Abstract：
:Cough is an important component of airway clearance, particularly in individuals with intrinsic pulmonary disease, weakness of respiratory muscles, or central nervous system disease that impairs breathing. The use of assisted cough to enhance airway clearance in individuals with neuromuscular disease is essential to produce and maintain peak cough flow above a minimum and thereby avoid retained secretions that cause infection, inflammation, and respiratory failure. Periodic insufflation of the lung above a reduced vital capacity is also important, to maintain range of motion of the thoracic cage and avoid progressive respiratory disability. Mechanical insufflation-exsufflation is a therapy in which the device (the CoughAssist In-Exsufflator is the only currently marketed insufflation-exsufflation device) gradually inflates the lungs (insufflation), followed by an immediate and abrupt change to negative pressure, which produces a rapid exhalation (exsufflation), which simulates a cough and thus moves secretions cephalad. Mechanical insufflation-exsufflation is used with patients with neuromuscular disease and muscle weakness due to central nervous system injury. Insufflation-exsufflation decreases episodes of respiratory failure, particularly during upper-respiratory-tract infection, and provides greater success in weaning from mechanical ventilation than do conventional methods. Alternatives to insufflation-exsufflation that can produce sufficient peak cough flow for airway clearance include (1) insufflation to maximum insufflation capacity (via breath-stacking with a bag and mask, a volume ventilator, or glossopharyngeal breathing) followed by a spontaneous cough, and (2) manually assisted cough with an abdominal thrust. The effectiveness of insufflation-exsufflation in patients with obstructive lung disease, such as chronic obstructive pulmonary disease or asthma, and in pediatric patients, is less clear.
journal_name
Respir Carejournal_title
Respiratory careauthors
Homnick DNsubject
Has Abstractpub_date
2007-10-01 00:00:00pages
1296-305; discussion 1306-7issue
10eissn
0020-1324issn
1943-3654journal_volume
52pub_type
杂志文章,评审相关文献
Respiratory Care文献大全abstract：BACKGROUND:Switching patients affected by early severe ARDS and undergoing extracorporeal membrane oxygenation (ECMO) from controlled ventilation to spontaneous breathing can be either beneficial or harmful, depending on how effectively the breathing pattern is controlled with ECMO. Identifying the factors associated w...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.07391
更新日期：2020-07-01 00:00:00
abstract：:Although oral and injectable drug formulations still dominate the market, interest in pulmonary delivery has been rising steadily. Given patients' desire for an alternative to injections, and recent advances in aerosol science and pulmonary medicine, the potential for improved disease management outcomes by using aero...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：
更新日期：2000-07-01 00:00:00
abstract：:An 8-year-old female with pancreatic-insufficiency cystic fibrosis presented with recurrent pharyngitis, and reduction in body mass index and height velocity during the previous 2 years. Her symptoms (eg, snoring and restless sleep) suggested obstructive sleep apnea, and physical examination revealed tonsillar hypertr...
journal_title：Respiratory care
pub_type： 杂志文章
doi：
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:Treatment of bronchiectasis includes drugs, oxygen therapy, and bronchial-clearance maneuvers. OBJECTIVE:To assess the safety and efficacy of intrapulmonary percussive ventilation (IPV) compared to traditional standard chest physical therapy in patients with bronchiectasis and productive cough. METHODS:In ...
journal_title：Respiratory care
pub_type： 杂志文章,随机对照试验
doi：10.4187/respcare.01098
更新日期：2011-07-01 00:00:00
abstract：:Home oxygen therapy equipment options have increased over the past several decades, in response to innovations in technology, economic pressure from third-party payers, and patient demands. The delivery of oxygen in the home has evolved from packaged gas systems containing 99% United States Pharmacopeia oxygen provide...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：10.4187/respcare.01932
更新日期：2013-01-01 00:00:00
abstract：:Congenital parenchymal lung malformations have an estimated incidence at 1:25,000-1:35,000 births. We present a case of this rare congenital abnormality in a 38 year-old male, review the current literature with discussion of proposed causes, malignant potential, and management strategies. A 38-year-old white male pre...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：10.4187/respcare.00727
更新日期：2012-02-01 00:00:00
abstract：:We present a case of unilateral airflow obstruction during forced exhalations. The patient presented with episodic dyspnea and wheezing, particularly when he lay in the right lateral decubitus position. Spirometry revealed symmetric, marked reductions in forced expiratory volume in the first second and forced vital ca...
