当前位置： SCI文献检索 > PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA期刊下所有文献 > Developmental processes underlying the evolution of a derived foot morphology in salamanders.

Developmental processes underlying the evolution of a derived foot morphology in salamanders.

Abstract：

:Interdigital webbing has evolved repeatedly in tropical salamanders (bolitoglossines). This derived foot morphology is only one of many homoplastic traits in this diverse amphibian clade. Indeed, few if any morphological traits sort lineages within this clade. We investigate the processes underlying the homoplastic evolution of morphological characters in these salamanders by analyzing selective and developmental processes that generate interdigital webbing. We show that a pedomorphic developmental change generates the new foot morphology and that pedomorphosis affects a number of morphological traits, thus creating a developmental correlation among them. This correlation among traits is maintained across most species, thus facilitating the repeated evolution of traits. Although we find evidence that the changes in foot morphology are adaptive in one species, the evolution of webbing in all other species does not carry an adaptive signature. The new foot morphology therefore evolves repeatedly, even in the apparent absence of a direct selective advantage.

journal_name

Proc Natl Acad Sci U S A

journal_title

Proceedings of the National Academy of Sciences of the United States of America

authors

Jaekel M,Wake DB

doi

10.1073/pnas.0710216105

subject

Has Abstract

pub_date

2007-12-18 00:00:00

pages

20437-42

issue

51

eissn

0027-8424

issn

1091-6490

pii

0710216105

journal_volume

104

pub_type

杂志文章

相关文献

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA文献大全
  • Geometric cues for directing the differentiation of mesenchymal stem cells.

    abstract：:Significant efforts have been directed to understanding the factors that influence the lineage commitment of stem cells. This paper demonstrates that cell shape, independent of soluble factors, has a strong influence on the differentiation of human mesenchymal stem cells (MSCs) from bone marrow. When exposed to compet...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0903269107

    authors： Kilian KA,Bugarija B,Lahn BT,Mrksich M

    更新日期：2010-03-16 00:00:00

  • Compact steep-spectrum sources and the unified scheme.

    abstract：:The compact steep-spectrum sources (CSSs) are an interesting class of objects which are of subgalactic dimensions; they occur more frequently in high-frequency surveys because their spectra often turn over at lower frequencies. We have estimated the symmetry parameters of a well-defined sample of CSSs and compared the...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.92.25.11417

    authors： Saikia DJ

    更新日期：1995-12-05 00:00:00

  • Reorganization of an arid ecosystem in response to recent climate change.

    abstract：:Natural ecosystems contain many individuals and species interacting with each other and with their abiotic environment. Such systems can be expected to exhibit complex dynamics in which small perturbations can be amplified to cause large changes. Here, we document the reorganization of an arid ecosystem that has occur...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.94.18.9729

    authors： Brown JH,Valone TJ,Curtin CG

    更新日期：1997-09-02 00:00:00

  • The kinetic mechanism of myosin V.

    abstract：:Myosin V is an unconventional myosin proposed to be processive on actin filaments, analogous to kinesin on a microtubule [Mehta, A. D., et al. (1999) Nature (London) 400, 590-593]. To ascertain the unique properties of myosin V that permit processivity, we undertook a detailed kinetic analysis of the myosin V motor. W...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.96.24.13726

    authors： De La Cruz EM,Wells AL,Rosenfeld SS,Ostap EM,Sweeney HL

    更新日期：1999-11-23 00:00:00

  • Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase.

    abstract：:Hepatitis C virus (HCV) infection is associated with dysregulation of both lipid and glucose metabolism. As well as contributing to viral replication, these perturbations influence the pathogenesis associated with the virus, including steatosis, insulin resistance, and type 2 diabetes. AMP-activated protein kinase (AM...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0912426107

    authors： Mankouri J,Tedbury PR,Gretton S,Hughes ME,Griffin SD,Dallas ML,Green KA,Hardie DG,Peers C,Harris M

    更新日期：2010-06-22 00:00:00

  • Changes in neuromuscular junction endplate current time constants produced by sulfhydryl reagents.

    abstract：:The acetylcholine receptor is a protein that contains certain critical disulfide bonds. Experiments were designed to determine the role such bonds might play in the physiological activity of the receptor. Modification of the receptor with sodium bisulfite and diamide produced an increase in the time constants of the m...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.78.12.7806

    authors： Steinacker A,Zuazaga DC

    更新日期：1981-12-01 00:00:00

  • DNA methyltransferase 3B regulates duration of neural crest production via repression of Sox10.

