Abstract：
:Polystyrene-polyisocyanopeptide (PS-PIAT) polymersomes containing CALB in two different locations, one in the aqueous inner compartment and one in the bilayer, were investigated for enzymatic ring-opening polymerization of lactones in water. It is shown that the monomers 8-octanolactone and dodecalactone yield oligomers with this polymersome system. It is also observed that the polymerization activity is dependent on the position of the enzyme in the polymersome. SEM investigations show that the polymersome structures were destabilized during the polymerization. Further investigations show that the vesicular morphology of the polymersomes was destabilized only in the case of polymer product formation.
journal_name
Biomacromoleculesjournal_title
Biomacromoleculesauthors
Nallani M,de Hoog HP,Cornelissen JJ,Palmans AR,van Hest JC,Nolte RJdoi
10.1021/bm7005938subject
Has Abstractpub_date
2007-12-01 00:00:00pages
3723-8issue
12eissn
1525-7797issn
1526-4602journal_volume
8pub_type
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