Apomorphine therapy in Parkinson's disease: a review.

abstract：OBJECTIVE:The study investigated the efficacy and tolerability of teneligliptin co-administered to patients with type 2 diabetes mellitus (T2DM) who were inadequately controlled by stable metformin monotherapy ≥ 1000 mg/day. METHODS:A total of 447 patients from 55 European centers who completed a 14-day screening and ...

journal_title：Expert opinion on pharmacotherapy

authors： Bryson A,Jennings PE,Deak L,Paveliu FS,Lawson M

更新日期：2016-07-01 00:00:00

abstract：INTRODUCTION:When estimating the cost-effectiveness or budget impact of chronic obstructive pulmonary disease (COPD) medication, it is common practice to use trial data for clinical inputs. However, such inputs do not always reflect the real-world situation. Previous reviews recognized the need for taking real-world da...

journal_title：Expert opinion on pharmacotherapy

authors： Fens T,Zhou G,Postma MJ,van Puijenbroek EP,van Boven JFM

更新日期：2021-01-13 00:00:00

abstract：BACKGROUND:Fampridine-SR is under submission as the first drug to be FDA approved with an indication specifically for multiple sclerosis symptoms. Compounded forms of the active agent of Fampridine-SR (4-aminopyridine) have been used in clinical practice for many years. Clinical trials have now been completed that demo...

journal_title：Expert opinion on pharmacotherapy

authors： Kachuck NJ

更新日期：2009-08-01 00:00:00

abstract：INTRODUCTION:Myoclonic seizures are brief, involuntary muscular jerks arising from the central nervous system that can occur in different epilepsy syndromes, including idiopathic generalized epilepsies or the most severe group of epileptic encephalopathies. Valproate is commonly the first choice alone or in combination...

journal_title：Expert opinion on pharmacotherapy

authors： Striano P,Belcastro V

更新日期：2017-02-01 00:00:00

abstract：INTRODUCTION:Asthma is the most common chronic disease in childhood, affecting approximately 10% of all children, and is the leading cause of hospitalization in developed countries. In this paper we aimed to review the evidence on chemical pharmacotherapy for long-term treatment of pediatric asthma, according to the la...

journal_title：Expert opinion on pharmacotherapy

authors： Vitale C,Maglio A,Pelaia C,Vatrella A

更新日期：2017-05-01 00:00:00

abstract：:Introduction: Hypertrophic cardiomyopathy (HCM) is one of the most common genetic heart diseases and represents a leading cause of sudden cardiac death as well as a prevalent cause of heart failure and stroke. HCM is characterized by a very complex pathophysiology, consisting of heterogeneous clinical manifestations a...

journal_title：Expert opinion on pharmacotherapy

authors： Spoladore R,Fragasso G,Pannone L,Slavich M,Margonato A

更新日期：2020-02-01 00:00:00

abstract：INTRODUCTION:Cardiovascular disease is a major cause of death, and hypercholesterolemia is a major risk factor. Statins, with simvastatin among the most widely used, have ample evidence demonstrating prevention of cardiovascular events and mortality. Ezetimibe is effective at improving serum lipids in combination with ...

journal_title：Expert opinion on pharmacotherapy

authors： Gryn SE,Hegele RA

更新日期：2015-06-01 00:00:00

abstract：INTRODUCTION:The pharmacotherapeutic management of depression in patients with multiple sclerosis (MS) is a matter of debate that cannot be decided from the evidence available in the current literature. Therefore, its management essentially relies on the clinical experience of the prescribing clinician rather than on e...

journal_title：Expert opinion on pharmacotherapy

authors： Carta MG,Paribello P,Anastasia A,De Berardis D,Nardi AE,Fornaro M

更新日期：2018-10-01 00:00:00

abstract：INTRODUCTION:Despite its frequency, recognition and therapy of vulvovaginal atrophy (VVA) remain suboptimal. Wet mount microscopy, or vaginal pH as a proxy, allows VVA diagnosis in menopause, but also in young contraception users, after breast cancer, or postpartum. Intravaginal low dose estrogen product is the main th...

journal_title：Expert opinion on pharmacotherapy

authors： Donders GGG,Ruban K,Bellen G,Grinceviciene S

更新日期：2019-05-01 00:00:00

abstract：:Seborrhoeic dermatitis (SD) is a recurrent, chronic inflammation of the skin that occurs on sebum rich areas such as the face, scalp and chest, characterised by red scaly lesions. The are many studies indicating that Malassezia yeasts play an important role in the aetiology of this condition, most of the evidence for ...

