Electrical effects of spin density wave quantization and magnetic domain walls in chromium.

abstract：:Patchwork homology observed between divergent members of polymorphic multigene families is thought to reflect evolution by short-tract gene conversion (nonreciprocal recombination), although this mechanism cannot usually be confirmed in higher organisms. In contrast to meiotic conversions observed in laboratory yeast ...

journal_title：Nature

authors： Wheeler CJ,Maloney D,Fogel S,Goodenow RS

更新日期：1990-09-13 00:00:00

abstract：:Multiple endocrine neoplasia type 1 (MEN-1) is a predisposition to hyperplasia of the parathyroid glands, and to hyperplasia or tumours of the anterior pituitary and the endocrine pancreas, and is inherited as an autosomal dominant trait. Here we map the MEN-1 locus to chromosome 11 by family studies, and demonstrate ...

journal_title：Nature

authors： Larsson C,Skogseid B,Oberg K,Nakamura Y,Nordenskjöld M

更新日期：1988-03-03 00:00:00

abstract：:Crystal structures of insulin have been determined in various distinct forms, the relevance of which to receptor recognition has long been the subject of speculation. Recently the crystal structure of an inactive insulin analogue has been determined and, surprisingly, found to have a conformation identical to native i...

journal_title：Nature

authors： Hua QX,Shoelson SE,Kochoyan M,Weiss MA

更新日期：1991-11-21 00:00:00

abstract：:Marine records of sediment oxygen isotope compositions show that the Earth's climate has gone through a succession of glacial and interglacial periods during the past million years. But the interpretation of the oxygen isotope records is complicated because both isotope storage in ice sheets and deep-water temperature...

journal_title：Nature

authors： Bintanja R,van de Wal RS,Oerlemans J

更新日期：2005-09-01 00:00:00

abstract：:Remodelling its shape, or morphogenesis, is a fundamental property of living tissue. It underlies much of embryonic development and numerous pathologies. Convergent extension (CE) of the axial mesoderm of vertebrates is an intensively studied model for morphogenetic processes that rely on cell rearrangement. It involv...

journal_title：Nature

authors： Ninomiya H,Elinson RP,Winklbauer R

更新日期：2004-07-15 00:00:00

abstract：:The nuclear bulge is a region with a radius of about 200 parsecs around the centre of the Milky Way. It contains stars with ages ranging from a few million years to over a billion years, yet its star-formation history and the triggering process for star formation remain to be resolved. Recently, episodic star formatio...

journal_title：Nature

authors： Matsunaga N,Kawadu T,Nishiyama S,Nagayama T,Kobayashi N,Tamura M,Bono G,Feast MW,Nagata T

更新日期：2011-08-24 00:00:00

abstract：:Topological insulators-materials that are insulating in the bulk but allow electrons to flow on their surface-are striking examples of materials in which topological invariants are manifested in robustness against perturbations such as defects and disorder1. Their most prominent feature is the emergence of edge states...

journal_title：Nature

authors： Klembt S,Harder TH,Egorov OA,Winkler K,Ge R,Bandres MA,Emmerling M,Worschech L,Liew TCH,Segev M,Schneider C,Höfling S

更新日期：2018-10-01 00:00:00

abstract：:Recent studies have shown that initial sensitization to airborne environmental allergens occurs typically in early childhood, but subsequent progression to persistent atopic asthma, which may not manifest for several years, is restricted to only a subset of atopics. The key to establishing the link between atopy and a...

journal_title：Nature

authors： Holt PG,Macaubas C,Stumbles PA,Sly PD

更新日期：1999-11-25 00:00:00

abstract：:The epidermal growth factor receptor (EGFR)-directed tyrosine kinase inhibitors (TKIs) gefitinib, erlotinib and afatinib are approved treatments for non-small cell lung cancers harbouring activating mutations in the EGFR kinase, but resistance arises rapidly, most frequently owing to the secondary T790M mutation withi...

journal_title：Nature

authors： Jia Y,Yun CH,Park E,Ercan D,Manuia M,Juarez J,Xu C,Rhee K,Chen T,Zhang H,Palakurthi S,Jang J,Lelais G,DiDonato M,Bursulaya B,Michellys PY,Epple R,Marsilje TH,McNeill M,Lu W,Harris J,Bender S,Wong KK,Jänne PA

更新日期：2016-06-02 00:00:00

abstract：:Comparative mapping, which compares the location of homologous genes in different species, is a powerful tool for studying genome evolution. Comparative maps suggest that rates of chromosomal change in mammals can vary from one to ten rearrangements per million years. On the basis of these rates we would expect 84 to ...

