Abstract：
:Adenohypophysial primordia of rat embryos at 13 to 15 days gestation were cultured in Parker 199 synthetic medium for 2 to 11 days. At the end of the culture period their fine structure and the presence of immunoreactive trophic hormones using the peroxidase-labeled antibody technique were investigated. The degree of differentiation in the glands depends largely on the age of the embryos furnishing the explants. Cultured pituitaries explanted on the 13th day of gestation contain only ACTH-positive cells and about 15% of the cells are granular. The granules are 50-100 nm in diameter in some cells, while in other cells they range from 50 to 200 nm. In cultivated adenohypophysial primordia of embryos on the 15th day of intrauterine life ACTH, prolactin, LH and TSH cells are evident, but only the same two kinds of granular cells can be observed with the electron microscope. The extent of cytodifferentiation in the glands explanted on the 14th day of gestation is intermediate between the two other groups. The data suggest that the fetal rat pituitary has the capacity of self-differentiation but to a lesser extent than that of the in situ hypophysis.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Nemeskéry A,Németh A,Sétáló G,Vigh S,Halász Bdoi
10.1007/BF00224303subject
Has Abstractpub_date
1976-07-26 00:00:00pages
263-73issue
2eissn
0302-766Xissn
1432-0878journal_volume
170pub_type
杂志文章abstract：:Purinoceptor subtypes were localised to various tissue types present within the nasal cavity of the rat, using immunohistochemical methods. P2X3 receptor immunoreactivity was localised in the primary olfactory neurones located both in the olfactory epithelium and vomeronasal organs (VNO) and also on subepithelial nerv...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0979-2
更新日期：2005-01-01 00:00:00
abstract：:Interstitial cells in the myenteric plexus and the deep muscular plexus of the small intestine of the c-kit mutant rats (Ws/Ws) and their normal siblings (+/+) were studied. c-Kit immunoreactivity was detected in two regions corresponding to the myenteric plexus and the deep muscular plexus in the jejunum of +/+ rats,...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051119
更新日期：1998-08-01 00:00:00
abstract：:The uptake of macromolecules and larger energy-rich particles into the cell is known as phagocytosis. Phagocytosed material is enzymatically degraded in membrane-bound vesicles of the endosome/lysosome system (intracellular digestion). Whereas most, if not all, cells of the animal body are equipped with the molecular ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-019-03096-6
更新日期：2019-09-01 00:00:00
abstract：:It is clear that the well-described phenomenon of epithelial-mesenchymal transition (EMT) plays a pivotal role in embryonic development, wound healing, tissue regeneration, organ fibrosis and cancer progression. EMTs have been classified into three subtypes based on the functional consequences and biomarker context in...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-011-1227-1
更新日期：2012-01-01 00:00:00
abstract：:A major difficulty in the investigation of interstitial cells of Cajal (ICC) is in identifying these cells within intact, living gastrointestinal tissues. To overcome this difficulty we developed a method to visualize ICC in the myenteric plexus region (ICC-MP) of the guinea pig ileum. Cells were identified with Nomar...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-001-0474-y
更新日期：2002-01-01 00:00:00
abstract：:The pineal organ of the eel, Anguilla anguilla was studied light-and electron-microscopically. The tissue consists predominantly of glia-like supporting cells and photoreceptor-like sensory cells, which establish synaptic contacts with pineal nerve cells. Histochemically, a positive acetylcholinesterase (AchE) reactio...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00238650
更新日期：1981-01-01 00:00:00
abstract：:Poreless sensilla (np-sensilla) on the antennae of 18 species from 9 insect orders, and on the maxillary palps of Periplaneta americana were investigated using chemo- and cryofixation. The number of np-sensilla is low. Common features of these sensilla are: (a) the presence of a peg, (b) the lack of pores that lead to...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00213769
更新日期：1983-01-01 00:00:00
abstract：:The true surface of rabbit spinal ganglion neurons has been made directly accessible to scanning electron-microscope observation after removal of both the connective tissue and satellite cells that normally cover it. The neuronal surface is characterized by a profusion of slender projections whose shapes have been det...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00297502
