当前位置： SCI文献检索 > Journal of Hospital Medicine期刊下所有文献 > Use of dexmedetomidine for sedation of children hospitalized in the intensive care unit.

Use of dexmedetomidine for sedation of children hospitalized in the intensive care unit.

Abstract：

BACKGROUND:Dexmedetomidine is a potentially useful sedative for hospitalized children, but there is little published data regarding its safety, dosage, or efficacy. OBJECTIVE:To report our experience with dexmedetomidine for the sedation of hospitalized children. DESIGN:Retrospective case series. SETTING:Pediatric ICU of a university-affiliated children's hospital. PATIENTS:We retrospectively examined data from the medical records of all children who received dexmedetomidine for sedation between December 2003 and October 2005. INTERVENTION:None. RESULTS:Dexmedetomidine was administered 74 times to 60 children (median age 1.5 years, range 0.1-17.2 years). The most common indications for ICU admission were respiratory distress/failure (53%), status-postcorrective cardiac surgery (19%), and other postoperative patients (18%). In 53% of cases dexmedetomidine was used to supplement ongoing sedation judged inadequate and in 41% of cases it was used as a bridge to extubation while other sedatives were weaned or discontinued. Among all the children, the median dose to maintain adequate sedation was 0.7 microg/kg per hour (range 0.2-2.5 microg/kg per hour), with a median duration of therapy of 23 hours (range 3-451 hours). Most children (80%) experienced no adverse effects from the sedation, with hypotension (9%), hypertension (8%), and bradycardia (3%) the most common adverse events. For 93% of children who experienced a side effect, it resolved either without treatment or by withholding the infusion. CONCLUSIONS:In this cohort of children hospitalized in the ICU, dexmedetomidine appeared to be effective and to have few adverse effects. Dexmedetomidine may have a potentially useful role to play in sedating hospitalized children.

journal_name

J Hosp Med

journal_title

Journal of hospital medicine

authors

Carroll CL,Krieger D,Campbell M,Fisher DG,Comeau LL,Zucker AR

doi

10.1002/jhm.282

subject

Has Abstract

pub_date

2008-03-01 00:00:00

pages

142-7

issue

2

eissn

1553-5592

issn

1553-5606

journal_volume

3

pub_type

杂志文章

相关文献

Journal of Hospital Medicine文献大全
  • Development of a pediatric hospitalist sedation service: training and implementation.

    abstract：OBJECTIVE:There is growing demand for safe and effective procedural sedation in pediatric facilities nationally. Currently, these needs are being met by a variety of providers and sedation techniques, including anesthesiologists, pediatric intensivists, emergency medicine physicians, and pediatric hospitalists. There i...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.1002/jhm.979

    authors： Turmelle M,Moscoso LM,Hamlin KP,Daud YN,Carlson DW

    更新日期：2012-04-01 00:00:00

  • Influence of house-staff experience on teaching-hospital mortality: the "July phenomenon" revisited.

    abstract：BACKGROUND:The "July phenomenon" refers to a purported worsening of outcomes in teaching-hospital patients with the arrival of new, inexperienced house-staff. Previous quantitative studies of new house-staff and increased mortality have been limited primarily by a focused patient population and the use of limited data ...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.1002/jhm.917

    authors： van Walraven C,Jennings A,Wong J,Forster AJ

    更新日期：2011-09-01 00:00:00

  • How complete is the evidence for thromboembolism prophylaxis in general medicine patients? A meta-analysis of randomized controlled trials.

    abstract：OBJECTIVES:Guidelines recommend pharmacologic prophylaxis for hospitalized medical patients at increased risk of thromboembolism. Despite recommendations, multiple studies demonstrate underutilization. Factors contributing to underutilization include uncertainty that prophylaxis reduces clinically relevant events, as w...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章,meta分析

    doi：10.1002/jhm.450

    authors： Bump GM,Dandu M,Kaufman SR,Shojania KG,Flanders SA

    更新日期：2009-05-01 00:00:00

  • Risk factors for unplanned transfer to intensive care within 24 hours of admission from the emergency department in an integrated healthcare system.