journal_title：Expert opinion on pharmacotherapy

authors： Gupta AK,Kogan N

更新日期：2004-08-01 00:00:00

abstract：INTRODUCTION:Hyperphosphataemia is common in chronic kidney disease (CKD), particularly in the late stages and is associated with secondary hyperparathyroidism, abnormal bone mineralisation and increased cardiovascular morbidity/mortality. At present, there is a range of phosphate binders designed to keep serum phospha...

journal_title：Expert opinion on pharmacotherapy

authors： Locatelli F,Dimkovic N,Spasovski G

更新日期：2014-07-01 00:00:00

abstract：IMPORTANCE OF THE FIELD:The emergence of fixed-combination drugs for the treatment of glaucoma has, to some extent, changed the medical management of glaucoma. The potential benefits of these drugs include a reduction in the total number of drops and preservatives instilled per day and improved patient comfort factors,...

journal_title：Expert opinion on pharmacotherapy

authors： Razeghinejad MR,Sawchyn AK,Katz LJ

更新日期：2010-04-01 00:00:00

abstract：:Maximal surgical debulking and radiotherapy have been the cornerstone of therapy for high-grade gliomas. The impact of chemotherapy on outcome has been marginal and, until recently, its usage has been debatable. The development of new drugs and an improved understanding of chemoresistance have reinvigorated interest i...

journal_title：Expert opinion on pharmacotherapy

authors： Cavaliere R,Newton H

更新日期：2006-04-01 00:00:00

abstract：INTRODUCTION:Convulsive status epilepticus (SE) is one of the most frequent and severe neurological emergencies in both adults and children. A timely administration of appropriate antiepileptic drugs (AEDs) can stop seizures early and markedly improve outcome. AREAS COVERED:The main treatment strategies for SE are rev...

journal_title：Expert opinion on pharmacotherapy

authors： Sánchez Fernández I,Loddenkemper T

更新日期：2015-03-01 00:00:00

abstract：:One vaccine designed to prevent cancer by preventing a precursor infection is already in common use, and at least one more is in the latter stages of clinical development. These vaccines are part of a new era of cancer immunoprophylaxis. Several further vaccines are in preclinical and clinical development, targeted at...

journal_title：Expert opinion on pharmacotherapy

authors： Frazer I

更新日期：2004-12-01 00:00:00

abstract：:Diabetes mellitus has reached epidemic proportions in many countries and is the most common cause of end stage renal disease (ESRD). The angiotensin II receptor-1 (AT(1)) antagonists losartan and irbesartan have recently been evaluated as renoprotective agents in large clinical trials of patients with Type 2 diabetes ...

journal_title：Expert opinion on pharmacotherapy

authors： Doggrell SA

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:To explore the treatment response, tolerability and safety of once-monthly paliperidone palmitate (PP1M) in non-acute patients switched from oral antipsychotics, stratified by time since diagnosis as recently diagnosed (≤3 years) or chronic patients (>3 years). RESEARCH DESIGN AND METHODS:Post hoc analysis o...

journal_title：Expert opinion on pharmacotherapy

authors： Hargarter L,Bergmans P,Cherubin P,Keim S,Conca A,Serrano-Blanco A,Bitter I,Bilanakis N,Schreiner A

更新日期：2016-06-01 00:00:00

abstract：:Somatropin (rDNA origin) injection (Zorbtive) is a highly purified preparation of human growth hormone (GH) produced from a mammalian cell line by recombinant DNA technology. It is the only human GH approved for the treatment of short bowel syndrome in patients receiving specialised nutritional support. The process of...

journal_title：Expert opinion on pharmacotherapy

authors： Matarese LE,Abu-Elmagd K

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Dexmethylphenidate is a single-isomer stimulant medication approved for the treatment of attention deficit hyperactivity disorder (ADHD). Single-isomer drugs have the potential for decreased undesired effects and improved therapeutic efficacy. Stimulant medications have been the mainstay treatments for ADHD ...

journal_title：Expert opinion on pharmacotherapy

authors： Coury D

更新日期：2009-11-01 00:00:00

abstract：INTRODUCTION:Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune condition traditionally viewed as a severe destructive disease affecting physical health and global wellbeing. The treatment strategies for RA have changed in the last decades from mainly symptomatic towards a more vigorous and targeted approac...

