Diversity and structure of PIF/Harbinger-like elements in the genome of Medicago truncatula.

abstract：BACKGROUND:Cadmium (Cd) is a serious heavy metal (HM) soil pollutant. To alleviate or even eliminate HM pollution in soil, environmental-friendly methods are applied. One is that special plants are cultivated to absorb the HM in the contaminated soil. As an excellent economical plant with ornamental value and sound ada...

journal_title：BMC genomics

authors： Wang MQ,Bai ZY,Xiao YF,Li Y,Liu QL,Zhang L,Pan YZ,Jiang BB,Zhang F

更新日期：2019-11-20 00:00:00

abstract：BACKGROUND:Allelic variation is the cornerstone of genetically determined differences in gene expression, gene product structure, physiology, and behavior. However, allelic variation, particularly cryptic (unknown or not annotated) variation, is problematic for follow up analyses. Polymorphisms result in a high inciden...

journal_title：BMC genomics

authors： Walter NA,Bottomly D,Laderas T,Mooney MA,Darakjian P,Searles RP,Harrington CA,McWeeney SK,Hitzemann R,Buck KJ

更新日期：2009-08-17 00:00:00

abstract：BACKGROUND:The transformation of a developing epithelium into an adult structure is a complex process, which often involves coordinated changes in cell proliferation, metabolism, adhesion, and shape. To identify genetic mechanisms that control epithelial differentiation, we analyzed the temporal patterns of gene expres...

journal_title：BMC genomics

authors： O'Keefe DD,Thomas SR,Bolin K,Griggs E,Edgar BA,Buttitta LA

更新日期：2012-09-20 00:00:00

abstract：BACKGROUND:Aluminium (Al) toxicity is the main factor limiting the crop production in acid soils and barley (Hordeum vulgare L.) is one of the most Al-sensitive of the small-grained cereals. The major gene for Al tolerance in barley is HvAACT1 (HvMATE) on chromosome 4H which encodes a multidrug and toxic compound extru...

journal_title：BMC genomics

authors： Ma Y,Li C,Ryan PR,Shabala S,You J,Liu J,Liu C,Zhou M

更新日期：2016-03-05 00:00:00

abstract：BACKGROUND:Regions of the genome that are under evolutionary constraint across multiple species have previously been used to identify functional sequences in the human genome. Furthermore, it is known that there is an inverse relationship between evolutionary constraint and the allele frequency of a mutation segregatin...

journal_title：BMC genomics

authors： Hodgkinson A,Casals F,Idaghdour Y,Grenier JC,Hernandez RD,Awadalla P

更新日期：2013-07-23 00:00:00

abstract：BACKGROUND:Biocontrol of bacterial pathogens by bacteriophages (phages) represents a promising strategy. Vibrio alginolyticus, a gram-negative bacterium, is a notorious pathogen responsible for the loss of economically important farmed marine animals. To date, few V. alginolyticus phages have been successfully isolated...

journal_title：BMC genomics

authors： Luo P,Yun L,Li Y,Tian Y,Liu Q,Huang W,Hu C

更新日期：2018-10-11 00:00:00

abstract：BACKGROUND:The expanding number and global distributions of herbicide resistant weedy species threaten food, fuel, fiber and bioproduct sustainability and agroecosystem longevity. Amongst the most competitive weeds, Amaranthus palmeri S. Wats has rapidly evolved resistance to glyphosate primarily through massive amplif...

journal_title：BMC genomics

authors： Molin WT,Wright AA,Lawton-Rauh A,Saski CA

更新日期：2017-01-17 00:00:00

abstract：BACKGROUND:Epidermal Growth Factor (EGF) is a key regulatory growth factor activating many processes relevant to normal development and disease, affecting cell proliferation and survival. Here we use a combined approach to study the EGF dependent transcriptome of HeLa cells by using multiple long oligonucleotide based ...

journal_title：BMC genomics

authors： Llorens F,Hummel M,Pastor X,Ferrer A,Pluvinet R,Vivancos A,Castillo E,Iraola S,Mosquera AM,González E,Lozano J,Ingham M,Dohm JC,Noguera M,Kofler R,del Río JA,Bayés M,Himmelbauer H,Sumoy L

更新日期：2011-06-23 00:00:00

abstract：BACKGROUND:The numerous classes of repeats often impede the assembly of genome sequences from the short reads provided by new sequencing technologies. We demonstrate a simple and rapid means to ascertain the repeat structure and total size of a bacterial or archaeal genome without the need for assembly by directly anal...

journal_title：BMC genomics

authors： Williams D,Trimble WL,Shilts M,Meyer F,Ochman H

更新日期：2013-08-08 00:00:00

abstract：BACKGROUND:Understanding the evolution of the vertebrate pancreas is key to understanding its functions. The chondrichthyes (cartilaginous fish such as sharks and rays) have often been suggested to possess the most ancient example of a distinct pancreas with both hormonal (endocrine) and digestive (exocrine) roles. The...