    abstract：BACKGROUND:Emergency department (ED) ward admissions subsequently transferred to the intensive care unit (ICU) within 24 hours have higher mortality than direct ICU admissions. DESIGN, SETTING, PATIENTS:Describe risk factors for unplanned ICU transfer within 24 hours of ward arrival from the ED. METHODS:Evaluation of...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.1002/jhm.1979

    authors： Delgado MK,Liu V,Pines JM,Kipnis P,Gardner MN,Escobar GJ

    更新日期：2013-01-01 00:00:00

  • When Reducing Low-Value Care in Hospital Medicine Saves Money, Who Benefits ?

    abstract：:One emerging policy solution for deterring low-value care is to financially penalize physicians who prescribe it. However, physicians' willingness to support such policies may depend on whether they perceive that benefits accrue to patients or to insurers and hospitals. We surveyed physicians practicing hospital medic...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.12788/jhm.2878

    authors： Liao JM,Navathe AS,Schapira MM,Weissman A,Mitra N,Asch DA

    更新日期：2018-01-01 00:00:00

  • Care of hospitalized older patients: opportunities for hospital-based physicians.

    abstract：BACKGROUND:Half of patients admitted to hospital for reasons unrelated to childbirth are age 65 years or older. Nonetheless, few hospital-based physicians have received training in geriatric medicine, and few geriatricians practice in the hospital. This paper describes the state of the science of hospital care for olde...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章,评审

    doi：10.1002/jhm.11

    authors： Landefeld CS

    更新日期：2006-01-01 00:00:00

  • Use of Short Peripheral Intravenous Catheters: Characteristics, Management, and Outcomes Worldwide.

    abstract：BACKGROUND:Peripheral intravenous catheter (PIVC) use in health care is common worldwide. Failure of PIVCs is also common, resulting in premature removal and replacement. OBJECTIVE:To investigate the characteristics, management practices, and outcomes of PIVCs internationally. DESIGN: SETTING/PATIENTS:Cross-sectiona...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.12788/jhm.3039

    authors： Alexandrou E,Ray-Barruel G,Carr PJ,Frost SA,Inwood S,Higgins N,Lin F,Alberto L,Mermel L,Rickard CM,OMG Study Group.

    更新日期：2018-05-30 00:00:00

  • Hospital Medicine Has a Specialty Code. Is the Memo Still in the Mail?

    abstract：:The Centers for Medicare and Medicaid Services awarded Hospital Medicine a Medicare specialty code, "C6", in 2016. We examined the early uptake of C6 code using the 2017 Medicare Part B utilization data. We also compared the actual C6 specialty code usage against estimated rates of overall hospitalist billing using th...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.12788/jhm.3303

    authors： Flansbaum B,Leykum L,Lapps J

    更新日期：2020-02-01 00:00:00

  • Nephrotoxin-Related Acute Kidney Injury and Predicting High-Risk Medication Combinations in the Hospitalized Child.

    abstract：BACKGROUND:In the hospitalized patient, nephrotoxin exposure is one potentially modifiable risk factor for acute kidney injury (AKI). Clinical decision support based on nephrotoxin ordering was developed at our hospital to assist inpatient providers with the prevention or mitigation of nephrotoxin-related AKI. The init...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.12788/jhm.3196

    authors： Yonekawa KE,Zhou C,Haaland WL,Wright DR

    更新日期：2019-08-01 00:00:00

  • Opportunities and Challenges for Improving the Patient Experience in the Acute and Postacute Care Setting Using Patient Portals: The Patient's Perspective.

    abstract：:Efforts to improve the patient experience are increasingly focusing on engaging patients and their "care partners" by using patient portals. The Acute Care Patient Portal Task Force was supported by the Gordon and Betty Moore Foundation to convene a national meeting of an interdisciplinary group of stakeholders, inclu...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.12788/jhm.2860

    authors： Dalal AK,Bates DW,Collins S

    更新日期：2017-12-01 00:00:00

  • Sensitivity of superficial cultures in lower extremity wounds.

