Abstract：
:Cells migrating from the neural crest are known to septate the outflow tract of the developing heart, and to contribute to the formation of the arterial valves, their supporting sinuses, the coronary arteries and cardiac neural ganglia. Neural crest cells have also been suggested to contribute to development of the venous pole of the heart, but the extent and fate of such cells remains unclear. In this study, in the mouse, it is shown that cells from the neural crest contribute to the parasympathetic and, to a lesser extent, the sympathetic innervation of the venous pole of the heart. Nerves within the venous pole of the heart are shown to be of mixed origin, with some being derived from the neural crest, while others have an alternative origin, presumably placodal. The neurons innervating the nodal tissue, which can exert chronotropic effects on cardiac conduction, are shown not to be derived from the neural crest. In particular, no evidence was found to support previous suggestions that cells from the neural crest make a direct contribution to the myocardial atrioventricular conduction axis, although a small subset of these cells do co-localize with the developing left bundle branch. We have therefore confirmed that cells from the neural crest migrate to the venous pole of the heart, and that their major role is in the development of the parasympathetic innervation. In addition, in some embryos, a population of cells derived from the neural crest persist in the leaflets of the atrioventricular valves, but their role in subsequent development remains unknown.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Hildreth V,Webb S,Bradshaw L,Brown NA,Anderson RH,Henderson DJdoi
10.1111/j.1469-7580.2007.00833.xsubject
Has Abstractpub_date
2008-01-01 00:00:00pages
1-11issue
1eissn
0021-8782issn
1469-7580pii
JOA833journal_volume
212pub_type
杂志文章abstract：:Muscles are considered to play an important role in the ongoing daily loading of bone, especially in the masticatory apparatus. Currently, there are no measurements describing this role over longer periods of time. We made simultaneous and wireless in vivo recordings of habitual strains of the rabbit mandible and mass...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2011.01375.x
更新日期：2011-06-01 00:00:00
abstract：:The histological structure of the oesophagus of the camel in different parts of its course was investigated with tissues from seven camels, and with haematoxylin and eosin and Masson's trichrome stain. Gross dissections confirmed the orientation of the muscle fibres in the tunica muscularis. The epithelium showed heav...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1982-08-01 00:00:00
abstract：:Interference with venous outflow from a limb to stimulate fracture repair and bone growth has a long history, and its beneficial effects have been confirmed by many experimental and clinical studies. With the development of fracture fixation systems, the therapeutic use of circulatory intervention became redundant. Re...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：:The study of human anatomy can be found throughout the rich history of Persia. For thousands of years, morphological descriptions derived from this part of the world have contributed to and have helped form our current anatomical knowledge base. In this article we review the major influential Persian periods and the i...
journal_title：Journal of anatomy
pub_type： 历史文章,杂志文章
doi：10.1111/j.1469-7580.2007.00711.x
更新日期：2007-04-01 00:00:00
abstract：:Quantitative measurements of relative nerve density were achieved using computer-assisted image analysis of immunohistochemically and histochemically defined nerves in the conduction system of the guinea pig heart. All regions of the conduction system possessed a similar density of nerve fibres and fascicles displayin...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：:In the male rat the volumes of the several zones of the adrenal cortex were measured using a point-counting technique at various ages. The resulting growth curves were fitted by the Gompertz method, and the specific growth rate calculated for each zone at 14 days of age. Also at 14 days the flash labelling index was m...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1977-02-01 00:00:00
abstract：:Genetic mutation leads to anatomical variation only indirectly because many proteins involved in generating anatomical structures in embryos operate cooperatively within molecular networks. These include gene-regulatory or control networks (CNs) for timing, signaling and patterning together with the process networks (...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12205
更新日期：2014-08-01 00:00:00
abstract：:The translocation of mitochondria towards the primitive inner segment of the cones in the tree shrew Tupaia belangeri was investigated by transmission electron microscopy. Throughout ontogeny the migrating mitochondria were codistributed with cytoplasmic microtubules which were preserved after the application of conve...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease with clinical, pathological and genetic overlap with frontotemporal dementia (FTD). No longer viewed as one disease with a single unified cause, ALS is now considered to be a clinicopathological syndrome resulting from a complex convergence of ...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1111/joa.12107
更新日期：2014-01-01 00:00:00
abstract：:Experimental evidence indicates that lymph nodes in humans undergo alterations during ageing. This is clinically important because of the crucial role of these organs in the immune system and their lymph reabsorption and drainage function. Although some age-related changes in lymph node histoarchitecture have been des...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2010.01213.x
更新日期：2010-05-01 00:00:00
abstract：:Genital tubercles of male and female rats were cultured beneath the renal capsule of castrated and intact adult male rats treated with androgens, oestrogen, or anti-androgen, and the development of the os penis in the transplants was studied. When the genital tubercles were cultured in normal male hosts, a membrane bo...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1986-12-01 00:00:00
abstract：:A morphometric analysis was made of nuclei and cytoplasmic structures in electron micrographs of chondrocytes in the non-calcified layer of articular cartilage of the femoral condyles in adult mouse and dog and of the human incus. Mitochondrial volume density (% cytoplasm) was lower in dog than in mouse cells or cells...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：:The primary aim of this study is to broadly evaluate the relationship between cursoriality (i.e. anatomical and physiological specialization for running) and limb bone morphology in lagomorphs. Relative to most previous studies of cursoriality, our focus on a size-restricted, taxonomically narrow group of mammals perm...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12220
