Abstract:
:The usefulness of antiandrogenic therapy with cyproterone acetate for androgenisation signs and symptoms in women, when tumours are definitely not the cause, has now been confirmed world-wide in about 100,000,000 therapy cycles using the hormonal contraceptive Diane and its follow-up preparation Diane-35, which contains a lower level of oestrogen. Nowadays, low-dose hormonal contraceptives are preferred in order to minimise the so-called "internal" risk by reducing the level of the oestrogen component and, by careful selection of the progestin, minimising the residual androgenic effect. In an open study on 150 women with moderately severe symptoms of androgenisation, we assessed, for treatment periods of up to 36 cycles, the effect of the only oestrogen-reduced hormonal contraceptive with anti-androgenic activity (Diane-35), and also monitored biochemical parameters, which are indicative of high risk metabolic activity and permit an accurate characterisation of the hormonal contraceptive, especially with long-term use. Although the parameters of liver and fat metabolism occasionally yielded values close to the limit of the normal range, it was particularly favourable to note, that the lipoprotein fraction HDL exhibited a slightly rising tendency, whereas, at the same time, the LDL fraction dropped. Special attention has been paid to ultrasonographic monitoring of the liver, since the influence on the function of this organ has been frequently discussed in conjunction with prolonged use of 17-alpha-alkylated steroidal compounds, and because a possible connection between sex steroids and the development of liver tumours has been a point of discussions.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Geburtshilfe Frauenheilkdjournal_title
Geburtshilfe und Frauenheilkundeauthors
Kaiser E,Gruner Sdoi
10.1055/s-2008-1026315subject
Has Abstractpub_date
1991-04-01 00:00:00pages
298-303issue
4eissn
0016-5751issn
1438-8804journal_volume
51pub_type
杂志文章abstract::Report on a 30-year old primigravida with a family history of bleeding and a personal history of nasopharyngeal bleeding since age four. Severe menorrhagia since her menarche. First seen at 20 weeks gestation with naso-pharyngeal bleeding and a twin pregnancy. The patient was found to have Glanzmann's disease (congeni...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:
更新日期:1978-04-01 00:00:00
abstract::The confusion of terms between the radiological literature and the gynaecological and anatomical literature regarding the definitions of the infantile and the hypoplastic uterus are described. The history of this confusion is traced. The two types of uterus were clearly defined by K. Menge and K.v. Oettingen in 1930. ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:
更新日期:1975-11-01 00:00:00
abstract::Today, echography can be considered as routine diagnosis in every pregnancy. Besides the detection of growth retardation very often in early stages of the fetal life malformations can be diagnosed incompatible with postnatal life. Reviewing the cases of the II. Women's Department of Obstetrics and Gynaecology in Vienn...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1037231
更新日期:1980-10-01 00:00:00
abstract::Today, hysterectomy internationally is nearly as frequent as appendectomy. In approx. 1% of all hysterectomies (vaginal or abdominal) where one or both ovaries are left, the residual ovary syndrome is found after an average period of slightly over five years. Predominant symptoms are diffused abdominal pain and palpab...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1037016
更新日期:1980-01-01 00:00:00
abstract::We report on the pregnancy and delivery of a 33-year old nullipara suffering from acute intermittent porphyria. Despite high risk of mortality and exacerbation of the disease, no complications occurred, since basic therapeutic principles were followed. ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036080
更新日期:1989-08-01 00:00:00
abstract::Introduction: Defects of the levator ani muscle complex could represent a pathophysiological link between vaginal birth trauma and urogynecological symptoms many years later. The aim of our study was to determine the prevalence of levator ani muscle defects using 3D or 4D ultrasound and palpation in urogynecological p...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0034-1396180
更新日期:2015-01-01 00:00:00
abstract::A retrospective analysis of 225 very low birth weight infants (less than 1500 g) was made, to assess the influence of the mode of delivery on the survival rate. In 186 preterm deliveries which could not be prevented by therapeutic measures, we included additionally certain gestational and perinatological parameters. G...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-1026154