    abstract：BACKGROUND:Superficial wound cultures are routinely used to guide therapy, despite a lack of clear supporting evidence. PURPOSE:To conduct a systematic review of the correlation between superficial wound cultures and the etiology of skin and soft tissue infections. DATA SOURCES:Medline, EMBASE, CINAHL, Scopus. STUDY...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章,meta分析,评审

    doi：10.1002/jhm.688

    authors： Chakraborti C,Le C,Yanofsky A

    更新日期：2010-09-01 00:00:00

  • The impact of individual variation analysis on myocardial perfusion imaging utilization within a hospitalist group.

    abstract：BACKGROUND:Increased recognition of ionizing radiation risks has placed an emphasis on the appropriate use of myocardial perfusion imaging (MPI). Hospitalists frequently order MPI in the evaluation of chest pain and are thus at the forefront of its inpatient utilization. METHODS:We collected baseline figures for a gro...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.1002/jhm.2288

    authors： Bohossian HB,Park AW,Holcroft C

    更新日期：2015-03-01 00:00:00

  • Health information exchange systems and length of stay in readmissions to a different hospital.

    abstract：BACKGROUND:Readmission to a different hospital than the original discharge hospital may result in breakdowns in continuity of care. In different-hospital readmissions (DHRs), continuity can be maintained when hospitals are connected through health information exchange (HIE) systems. OBJECTIVE:To examine whether length...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.1002/jhm.2535

    authors： Flaks-Manov N,Shadmi E,Hoshen M,Balicer RD

    更新日期：2016-06-01 00:00:00

  • Postdischarge problems identified by telephone calls to an advice line.

    abstract：BACKGROUND:Problems experienced after hospital discharge can result in rehospitalizations and unscheduled urgent and emergent care. OBJECTIVE:To identify opportunities for improving discharge processes by examining calls to an advice line (AL). DESIGN:Prospective cohort. SETTING:A 500-bed, university-affiliated hosp...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.1002/jhm.2252

    authors： Stella SA,Allyn R,Keniston A,Johnston LB,Burden M,Bogdan GM,Savoie C,Albert RK

    更新日期：2014-11-01 00:00:00

  • Job characteristics, satisfaction, and burnout across hospitalist practice models.

    abstract：BACKGROUND:Nearly two-thirds of hospitals in the United States are served by hospitalist physicians. How hospitalist work patterns and job satisfaction vary across various practice models is unknown. METHODS:We administered the Hospitalist Worklife Survey to a randomized stratified sample of 3105 potential hospitalist...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1002/jhm.1907

    authors： Hinami K,Whelan CT,Miller JA,Wolosin RJ,Wetterneck TB,Society of Hospital Medicine Career Satisfaction Task Force.

    更新日期：2012-05-01 00:00:00

  • State of Research in Adult Hospital Medicine: Results of a National Survey.

    abstract：BACKGROUND:Little is known about the state of research in academic hospital medicine (HM) despite the substantial growth of this specialty. METHODS:We used the Society of Hospital Medicine (SHM) membership database to identify research programs and their leadership. In addition, the members of the SHM Research Committ...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.12788/jhm.3136

    authors： Chopra V,Burden M,Jones CD,Mueller S,Gupta V,Ahuja N,Sigmund A,Eid SM,Society of Hospital Medicine Research Committee.

    更新日期：2019-04-01 00:00:00

  • Optimizing prevention of hospital-acquired venous thromboembolism (VTE): prospective validation of a VTE risk assessment model.

    abstract：BACKGROUND:Hospital-acquired (HA) venous thromboembolism (VTE) is a common source of morbidity/mortality. Prophylactic measures are underutilized. Available risk assessment models/protocols are not prospectively validated. OBJECTIVES:Improve VTE prophylaxis, reduce HA VTE, and prospectively validate a VTE risk-assessm...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.1002/jhm.562

    authors： Maynard GA,Morris TA,Jenkins IH,Stone S,Lee J,Renvall M,Fink E,Schoenhaus R

