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Effect of chitin/silk fibroin nanofibrous bicomponent structures on interaction with human epidermal keratinocytes.

Abstract：

:To fabricate a biomimetic nanostructured bicomponent scaffolds, two types of chitin/silk fibroin (SF) nanofibrous scaffolds (blend scaffolds and hybrid scaffolds) were prepared by electrospinning or simultaneous electrospinning of chitin/SF solutions. The chitin/SF bicomponent scaffolds were after-treated with water vapor, and their nanofibrous structures were almost maintained. From the cytocompatibility and cell behavior on the chitin/SF blend or hybrid nanofibrous scaffolds, the hybrid matrix with 25% chitin and 75% SF as well as the chitin/SF blend nanofibers could be a potential candidate for tissue engineering scaffolds.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Yoo CR,Yeo IS,Park KE,Park JH,Lee SJ,Park WH,Min BM

doi

10.1016/j.ijbiomac.2007.12.004

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

324-34

issue

4

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(07)00301-7

journal_volume

42

pub_type

杂志文章

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