更新日期:1991-05-01 00:00:00
abstract::This case report its on a haemorrhagic shock developing after amniocentesis during early pregnancy. Initially caused by a lesion of a small subserous artery in the upper uterine fundal wall, the patient consequently developed a protracted haemorrhagic shock that required emergency treatment and surgery. Thirteen days ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-1022812
更新日期:1995-07-01 00:00:00
abstract::34 patients received an intravenous bolus injection of 2 g ceftizoxime over 5 min at various times before abdominal or vaginal hysterectomy. Ceftizoxime concentrations in myometrium were substantially higher than in salpinges and endometrium. Tissue concentrations of 4 micrograms/g could be maintained for at least 3 h...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036734
更新日期:1983-11-01 00:00:00
abstract::A report is given of results and complications following postoperative irradiation in endometrial carcinoma via monitored high-dose afterloading therapy (iridium 192). Intravaginal irradiation was performed in all operated cases. In advanced cases or in cases with poor prognosis (deep infiltration of the myometrium, t...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035941
更新日期:1986-10-01 00:00:00
abstract::Purpose: In the years 1993-1996 a number of presumably false-positive breast cancer diagnoses were made by a pathologist in Essen. A follow-up, undertaken 15 years later, investigated how many women had tumour recurrence and/or metastasis or had died from breast cancer. Material and Methods: A total of 151 (68 %) out ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-0031-1298541
更新日期:2012-06-01 00:00:00
abstract::A laparotomy has been performed in a 49 years old woman. Preoperatively a large ovarian cystoma has been diagnosed. Factitiously a retroperitoneal lipoma was extirpated with a weight of 12,5 kg. ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:
更新日期:1979-02-01 00:00:00
abstract::More than ten years ago, the German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC) set up a panel of experts (VUS Task Force) which was tasked with reviewing the classifications of genetic variants reported by individual centres of the GC-HBOC to the central database in Leipzig and reclassifying them, w...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1110-0909
更新日期:2020-04-01 00:00:00
abstract::Textbooks and literature reports frequently view the primipara of advanced age as a group being at increased risk of prolonged labor, dystocia, injuries to the birth canal and fetal distress. Particularly, a rigid cervix and reduced elasticity of the soft tissues of the birth canal are claimed responsible for these ri...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1026496
更新日期:1988-04-01 00:00:00
abstract::Homologous insemination, a successful treatment for subfertile couples which utilizes a new method of preparation of the ejaculate, is described. To date 264 intrauterine inseminations have been performed in 106 couples. Determination of the causes of infertility, timing of ovulation and new methods of sperm preparati...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036389
更新日期:1985-09-01 00:00:00
abstract::This study on the metabolism of amino-acids following gynaecological operations confirms, that abdominal and vaginal hysterectomies cause a so-called post-aggression metabolism. The majority of the aminograms showed changes in the metabolism of nitrogen. The aminograms were carried out by the Stein-Moore chromatograph...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1037065
更新日期:1983-02-01 00:00:00
abstract::Clinical reports on successful hormonal treatment of climacteric or menopausal sexual dysfunctions are in contradiction with the lack of oestrous phenomena in humans as well as with the results of double-blind studies finding no objective proof for the alleged hormonal influence. A review of recent studies on the topi...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2007-1023732
更新日期:1993-11-01 00:00:00
abstract::Subperiosteal haematoma of the orbit is a rare event. It is a complication of a blunt cranial trauma. We describe a subperiosteal haematoma of the orbit in newborn after forceps delivery. ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1035775
更新日期:1987-01-01 00:00:00
abstract::The use of computers improves data storage capacity and leads to a homogeneous documentation of data obtained. After extensive preparations documentation was started using in 1975 the 2nd Department of Obstetrics and Gynecology computer. The obstetrical-gynecological data base is used for organisational, epidemiologic...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036408
