Prepubertal serum inhibin B in cryptorchid infants and in monorchid boys with compensatory testicular hypertrophy.


OBJECTIVE:To investigate the prepubertal serum inhibin B levels in monorchid boys with compensatory testicular hypertrophy (CTH) and in surgically treated cryptorchid boys with normal testicular volume. DESIGN:Prospective study. SETTING:Pediatric Division, University of Verona, Italy. PATIENT(S):Thirty-two prepubertal boys: 11 monorchids with CTH and 21 cryptorchids. For comparison we analyzed 15 healthy boys. MAIN OUTCOME MEASURE(S):All patients underwent a GnRH agonist test. Inhibin B measurement was performed at basal time. RESULT(S):There was a significant difference in mean testicular volume between monorchid and cryptorchid or healthy children, with boys with CTH evidencing larger testicle volume. There was no significant difference in inhibin B levels between boys with CTH and cryptorchid, but the levels were significantly lower in both groups than in the control group. Boys with CTH had significantly higher serum levels of basal FSH than children with cryptorchid. The FSH peak response to GnRH agonist stimulation was significantly higher in boys with CTH than in those with cryptorchid. CONCLUSION(S):Monorchid infants with CTH showed low inhibin B and high FSH levels. Our finding may confirm the hypothesis that CTH is unable to prevent testicular insufficiency in adulthood. We suggest an early hormonal evaluation of boys with CTH at puberty, together with early sperm analysis.


Fertil Steril


Fertility and sterility


Gaudino R,Cavarzere P,Camilot M,Teofoli F,Zampieri N,Tatò L




Has Abstract


2008-12-01 00:00:00














  • High expression of luteinizing hormone receptors messenger RNA by human cumulus granulosa cells is in correlation with decreased fertilization.

    abstract:OBJECTIVE:To elucidate the LH receptor (LHR) expression patterns in human granulosa cells (GCs) from antral to preovulatory stages, and to investigate a correlation to oocyte function. DESIGN:Luteinized preovulatory GCs were obtained from preovulatory follicles aspirated during IVF (≥ 17 mm). The GCs from small- (<10 ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Maman E,Yung Y,Kedem A,Yerushalmi GM,Konopnicki S,Cohen B,Dor J,Hourvitz A

    更新日期:2012-03-01 00:00:00

  • Granulocyte colony-stimulating factor with or without stem cell factor extends time to premature ovarian insufficiency in female mice treated with alkylating chemotherapy.

    abstract:OBJECTIVE:To examine gonadal protective properties of granulocyte colony-stimulating factor (G-CSF) alone or in combination with stem cell factor (SCF) in female mice treated with high-dose alkylating chemotherapy. DESIGN:Experimental laboratory animal study. SETTING:Tertiary care academic hospital and research insti...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Skaznik-Wikiel ME,McGuire MM,Sukhwani M,Donohue J,Chu T,Krivak TC,Rajkovic A,Orwig KE

    更新日期:2013-06-01 00:00:00

  • The clinical value of salpingoscopy in tubal infertility.

    abstract::A specially designed rigid salpingoscope has been developed to allow inspection of the tubal mucosa during laparoscopy. The presence and extent of intratubal adhesion formation can be evaluated more accurately by this technique than by either HSG or laparoscopy. In 22 patients with bilateral hydrosalpinges, an intraut...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: De Bruyne F,Puttemans P,Boeckx W,Brosens I

    更新日期:1989-02-01 00:00:00

  • Effects of testosterone and dihydrotestosterone on spermatogenesis, rete testis fluid, and peripheral androgen levels in hypophysectomized rats.

    abstract::To compare the effects of testosterone (T) and dihydrotestosterone (DHT) on the maintenance and the restoration of spermatogenesis, hypophysectomized (APX) rats were treated daily for 35 days with 0.5 mg of T propionate (TP) or DHT propionate (DHTP) beginning 5 or 33 days after hypophysectomy. In the maintenance exper...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Harris ME,Bartke A,Weisz J,Watson D

    更新日期:1977-10-01 00:00:00

  • The role of tubal reconstructive surgery in the era of assisted reproductive technologies.

    abstract::Tubal reconstructive surgery has fewer indications in the era of assisted reproductive technologies than in the past, but is still appropriate and effective treatment for properly selected individuals. ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审


    authors: Practice Committee of American Society for Reproductive Medicine.