更新日期：1990-04-01 00:00:00
abstract：:Ossification of calvariae from day-21 rat fetuses was reinvestigated by electron microscopy using different fixation techniques (glutaraldehyde/OsO4, tannic acid, ruthenium red, K-pyroantimonate). An osteoid layer with scattered mineral deposits was found at the mineralization front. Directly beyond this layer, a shee...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00318693
更新日期：1992-01-01 00:00:00
abstract：:The azygos vein of the rat can be divided into three regions: The proximal cardiac region, where the wall is composed of two and sometimes three layers of cardiac muscle and a thin discontinuous layer of smooth muscle cells. Vascular casts of this region demonstrate layers of capillaries closely following the orientat...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221867
更新日期：1986-01-01 00:00:00
abstract：:Previous investigations have demonstrated that peripheral insulin has a significant influence on brain function and that the interaction of insulin with neuropeptides in neuroendocrine regions may be pivotal for the regulation of body metabolism and energy balance. Since the various levels of interactions are only inc...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050833
更新日期：1997-06-01 00:00:00
abstract：:In developing bioassays for estrogenic effects, vitellogenin (Vtg) induction and zona radiata protein (Zr-protein) induction in males and juveniles of oviparous vertebrates have been used as sensitive biomarkers for estrogenicity. Nonylphenol (NP) produces similar and parallel expression patterns of Vtg and Zr-protein...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0543-y
更新日期：2008-03-01 00:00:00
abstract：:Extracellular matrix (ECM) plays a dynamic role during tissue development and re-growth. Body part regeneration efficiency relies also on effective ECM remodelling and deposition. Among invertebrates, echinoderms are well known for their striking regenerative abilities since they can rapidly regenerate functioning com...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-020-03201-0
更新日期：2020-09-01 00:00:00
abstract：:More than twenty different enzyme activities of fractions containing dictyosome-like structures (DLS) as a dominant cell component were monitored. Plasma membrane vesicles were a major contaminant of the DLS fractions, which, presumably as a consequence, were enriched somewhat in plasma membrane markers. The lysosomal...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217555
更新日期：1985-01-01 00:00:00
abstract：:The spatial localisation of insulin-like growth-factor-binding protein-2 (IGFBP-2) and its mRNA was investigated during larval and post-larval developmental stages of the gilthead seabream ( Sparus aurata) by immunohistochemistry and in situ hybridisation with specific antisera and riboprobes. During larval developmen...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0952-0
更新日期：2005-01-01 00:00:00
abstract：:The transient receptor potential (TRP) superfamily comprises a group of non-selective cation channels that have been implicated in both receptor and store-operated channel functions. The family of the classical TRPs (TRPCs) consists of seven members (TRPC1-7). The presence of TRPC1 and TRPC5 mRNA in the brain has prev...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-0004-4
更新日期：2005-11-01 00:00:00
abstract：:Kainate receptors form a family of ionotropic glutamate receptors that appear to play a special role in the regulation of the activity of synaptic networks. This review first describes briefly the molecular and pharmacological properties of native and recombinant kainate receptors. It then attempts to outline the gene...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-006-0265-6
更新日期：2006-11-01 00:00:00
abstract：:In recent years, data have accumulated suggesting that the role of neurotrophins and Trk receptors may not be limited to the nervous system, and the presence of these substances has been detected in a variety of vertebrate and invertebrate non-nervous tissues. This study was designed to map the expression of immunorea...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410000181
更新日期：2000-04-01 00:00:00
abstract：:The responses of non-neuronal cells to the degeneration of neuroblasts were studied in the spinal ganglia of the chick embryo. Reactive changes of the non-neuronal cells were not apparent during the early stage of degeneration of the neuroblast, but during the later stages of degeneration evidence was found suggesting...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00210032