更新日期:1989-05-01 00:00:00
abstract::Objective The aim of this study was to determine the present oral health status of pregnant women depending on selected sociodemographic differences and deduce any resulting consequences for health prevention. Methods The participants' data of relevance to the study such as age, school leaving qualification, migration...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/a-1205-0601
更新日期:2020-08-01 00:00:00
abstract::Puerperal uteri were stimulated by oxytocin, the uterine motility was recorded by transcervical catheter techniques, maternal pulse and blood-pressure were recorded continuously or intermittently. Oral tocolytics as Gynipral (Hexoprenaline), Partusisten (Fenoterol), Spiropent (Clenbuterol) and Prepar (Ritodrine) were ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 临床试验,杂志文章
doi:10.1055/s-2008-1036646
更新日期:1982-02-01 00:00:00
abstract::65 microcarcinomas and 189 Ca. in situ-cases were diagnosed by cone biopsy in the Department of Gynaecology and Obstetrics of the University in Kiel in the periods 1973-1976 and 1977-1980. During the first period the haemostasis of the conization crater was obtained by the conventional techniques. In 38% (microcarcino...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036799
更新日期:1982-06-01 00:00:00
abstract::Between October 1978 and December 1980 165 diagnostic laparoscopies were carried out because of the suspected diagnosis of primary tubal infertility. In this preselected series 27.9% of the cases had normal findings. It was remarkable that the previous diagnosis was not confirmed in 21 cases which had a prior infertil...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1037166
更新日期:1982-11-01 00:00:00
abstract::249 blood-flow measurements were carried out with pulsed Doppler-ultrasound in the umbilical arteries and the descending aorta of 188 fetuses. The PI and the RI of the recorded flowpatterns were calculated. In a retrospective study we then calculated the validity of the prediction of a pathological fetal outcome, i.e....
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1026632
更新日期:1988-11-01 00:00:00
abstract::In the present study the combination of tamoxifen and bromocriptine was tried for the suppression of prolactin in prolactin secreting adenomas which were resistant to suppression with bromoergocriptine alone. 10 women under treatment with 2.5-10 mg of parlodel (bromocriptine) for pituitary tumours of various sizes wer...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1037161
更新日期:1982-11-01 00:00:00
abstract::A case of squamous cell carcinoma infiltrating the stroma of cystosarcoma phylloides malignum is reported. A short review of prognosis and therapy is given on comparable cases. It is not uncommon to find squamous cell metaplasias in the dilated ducts of cystosarcoma phylloides. The combination of squamous cell carcino...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2008-1036322
更新日期:1984-10-01 00:00:00
abstract::The administration of GnRH analogues is expected to improve treatment by avoiding hysterectomy, since problems connected with the surgical removal of leiomyomata are correlated with their size. In this study the GnRH analogue goserelin in its depot formulation (Zoladex, ICI, Plankstadt) was used for treating isolated ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-1026451
更新日期:1990-02-01 00:00:00
abstract::The specific disadvantage of the Vecchietti technique for construction of a vagina in cases of vaginal agenesis is the need for laparotomy. We describe an endoscopically assisted construction of a vagina by a variation of this method and report on the first five cases operated on without any complications and with goo...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:10.1055/s-2007-1023676
更新日期:1993-04-01 00:00:00
abstract::Three million out of 4.5 million foreigners in Germany are from countries, where sickle cell anaemia is found. Today, this disease occurs in Germany with sufficient frequency and this makes it imperative for every physician to be familiar with it. Most of the sickle cell patients today attain the reproductive age. Dur...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章,评审
doi:10.1055/s-2008-1026275
更新日期:1990-06-01 00:00:00
abstract::The management of singleton breech deliveries in a referral hospital of an exclusively rural area is described. Since many cases are referred during labour after an attempted domiciliary delivery a primary vaginal delivery with extended indications for Caesarean Section is the general plan of management. Between 1971 ...
journal_title:Geburtshilfe und Frauenheilkunde
pub_type: 杂志文章
doi:
更新日期:1977-08-01 00:00:00