Synthesis of dimeric phenol derivatives and determination of in vitro antioxidant and radical scavenging activities.

Abstract:

:In this study, di(2,6-dimethylphenol) (Di-DMP), di(2,6-diisopropylphenol) (Di-DIP, dipropofol) and di(2,6-di-t-butylphenol) (Di-DTP) were synthesized by the reaction of monomeric phenol derivatives with catalytic CuCl(OH). TMEDA and Na2S2O4. Their antioxidant capacity and radical scavenging activity were examined using different in vitro methodologies such as 1,1-diphenyl-2-picryl-hydrazyl (DPPH*) free radical scavenging, 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activity, total antioxidant activity by ferric thiocyanate, total reducing power by potassium ferricyanide reduction method, superoxide anion radical scavenging, hydrogen peroxide scavenging and ferrous ions chelating activities.

authors

Güllçin I,Daştan A

doi

10.1080/14756360601164903

subject

Has Abstract

pub_date

2007-12-01 00:00:00

pages

685-95

issue

6

eissn

1475-6366

issn

1475-6374

journal_volume

22

pub_type

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