journal_title：Respiratory care
pub_type： 杂志文章
doi：
更新日期：2002-06-01 00:00:00
abstract：BACKGROUND:We tested whether work of breathing in premature newborns estimated by phase angle (θ) by using respiratory inductance plethysmography is decreased during neurally-adjusted ventilatory assist (NAVA) noninvasive ventilation (NIV) versus NIV alone. METHODS:NAVA NIV and NIV were applied in random order while u...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.07257
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:To describe the self-expanding endobronchial occluder, as utilized in bronchoscopic lung volume reduction, with a 36 month follow-up procedure. METHODS:Twenty-three subjects with severe emphysema were recruited and underwent flexible bronchoscopic placement of self-expanding endobronchial occluders. Outcomes...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.02218
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND:Some patients with obstructive sleep apnea syndrome remove the CPAP device during sleep, although they start CPAP at bedtime. We hypothesized that body position changes and oxygen desaturations may be associated with patient removal of the CPAP device. METHODS:We consecutively enrolled 36 poor CPAP adherers...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.03520
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND:Readmission of mechanically ventilated patients to an ICU within 7 d reflects not only patient safety but also the quality of care of the ICU. This study aimed to investigate the risk and related factors for readmission to an ICU within 7 d in mechanically ventilated subjects. METHODS:A total of 658,452 mec...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.03868
更新日期：2015-12-01 00:00:00
abstract：:Inhaled aerosol drugs commonly used by patients with chronic obstructive pulmonary disease include short-acting and long-acting bronchodilators, as well as corticosteroids. These agents are available in a variety of inhaler devices, which include metered-dose inhalers (MDI), breath-actuated MDIs, nebulizers, and, curr...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：
更新日期：2006-02-01 00:00:00
abstract：:Mechanical ventilation incurs substantial morbidity, mortality, and costs. Both premature extubation and delayed extubation can cause harm. Therefore, weaning that is both expeditious and safe is highly desirable. The purpose of this review is to summarize the literature related to weaning modes, spontaneous breathing...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：
更新日期：2001-12-01 00:00:00
abstract：OBJECTIVE:To investigate the predictive value of the maximal inspiratory pressure obtained by a digital vacuometer using a unidirectional valve (P(ImaxUV)) as to weaning outcome, and to compare its performance with the respiratory drive using airway occlusion pressure at 0.1 second (P(0.1)), and P(0.1)/P(ImaxUV). METH...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.01489
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND:This study compared 3 nebulizer technologies for inter- and intradevice reproducibility, humidification, and fill volume sensitivity during mechanical ventilation: a breath-enhanced jet nebulizer, a vibrating mesh nebulizer, and a jet nebulizer. The breath-enhanced jet nebulizer featured a new design located...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.07639
更新日期：2020-10-01 00:00:00
abstract：:Health care costs continue to skyrocket, and a large portion of these costs can be attributed to technology. Some technology, such as oximetry, is relatively inexpensive compared to CAT scanning and magnetic resonance imaging. Therefore, it may elude close scrutiny and direct health care planning and, with little fanf...
journal_title：Respiratory care
pub_type： 杂志文章
doi：
更新日期：1988-04-01 00:00:00
abstract：BACKGROUND:The present study aimed to characterize the behavior of 3 components of respiratory muscle function during mechanical ventilation weaning in children to better understand the respective impact of a spontaneous breathing trial on ventilatory mechanical action (esophageal pressure [Pes], ventilatory demand (el...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.06351
更新日期：2019-05-01 00:00:00
abstract：:Oxygen is a colorless, odorless, tasteless gas that is utilized by the body for respiration. Oxygen has played a major role in respiratory care. Oxygen therapy is useful in treating hypoxemia but is often thought of as a benign therapy. After many years of study, we have learned a great deal of the benefits and potent...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：10.4187/respcare.05245
更新日期：2017-06-01 00:00:00
abstract：:Dexmedetomidine is a selective alpha-2 receptor agonist that possesses both sedative and analgesic properties, with minimal respiratory depression. We report the successful administration of dexmedetomidine on a 16-year-old primigravida woman that allowed the patient to tolerate application of bi-level positive airwa...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.01733
更新日期：2012-11-01 00:00:00
abstract：:Mass-care events, such as pandemic influenza, could reach such devastating proportions that there will be the need to make difficult triage decisions that will ultimately result in the deaths or severe disability of patients in large numbers. The method by which we determine how triage of scarce health care resources ...
