreen) in the acute care setting in place of head CT t...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-019-04506-1
更新日期：2020-01-01 00:00:00
abstract：:Kidney length (KL), renal area and renal parenchymal area were measured on i.v. urograms of 255 children without apparent kidney disease age 0 to 14 years. These parameters were compared with age, body height, body surface area and the distance between the 1st and 4th lumbar vertebral body. In addition, renal parenchy...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF01464310
更新日期：1980-04-01 00:00:00
abstract：:Chylous reflux is a manifestation of primary or secondary lymphatic obstruction. Primary lymphatic obstruction is defined as lymphangiectasia and incompetency of lymphatic valves without an underlying cause. Lymphangiectasia resulting from trauma, neoplasm, irradiation, or inflammation characterizes secondary lymphati...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s002470050219
更新日期：1997-09-01 00:00:00
abstract：:We report a case of a child with D-transposition of the great arteries treated with prostaglandin E1 (PGE1) who subsequently developed extensive brown fat necrosis. To the best of our knowledge, no previous association among congenital heart disease, PGE1, and brown fat necrosis has been reported. ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s002470050536
更新日期：1999-01-01 00:00:00
abstract：:Part 1 of this series of two articles describes conventional and advanced MRI techniques that are useful for evaluating brainstem pathologies. In addition, it provides a review of the embryology, normal progression of myelination, and clinically and radiologically salient imaging anatomy of the normal brainstem. Final...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-020-04954-0
更新日期：2021-02-01 00:00:00
abstract：:We present two cases of granulocytic sarcoma of the cervical lymph nodes with central necrosis as an initial manifestation of childhood leukaemia, focusing on the imaging features. Recognition of the CT and MR imaging findings of granulocytic sarcoma involving the cervical lymph nodes assists the differential diagnosi...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-008-0748-6
更新日期：2008-06-01 00:00:00
abstract：:The safety and diagnostic efficacy of the new non-ionic, monomeric contrast medium iopentol (Imagopaque) were evaluated and compared with those of the ionic medium metrizoate (Isopaque), in urography in children in a randomized, double-blind, parallel study. The trial comprised 59 children aged from 3 months to 8 year...
journal_title：Pediatric radiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF02020165
更新日期：1994-01-01 00:00:00
abstract：:An evaluation of the Siemens Digiscan has been undertaken to determine whether digital luminescence radiography (DLR) could replace conventional radiography in the examination of the neonate and young infant. Whilst the overall image quality of the digital radiograph was consistently higher than for conventional radio...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02011600
更新日期：1992-01-01 00:00:00
abstract：:Neonatal cerebral MR imaging is a sensitive technique for evaluating brain injury in the term and preterm infant. In term encephalopathic infants, MR imaging reliably detects not only the pattern of brain injury but might also provide clues about the timing of injury. In premature infants, MR imaging has surpassed US ...
journal_title：Pediatric radiology
pub_type： 杂志文章,实务指引
doi：10.1007/s00247-007-0705-9
更新日期：2008-03-01 00:00:00
abstract：:A case of pyelocalyceal diverticula in a patient with the Beckwith-Wiedemann syndrome is presented. The abnormalities were first identified on screening ultrasound and confirmed at excretory urography. The diverticula in this syndrome are likely secondary to hereditary embryopathy of the kidneys. ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02386605
更新日期：1987-01-01 00:00:00
abstract：:We present a case of neonatal acute gastric outlet obstruction related to prostaglandin-induced gastric foveolar hyperplasia, which developed following infusion of prostaglandin E1 (PGE1) for treatment of hypoplastic left heart syndrome. Abdominal distension occurred after administration of PGE1 in a cumulative dose o...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s002470050064
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND:Emergent MRI is now a viable alternative to CT for evaluating appendicitis while avoiding the detrimental effects of ionizing radiation. However, primary employment of MRI in the setting of clinically suspected pediatric appendicitis has remained significantly underutilized. OBJECTIVE:To describe our instit...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-012-2412-4
更新日期：2012-09-01 00:00:00
abstract：BACKGROUND:Preterm and low-birth-weight infants have an increased risk of sensorineural hearing loss. Brainstem auditory-evoked potentials (BAEP) are an effective method to detect subtle deficits in impulse conduction in the auditory pathway. Abnormalities on diffusion tensor imaging (DTI) have been shown to be associa...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-009-1278-6
更新日期：2009-08-01 00:00:00
abstract：:We retrospectively reviewed the imaging and surgical findings in 17 patients with duodenal atresia to determine (a) the frequency of coexistent malrotation in patients with duodenal atresia and (b) the reliability of the upper gastrointestinal barium study (UGI) in differentiating malrotation from postoperative deform...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02012180
更新日期：1994-01-01 00:00:00
abstract：:The need for X-ray investigations of the urinary tract at the time of the first proven urinary infection, even in older girls, is stressed. This policy is the best way to detect chronic pyelonephritis and congenital anomalies of the urinary tract and provide timely and appropriate treatment. These conclusions are supp...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF00972109
更新日期：1977-10-28 00:00:00
abstract：BACKGROUND:It has been suggested that the pelvis should not be habitually included on abdominal CT examinations, but the potential benefit of such a practice in childhood abdominal malignancies is unknown. OBJECTIVE:To estimate the yield and potential diagnostic benefit of abnormal findings on CT of the pelvis in chil...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-005-0053-6
更新日期：2006-03-01 00:00:00
abstract：:This multicenter collaborative study was undertaken to review the types and complications of femoral neck fractures in children. It is a retrospective clinical and radiological review of 108 femoral neck fractures. Cases originated from four different pediatric hospitals. All the patients had plain radiographs. Fractu...
journal_title：Pediatric radiology
pub_type： 杂志文章,多中心研究
doi：10.1007/BF02012436
更新日期：1993-01-01 00:00:00
abstract：:Abdominal aortic injury after blunt trauma is rare in the pediatric population. There have been fewer than 20 reported cases in the literature since 1960, and most were the result of motor vehicle collisions. We report the case of a 16-month-old boy who is the youngest reported patient to sustain this type of injury. ...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-009-1224-7
更新日期：2009-07-01 00:00:00
abstract：:A retrospective analysis of radiologically determined individual renal function was performed in five boys who presented in the neonatal period with posterior urethral valves, vesicoureteral reflux and documented urinoma formation. Renal function was evaluated with scintigraphy. There was reflux in eight of ten ureter...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02011386
更新日期：1990-01-01 00:00:00
abstract：:Polyostotic bone and bone marrow lesions in children may be due to various disorders. Radiographically, lytic lesions may become apparent after loss of more than 50% of the bone mineral content. Scintigraphy requires osteoblastic activity and is not specific. MRI may significantly contribute to the correct diagnosis a...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-016-3737-1
更新日期：2017-03-01 00:00:00