    abstract：:Neural crest stem cells arise within the central nervous system but then undergo an epithelial-to-mesenchymal transition to migrate away and contribute to the peripheral nervous system and craniofacial skeleton. Here we show that DNA methyltransferase 3B (DNMT3B) is responsible for the loss of competence of dorsal neu...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1318408111

    authors： Hu N,Strobl-Mazzulla PH,Simoes-Costa M,Sánchez-Vásquez E,Bronner ME

    更新日期：2014-12-16 00:00:00

  • Effective amplification of long targets from cloned inserts and human genomic DNA.

    abstract：:We have used the polymerase chain reaction (PCR) to amplify up to 22 kb of the beta-globin gene cluster from human genomic DNA and up to 42 kb from phaga lambda DNA. We have also amplified 91 human genomic inserts of 9-23 kb directly from recombinant lambda plaques. To do this, we increased pH, added glycerol and dime...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.91.12.5695

    authors： Cheng S,Fockler C,Barnes WM,Higuchi R

    更新日期：1994-06-07 00:00:00

  • Competition between native topology and nonnative interactions in simple and complex folding kinetics of natural and designed proteins.

    abstract：:We compared folding properties of designed protein Top7 and natural protein S6 by using coarse-grained chain models with a mainly native-centric construct that accounted also for nonnative hydrophobic interactions and desolvation barriers. Top7 and S6 have similar secondary structure elements and are approximately equ...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0911844107

    authors： Zhang Z,Chan HS

    更新日期：2010-02-16 00:00:00

  • Estimation of continental Os/Os values by using Os/Os and Nd/Nd ratios in marine manganese nodules.

    abstract：:The relationship between (187)Os/(186)Os and (143)Nd/(144)Nd in different manganese nodule fields is used to determine the (187)Os/(186)Os ratio of the continental terrains bounding the major ocean basins. The Atlantic Ocean drainages yield (187)Os/(186)Os of about 11; the Pacific Ocean, between 25 and 36; and the wes...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.81.24.8032

    authors： Turekian KK,Luck JM

    更新日期：1984-12-01 00:00:00

  • Prevalence of neural collapse during the terminal phase of deep learning training.

    abstract：:Modern practice for training classification deepnets involves a terminal phase of training (TPT), which begins at the epoch where training error first vanishes. During TPT, the training error stays effectively zero, while training loss is pushed toward zero. Direct measurements of TPT, for three prototypical deepnet a...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.2015509117

    authors： Papyan V,Han XY,Donoho DL

    更新日期：2020-10-06 00:00:00

  • Production of active bovine tracheal antimicrobial peptide in milk of transgenic mice.

    abstract：:Tracheal antimicrobial peptide (TAP) is a member of the beta-defensin family of antibiotic peptides found in the tracheal mucosa of the cow. TAP gene expression in the bovine airway is inducible by lipopolysaccharide and inflammatory mediators, suggesting that it functions to protect the upper airway from infection. L...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.93.24.14118

    authors： Yarus S,Rosen JM,Cole AM,Diamond G

    更新日期：1996-11-26 00:00:00

  • Ubiquitination of lysine-331 by Kaposi's sarcoma-associated herpesvirus protein K5 targets HFE for lysosomal degradation.

    abstract：:The nonclassical MHC class I-related (MHC-I) molecule HFE controls cellular iron homeostasis by a mechanism that has not been fully elucidated. We examined the regulation of HFE by K5, the E3 ubiquitin ligase encoded by Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8), that is known to down-regulate classical MHC-I...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1003421107

    authors： Rhodes DA,Boyle LH,Boname JM,Lehner PJ,Trowsdale J

    更新日期：2010-09-14 00:00:00

  • Modeling an autism risk factor in mice leads to permanent immune dysregulation.

    abstract：:Increasing evidence highlights a role for the immune system in the pathogenesis of autism spectrum disorder (ASD), as immune dysregulation is observed in the brain, periphery, and gastrointestinal tract of ASD individuals. Furthermore, maternal infection (maternal immune activation, MIA) is a risk factor for ASD. Mode...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1202556109

    authors： Hsiao EY,McBride SW,Chow J,Mazmanian SK,Patterson PH

    更新日期：2012-07-31 00:00:00

  • Crystallography captures catalytic steps in human methionine adenosyltransferase enzymes.

