Links between core promoter and basic gene features influence gene expression.

abstract：BACKGROUND:The most critical step in the pearl formation during aquaculture is issued to the proliferation and differentiation of outer epithelial cells of mantle graft into pearl sac. This pearl sac secretes various matrix proteins to produce pearls by a complex physiological process which has not been well-understood...

journal_title：BMC genomics

authors： Mariom,Take S,Igarashi Y,Yoshitake K,Asakawa S,Maeyama K,Nagai K,Watabe S,Kinoshita S

更新日期：2019-03-25 00:00:00

abstract：BACKGROUND:Mitochondrial genomes comprise a small but critical component of the total DNA in eukaryotic organisms. They encode several key proteins for the cell's major energy producing apparatus, the mitochondrial respiratory chain. Additionally, their nucleotide and amino acid sequences are of great utility as marker...

journal_title：BMC genomics

authors： Lloyd RE,Foster PG,Guille M,Littlewood DT

更新日期：2012-09-19 00:00:00

abstract：BACKGROUND:Alternative synonymous codons are not used with equal frequencies. In addition, the contexts of codons - neighboring nucleotides and neighboring codons - can have certain patterns. The codon context can influence both translational accuracy and elongation rates. However, it is not known how strong or conserv...

journal_title：BMC genomics

authors： Tats A,Tenson T,Remm M

更新日期：2008-10-08 00:00:00

abstract：BACKGROUND:Actinobacillus pleuropneumoniae causes pleuropneumonia in pigs, a disease which is associated with high morbidity and mortality, as well as impaired animal welfare. To obtain in-depth understanding of this infection, the interplay between virulence factors of the pathogen and defense mechanisms of the porcin...

journal_title：BMC genomics

authors： Brogaard L,Klitgaard K,Heegaard PM,Hansen MS,Jensen TK,Skovgaard K

更新日期：2015-05-28 00:00:00

abstract：BACKGROUND:Soybean (Glycine max (L. Merr.)) resistance to any population of Heterodera glycines (I.), or Fusarium virguliforme (Akoi, O'Donnell, Homma & Lattanzi) required a functional allele at Rhg1/Rfs2. H. glycines, the soybean cyst nematode (SCN) was an ancient, endemic, pest of soybean whereas F. virguliforme caus...

journal_title：BMC genomics

authors： Srour A,Afzal AJ,Blahut-Beatty L,Hemmati N,Simmonds DH,Li W,Liu M,Town CD,Sharma H,Arelli P,Lightfoot DA

更新日期：2012-08-02 00:00:00

abstract：BACKGROUND:Alternative σ factors are important transcriptional regulators in bacteria. While σ(B) has been shown to control a large regulon and play important roles in stress response and virulence in the pathogen Listeria monocytogenes, the function of σ(H) has not yet been well defined in Listeria, even though σ(H) c...

journal_title：BMC genomics

authors： Liu Y,Orsi RH,Boor KJ,Wiedmann M,Guariglia-Oropeza V

更新日期：2016-02-16 00:00:00

abstract：BACKGROUND:As is true for many other antibiotic-resistant Gram-negative pathogens, members of the Burkholderia cepacia complex (BCC) are currently being assessed for their susceptibility to phage therapy as an antimicrobial treatment. The objective of this study was to perform genomic and limited functional characteriz...

journal_title：BMC genomics

authors： Lynch KH,Abdu AH,Schobert M,Dennis JJ

更新日期：2013-08-27 00:00:00

abstract：BACKGROUND:The androgen receptor plays a critical role throughout the progression of prostate cancer and is an important drug target for this disease. While chromatin immunoprecipitation coupled with massively parallel sequencing (ChIP-Seq) is becoming an essential tool for studying transcription and chromatin modifica...

journal_title：BMC genomics

authors： Zhu Z,Shi M,Hu W,Estrella H,Engebretsen J,Nichols T,Briere D,Hosea N,Los G,Rejto PA,Fanjul A

更新日期：2012-07-31 00:00:00

abstract：BACKGROUND:The variability in gene organization and architecture of green algal mitochondrial genomes is only recently being studied on a finer taxonomic scale. Sequenced mt genomes from the chlorophycean orders Volvocales and Sphaeropleales exhibit considerable variation in size, content, and structure, even among clo...

journal_title：BMC genomics

authors： Farwagi AA,Fučíková K,McManus HA

更新日期：2015-10-21 00:00:00

abstract：BACKGROUND:Oxidative stress caused by ground level ozone is a contributor to yield loss in a number of important crop plants. Soybean (Glycine max) is considered to be ozone sensitive, and current research into its response to oxidative stress is limited. To better understand the genetic response in soybean to oxidativ...