journal_title：Nature

authors： Burt DW,Bruley C,Dunn IC,Jones CT,Ramage A,Law AS,Morrice DR,Paton IR,Smith J,Windsor D,Sazanov A,Fries R,Waddington D

更新日期：1999-11-25 00:00:00

abstract：:The extent of allelic variation has been estimated at 46 structural gene loci within three major colonies of Swiss mice and between inbred derivative strains. The colonies have retained nearly the same amount and type of variation found in natural murine or human populations despite laboratory propagation for more tha...

journal_title：Nature

authors： Rice MC,O'Brien SJ

更新日期：1980-01-10 00:00:00

abstract：:There is increasing evidence for the process of sympatric speciation, in which reproductive isolation of species occurs without physical isolation. Theoretical models have focused on disruptive natural selection as the crucial pressure for splitting a species. Here we report the theoretical finding that sympatric spec...

journal_title：Nature

authors： Higashi M,Takimoto G,Yamamura N

更新日期：1999-12-02 00:00:00

abstract：:High-harmonic generation by focusing a femtosecond laser onto a gas is a well-known method of producing coherent extreme-ultraviolet (EUV) light. This nonlinear conversion process requires high pulse intensities, greater than 10(13) W cm(-2), which are not directly attainable using only the output power of a femtoseco...

journal_title：Nature

authors： Kim S,Jin J,Kim YJ,Park IY,Kim Y,Kim SW

更新日期：2008-06-05 00:00:00

abstract：:During attempts to select nonsecretory variants from 0.467.3, and Epstein-Barr virus-transformed human lymphoblastoid cell line that secretes small amounts of IgM lambda, we exposed the cells to UV light. Cells that survived the irradiation were subcultured and their supernatants were screened for immunoglobulin produ...

journal_title：Nature

authors： Rosén A,Klein G

更新日期：1983-11-10 00:00:00

abstract：:Throughout the lifespan of a plant, which in some cases can last more than one thousand years, the stem cell niches in the root and shoot apical meristems provide cells for the formation of complete root and shoot systems, respectively. Both niches are superficially different and it has remained unclear whether common...

journal_title：Nature

authors： Sarkar AK,Luijten M,Miyashima S,Lenhard M,Hashimoto T,Nakajima K,Scheres B,Heidstra R,Laux T

更新日期：2007-04-12 00:00:00

abstract：:Chromatin reorganization is governed by multiple post-translational modifications of chromosomal proteins and DNA. These histone modifications are reversible, dynamic events that can regulate DNA-driven cellular processes. However, the molecular mechanisms that coordinate histone modification patterns remain largely u...

journal_title：Nature

authors： Fujiki R,Hashiba W,Sekine H,Yokoyama A,Chikanishi T,Ito S,Imai Y,Kim J,He HH,Igarashi K,Kanno J,Ohtake F,Kitagawa H,Roeder RG,Brown M,Kato S

更新日期：2011-11-27 00:00:00

abstract：: ...

journal_title：Nature

authors： Liao SE

更新日期：2018-11-01 00:00:00

abstract：:Kalka is one of about 14 major layered mafic-ultramafic intrusions forming the Giles Complex in central Australia1. The stratigraphical section of the Kalka Intrusion passes from a basal pyroxenite zone (450 + m) through norite and olivine gabbro zones (3,500 m) to an uppermost anorthosite zone (800 + m)2. Further res...

journal_title：Nature

authors： Gray CM,Goode ADT

更新日期：1981-11-12 00:00:00

abstract：:THE cause of extinction of the woolly mammoth, Mammuthus primigenius (Blumenbach), is still debated. A major environmental change at the Pleistocene-Holocene boundary, hunting by early man, or both together are among the main explanations that have been suggested. But hardly anyone has doubted that mammoths had become...

journal_title：Nature

authors： Vartanyan SL,Garutt VE,Sher AV

更新日期：1993-03-25 00:00:00

abstract：:In mammalian somatic-cell cycles, progression through the G1-phase restriction point and initiation of DNA replication are controlled by the ability of the retinoblastoma tumour-suppressor protein (pRb) family to regulate the E2F/DP transcription factors. Continuing transcription of E2F target genes beyond the G1/S tr...

journal_title：Nature

authors： Lukas C,Sørensen CS,Kramer E,Santoni-Rugiu E,Lindeneg C,Peters JM,Bartek J,Lukas J

更新日期：1999-10-21 00:00:00

abstract：:Relative to the present day, meridional temperature gradients in the Early Eocene age ( approximately 56-53 Myr ago) were unusually low, with slightly warmer equatorial regions but with much warmer subtropical Arctic and mid-latitude climates. By the end of the Eocene epoch ( approximately 34 Myr ago), the first major...