    更新日期:2008-11-01 00:00:00

  • Controlled trial of high spermatic vein ligation for varicocele in infertile men.

    abstract:OBJECTIVE:To determine whether high ligation is an effective treatment for infertile men with clinical varicocele. DESIGN:A randomized, controlled trial of high spermatic vein ligation was carried out. The patients were treated and observed for 3 years. SETTING:Infertility treatment clinic and andrology laboratory in...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Madgar I,Weissenberg R,Lunenfeld B,Karasik A,Goldwasser B

    更新日期:1995-01-01 00:00:00

  • Endometrial antigens involved in the autoimmunity of endometriosis.

    abstract::Serum and peritoneal fluid from five fertile women without endometriosis and serum (n = 23) and peritoneal fluid (n = 12) from infertile women with endometriosis were tested for the presence of antibodies against endometrial tissue antigens by a Western blot analysis. Antigens with molecular weights (MW) of 19, 31, 38...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Mathur S,Chihal HJ,Homm RJ,Garza DE,Rust PF,Williamson HO

    更新日期:1988-12-01 00:00:00

  • Inhibitory effects of danazol on steroidogenesis in cultured human granulosa cells.

    abstract::The effect of danazol on steroidogenesis in cultured human granulosa cells was studied. Granulosa cells obtained from antral follicles in the mid to late follicular phase were cultured for 2 to 6 days. Danazol (0.1 to 5 micrograms/ml) and human chorionic gonadotropin (hCG, 10 IU/ml), alone or in combination, were adde...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Olsson JH,Hillensjö T,Nilsson L

    更新日期:1986-08-01 00:00:00

  • Sperm chromatin structure assay parameters are not related to fertilization rates, embryo quality, and pregnancy rates in in vitro fertilization and intracytoplasmic sperm injection, but might be related to spontaneous abortion rates.

    abstract:OBJECTIVE:To investigate the relationship between sperm chromatin structure assay (SCSA) parameters, DNA fragmentation index (DFI) and high DNA stainability (HDS), and outcomes of IVF and intracytoplasmic sperm injection (ICSI). DESIGN:Retrospective review and prospective study. SETTING:Academic human reproduction la...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审


    authors: Lin MH,Kuo-Kuang Lee R,Li SH,Lu CH,Sun FJ,Hwu YM

    更新日期:2008-08-01 00:00:00

  • Postoperative adhesion formation after ovarian wedge resection with and without ovarian reconstruction in the rabbit.

    abstract::A rabbit model was used to examine adhesion formation after ovarian wedge resection with and without reapproximation of the ovarian cortex. A wedge resection was completed on one ovary with a scalpel, and the ovarian cortex was reapproximated using microsurgical technique. In the contralateral ovary, a wedge resection...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Brumsted JR,Deaton J,Lavigne E,Riddick DH

    更新日期:1990-04-01 00:00:00

  • Blastocyst development in single medium with or without renewal on day 3: a prospective cohort study on sibling donor oocytes in a time-lapse incubator.

    abstract:OBJECTIVE:To evaluate the efficiency of using a continuous (one-step) protocol with a single medium for the culture of human embryos in a time-lapse incubator (TLI). DESIGN:Prospective cohort study on sibling donor oocytes. SETTING:University-affiliated in vitro fertilization (IVF) center. PATIENT(S):Embryos from 59...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,随机对照试验


    authors: Costa-Borges N,Bellés M,Meseguer M,Galliano D,Ballesteros A,Calderón G

    更新日期:2016-03-01 00:00:00

  • Von Willebrand factor expression in endometrial endothelial cells in women with menorrhagia.

    abstract::This prospective study assessed von Willebrand factor (VWF) expression in the endometrium using immunohistochemical staining in women with menorrhagia with or without von Willebrand disease (VWD) compared with a control group of women with normal menstrual loss. Endometrial VWF expression is significantly lower in wom...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Agarwal U,El Sheikh S,Kulkarni A,Baff D,Kadir RA

    更新日期:2010-11-01 00:00:00

  • Novel fumarate hydratase mutation in a family with atypical uterine leiomyomas and hereditary leiomyomatosis and renal cell cancer.

    abstract:OBJECTIVE:To describe a novel mutation in the fumarate hydratase (FH) gene in a family with atypical uterine leiomyomas. DESIGN:Case report and review of the literature. SETTING:Academic community hospital. PATIENT(S):Three sisters who presented as nulligravidas aged 27-30 years with large atypical uterine leiomyoma...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Wheeler KC,Warr DJ,Warsetsky SI,Barmat LI

    更新日期:2016-01-01 00:00:00

  • In vitro effects of phthalate esters in human myometrial and leiomyoma cells and increased urinary level of phthalate metabolite in women with uterine leiomyoma.