    abstract：:The principal methyl donor of the cell, S-adenosylmethionine (SAMe), is produced by the highly conserved family of methionine adenosyltranferases (MATs) via an ATP-driven process. These enzymes play an important role in the preservation of life, and their dysregulation has been tightly linked to liver and colon cancer...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1510959113

    authors： Murray B,Antonyuk SV,Marina A,Lu SC,Mato JM,Hasnain SS,Rojas AL

    更新日期：2016-02-23 00:00:00

  • Erbin is a negative modulator of cardiac hypertrophy.

    abstract：:ErbB2 interacting protein (Erbin) is a widely expressed protein and participates in inhibition of several intracellular signaling pathways. Its mRNA has been found to be present in relatively high levels in the heart. However, its physiological role in the heart has not been explored. In the present work, we elucidate...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1320350111

    authors： Rachmin I,Tshori S,Smith Y,Oppenheim A,Marchetto S,Kay G,Foo RS,Dagan N,Golomb E,Gilon D,Borg JP,Razin E

    更新日期：2014-04-22 00:00:00

  • 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide: a partial modulator of AMPA receptor desensitization devoid of neurotoxicity.

    abstract：:In cerebellar granule neurons of neonatal rats micromolar concentrations of 7-chloro-3-methyl-3,4-dihydro-2H-1,2, 4-benzothiadiazine S,S-dioxide (IDRA-21) and cyclothiazide, two negative modulators of the spontaneous agonist-dependent rapid desensitization of alpha-amino-3-hydroxy-5-methylisoxazolepropionic acid (AMPA...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.94.13.7053

    authors： Impagnatiello F,Oberto A,Longone P,Costa E,Guidotti A

    更新日期：1997-06-24 00:00:00

  • Involvement of Lyt-2 and L3T4 in activation of hapten-specific Lyt-2+ L3T4+ T-cell clones.

    abstract：:The murine T-cell surface molecules Lyt-2 and L3T4 play a role in the activation of antigen-specific T cells. The currently accepted model for the function of these molecules proposes that Lyt-2 and L3T4 increase the overall avidity of the interaction between the T-cell antigen receptor and antigen in association with...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.83.8.2594

    authors： Fazekas de St Groth B,Gallagher PF,Miller JF

    更新日期：1986-04-01 00:00:00

  • Diverse regulation of mammary epithelial growth and branching morphogenesis through noncanonical Wnt signaling.

    abstract：:The mammary gland consists of an adipose tissue that, in a process called branching morphogenesis, is invaded by a ductal epithelial network comprising basal and luminal epithelial cells. Stem and progenitor cells drive mammary growth, and their proliferation is regulated by multiple extracellular cues. One of the key...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1701464114

    authors： Kessenbrock K,Smith P,Steenbeek SC,Pervolarakis N,Kumar R,Minami Y,Goga A,Hinck L,Werb Z

    更新日期：2017-03-21 00:00:00

  • Stress-induced heat shock protein 70 expression in adrenal cortex: an adrenocorticotropic hormone-sensitive, age-dependent response.

    abstract：:The induction of heat shock proteins (HSP) by cellular stress and the activation of the hypothalamic-pituitary-adrenal axis by physiologic stress are biological responses that aid in the maintenance of cellular and organismal homeostasis, respectively. In this report, restraint stress, known to activate the hypothalam...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.88.21.9873

    authors： Blake MJ,Udelsman R,Feulner GJ,Norton DD,Holbrook NJ

    更新日期：1991-11-01 00:00:00

  • Left-handed Z-DNA in bands of acid-fixed polytene chromosomes.

    abstract：:Antibodies to DNA in the left-handed (Z) conformation bind to acid-fixed polytene chromosomes of both Chironomus thummi and Drosophila melanogaster, as shown by direct and indirect immunofluorescence. Comparison of the phase-contrast, immunofluorescence, and DNA staining patterns shows a predominant localization of th...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.80.14.4344

    authors： Arndt-Jovin DJ,Robert-Nicoud M,Zarling DA,Greider C,Weimer E,Jovin TM

    更新日期：1983-07-01 00:00:00

  • Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R.

    abstract：:Precise spatiotemporal control of mRNA translation machinery is essential to the development of highly complex systems like the neocortex. However, spatiotemporal regulation of translation machinery in the developing neocortex remains poorly understood. Here, we show that an RNA-binding protein, Hu antigen R (HuR), re...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1408305111

    authors： Kraushar ML,Thompson K,Wijeratne HR,Viljetic B,Sakers K,Marson JW,Kontoyiannis DL,Buyske S,Hart RP,Rasin MR