journal_title：BMC genomics

authors： Mulley JF,Hargreaves AD,Hegarty MJ,Heller RS,Swain MT

更新日期：2014-12-06 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) exist pervasively across viruses, plants and animals and play important roles in the post-transcriptional regulation of genes. In the common carp, miRNA targets have not been investigated. In model species, single-nucleotide polymorphisms (SNPs) have been reported to impair or enhance miRN...

journal_title：BMC genomics

authors： Zhu YP,Xue W,Wang JT,Wan YM,Wang SL,Xu P,Zhang Y,Li JT,Sun XW

更新日期：2012-08-21 00:00:00

abstract：BACKGROUND:Previous studies show that galanin neurons in ventrolateral preoptic nucleus (VLPO-Gal) are essential for sleep regulation. Here, we explored the transcriptional regulation of the VLPO-Gal neurons in sleep by comparing their transcriptional responses between sleeping mice and those kept awake, sacrificed at ...

journal_title：BMC genomics

authors： Guo X,Gao X,Keenan BT,Zhu J,Sarantopoulou D,Lian J,Galante RJ,Grant GR,Pack AI

更新日期：2020-09-14 00:00:00

abstract：BACKGROUND:Currently, diabetes has become one of the leading causes of death worldwide. Fasting plasma glucose (FPG) levels that are higher than optimal, even if below the diagnostic threshold of diabetes, can also lead to increased morbidity and mortality. Here we intend to study the magnitude of the genetic influence...

journal_title：BMC genomics

authors： Wang W,Zhang C,Liu H,Xu C,Duan H,Tian X,Zhang D

更新日期：2020-07-18 00:00:00

abstract：BACKGROUND:Domestic broiler chickens rapidly accumulate adipose tissue due to intensive genetic selection for rapid growth and are naturally hyperglycemic and insulin resistant, making them an attractive addition to the suite of rodent models used for studies of obesity and type 2 diabetes in humans. Furthermore, chick...

journal_title：BMC genomics

authors： Ji B,Ernest B,Gooding JR,Das S,Saxton AM,Simon J,Dupont J,Métayer-Coustard S,Campagna SR,Voy BH

更新日期：2012-08-31 00:00:00

abstract：BACKGROUND:Nicotiana attenuata (coyote tobacco) is an ecological model for studying plant-environment interactions and plant gene function under real-world conditions. During the last decade, large amounts of genomic, transcriptomic and metabolomic data have been generated with this plant which has provided new insight...

journal_title：BMC genomics

authors： Brockmöller T,Ling Z,Li D,Gaquerel E,Baldwin IT,Xu S

更新日期：2017-01-13 00:00:00

abstract：BACKGROUND:Sensory hair cells are exquisitely sensitive to mechanical stimuli and as such, are prone to damage and apoptosis during dissections or in vitro manipulations. Thiouracil (TU)-tagging is a noninvasive method to label cell type-specific transcripts in an intact organism, thereby meeting the challenge of how t...

journal_title：BMC genomics

authors： Erickson T,Nicolson T

更新日期：2015-10-23 00:00:00

abstract：BACKGROUND:The preferred habitat of a given bacterium can provide a hint of which types of enzymes of potential industrial interest it might produce. These might include enzymes that are stable and active at very high or very low temperatures. Being able to accurately predict this based on a genomic sequence, would thu...

journal_title：BMC genomics

authors： Jensen DB,Vesth TC,Hallin PF,Pedersen AG,Ussery DW

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The golden birdwing butterfly (Troides aeacus formosanus) is a rarely observed species in Taiwan. Recently, a typical symptom of nuclear polyhedrosis was found in reared T. aeacus larvae. From the previous Kimura-2 parameter (K-2-P) analysis based on the nucleotide sequence of three genes in this isolate, po...

journal_title：BMC genomics

authors： Huang YF,Chen TH,Chang ZT,Wang TC,Lee SJ,Kim JC,Kim JS,Chiu KP,Nai YS

更新日期：2019-05-27 00:00:00

abstract：BACKGROUND:The P1B-ATPase subfamily is an important group involved in transporting heavy metals and has been extensively studied in model plants, such as Arabidopsis thaliana and Oryza sativa. Emerging evidence indicates that one homolog in Glycine max is also involved in cadmium (Cd) stress, but the gene family has no...

journal_title：BMC genomics

authors： Fang X,Wang L,Deng X,Wang P,Ma Q,Nian H,Wang Y,Yang C

更新日期：2016-05-20 00:00:00

abstract：BACKGROUND:Genetic admixture is a common caveat for genetic association analysis. Therefore, it is important to characterize the genetic structure of the population under study to control for this kind of potential bias. RESULTS:In this study we have sampled over 800 unrelated individuals from the population of Spain,...

journal_title：BMC genomics

authors： Gayán J,Galan JJ,González-Pérez A,Sáez ME,Martínez-Larrad MT,Zabena C,Rivero MC,Salinas A,Ramírez-Lorca R,Morón FJ,Royo JL,Moreno-Rey C,Velasco J,Carrasco JM,Molero E,Ochoa C,Ochoa MD,Gutiérrez M,Reina M,Pascual R,

