Extremely fast acceleration of cosmic rays in a supernova remnant.

abstract：:Reorganizations of the Atlantic meridional overturning circulation were associated with large and abrupt climatic changes in the North Atlantic region during the last glacial period. Projections with climate models suggest that similar reorganizations may also occur in response to anthropogenic global warming. Here I ...

journal_title：Nature

authors： Schmittner A

更新日期：2005-03-31 00:00:00

abstract：: ...

journal_title：Nature

authors： Else H

更新日期：2018-11-01 00:00:00

abstract：:The Redfield ratio of 106 carbon:16 nitrogen:1 phosphorus in marine phytoplankton is one of the foundations of ocean biogeochemistry, with applications in algal physiology, palaeoclimatology and global climate change. However, this ratio varies substantially in response to changes in algal nutrient status and taxonomi...

journal_title：Nature

authors： Sañudo-Wilhelmy SA,Tovar-Sanchez A,Fu FX,Capone DG,Carpenter EJ,Hutchins DA

更新日期：2004-12-16 00:00:00

abstract：:Butterflies rely extensively on colour vision to adapt to the natural world. Most species express a broad range of colour-sensitive Rhodopsin proteins in three types of ommatidia (unit eyes), which are distributed stochastically across the retina. The retinas of Drosophila melanogaster use just two main types, in whic...

journal_title：Nature

authors： Perry M,Kinoshita M,Saldi G,Huo L,Arikawa K,Desplan C

更新日期：2016-07-14 00:00:00

abstract：:The radiation of the mammals provides a 165-million-year test case for evolutionary theories of how species occupy and then fill ecological niches. It is widely assumed that species often diverge rapidly early in their evolution, and that this is followed by a longer, drawn-out period of slower evolutionary fine-tunin...

journal_title：Nature

authors： Venditti C,Meade A,Pagel M

更新日期：2011-10-19 00:00:00

abstract：:Overfishing of large-bodied benthic fishes and their subsequent population collapses on the Scotian Shelf of Canada's east coast and elsewhere resulted in restructuring of entire food webs now dominated by planktivorous, forage fish species and macroinvertebrates. Despite the imposition of strict management measures i...

journal_title：Nature

authors： Frank KT,Petrie B,Fisher JA,Leggett WC

更新日期：2011-07-27 00:00:00

abstract：:Vaccines against a variety of infectious diseases represent one of the great triumphs of medicine. The immune correlates of protection induced by most current vaccines seem to be mediated by long-lived humoral immune responses. By contrast, there are no currently available vaccines that are uniformly effective for dis...

journal_title：Nature

authors： Seder RA,Hill AV

更新日期：2000-08-17 00:00:00

abstract：:Mesenchymal cells contribute to the 'stroma' of most normal and malignant tissues, with specific mesenchymal cells participating in the regulatory niches of stem cells. By examining how mesenchymal osteolineage cells modulate haematopoiesis, here we show that deletion of Dicer1 specifically in mouse osteoprogenitors, ...

journal_title：Nature

authors： Raaijmakers MH,Mukherjee S,Guo S,Zhang S,Kobayashi T,Schoonmaker JA,Ebert BL,Al-Shahrour F,Hasserjian RP,Scadden EO,Aung Z,Matza M,Merkenschlager M,Lin C,Rommens JM,Scadden DT

更新日期：2010-04-08 00:00:00

abstract：:Activation of many T-cell functions depends on their interaction with antigen-presenting accessory cells which express I region associated (Ia) products. Cells expressing accessory cell function include those of the monocyte/macrophage lineage and dendritic cells. More recently, B cells and a number of tumour cell lin...

journal_title：Nature

authors： Ramila G,Erb P

更新日期：1983-08-04 00:00:00

abstract：:Population-level analyses often use average quantities to describe heterogeneous systems, particularly when variation does not arise from identifiable groups. A prominent example, central to our current understanding of epidemic spread, is the basic reproductive number, R(0), which is defined as the mean number of inf...