journal_title：BMC genomics

authors： Whaley A,Sheridan J,Safari S,Burton A,Burkey K,Schlueter J

更新日期：2015-06-04 00:00:00

abstract：BACKGROUND:In our previous study, Citrobacter werkmanii BF-6 was isolated from an industrial spoilage sample and demonstrated an excellent ability to form biofilms, which could be affected by various environmental factors. However, the genome sequence of this organism has not been reported so far. RESULTS:We report th...

journal_title：BMC genomics

authors： Zhou G,Peng H,Wang YS,Huang XM,Xie XB,Shi QS

更新日期：2017-10-10 00:00:00

abstract：BACKGROUND:Cadmium (Cd) is a serious heavy metal (HM) soil pollutant. To alleviate or even eliminate HM pollution in soil, environmental-friendly methods are applied. One is that special plants are cultivated to absorb the HM in the contaminated soil. As an excellent economical plant with ornamental value and sound ada...

journal_title：BMC genomics

authors： Wang MQ,Bai ZY,Xiao YF,Li Y,Liu QL,Zhang L,Pan YZ,Jiang BB,Zhang F

更新日期：2019-11-20 00:00:00

abstract：BACKGROUND:Exiguobacterium antarcticum strain B7 is a Gram-positive psychrotrophic bacterial species isolated in Antarctica. Although this bacteria has been poorly studied, its genome has already been sequenced. Therefore, it is an appropriate model for the study of thermal adaptation. In the present study, we analyzed...

journal_title：BMC genomics

authors： Dall'Agnol HP,Baraúna RA,de Sá PH,Ramos RT,Nóbrega F,Nunes CI,das Graças DA,Carneiro AR,Santos DM,Pimenta AM,Carepo MS,Azevedo V,Pellizari VH,Schneider MP,Silva A

更新日期：2014-11-18 00:00:00

abstract：BACKGROUND:The Gram-negative bacterium Chlamydia pneumoniae (Cpn) is the leading intracellular human pathogen responsible for respiratory infections such as pneumonia and bronchitis. Basic and applied research in pathogen biology, especially the elaboration of new mechanism-based anti-pathogen strategies, target discov...

journal_title：BMC genomics

authors： Maier CJ,Maier RH,Virok DP,Maass M,Hintner H,Bauer JW,Onder K

更新日期：2012-11-16 00:00:00

abstract：BACKGROUND:The golden birdwing butterfly (Troides aeacus formosanus) is a rarely observed species in Taiwan. Recently, a typical symptom of nuclear polyhedrosis was found in reared T. aeacus larvae. From the previous Kimura-2 parameter (K-2-P) analysis based on the nucleotide sequence of three genes in this isolate, po...

journal_title：BMC genomics

authors： Huang YF,Chen TH,Chang ZT,Wang TC,Lee SJ,Kim JC,Kim JS,Chiu KP,Nai YS

更新日期：2019-05-27 00:00:00

abstract：BACKGROUND:Gene expression profiling is a promising approach to better estimate patient prognosis; however, there are still unresolved problems, including little overlap among similarly developed gene sets and poor performance of a developed gene set in other datasets. RESULTS:We applied a gene sets approach to develo...

journal_title：BMC genomics

authors： Kim SY,Kim YS

更新日期：2008-04-16 00:00:00

abstract：BACKGROUND:Bacteria in the genus Ruminococcus are ubiquitous members of the mammalian gastrointestinal tract. In particular, they are important in ruminants where they digest a wide range of plant cell wall polysaccharides. For example, Ruminococcus albus 7 is a primary cellulose degrader that produces acetate usable b...

journal_title：BMC genomics

authors： Christopherson MR,Dawson JA,Stevenson DM,Cunningham AC,Bramhacharya S,Weimer PJ,Kendziorski C,Suen G

更新日期：2014-12-04 00:00:00

abstract：BACKGROUND:Photorhabdus luminescens is an enteric bacterium, which lives in mutualistic association with soil nematodes and is highly pathogenic for a broad spectrum of insects. A complete genome sequence for the type strain P. luminescens subsp. laumondii TT01, which was originally isolated in Trinidad and Tobago, has...

journal_title：BMC genomics

authors： Zamora-Lagos MA,Eckstein S,Langer A,Gazanis A,Pfeiffer F,Habermann B,Heermann R

更新日期：2018-11-29 00:00:00

abstract：BACKGROUND:Genome-wide association studies (GWAS) have identified many common polymorphisms associated with complex traits. However, these associated common variants explain only a small fraction of the phenotypic variances, leaving a substantial portion of genetic heritability unexplained. As a result, searches for "m...

journal_title：BMC genomics

authors： Chen Q,Sun F

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:In clinical and basic research custom panels for transcript profiling are gaining importance because only project specific informative genes are interrogated. This approach reduces costs and complexity of data analysis and allows multiplexing of samples. Polymerase-chain-reaction (PCR) based TaqMan assays ha...