更新日期：2010-05-25 00:00:00

abstract：BACKGROUND:Chinese wild grapevine (Vitis amurensis) has remarkable cold stress tolerance, exceeding that of the common cultivated grapevine (Vitis vinifera L.). RESULT:Here, we surveyed the expression dynamics of microRNAs (miRNAs) across Chinese wild grapevine (cv. Beibinghong) and cultivated grapevine (cv. Cabernet ...

journal_title：BMC genomics

authors： Wang P,Yang Y,Shi H,Wang Y,Ren F

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:Parasites employ proteases to evade host immune systems, feed and replicate and are often the target of anti-parasite strategies to disrupt these interactions. Myxozoans are obligate cnidarian parasites, alternating between invertebrate and fish hosts. Their genes are highly divergent from other metazoans, a...

journal_title：BMC genomics

authors： Hartigan A,Kosakyan A,Pecková H,Eszterbauer E,Holzer AS

更新日期：2020-06-16 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are a large family of endogenous, non-coding RNAs, about 22 nucleotides long, which regulate gene expression through sequence-specific base pairing with target mRNAs. Extensive studies have shown that miRNA expression in the skin changes remarkably during distinct stages of the hair cycle ...

journal_title：BMC genomics

authors： Yuan C,Wang X,Geng R,He X,Qu L,Chen Y

更新日期：2013-07-28 00:00:00

abstract：BACKGROUND:RNA amplification is necessary for profiling gene expression from small tissue samples. Previous studies have shown that the T7 based amplification techniques are reproducible but may distort the true abundance of targets. However, the consequences of such distortions on the ability to detect biological vari...

journal_title：BMC genomics

authors： Diboun I,Wernisch L,Orengo CA,Koltzenburg M

更新日期：2006-10-09 00:00:00

abstract：BACKGROUND:Venomous animals incapacitate their prey using complex venoms that can contain hundreds of unique protein toxins. The realisation that many of these toxins may have pharmaceutical and insecticidal potential due to their remarkable potency and selectivity against target receptors has led to an explosion in th...

journal_title：BMC genomics

authors： Wood DL,Miljenović T,Cai S,Raven RJ,Kaas Q,Escoubas P,Herzig V,Wilson D,King GF

更新日期：2009-08-13 00:00:00

abstract：BACKGROUND:Mitochondrial genomes comprise a small but critical component of the total DNA in eukaryotic organisms. They encode several key proteins for the cell's major energy producing apparatus, the mitochondrial respiratory chain. Additionally, their nucleotide and amino acid sequences are of great utility as marker...

journal_title：BMC genomics

authors： Lloyd RE,Foster PG,Guille M,Littlewood DT

更新日期：2012-09-19 00:00:00

abstract：BACKGROUND:The ubiquitin-conjugating enzyme HR6B is required for spermatogenesis in mouse. Loss of HR6B results in aberrant histone modification patterns on the trancriptionally silenced X and Y chromosomes (XY body) and on centromeric chromatin in meiotic prophase. We studied the relationship between these chromatin m...

journal_title：BMC genomics

authors： Mulugeta Achame E,Wassenaar E,Hoogerbrugge JW,Sleddens-Linkels E,Ooms M,Sun ZW,van IJcken WF,Grootegoed JA,Baarends WM

更新日期：2010-06-10 00:00:00

abstract：BACKGROUND:Age-related gene expression patterns of Homo sapiens as well as of model organisms such as Mus musculus, Saccharomyces cerevisiae, Caenorhabditis elegans and Drosophila melanogaster are a basis for understanding the genetic mechanisms of ageing. For an effective analysis and interpretation of expression prof...

journal_title：BMC genomics

authors： Hofer E,Laschober GT,Hackl M,Thallinger GG,Lepperdinger G,Grillari J,Jansen-Dürr P,Trajanoski Z

更新日期：2011-05-24 00:00:00

abstract：BACKGROUND:Although numerous investigations have compared gene expression microarray platforms, preprocessing methods and batch correction algorithms using constructed spike-in or dilution datasets, there remains a paucity of studies examining the properties of microarray data using diverse biological samples. Most mic...

journal_title：BMC genomics

authors： Richard AC,Lyons PA,Peters JE,Biasci D,Flint SM,Lee JC,McKinney EF,Siegel RM,Smith KG

更新日期：2014-08-04 00:00:00

abstract：BACKGROUND:Based on sequence similarity, the superfamily of G protein-coupled receptors (GPRs) can be subdivided into several subfamilies, the members of which often share similar ligands. The sequence data provided by the human genome project allows us to identify new GPRs by in silico homology screening, and to predi...

journal_title：BMC genomics

authors： Wittenberger T,Hellebrand S,Munck A,Kreienkamp HJ,Schaller HC,Hampe W

更新日期：2002-07-05 00:00:00