Abstract:
:A new system has been developed for measuring the forces produced by a small number (less than 5-150) of myosin molecules interacting with a single actin filament in vitro. The technique can resolve forces of less than a piconewton and has a time resolution in the submillisecond range. It can thus detect fluctuations of force caused by individual molecular interactions. From analysis of these force fluctuations, the coupling between the enzymatic ATPase activity of actomyosin and the resulting mechanical impulses can be elucidated.
journal_name
Naturejournal_title
Natureauthors
Ishijima A,Doi T,Sakurada K,Yanagida Tdoi
10.1038/352301a0subject
Has Abstractpub_date
1991-07-25 00:00:00pages
301-6issue
6333eissn
0028-0836issn
1476-4687journal_volume
352pub_type
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