    abstract:OBJECTIVE:To investigate the possible role of phthalate, a ubiquitous chemical used in consumer products, in the pathogenesis of uterine leiomyoma. DESIGN:Experimental and prospective case-control study using human samples. SETTING:University hospital. PATIENT(S):Fifty-three women with histologic evidence of uterine...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Kim JH,Kim SH,Oh YS,Ihm HJ,Chae HD,Kim CH,Kang BM

    更新日期:2017-04-01 00:00:00

  • Evaluation of ribonucleic acid amplification protocols for human oocyte transcriptome analysis.

    abstract:OBJECTIVE:To develop a reliable, reproducible, and sensitive method for investigating gene-expression profiles from individual human oocytes. DESIGN:Five commercially available protocols were investigated for their efficiency to amplify messenger RNA (mRNA) from 54 single human oocytes. Protocols resulting in sufficie...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Mantikou E,Bruning O,Mastenbroek S,Repping S,Breit TM,de Jong M

    更新日期:2016-02-01 00:00:00

  • Weak linkage in androgen receptor: identification of mutation-prone points.

    abstract:OBJECTIVE:Mutation within androgen receptor (AR) can be seen. Presently, prediction of protein nanostructure and function is a great challenge in the proteomics and structural genomics era. To identify the points vulnerable to mutation is a new trend to expand the knowledge on disorders in genomic and proteomic level o...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Wiwanitkit V

    更新日期:2009-01-01 00:00:00

  • Acid Tyrode's solution can stimulate parthenogenetic activation of human and mouse oocytes.

    abstract::Fresh and aged (24 hours after ovulation) human oocytes and recently ovulated mouse oocytes may be activated by exposure to acidified Tyrode's solution. No activation of either type of human oocyte was observed after exposure to hyaluronidase or pronase, but significant numbers of fresh mouse oocytes were activated af...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Johnson MH,Pickering SJ,Braude PR,Vincent C,Cant A,Currie J

    更新日期:1990-02-01 00:00:00

  • Time series analysis of transmesothelial invasion by endometrial stromal and epithelial cells using three-dimensional confocal microscopy.

    abstract:OBJECTIVE:To evaluate endometrial adhesion and invasion of peritoneal mesothelium. DESIGN:Descriptive study using confocal laser-scanning microscopy. SETTING:University-based laboratory. PATIENT(S):Women undergoing surgery for benign conditions. INTERVENTION(S):Fluorescence-labeled peritoneal mesothelial cells (PMC...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Witz CA,Cho S,Centonze VE,Montoya-Rodriguez IA,Schenken RS

    更新日期:2003-03-01 00:00:00

  • Study of nucleation status in the second cell cycle of human embryo and its impact on implantation rate.

    abstract:OBJECTIVE:To study nucleation status in two- and four-cell embryos and its effect on reproductive outcomes. DESIGN:Retrospective cohort study. SETTING:University-affiliated private center. PATIENT(S):A total of 1,679 embryos from 940 oocyte donation cycles from May 2012 to May 2014. INTERVENTION(S):None. MAIN OUTC...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Aguilar J,Rubio I,Muñoz E,Pellicer A,Meseguer M

    更新日期:2016-08-01 00:00:00

  • Myo-inositol may improve oocyte quality in intracytoplasmic sperm injection cycles. A prospective, controlled, randomized trial.

    abstract:OBJECTIVE:To determine the effects of myo-inositol on oocyte quality in polycystic ovary syndrome (PCOS) patients undergoing intracytoplasmic sperm injection (ICSI) cycles. DESIGN:A prospective, controlled, randomized trial. SETTING:Assisted reproduction centers. PATIENT(S):Sixty infertile PCO patients undergoing ov...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,随机对照试验


    authors: Papaleo E,Unfer V,Baillargeon JP,Fusi F,Occhi F,De Santis L

    更新日期:2009-05-01 00:00:00

  • Growth factor effects on endometrial epithelial cell differentiation and protein synthesis in vitro.

    abstract:OBJECTIVE:To develop a baseline for projected studies of a rat endometriosis model. DESIGN:We investigated the effects of two macrophage-related growth factors, platelet-derived growth factor (PDGF) and transforming growth factor-beta (TGF-beta), on proliferation, in vitro differentiation, and protein secretion of ute...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Whitworth CM,Mulholland J,Dunn RC,Glasser SR

    更新日期:1994-01-01 00:00:00

  • HOXA10 mutations in congenital absence of uterus and vagina.