journal_title：Respiratory care
pub_type： 杂志文章
doi：
更新日期：2008-02-01 00:00:00
abstract：:Sleep-disordered breathing (mainly obstructive sleep apnea [OSA]) and COPD are among the most common pulmonary diseases, so a great number of patients have both disorders; this "overlap syndrome" causes more severe nocturnal hypoxemia than either disease alone. This common combination of OSA and COPD has important imp...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:Field walking tests are commonly used in patients with chronic pulmonary diseases for assessment of functional capacity. However, the physiological demands and magnitude of desaturation on 6-min walk test (6MWT), incremental shuttle walk test (ISWT), and endurance shuttle walk test (ESWT) have not been inves...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.07171
更新日期：2020-05-01 00:00:00
abstract：:Initial management of patients with difficult-to-treat asthma must begin with confirmation of the diagnosis. We present 2 cases of tracheal disease misdiagnosed as difficult-to-treat asthma. After systemic evaluation, tracheomalacia and tracheobronchial narrowing due to diffuse calcification of the cartilaginous rings...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.02350
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:The diagnosis of tuberculous pleural effusion (TBPE) has some limitations. We studied the efficacy of interleukin-27 (IL-27) in the diagnosis of TBPE. METHODS:We measured IL-27, adenosine deaminase (ADA), ADA-2, interferon-gamma (IFNγ), and the ADA·IL-27 and ADA-2·IL-27 products in all the pleural effusion ...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.02749
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:The impulse oscillometry system (IOS) is increasingly used to evaluate lung function, but individual results must be compared with appropriate reference values. We aimed to obtain such reference values in Mexican children and adolescents. METHODS:Healthy subjects were recruited from kindergartens and school...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.03374
更新日期：2015-01-01 00:00:00
abstract：:Patients who require mechanical ventilation in the prehospital and emergency department environments experience high mortality and are at high risk of ventilator-associated ventilator-induced lung injury and ARDS. In addition, little attention has been given in the literature, trainee education, or clinical emphasis t...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：10.4187/respcare.06888
更新日期：2019-05-01 00:00:00
abstract：:Aerosolized medications are routinely used for the treatment of critically ill patients. This paper reviews aerosol delivery devices with a focus on issues related to their performance in pulmonary critical care. Factors affecting aerosol drug delivery to mechanically ventilated adults and spontaneously breathing pati...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：10.4187/respcare.03790
更新日期：2015-06-01 00:00:00
abstract：:The story of the development of oxygen and its role in mitigating the ravages of chronic stable hypoxemia have been fascinating. Today, over one million Americans receive home oxygen each day, usually for COPD, from one of the three available systems. The future requires less expensive, highly portable, and practical ...
journal_title：Respiratory care
pub_type： 历史文章,杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND:Healthy individuals without respiratory symptoms can sometimes present with low FEV1/FVC. The objective of this study was to characterize and compare subjects without symptoms and with reduced FEV1/FVC but normal FEV1 with subjects with mild obstructive lung disease. METHODS:Fifty healthy subjects with FEV1...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.06131
更新日期：2019-05-01 00:00:00
abstract：BACKGROUND:High-flow nasal cannula (HFNC) is commonly being used to provide noninvasive respiratory support in newborn infants. Continuous distending pressure generated by these devices in preterm infants has not been elucidated. The aim of this work was to determine the association between HFNC flow in L/min and end-e...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.04317
更新日期：2016-03-01 00:00:00
