Abstract:
BACKGROUND:Endoscopic nasobiliary drainage (NBD) for the treatment of acute cholangitis is an accepted method. A recently developed ultrathin transnasal videoendoscope is minimally invasive, even for patients who are critically ill. OBJECTIVE:To evaluate the clinical efficacy and safety of 1-step NBD by transnasal videoendoscopy (TNE). DESIGN:Prospective case study. SETTING:This study was performed at Tokyo Medical University Hospital. PATIENTS:Twenty patients with acute cholangitis who had previously undergone an endoscopic sphincterotomy (ES); including 10 with bile-duct stones, 8 with pancreatic cancers, 1 with chronic pancreatitis, and 1 with benign biliary stricture, were enrolled in this study. An indwelling self-expandable metallic stent (SEMS) was placed in all patients with pancreatic cancers. INTERVENTION:All patients underwent NBD via front-viewing TNE. A 5F NBD catheter was placed into the bile duct. MAIN OUTCOME MEASUREMENT:The efficacy and safety of this technique. RESULTS:The transnasal insertion of TNE was feasible in all patients, and none had epistaxis. Abdominal pain, fever, and jaundice were improved at 24 hours after the procedure in the majority of patients. The mean procedural time was 18.1 minutes. One patient pulled out the NBD catheter. None of the patients died. TNE-NBD was achieved in 19 patients (95%). LIMITATIONS:Maneuverability of the TNE, limited to patients with a previous ES or the placement of an SEMS. CONCLUSIONS:NBD that uses TNE may be a useful and novel technique for the treatment of acute cholangitis in patients with previous ES.
journal_name
Gastrointest Endoscjournal_title
Gastrointestinal endoscopyauthors
Itoi T,Kawai T,Sofuni A,Itokawa F,Tsuchiya T,Kurihara T,Kusano C,Saito Y,Gotoda Tdoi
10.1016/j.gie.2007.11.050subject
Has Abstractpub_date
2008-07-01 00:00:00pages
84-90issue
1eissn
0016-5107issn
1097-6779pii
S0016-5107(07)03188-4journal_volume
68pub_type
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