Abstract:
:Pediatric medicine is moving toward a greater appreciation that the delivery of quality medical care involves a partnership including the health care team, the child, and the family. Pediatric medicine now emphasizes the importance of information exchange among these groups. This paper discusses two models for communicating with children and their families throughout a complex life-threatening illness. Both models serve as a framework for integrating the medical and nonmedical aspects of the illness experience.
journal_name
Curr Oncol Repjournal_title
Current oncology reportsauthors
Weidner NJdoi
10.1007/s11912-007-0061-9subject
Has Abstractpub_date
2007-11-01 00:00:00pages
437-9issue
6eissn
1523-3790issn
1534-6269journal_volume
9pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:Improved management of infectious complications of acute myeloid leukemia (AML) has contributed substantially to the success of care over the past half century. An important approach to reducing infectious complications during the induction period of chemotherapy involves the use of prophylactic antib...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-017-0574-9
更新日期:2017-03-01 00:00:00
abstract::Proton beam radiation therapy (PBRT) has unique physical properties (e.g., Bragg Peak) that limit the amount of normal tissue irradiated in the head and neck region while maximizing the radiation delivered to the tumor. Radiation therapy is commonly used in both the primary and adjuvant setting for many head and neck ...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-010-0089-0
更新日期:2010-05-01 00:00:00
abstract::Prostate cancer is the most common cancer and the second leading cause of cancer-related deaths in American men. Although the use of the prostate-specific antigen (PSA) test for prostate cancer screening since the 1990s has led to increased early diagnoses, the most recent studies are in conflict about the risks and b...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-010-0136-x
更新日期:2011-02-01 00:00:00
abstract::Most of the experience with second-line chemotherapy for non-small-cell lung cancer (NSCLC) comes from small phase II trials, which have shown disappointing or inconsistent results. The notable exception has been docetaxel, which has been extensively studied as a second-line therapy for NSCLC. On the basis of consiste...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-000-0016-x
更新日期:2000-01-01 00:00:00
abstract::Acute promyelocytic leukemia (APL) is a disease associated with fusion oncoproteins invariably involving the retinoic acid receptor (Raralpha). Retinoic acid induces differentiation in APL cells and is successfully used in conjunction with chemotherapy to treat and cure a significant percentage of patients with APL. A...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-001-0052-1
更新日期:2001-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Older adults with cancer have complex medical needs and often experience higher rates of treatment-related toxicities compared to their younger counterparts. The advent of health information technologies can address multiple gaps in the care of this population. We review the role of existing and emerg...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-018-0672-3
更新日期:2018-03-06 00:00:00
abstract::Neuroblastoma is the most common extracranial tumor of childhood, with about 650 new cases each year in the United States. The clinical course of neuroblastoma is variable and depends on age at diagnosis, staging, histology, and specific genetic abnormalities, such as MYCN oncogene amplification or aberrations of chro...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-009-0059-6
更新日期:2009-11-01 00:00:00
abstract:PURPOSE OF REVIEW:The calculation of noncancer-specific life expectancy can guide shared decision-making and avoid over- and undertreatment in older adults with cancer. Several factors determine life expectancy, including socio-demographic background, comorbidities, physical performance, and geriatric assessment variab...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-019-0821-3
更新日期:2019-06-25 00:00:00
abstract::The utility of lymphatic mapping and sentinel lymph node biopsy in malignancies of the female lower genital tract-- vulvar, vaginal, and cervical cancers--is being explored in multiple centers internationally. For patients with these tumors, lymphatic mapping with sentinel lymph node biopsy holds the promise of increa...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-005-0008-y
更新日期:2005-11-01 00:00:00
abstract::Primary intraocular lymphoma (PIOL) is a subset of primary central nervous system lymphoma (PCNSL) in which malignant lymphoid cells invade the retina, vitreous body, or optic nerve head. It is usually a large B-cell non-Hodgkin's lymphoma. PIOL typically presents as a vitritis that is unresponsive to corticosteroid t...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-005-0029-6
更新日期:2005-01-01 00:00:00
abstract::The prodrug strategy has its own particular real and theoretic obstacles. Clinical strategies and research efforts have tried to approach these problems. The bystander effect, whereby nontransduced cells are affected by simple proximity to those that have received the novel gene, has enabled many prodrug systems to be...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-000-0006-z
更新日期:2000-01-01 00:00:00
abstract::The treatment of non-Hodgkin lymphoma (NHL) has changed dramatically since the introduction of rituximab, a monoclonal antibody that binds to the B-cell transmembrane protein CD20 and causes lysis of the lymphoma cells. Since then, a number of additional antibodies have been tested against other B-cell targets, result...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-008-0064-1
更新日期:2008-09-01 00:00:00
abstract::Chemotherapy was traditionally perceived to be ineffective for prostate cancer and was only administered to patients with symptomatic hormone-refractory disease. Although previous reviews have confirmed this belief, recent studies have demonstrated significant antitumor activity with chemotherapy regimens. This articl...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-003-0114-7
更新日期:2003-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Mantle cell lymphoma (MCL) prognosis is strictly related to the characteristics of the disease, which can range from very indolent cases to highly aggressive and refractory ones. Here we will review the current knowledge on MCL biomarkers. RECENT FINDINGS:Biomarker-informed diagnosis is essential for...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-018-0728-4
更新日期:2018-08-22 00:00:00
abstract::Mutations in the cancer susceptibility genes BRCA1 and BRCA2 are associated with significantly increased risks of breast and ovarian cancer. Fortunately, effective strategies are available to reduce these risks, including genetic testing, which is an important consideration in determining management of patients with a...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-008-0008-9
更新日期:2008-01-01 00:00:00
abstract::The introduction of targeted therapies, specifically those that target the VEGF receptor (VEGFR), PDGF receptor (PDGFR) and the mTOR pathways, has significantly changed the approach to patients with unresectable renal cell cancer (RCC). However, drug resistance develops through bypassing of targeted pathways. Regorafe...