journal_title：Nature

authors： Lloyd-Smith JO,Schreiber SJ,Kopp PE,Getz WM

更新日期：2005-11-17 00:00:00

abstract：:Neurons in the brain behave as nonlinear oscillators, which develop rhythmic activity and interact to process information. Taking inspiration from this behaviour to realize high-density, low-power neuromorphic computing will require very large numbers of nanoscale nonlinear oscillators. A simple estimation indicates t...

journal_title：Nature

authors： Torrejon J,Riou M,Araujo FA,Tsunegi S,Khalsa G,Querlioz D,Bortolotti P,Cros V,Yakushiji K,Fukushima A,Kubota H,Yuasa S,Stiles MD,Grollier J

更新日期：2017-07-26 00:00:00

abstract：:The main asteroid belt lies between the orbits of Mars and Jupiter, but the region is not uniformly filled with asteroids. There are gaps, known as the Kirkwood gaps, in distinct locations that are associated with orbital resonances with the giant planets; asteroids placed in these locations will follow chaotic orbits...

journal_title：Nature

authors： Minton DA,Malhotra R

更新日期：2009-02-26 00:00:00

abstract：: ...

journal_title：Nature

authors： Del Bello L

更新日期：2018-12-01 00:00:00

abstract：:Abundant data link hypercholesterolaemia to atherogenesis. However, only recently have we appreciated that inflammatory mechanisms couple dyslipidaemia to atheroma formation. Leukocyte recruitment and expression of pro-inflammatory cytokines characterize early atherogenesis, and malfunction of inflammatory mediators m...

journal_title：Nature

authors： Libby P

更新日期：2002-12-19 00:00:00

abstract：:Hutchinson-Gilford progeria syndrome (HGPS) is a rare and fatal human premature ageing disease, characterized by premature arteriosclerosis and degeneration of vascular smooth muscle cells (SMCs). HGPS is caused by a single point mutation in the lamin A (LMNA) gene, resulting in the generation of progerin, a truncated...

journal_title：Nature

authors： Liu GH,Barkho BZ,Ruiz S,Diep D,Qu J,Yang SL,Panopoulos AD,Suzuki K,Kurian L,Walsh C,Thompson J,Boue S,Fung HL,Sancho-Martinez I,Zhang K,Yates J 3rd,Izpisua Belmonte JC

更新日期：2011-04-14 00:00:00

abstract：:A complex between HLA-DR3 and a fragment of invariant chain called CLIP was isolated from a human cell line defective in antigen presentation and its X-ray crystal structure determined. Previous data indicate that this complex is an intermediate in class II histocompatibility maturation, occurring between invariant ch...

journal_title：Nature

authors： Ghosh P,Amaya M,Mellins E,Wiley DC

更新日期：1995-11-30 00:00:00

abstract：:For unknown reasons, autoimmune diseases such as type 1 diabetes develop after prolonged periods of inflammation of mononuclear cells in target tissues. Here we show that progression of pancreatic islet inflammation to overt diabetes in nonobese diabetic (NOD) mice is driven by the 'avidity maturation' of a prevailing...

journal_title：Nature

authors： Amrani A,Verdaguer J,Serra P,Tafuro S,Tan R,Santamaria P

更新日期：2000-08-17 00:00:00

abstract：:Sudden, large-scale and diffuse human migration can amplify localized outbreaks of disease into widespread epidemics1-4. Rapid and accurate tracking of aggregate population flows may therefore be epidemiologically informative. Here we use 11,478,484 counts of mobile phone data from individuals leaving or transiting th...

journal_title：Nature

authors： Jia JS,Lu X,Yuan Y,Xu G,Jia J,Christakis NA

更新日期：2020-06-01 00:00:00

abstract：:Introduction of DNA fragments, hundreds of kilobases in size, into mouse embryonic stem (ES) cells would greatly advance the ability to manipulate the mouse genome. Mice generated from such modified cells would permit investigation of the function and expression of very large or crudely mapped genes. Large DNA molecul...

journal_title：Nature

authors： Jakobovits A,Moore AL,Green LL,Vergara GJ,Maynard-Currie CE,Austin HA,Klapholz S