更新日期：2014-10-01 00:00:00
abstract：:The vomeronasal system (VNS) has been extensively studied within specific animal families, such as Rodentia. However, the study of the VNS in other families, such as Canidae, has long been neglected. Among canids, the vomeronasal organ (VNO) has only been studied in detail in the dog, and no studies have examined the ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13254
更新日期：2020-11-01 00:00:00
abstract：:Collagen fibrils from different rat tendons have been investigated by freeze-fracture and transmission electron microscopy. In all cases, marked differences in both fibril morphology and subfibrillar organisation have been consistently found between the tendon core (composed of large and heterogeneous fibrils comprisi...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1990-10-01 00:00:00
abstract：:The neurotropic effect of the distal stump of transected sciatic nerve on regenerating axons emerging from the proximal stump was investigated in rats by the coculture of excised neonatal dorsal root ganglia and segments of degenerated and nondegenerated sciatic nerves. In all cultures, neurites from the ganglion exte...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
abstract：:The distribution of muscle fibres classified on the basis of their content of different myosin heavy chain (MHC) isoforms was analysed in vastus lateralis muscle biopsies of 15 young men (with an average age of 22 y) by correlating immunohistochemistry with specific anti-MHC monoclonal antibodies, myofibrillar ATPase ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2001.19930329.x
更新日期：2001-09-01 00:00:00
abstract：:There is need for a consistent definition of structures caudal to the testis that variously are termed 'gubernaculum testis' as a basis for understanding the emergence and sexually dimorphic further growth and differentiation of this specifically mammalian structure. Rodent fetuses undergo a stage of development durin...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-08-01 00:00:00
abstract：:Rodents are defined by a uniquely specialized dentition and a highly complex arrangement of jaw-closing muscles. Finite element analysis (FEA) is an ideal technique to investigate the biomechanical implications of these specializations, but it is essential to understand fully the degree of influence of the different i...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2011.01436.x
更新日期：2011-12-01 00:00:00
abstract：:The rete testis in the domestic fowl (Gallus gallus domesticus), Japanese quail (Coturnix coturnix japonica), guinea-fowl (Numida meleagris galeata) and drake (Anas platyrhynchos) was studied histologically and with both the scanning and transmission electron microscopes. All the birds have rete epithelial cells varyi...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1982-08-01 00:00:00
abstract：:The ultrastructure of the developing fetal lamb myocardium was studied in a series of animals spanning 29 days of gestation to term, and compared with newborn and adult animals. All major ultrastructural features which characterise the adult myocyte were found in early fetal life, although with considerably different ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1983-12-01 00:00:00
abstract：:Facial expressions are a critical mode of non-vocal communication for many mammals, particularly non-human primates. Although chimpanzees (Pan troglodytes) have an elaborate repertoire of facial signals, little is known about the facial expression (i.e. mimetic) musculature underlying these movements, especially when ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2006.00523.x
更新日期：2006-02-01 00:00:00
abstract：:Schwann cells are excluded from the CNS during development by the glial limiting membrane, an area of astrocytic specialisation present at the nerve root transitional zone, and at blood vessels in the neuropil. This barrier, however, can be disrupted and, with the highly migratory nature of Schwann cells, can result i...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1046/j.1469-7580.1997.19010035.x
更新日期：1997-01-01 00:00:00
abstract：:The axolotl Ambystoma mexicanum is one of the most used model organisms in evolutionary, developmental and regenerative studies, particularly because it can reconstitute a fully functional and complete forelimb/hindlimb. Surprisingly, there is no publication that describes all the pectoral and forelimb muscles of this...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2012.01567.x
更新日期：2012-12-01 00:00:00
abstract：:Hair growth in adult mammals involves continuous dermal-epidermal interaction across the follicular basement membrane, and repeated reorganisation of lower follicle structure during the hair growth cycle. The immunolocalisation of 3 extracellular matrix components, fibronectin, laminin and type IV collagen was investi...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
abstract：:Ceratopsidae represents a group of quadrupedal herbivorous dinosaurs that inhabited western North America and eastern Asia during the Late Cretaceous. Although horns and frills of the cranium are highly variable across species, the lower jaw historically has been considered to be relatively conservative in morphology....
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12374
更新日期：2015-11-01 00:00:00
abstract：:A new type of magnetic resonance imaging analysis, based on fusion of three-dimensional reconstructions of time-to-peak parametric maps and high-resolution T1-weighted images, is proposed in order to evaluate the perfusion of selected volumes of interest. Because in recent years a wealth of data have suggested the cru...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2006.00659.x
更新日期：2007-01-01 00:00:00
abstract：:A study has been made of the distribution of granulated metrial gland cells in the non-pregnant uterus, in the pre-implantation uterus and in the post-implantation interconceptual uterus of pregnant albino mice. Granulated cells were only rarely seen in the non-pregnant uterus. In the pre-implantation uterus, they wer...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1981-12-01 00:00:00
abstract：:Angiogenesis is essential for the replacement of cartilage by bone during growth and repair. In order to obtain a better understanding of the mechanisms regulating vascular invasion at sites of endochondral ossification we have investigated the expression of the endothelial cell-specific mitogen, vascular endothelial ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1999.19440519.x
更新日期：1999-05-01 00:00:00
abstract：:The absolute number of parvicellular and magnocellular neurons in the red nucleus was estimated using design-based stereological counting methods and systematic random sampling techniques. Six young adult male rats, and a complete set of serial 40-μm glycolmethacrylate sections for each rat, were used to quantify neur...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12495
更新日期：2016-09-01 00:00:00