journal_title:Current oncology reports
pub_type: 杂志文章
doi:10.1007/s11912-013-0292-x
更新日期:2013-04-01 00:00:00
abstract::Glioblastoma multiforme (GBM) is the most common central nervous system malignancy. It is rapidly progressive with rare opportunity for cure. After three decades of laboratory and clinical research, a newly evolved chemoradiotherapy approach using the alkylating agent temozolomide during and after radiotherapy has res...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/BF02951428
更新日期:2007-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this article is to discuss the current role of radiotherapy (RT) for early-stage Hodgkin's lymphoma (HL) in the context of risk-adapted and response-adapted treatment strategy, and describe changes in RT technical approach. RECENT FINDINGS:In low-risk patients, RT could be omitted but, at ...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-017-0592-7
更新日期:2017-05-01 00:00:00
abstract::The evolution of our ability to diagnose and classify lymphomas in an increasingly refined manner has paralleled the development of novel technologic approaches, with contemporary practice dependent upon the harnessing of a plethora of data that include microscopic, immunophenotypic, and genetic information. Although ...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-004-0063-9
更新日期:2004-09-01 00:00:00
abstract::The establishment of the Intergroup Rhabdomyosarcoma Study (IRS) Committee in 1972 by three extant American pediatric cooperative groups initiated five generations of studies in the multidisciplinary treatment of soft-tissue sarcomas. Taking the lead from the use of vincristine, actinomycin-D, and cyclophosphamide (VA...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-003-0012-z
更新日期:2003-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Despite recent advances in the care of patients with advanced non-small cell lung cancer (NSCLC), significant morbidity and mortality remains. Symptoms caused by the cancer and its treatments can be profoundly debilitating. Palliative care aims to reduce this burden. In this review, we discuss the def...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-018-0731-9
更新日期:2018-11-09 00:00:00
abstract:PURPOSE OF REVIEW:Management of metastatic head and neck squamous cell cancers (HNSCC) can be challenging. This review gives an insight of current treatment options for patients with synchronous metastatic HNSCC and suggests a therapeutic algorithm. RECENT FINDINGS:With the rise of novel therapeutic techniques and med...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-019-0856-5
更新日期:2019-11-14 00:00:00
abstract:PURPOSE OF REVIEW:Medical decisions concerning active surveillance are complex, especially when evidence on superiority of one of the treatments is lacking. Decision aids have been developed to facilitate shared decision-making on whether to pursue an active surveillance strategy. However, it is unclear how these decis...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-020-00962-3
更新日期:2020-07-28 00:00:00
abstract:PURPOSE OF REVIEW:The American Society of Clinical Oncology (ASCO) palliative care recommendations have been updated into a full guideline. Symptom questionnaires-completed and reviewed with patients during care delivery-are poised to play a large role in this guideline because they provide a more comprehensive underst...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-017-0571-z
更新日期:2017-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Skull base reirradiation is challenging due to complex anatomy, enrichment of treatment-resistant clonogens, and increased risk of severe treatment complications. Without local therapy, early mortality is certain and tumor progression can result in debilitating symptoms. Modern radiotherapy advancemen...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-017-0639-9
更新日期:2017-10-28 00:00:00
abstract::The original version of this article, which published in Current Oncology Reports, Volume 21, Issue 6, June 2019, contained an error in addressing the indication for use of neratinib in early stage breast cancer. ...
journal_title:Current oncology reports
pub_type: 已发布勘误
doi:10.1007/s11912-019-0813-3
更新日期:2019-05-17 00:00:00
abstract:PURPOSE OF REVIEW:Surgical management of locally advanced oral cavity squamous cell carcinomas (OCSCC) has long been recognized as a primary treatment modality. Technological advances have led to significant improvements in our surgical approach, from improvement in the visualization of tumors to more efficient and pre...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-019-0845-8
更新日期:2019-11-07 00:00:00
abstract::The topoisomerase I inhibitors such as irinotecan and topotecan are active agents against small-cell lung cancer that are effective in treating not only chemotherapy-naïve tumors but also progressed-stage tumors after treatment with cisplatin-based regimens, because their mechanism of antitumor activity differs from t...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-001-0018-3
更新日期:2001-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The concept of value-based health care (VBHC) was articulated more than a decade ago. However, its clinical implementation remains an on-going process and a particularly demanding one for the domain of head and neck cancer (HNC). These cancers often present with fast growing tumors in functionally and...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-020-00952-5
更新日期:2020-07-10 00:00:00
abstract:PURPOSE OF REVIEW:This review was undertaken to analyze the main reasons behind the limited development of hospice care in China, and to put forward some suggestions. RECENT FINDINGS:Although the Chinese government has increased its support for hospice care in recent years, however, owing to the lack of education arou...
journal_title:Current oncology reports
pub_type: 杂志文章,评审
doi:10.1007/s11912-020-00959-y
更新日期:2020-07-28 00:00:00