更新日期：1993-03-18 00:00:00

abstract：:We have postulated that an excitatory postsynaptic potential (e.p.s.p.) may open voltage-sensitive K+ ('M') channels, in an appropriate depolarizing range, and that this could alter the e.p.s.p. waveform. Consequently, the fast e.p.s.p. in neurones of sympathetic ganglia, elicited by a nicotinic action of acetylcholin...

journal_title：Nature

authors： Tosaka T,Tasaka J,Miyazaki T,Libet B

更新日期：1983-09-08 00:00:00

abstract：:Transcriptional silencing of the HM mating-type loci in the yeast Saccharomyces cerevisiae is caused by the localized formation of an altered chromatin structure, analogous to heterochromatin in higher eukaryotes. Silencing depends on cis-acting sequences, termed silencers, as well as several trans-acting factors, inc...

journal_title：Nature

authors： Triolo T,Sternglanz R

更新日期：1996-05-16 00:00:00

abstract：:The axial relationship between the collagen and mineral componetns in calcified turkey leg tendon was investigated using low-angle X-ray and neutron diffraction. The results indicate that the mineral is arranged with the same axial periodicity as the collagen and occupies the gap region of the collagen structure. ...

journal_title：Nature

authors： White SW,Hulmes DJ,Miller A,Timmins PA

更新日期：1977-03-31 00:00:00

abstract：: ...

journal_title：Nature

authors： Jia H

更新日期：2018-11-01 00:00:00

abstract：:According to the generally accepted scenario, the last giant impact on Earth formed the Moon and initiated the final phase of core formation by melting Earth's mantle. A key goal of geochemistry is to date this event, but different ages have been proposed. Some argue for an early Moon-forming event, approximately 30 m...

journal_title：Nature

authors： Jacobson SA,Morbidelli A,Raymond SN,O'Brien DP,Walsh KJ,Rubie DC

更新日期：2014-04-03 00:00:00

abstract：:The spacing of opening-mode fractures in layered materials--such as certain sedimentary rocks and laminated engineering materials--is often proportional to the thickness of the fractured layer. Experimental studies of this phenomenon show that the spacing initially decreases as extensional strain increases in the dire...

journal_title：Nature

authors： Bai T,Pollard DD,Gao H

更新日期：2000-02-17 00:00:00

abstract：:Comparisons of three-dimensional maps of vertebrate muscle thin filaments obtained by cryo-electron microscopy and image analysis, reveal the molecular structure of F-actin, the location of the C terminus of the monomer and the positions of the binding sites of tropomyosin, the myosin head and the N-terminal portion o...

journal_title：Nature

authors： Milligan RA,Whittaker M,Safer D

更新日期：1990-11-15 00:00:00

abstract：:Surgical, pharmacological and genetic lesion studies have revealed distinct anatomical sites involved with different forms of learning. Studies of patients with localized brain damage and work in rodent model systems, for example, have shown that the hippocampal formation participates in acquisition of declarative tas...

journal_title：Nature

authors： Dubnau J,Grady L,Kitamoto T,Tully T

更新日期：2001-05-24 00:00:00

abstract：:Electrophoretic studies suggest that bacterial populations consist of a number of independent clones and that genetic recombination is rare in nature. But DNA sequencing reveals that individual bacterial genes have a mosaic structure that could have arisen only by recombination. How can these observations be reconcile...

journal_title：Nature

authors： Smith JM,Dowson CG,Spratt BG

更新日期：1991-01-03 00:00:00

abstract：:The hydrosulphide ion (HS(-)) and its undissociated form, hydrogen sulphide (H(2)S), which are believed to have been critical to the origin of life on Earth, remain important in physiology and cellular signalling. As a major metabolite in anaerobic bacterial growth, hydrogen sulphide is a product of both assimilatory ...

journal_title：Nature

authors： Czyzewski BK,Wang DN

更新日期：2012-03-11 00:00:00

abstract：:The neuronal structure and connectivity underlying receptive field organisation of cells in the cat visual cortex have been investigated. Intracellular recordings were made using a micropipette filled with a histochemical marker, which was injected into the cells after their receptive fields had been characterised. Th...

journal_title：Nature

authors： Gilbert CD,Wiesel TN

更新日期：1979-07-12 00:00:00