journal_title：Nature

authors： Bijl PK,Schouten S,Sluijs A,Reichart GJ,Zachos JC,Brinkhuis H

更新日期：2009-10-08 00:00:00

abstract：:The Encyclopedia of DNA Elements (ENCODE) project has established a genomic resource for mammalian development, profiling a diverse panel of mouse tissues at 8 developmental stages from 10.5 days after conception until birth, including transcriptomes, methylomes and chromatin states. Here we systematically examined th...

journal_title：Nature

authors： Gorkin DU,Barozzi I,Zhao Y,Zhang Y,Huang H,Lee AY,Li B,Chiou J,Wildberg A,Ding B,Zhang B,Wang M,Strattan JS,Davidson JM,Qiu Y,Afzal V,Akiyama JA,Plajzer-Frick I,Novak CS,Kato M,Garvin TH,Pham QT,Harrington AN

更新日期：2020-07-01 00:00:00

abstract：:Rab GTPases regulate all stages of membrane trafficking, including vesicle budding, cargo sorting, transport, tethering and fusion. In the inactive (GDP-bound) conformation, accessory factors facilitate the targeting of Rab GTPases to intracellular compartments. After nucleotide exchange to the active (GTP-bound) conf...

journal_title：Nature

authors： Eathiraj S,Pan X,Ritacco C,Lambright DG

更新日期：2005-07-21 00:00:00

abstract：:The molecular mechanisms of exon definition and back-splicing are fundamental unanswered questions in pre-mRNA splicing. Here we report cryo-electron microscopy structures of the yeast spliceosomal E complex assembled on introns, providing a view of the earliest event in the splicing cycle that commits pre-mRNAs to sp...

journal_title：Nature

authors： Li X,Liu S,Zhang L,Issaian A,Hill RC,Espinosa S,Shi S,Cui Y,Kappel K,Das R,Hansen KC,Zhou ZH,Zhao R

更新日期：2019-09-01 00:00:00

abstract：:Sexual differences in the extent and type of parental care lie at the heart of sexual selection theory, and evolution resulting from parental conflict has produced some striking behavioural and morphological adaptations. In a study of male pregnancy in Gulf pipefish, Paczolt and Jones showed that more eggs were transf...

journal_title：Nature

authors： Gwynne DT,Judge KA,Kelly CD

更新日期：2010-08-26 00:00:00

abstract：:Thyroid hormones and retinoic acid function through nuclear receptors that belong to the steroid/thyroid-hormone receptor superfamily. Thyroid hormone receptors (TRs) and retinoic acid receptors (RARs) require auxiliary nuclear proteins for efficient DNA binding. Here we report that retinoid X receptors RXR alpha is o...

journal_title：Nature

authors： Zhang XK,Hoffmann B,Tran PB,Graupner G,Pfahl M

更新日期：1992-01-30 00:00:00

abstract：:Many corals bleach as a result of increased seawater temperature, which causes them to lose their vital symbiotic algae (Symbiodinium spp.) - unless these symbioses are able to adapt to global warming, bleaching threatens coral reefs worldwide. Here I show that some corals have adapted to higher temperatures, at least...

journal_title：Nature

authors： Rowan R

更新日期：2004-08-12 00:00:00

abstract：:B-RAF is the most frequently mutated protein kinase in human cancers. The finding that oncogenic mutations in BRAF are common in melanoma, followed by the demonstration that these tumours are dependent on the RAF/MEK/ERK pathway, offered hope that inhibition of B-RAF kinase activity could benefit melanoma patients. He...

journal_title：Nature

authors： Bollag G,Hirth P,Tsai J,Zhang J,Ibrahim PN,Cho H,Spevak W,Zhang C,Zhang Y,Habets G,Burton EA,Wong B,Tsang G,West BL,Powell B,Shellooe R,Marimuthu A,Nguyen H,Zhang KY,Artis DR,Schlessinger J,Su F,Higgins B,Iy

更新日期：2010-09-30 00:00:00

abstract：:The presence of homoeo box sequences in the genomes of vertebrates has suggested that these metazoans possess the equivalent of the homoeotic genes that have a key role in regulating the development of the fruitfly Drosophila melanogaster. We report here that a novel murine homoeo box-containing gene is expressed in e...

journal_title：Nature

authors： Colberg-Poley AM,Voss SD,Chowdhury K,Gruss P

更新日期：1985-04-25 00:00:00

abstract：:The mobilization of aluminium from acidic forest soils is arguably the most ecologically important consequence of acid deposition in the environment because of its adverse effects on soils, forest vegetation and surface water. Here we show that there has been a significant decline in the concentrations of aluminium sp...

journal_title：Nature

authors： Palmer SM,Driscoll CT

更新日期：2002-05-16 00:00:00