    更新日期：2010-01-01 00:00:00

  • Hospitalist and Internal Medicine Leaders' Perspectives of Early Discharge Challenges at Academic Medical Centers.

    abstract：:Improving early discharges may improve patient flow and increase hospital capacity. We conducted a national survey of academic medical centers addressing the prevalence, importance, and effectiveness of early-discharge initiatives. We assembled a list of hospitalist and general internal medicine leaders at 115 US-base...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.12788/jhm.2885

    authors： Patel H,Fang MC,Mourad M,Green A,Wachter RM,Murphy RD,Harrison JD

    更新日期：2018-06-01 00:00:00

  • Screening for depression in hospitalized medical patients.

    abstract：:Depression among hospitalized patients is often unrecognized, undiagnosed, and therefore untreated. Little is known about the feasibility of screening for depression during hospitalization, or whether depression is associated with poorer outcomes, longer hospital stays, and higher readmission rates. We searched PubMed...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章,评审

    doi：10.12788/jhm.2693

    authors： IsHak WW,Collison K,Danovitch I,Shek L,Kharazi P,Kim T,Jaffer KY,Naghdechi L,Lopez E,Nuckols T

    更新日期：2017-02-01 00:00:00

  • Next Steps in Improving Healthcare Value: AHRQ Evidence-based Practice Center Program-Applying the Knowledge to Practice to Data Cycle to Strengthen the Value of Patient Care.

    abstract：:For more than 20 years, the Agency for Healthcare Research and Quality (AHRQ) Evidence-based Practice Center (EPC) Program has been identifying and synthesizing evidence to inform evidence-based healthcare. Recognizing that many healthcare settings continue to face challenges in disseminating and implementing evidence...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.12788/jhm.3157

    authors： Borsky AE,Flores EJ,Berliner E,Chang C,Umscheid CA,Chang SM

    更新日期：2019-05-01 00:00:00

  • Experiences of older adults in a group physiotherapy program at a rehabilitation hospital: A qualitative study.

    abstract：:Physiotherapy delivered in a group setting has been shown to be effective in a variety of populations. However, little is known about the attitudes of older adults toward participating in group physiotherapy. The objectives of this study were to explore older inpatients' perceptions and experiences of group physiother...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章,随机对照试验

    doi：10.1002/jhm.2550

    authors： Raymond MJ,Burge AT,Soh SE,Jeffs KJ,Winter A,Holland AE

    更新日期：2016-05-01 00:00:00

  • National Acute Medicine Programme--improving the care of all medical patients in Ireland.

    abstract：BACKGROUND:The National Acute Medicine Programme (NAMP) was established to address the unsatisfactory management of acutely ill medical patients in Ireland. It aimed to improve quality of care and patient safety, streamline access to healthcare, and reduce cost through efficiency gains. METHOD:A model of care was deve...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.1002/jhm.2443

    authors： O'Reilly O,Cianci F,Casey A,Croke E,Conroy C,Keown AM,Leane G,Kearns B,O'Neill S,Courtney G

    更新日期：2015-12-01 00:00:00

  • Hospital Privileging Practices for Bedside Procedures: A Survey of Hospitalist Experts.

    abstract：:Many hospitalists are routinely granted hospital privileges to perform invasive bedside procedures, but criteria for privileging are not well described. We conducted a survey of 21 hospitalist procedure experts from the Society of Hospital Medicine Point-of-Care Ultrasound Task Force to better understand current privi...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.12788/jhm.2837

    authors： Jensen TP,Soni NJ,Tierney DM,Lucas BP

    更新日期：2017-10-01 00:00:00

  • Development of Hospitalization Resource Intensity Scores for Kids (H-RISK) and Comparison across Pediatric Populations.