    更新日期：2014-09-09 00:00:00

  • Antibodies specific for amino acid 12 of the ras oncogene product inhibit GTP binding.

    abstract：:An antibody (anti-p21ser) was raised against a ras p21-related synthetic peptide and was able to recognize specifically the substitution of serine for glycine at amino acid 12 of p21. This substitution causes oncogenic activation of p21. Anti-p21ser was found to immunoprecipitate v-Ki-ras p21 and to strongly inhibit i...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.82.16.5280

    authors： Clark R,Wong G,Arnheim N,Nitecki D,McCormick F

    更新日期：1985-08-01 00:00:00

  • El Nino/Southern Oscillation response to global warming.

    abstract：:The El Niño/Southern Oscillation (ENSO) phenomenon, originating in the Tropical Pacific, is the strongest natural interannual climate signal and has widespread effects on the global climate system and the ecology of the Tropical Pacific. Any strong change in ENSO statistics will therefore have serious climatic and eco...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0710860105

    authors： Latif M,Keenlyside NS

    更新日期：2009-12-08 00:00:00

  • Direct and synergistic effects of interleukin 11 on murine hemopoiesis in culture.

    abstract：:We have examined the effects of a stromal cell-derived cytokine designated interleukin 11 (IL-11) on the proliferation of murine hemopoietic progenitors in methylcellulose culture. COS cell-conditioned medium containing IL-11 supported formation of granulocyte/macrophage colonies and a small number of multilineage col...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.88.3.765

    authors： Musashi M,Yang YC,Paul SR,Clark SC,Sudo T,Ogawa M

    更新日期：1991-02-01 00:00:00

  • CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation.

    abstract：:Oriented cell division is critical for cell fate specification, tissue organization, and tissue homeostasis, and relies on proper orientation of the mitotic spindle. The molecular mechanisms underlying the regulation of spindle orientation remain largely unknown. Herein, we identify a critical role for cylindromatosis...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1319341111

    authors： Yang Y,Liu M,Li D,Ran J,Gao J,Suo S,Sun SC,Zhou J

    更新日期：2014-02-11 00:00:00

  • Self-referential phase reset based on inferior olive oscillator dynamics.

    abstract：:The olivo-cerebellar network is a key neuronal circuit that provides high-level motor control in the vertebrate CNS. Functionally, its network dynamics is organized around the oscillatory membrane potential properties of inferior olive (IO) neurons and their electrotonic connectivity. Because IO action potentials are ...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0407900101

    authors： Kazantsev VB,Nekorkin VI,Makarenko VI,Llinás R

    更新日期：2004-12-28 00:00:00

  • Localization and sequence of a vaccinia virus gene required for multiplication in human cells.

    abstract：:A vaccinia virus host range mutant (hr mutant) deleted of 18 kilobase pairs at the left end of the genome has been employed to precisely map a viral gene required for multiplication in human cells. DNA fragments from the wild-type virus were inserted into the thymidine kinase gene of mutant virus by means of in vivo h...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.83.15.5573

    authors： Gillard S,Spehner D,Drillien R,Kirn A

    更新日期：1986-08-01 00:00:00

  • Production of a functional eukaryotic enzyme in Escherichia coli: cloning and expression of the yeast structural gene for imidazole-glycerolphosphate dehydratase (his3).

    abstract：:A cloned segment of yeast DNA containing the structural gene for imidazoleglycerolphosphate dehydratase (D-erythro-imidazoleglycerolphosphate hydro-lase, EC 4.2.1.19) is transcribed and translated in Escherichia coli with sufficient fidelity to produce functional enzyme. This segment of yeast DNA was isolated as a via...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.74.12.5255

    authors： Struhl K,Davis RW

    更新日期：1977-12-01 00:00:00

  • Meta-mass shift chemical profiling of metabolomes from coral reefs.

    abstract：:Untargeted metabolomics of environmental samples routinely detects thousands of small molecules, the vast majority of which cannot be identified. Meta-mass shift chemical (MeMSChem) profiling was developed to identify mass differences between related molecules using molecular networks. This approach illuminates metabo...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1710248114

    authors： Hartmann AC,Petras D,Quinn RA,Protsyuk I,Archer FI,Ransome E,Williams GJ,Bailey BA,Vermeij MJA,Alexandrov T,Dorrestein PC,Rohwer FL

    更新日期：2017-10-31 00:00:00