    abstract:OBJECTIVE:To analyze the HOXA10 genes in CAUV patients for mutations. Congenital absence of the uterus and vagina (CAUV) is the most extreme female reproductive tract developmental defect known. The HOXA10 gene is expressed in the developing and adult uterus. Female mice with loss-of-function Hoxa10 gene mutations have...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Lalwani S,Wu HH,Reindollar RH,Gray MR

    更新日期:2008-02-01 00:00:00

  • Requirement of heart and neural crest derivatives-expressed transcript 2 during decidualization of human endometrial stromal cells in vitro.

    abstract:OBJECTIVE:To investigate the role of heart and neural crest derivatives-expressed transcript 2 (HAND2) during decidualization of human endometrial stromal cells (ESCs). DESIGN:In vitro experiment. SETTING:Research laboratory. PATIENT(S):Twenty-six patients undergoing hysterectomy for benign reasons. INTERVENTION(S)...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Shindoh H,Okada H,Tsuzuki T,Nishigaki A,Kanzaki H

    更新日期:2014-06-01 00:00:00

  • Ectopic pregnancy rates with frozen compared with fresh blastocyst transfer.

    abstract:OBJECTIVE:To compare the rate of ectopic pregnancy (EP) with fresh versus frozen blastocyst transfer in our program during the same time period. DESIGN:Retrospective analysis. SETTING:University IVF program. PATIENT(S):Women who achieved a clinical pregnancy after IVF between 1998 and 2005. INTERVENTION(S):In our p...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Jun SH,Milki AA

    更新日期:2007-09-01 00:00:00

  • Single port laparoscopy combined with vaginal cervicovaginal reconstruction in a patient with congenital atresia of the cervix.

    abstract:OBJECTIVE:To introduce an innovation that combines single port laparoscopic and Wharton-Sheares-George cervicovaginal reconstruction using a small intestinal submucosa (SIS) graft in a patient with congenital cervical atresia, absence of vagina, and incomplete uterine septum (U2aC4V4). DESIGN:Video article introducing...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Zhang X,Qiu J,Ding Y,Sun L,Hua K

    更新日期:2020-03-01 00:00:00

  • Pipeline for contraceptive development.

    abstract::The high rates of unplanned pregnancy reflect an unmet need for effective contraceptive methods for women, especially for individuals with health risks such as obesity, diabetes, hypertension, and other conditions that may contraindicate use of an estrogen-containing product. Improvements in safety, user convenience, ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审


    authors: Blithe DL

    更新日期:2016-11-01 00:00:00

  • Study of spermatogenesis and thickening of lamina propria in the human seminiferous tubules.

    abstract::The negative correlation between the thickness of the lamina propria and Johnsen's score count in individual seminiferous tubules was observed and the tubules with thin lamina propria indicated almost complete spermatogenesis. It is suggested that the thin lamina propria may be one of the good indicators of complete s...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Sato Y,Nozawa S,Iwamoto T

    更新日期:2008-10-01 00:00:00

  • Characterization of two heterozygous mutations of the oocyte activation factor phospholipase C zeta (PLCζ) from an infertile man by use of minisequencing of individual sperm and expression in somatic cells.

    abstract:OBJECTIVE:To examine the underlying factors leading to infertility in a male patient from whom phospholipase C zeta H398P (PLCζ(H398P), histidine > proline) and PLCζ(H233L) (histidine > leucine) mutations were previously identified. DESIGN:Laboratory-based study. SETTING:University laboratory. PATIENT(S):An infertil...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Kashir J,Konstantinidis M,Jones C,Heindryckx B,De Sutter P,Parrington J,Wells D,Coward K

    更新日期:2012-08-01 00:00:00

  • A technique for standardization and quality control of subjective sperm motility assessments in semen analysis.

    abstract:OBJECTIVE:To establish a quality control method to monitor and eventually to standardize the subjective assessment of sperm motility in conventional semen analysis. DESIGN:Quality control study running over 2 years. SETTING:University infertility clinic and andrology laboratory. PATIENT(S):Randomly chosen patients a...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Yeung CH,Cooper TG,Nieschlag E

    更新日期:1997-06-01 00:00:00

  • Endometriosis and infertility: a committee opinion.

    abstract::Women with endometriosis typically present with pelvic pain, infertility, or an adnexal mass, and may require surgery. Treatment of endometriosis in the setting of infertility raises a number of complex clinical questions that do not have simple answers. This document replaces the 2006 ASRM Practice Committee document...

    journal_title:Fertility and sterility

    pub_type: 杂志文章


    authors: Practice Committee of the American Society for Reproductive Medicine.

    更新日期:2012-09-01 00:00:00