journal_title：BMC genomics

authors： Zhang JD,Schindler T,Küng E,Ebeling M,Certa U

更新日期：2014-07-05 00:00:00

abstract：BACKGROUND:The recently developed RNA interference (RNAi) technology has created an unprecedented opportunity which allows the function of individual genes in whole organisms or cell lines to be interrogated at genome-wide scale. However, multiple issues, such as off-target effects or low efficacies in knocking down ce...

journal_title：BMC genomics

authors： Wang L,Tu Z,Sun F

更新日期：2009-05-12 00:00:00

abstract：BACKGROUND:Regulation of bacterial gene expression by small RNAs (sRNAs) have proved to be important for many biological processes. Francisella tularensis is a highly pathogenic Gram-negative bacterium that causes the disease tularaemia in humans and animals. Relatively little is known about the regulatory networks exi...

journal_title：BMC genomics

authors： Postic G,Frapy E,Dupuis M,Dubail I,Livny J,Charbit A,Meibom KL

更新日期：2010-11-10 00:00:00

abstract：BACKGROUND:Protein phosphorylation by kinases plays crucial roles in various biological processes including signal transduction and tumorigenesis, thus a better understanding of protein phosphorylation events in cells is fundamental for studying protein functions and designing drugs to treat diseases caused by the malf...

journal_title：BMC genomics

authors： Ma H,Li G,Su Z

更新日期：2020-08-04 00:00:00

abstract：BACKGROUND:The ballan wrasse (Labrus bergylta) belongs to a large teleost family containing more than 600 species showing several unique evolutionary traits such as lack of stomach and hermaphroditism. Agastric fish are found throughout the teleost phylogeny, in quite diverse and unrelated lineages, indicating stomach ...

journal_title：BMC genomics

authors： Lie KK,Tørresen OK,Solbakken MH,Rønnestad I,Tooming-Klunderud A,Nederbragt AJ,Jentoft S,Sæle Ø

更新日期：2018-03-06 00:00:00

abstract：BACKGROUND:It is unclear whether improving feed efficiency by selection for low residual feed intake (RFI) compromises pigs' immunocompetence. Here, we aimed at investigating whether pig lines divergently selected for RFI had different inflammatory responses to lipopolysaccharide (LPS) exposure, regarding to clinical p...

journal_title：BMC genomics

authors： Liu H,Feye KM,Nguyen YT,Rakhshandeh A,Loving CL,Dekkers JCM,Gabler NK,Tuggle CK

更新日期：2019-10-11 00:00:00

abstract：BACKGROUND:The complete sequences of chloroplast genomes provide wealthy information regarding the evolutionary history of species. With the advance of next-generation sequencing technology, the number of completely sequenced chloroplast genomes is expected to increase exponentially, powerful computational tools annota...

journal_title：BMC genomics

authors： Liu C,Shi L,Zhu Y,Chen H,Zhang J,Lin X,Guan X

更新日期：2012-12-20 00:00:00

abstract：BACKGROUND:Ser/Thr/Tyr kinases (STYKs) commonly found in eukaryotes have been recently reported in many bacterial species. Recent studies elucidating their cellular functions have established their roles in bacterial growth and development. However functions of a large number of bacterial STYKs still remain elusive. Th...

journal_title：BMC genomics

authors： Krupa A,Srinivasan N

更新日期：2005-09-19 00:00:00

abstract：BACKGROUND:Guayule (Parthenium argentatum A. Gray) is a rubber-producing desert shrub native to Mexico and the United States. Guayule represents an alternative to Hevea brasiliensis as a source for commercial natural rubber. The efficient application of modern molecular/genetic tools to guayule improvement requires cha...

journal_title：BMC genomics

authors： Valdes Franco JA,Wang Y,Huo N,Ponciano G,Colvin HA,McMahan CM,Gu YQ,Belknap WR

更新日期：2018-04-19 00:00:00

abstract：BACKGROUND:Mitochondrial genomes of flowering plants (angiosperms) are highly dynamic in genome structure. The mitogenome of the earliest angiosperm Amborella is remarkable in carrying rampant foreign DNAs, in contrast to Liriodendron, the other only known early angiosperm mitogenome that is described as 'fossilized'. ...

journal_title：BMC genomics

authors： Dong S,Zhao C,Chen F,Liu Y,Zhang S,Wu H,Zhang L,Liu Y

更新日期：2018-08-14 00:00:00

abstract：BACKGROUND:The compromised performance of laying hens in the late phase of production relative to the peak production was thought to be associated with the impairment of intestinal functionality, which plays essential roles in contributing to their overall health and production performance. In the present study, RNA se...

journal_title：BMC genomics

authors： Wang WW,Wang J,Zhang HJ,Wu SG,Qi GH

更新日期：2019-12-12 00:00:00