    abstract：BACKGROUND:In the Medicare population, measures of relative severity of illness (SOI) for hospitalized patents have been used in prospective payment models. Similar measures for pediatric populations have not been fully developed. OBJECTIVE:To develop hospitalization resource intensity scores for kids (H-RISK) using p...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.12788/jhm.2948

    authors： Richardson T,Rodean J,Harris M,Berry J,Gay JC,Hall M

    更新日期：2018-09-01 00:00:00

  • Frequently Hospitalized Patients' Perceptions of Factors Contributing to High Hospital Use.

    abstract：BACKGROUND:A small proportion of patients accounts for a large proportion of hospitalizations. OBJECTIVE:To obtain patients' perspectives of factors associated with the onset and continuation of high hospital use. DESIGN:Qualitative research study where a research coordinator conducted one-on-one semi-structured inte...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.12788/jhm.3175

    authors： O'Leary KJ,Chapman MM,Foster S,O'Hara L,Henschen BL,Cameron KA

    更新日期：2019-03-20 00:00:00

  • Lean-Based Redesign of Multidisciplinary Rounds on General Medicine Service.

    abstract：BACKGROUND:Multidisciplinary rounds (MDR) facilitate timely communication amongst the care team and with patients. We used Lean techniques to redesign MDR on the teaching general medicine service. OBJECTIVE:To examine if our Lean-based new model of MDR was associated with change in the primary outcome of length of sta...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.12788/jhm.2908

    authors： Kane M,Rohatgi N,Heidenreich P,Thakur A,Winget M,Shum K,Hereford J,Shieh L,Lew T,Horn J,Chi J,Weinacker A,Seay-Morrison T,Ahuja N

    更新日期：2018-07-01 00:00:00

  • Medications associated with geriatric syndromes and their prevalence in older hospitalized adults discharged to skilled nursing facilities.

    abstract：BACKGROUND:More than half of the hospitalized older adults discharged to skilled nursing facilities (SNFs) have more than 3 geriatric syndromes. Pharmacotherapy may be contributing to geriatric syndromes in this population. OBJECTIVES:Develop a list of medications associated with geriatric syndromes and describe their...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.1002/jhm.2614

    authors： Saraf AA,Petersen AW,Simmons SF,Schnelle JF,Bell SP,Kripalani S,Myers AP,Mixon AS,Long EA,Jacobsen JM,Vasilevskis EE

    更新日期：2016-10-01 00:00:00

  • Hospitalists' ability to use hand-carried ultrasound for central venous pressure estimation after a brief training intervention: a pilot study.

    abstract：BACKGROUND:Access to hand-carried ultrasound technology for noncardiologists has increased significantly, yet development and evaluation of training programs are limited. OBJECTIVE:We studied a focused program to teach hospitalists image acquisition of inferior vena cava (IVC) diameter and IVC collapsibility index wit...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.1002/jhm.2103

    authors： Martin LD,Ziegelstein RC,Howell EE,Martire C,Hellmann DB,Hirsch GA

    更新日期：2013-12-01 00:00:00

  • Why surgeons can say "no": exploring "unilateral withholding".

    abstract：OBJECTIVE:To explore why it is permissible for surgeons to "unilaterally withhold" surgery, whereas it is not commonplace (in the United States) to unilaterally withhold cardiopulmonary resuscitation (CPR) for clinical situations with similar degrees of uncertainty and prognosis. DATA SOURCES:The medical literature wa...

    journal_title：Journal of hospital medicine

    pub_type： 社论

    doi：10.1002/jhm.986

    authors： Manthous CA,Ivy M

    更新日期：2012-03-01 00:00:00

  • Pediatric hospitalists: training, current practice, and career goals.

    abstract：OBJECTIVE:To determine the range and frequency of experiences, clinical and nonclinical roles, training, work expectations, and career plans of practicing pediatric hospitalists. DESIGN:Mail survey study of a national sample of 530 pediatric hospitalists of whom 67% (N = 338) were from teaching hospitals, 71% (N = 374...

    journal_title：Journal of hospital medicine

    pub_type： 杂志文章

    doi：10.1002/jhm.458

    authors： Freed GL,Dunham KM,Research Advisory Committee of the American Board of Pediatrics.

    更新日期：2009-03-01 00:00:00