更新日期：1978-06-26 00:00:00
abstract：:Intra-arterial injections of synthetic double-stranded RNA (polyinosinic:polycytidylic acid, PIPC) at a dose of 500 microg/kg evoked pronounced fever in guinea-pigs. PIPC-induced fever could be antagonized by treatment with the non-selective cyclooxygenase (COX) inhibitor diclofenac and was, in part, attenuated by the...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0386-6
更新日期：2007-06-01 00:00:00
abstract：:To obtain more information concerning the origin of dendritic reticulum cells, the development of germinal centers in the spleens of rabbits was investigated by conventional light microscopy, enzyme histochemistry, and electron microscopy. Washed sheep erythrocytes were used as antigen. Splenic tissue was examined on ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00237632
更新日期：1980-01-01 00:00:00
abstract：:The gene encoding H1t, a testicular variant of histone H1, is expressed in mammals during spermatogenesis. Northern blot and in situ hybridization has detected H1t mRNA only at the stage of pachytene spermatocytes. We have extended this analysis to more sensitive approaches and demonstrate, by RNase protection and ele...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050986
更新日期：1998-01-01 00:00:00
abstract：:To investigate the uptake and transport patterns of variously sized particles in Peyer's patches (PPs) of calves, intestinal loops were created in four newborn and two 2-month-old calves, and the loops were inoculated with various particles, including carbon black, fluorescein isothiocyanate (FITC)-labeled latex, FITC...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-009-0793-y
更新日期：2009-07-01 00:00:00
abstract：:Parachlorophenylalanine (pCPA), an inhibitor of tryptophan hydroxylase which depletes brain serotonin in higher vertebrates, was injected into freshwater eels. After 4 or 6 injections (200 mg/kg/day) or 10 injections (100 and 140 mg/kg/day), the animals are paler, with a low melanophore index. In the pituitary gland, ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00223217
更新日期：1978-07-13 00:00:00
abstract：:The diabetes (db/db) mutation (leptin-receptor defect) induces a hyperglycemic-hyperinsulinemic endometabolic environment that promotes hypercytolipidemic ovarian involution in C57BL/KsJ mice, resulting in reproductive sterility and eventual organoatrophy. The effectiveness of low-dose (1.0 microg/sc/3.5 day intervals...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0967-6
更新日期：2004-11-01 00:00:00
abstract：:Changes in the organisation and composition of extracellular matrix in human endometrium during the menstrual cycle and early pregnancy have been assessed by immunofluorescence. Amongst interstitial components, type-III and type V-collagens and fibronectin are present in endometrial stroma throughout the menstrual cyc...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221758
更新日期：1988-07-01 00:00:00
abstract：:The distribution of radioactivity in the rat hypothalamus after intraventricular injection of tritiated luteinizing hormone-releasing hormone (LH-RH) was studied by autoradiography and compared with that expected from Fick's second law which defines the character of ordinary diffusion. The results suggest that LH-RH p...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215317
更新日期：1976-05-13 00:00:00
abstract：:Ultrastructural studies of pancreatic islets have suggested that crinophagy provides a possible mechanism for intracellular degradation of insulin in the insulin-producing B-cells. In the present study, a quantitative estimation of crinophagy in mouse pancreatic islets was attempted by morphometric analysis of lysosom...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00213820
更新日期：1988-04-01 00:00:00
abstract：:Histological characterization of spinal fusions in Atlantic salmon (Salmo salar) has demonstrated shape alterations of vertebral body endplates, a reduced intervertebral space, and replacement of intervertebral cells by ectopic bone. However, the significance of the notochord during the fusion process has not been add...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-010-1069-2
更新日期：2010-12-01 00:00:00
abstract：:The postnatal maturation of regions of the epididymis and intragonadal segment of the deferens duct was studied in the rat by light- and transmission electron microscopy. Maturation of the genital duct starts in the distal cauda epididymidis and ductus deferens after one week of life, and one week later, in the more c...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215508
更新日期：1987-08-01 00:00:00