journal_title：Expert opinion on pharmacotherapy

authors： De Cock D,Van der Elst K,Meyfroidt S,Verschueren P,Westhovens R

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:In this review, the authors describe medications in phase III of clinical development for schizophrenia and schizoaffective disorder, and provide an opinion on how current treatment can be improved in the near future. AREAS COVERED:Recent (post 2013) phase III clinical trials of schizophrenia-targeted the...

journal_title：Expert opinion on pharmacotherapy

authors： Garay RP,Citrome L,Samalin L,Liu CC,Thomsen MS,Correll CU,Hameg A,Llorca PM

更新日期：2016-01-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is a rare disease characterized by the accumulation of clonal dendritic cells in different organs. Most recent findings (e.g., activating BRAF mutations) favor the hypothesis that LCH may represent a neoplasm with varying behavior, but the ultimate pathogenesis remains to be uncover...

journal_title：Expert opinion on pharmacotherapy

authors： Minkov M

更新日期：2012-08-01 00:00:00

abstract：INTRODUCTION:Short bowel syndrome (SBS) has traditionally been regarded as a rapidly fatal medical catastrophe. The advent of pharmacological options directly targeting disease pathophysiology justified this review. AREAS COVERED:Since the 1970s, home parenteral nutrition has reduced mortality, converting SBS into a c...

journal_title：Expert opinion on pharmacotherapy

authors： Hollanda Martins Da Rocha M,Lee ADW,Marin MLM,Faintuch S,Mishaly A,Faintuch J

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Skin and skin structure infections are frequently encountered in clinical practice. Fortunately, these infections usually produce only mild to moderate symptoms and signs. Some, however, are severe and may even be life-threatening. OBJECTIVE:To review the approach to the evaluation and treatment of patients...

journal_title：Expert opinion on pharmacotherapy

authors： Cornia PB,Davidson HL,Lipsky BA

更新日期：2008-04-01 00:00:00

abstract：:This is a review of the literature comparing the efficacy and safety of drug-eluting stents (DES) versus bare-metal stents (BMS) in patients with acute myocardial infarction (MI). The present article reviews whether DES are beneficial in the setting of primary percutaneous coronary intervention (PCI), and this has bee...

journal_title：Expert opinion on pharmacotherapy

authors： Yeter E,Kurt M,Silay Y,Anderson HV,Denktas AE

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Treatment of complicated intra-abdominal infections (cIAIs) is becoming increasingly difficult because of the widespread emergence of multidrug-resistant organisms. AREAS COVERED:In this review, we discuss the effectiveness of several new antibiotics for the treatment of cIAIs, including new β-lactamase i...

journal_title：Expert opinion on pharmacotherapy

authors： Lin SY,Huang CH,Ko WC,Chen YH,Hsueh PR

更新日期：2016-01-01 00:00:00

abstract：:Therapy of hepatitis C virus (HCV) infection may prevent progression to cirrhosis, hepatocellular carcinoma and end-stage liver disease. The cornerstone of treatment has long been standard IFN-alpha, the use of which was associated with a sustained biochemical and viral response in only a small proportion of patients....

journal_title：Expert opinion on pharmacotherapy

authors： Toniutto P,Fabris C,Pirisi M

更新日期：2006-10-01 00:00:00

abstract：:Motor fluctuations are a common problem in the long-term management of Parkinson's disease (PD), resulting in disability and impaired quality of life. The relatively short serum half-life (approximately 90 min) of oral levodopa/carbidopa and its erratic absorption due to delayed and inconsistent gastric emptying (a no...

journal_title：Expert opinion on pharmacotherapy

authors： Samanta J,Hauser RA

更新日期：2007-04-01 00:00:00

abstract：:The aim of this review is to provide a rationale for evaluating thiazolidinediones (TZDs) as putative treatments for cognitive deficits in individuals with mood disorders. A MedLine search of all English-language articles published between January 1966 and August 2006 was conducted. The search terms were: the non-prop...

journal_title：Expert opinion on pharmacotherapy

authors： McIntyre RS,Soczynska JK,Woldeyohannes HO,Lewis GF,Leiter LA,MacQueen GM,Miranda A,Fulgosi D,Konarski JZ,Kennedy SH

更新日期：2007-08-01 00:00:00

abstract：:Synovitis is a painful and, occasionally, disabling disease. Patients with synovitis, especially new onset synovitis, should be referred to a rheumatologist urgently so that they can be assed and treated as quickly as possible. Clinical assessment and investigations are required to help differentiate between transient...

journal_title：Expert opinion on pharmacotherapy

authors： Sokoll KB,Helliwell P

更新日期：2006-01-01 00:00:00