Babesia gibsoni: identification of an immunodominant, interspersed repeat antigen.

abstract：:We investigated dried red leaf extracts of Sorghum bicolor for activity against Toxoplasma gondii tachyzoites. S. bicolor red leaf extracts were obtained by bioassay-guided fractionation using ethanol and ethyl acetate as solvents. Analysis of the crude and fractionated extracts from S. bicolor using electrospray ioni...

journal_title：Experimental parasitology

authors： Abugri DA,Witola WH,Jaynes JM,Toufic N

更新日期：2016-05-01 00:00:00

abstract：:Rosetting is a parasite adhesion phenotype associated with severe malaria in African children. Why parasites form rosettes is unknown, although enhanced invasion or immune evasion have been suggested as possible functions. Previous work showed that rosetting does not enhance parasite invasion under standard in vitro c...

journal_title：Experimental parasitology

authors： Deans AM,Rowe JA

更新日期：2006-04-01 00:00:00

abstract：:Phlebotomus papatasi is susceptible to Leishmania major which it transmits in nature, but is resistant to L. donovani. The present study compares the effect of L. major and L. donovani on the proteolytic activity of P. papatasi gut enzymes. The experiments measured digestion of C14-labeled globin by gut homogenates of...

journal_title：Experimental parasitology

authors： Schlein Y,Romano H

更新日期：1986-12-01 00:00:00

abstract：:Differences in gene expression between adult and immature Fasciola hepatica (liver fluke) parasites isolated from the mammalian host were investigated using the technique of differential display. For any given primer combination used to produce these displays there were, on average, 22% apparently adult-specific and 1...

journal_title：Experimental parasitology

authors： Reed MB,Spithill TW,Strugnell RA,Panaccio M

更新日期：1998-06-01 00:00:00

abstract：:The kinetics of specific immunoglobulin M, A and IgG subclasses against Echinostoma caproni (Trematoda: Echinostomatidae) were analyzed in serum and intestinal fluid of two host species (Wistar rats and ICR mice) in which the course of the infection markedly differs. In rats, the worms were rapidly expelled, whereas E...

journal_title：Experimental parasitology

authors： Sotillo J,Muñoz-Antoli C,Marcilla A,Fried B,Guillermo Esteban J,Toledo R

更新日期：2007-08-01 00:00:00

abstract：:Canine leishmaniosis due to Leishmania infantum is a widespread zoonotic disease. Although aminosidine can be an effective treatment, current therapeutic recommendations do not advocate its use, mainly due to concerns regarding the potential nephrotoxicity and ototoxicity of this drug. The aim of this randomized, blin...

journal_title：Experimental parasitology

authors： Kasabalis D,Chatzis MK,Apostolidis K,Xenoulis PG,Buono A,Petanides T,Leontides LS,Polizopoulou ZS,Steiner JM,Suchodolski JS,Saridomichelakis MN

更新日期：2019-11-01 00:00:00

abstract：:In order to examine the role of IFN-gamma, TNFRp55 and iNOS in inflammatory reaction during toxoplasmosis, IFN-gamma(-/-), TNFRp55(-/-) and iNOS(-/-) mice were experimentally infected with Toxoplasma gondii ME-49 strain. The organs of the mice were evaluated for histology and immunohistochemistry in detection of tissu...

journal_title：Experimental parasitology

authors： Silva NM,Vieira JC,Carneiro CM,Tafuri WL

更新日期：2009-09-01 00:00:00

abstract：:Root lesion nematodes (RLNs, Pratylenchus species) are a group of economically important migratory endoparasitic plant pathogens that attack host roots of major crops such as wheat and sugarcane, and can reduce crop yields by 7-15%. Pratylenchus thornei and Pratylenchus zeae were treated with double stranded RNA (dsRN...

journal_title：Experimental parasitology

authors： Tan JA,Jones MG,Fosu-Nyarko J

更新日期：2013-02-01 00:00:00

abstract：:Rhipicephalus microplus, the cattle tick, is a major cause of economic losses in bovine production. Due to the widespread acaricidal resistance to commercially available products, as well as their toxicity and environmental impact, alternative control methods are required. Nanoformulations produced from plant extracts...

journal_title：Experimental parasitology

authors： Nogueira JAP,Figueiredo A,Duarte JL,de Almeida FB,Santos MG,Nascimento LM,Fernandes CP,Mourão SC,Toscano JHB,Rocha LM,Chagas ACS

更新日期：2020-08-01 00:00:00

abstract：:Acanthamoeba spp., known to cause keratitis and granulomatous encephalitis in humans, are frequently isolated from a variety of water sources. Here we report for the first time the characterization of an Acanthamoeba sp. (ACC01) isolated from tap water in Brazil. This organism is currently being maintained in an axeni...

journal_title：Experimental parasitology

authors： Magliano AC,da Silva FM,Teixeira MM,Alfieri SC

更新日期：2009-11-01 00:00:00

abstract：:Microtus fortis is a non-permissive host for Schistosoma japonicum. While M. fortis lymphocytes are known to provide natural resistance against S. japonicum, the specific mechanism remains unclear. A bone marrow transplantation (BMT) model was established using immunodeficient mice, either nude (experiment 1) or V(D)J...

journal_title：Experimental parasitology

authors： Hu Y,Xu Y,Lu W,Quan H,Shen Y,Yuan Z,Zhang J,Zang W,He Y,Cao J

更新日期：2014-07-01 00:00:00

abstract：:A polymerase chain reaction (PCR-based) assay was evaluated for detection of Trypanosoma evansi DNA in experimentally infected mice and naturally infected camels, sheep and goats using the set of primers TBr(1) & TBr(2) that amplified 164 bp DNA fragment. The results revealed that PCR-based assay was able to detect T....

journal_title：Experimental parasitology

authors： Ashour AA,Abou El-Naga TR,Barghash SM,Salama MS

更新日期：2013-05-01 00:00:00

abstract：:In the intestinal tract of fifth instars of the hematophagous reduviid bugs Rhodnius prolixus and Triatoma infestans blood ingestion induced an initial decrease of the concentration of the respective symbiotic bacteria Rhodococcus rhodnii and Nocardia sp. and then within 10 days a 15- or 18-fold increase of the total ...

journal_title：Experimental parasitology

authors： Eichler S,Schaub GA

更新日期：2002-01-01 00:00:00

abstract：:Giardia lamblia undergo surface antigenic variation in vitro and in vivo. The presence of variant trophozoites can be detected in clones after exposure to cytotoxic monoclonal antibodies. Surviving Giardia (progeny) no longer possess the initial major surface antigen which is replaced by new antigens. Exposure of a cl...

journal_title：Experimental parasitology

authors： Nash TE

更新日期：1989-02-01 00:00:00

abstract：:Nitric oxide (NO), derived from catalysis of inducible NO synthase (iNOS), limits malaria parasite growth in mammals. Transforming growth factor (TGF)-beta1 suppresses iNOS in cells in vitro as well as in vivo in mice, but paradoxically severe malaria in humans is associated with low levels of TGF-beta1. We hypothesiz...

journal_title：Experimental parasitology

authors： Luckhart S,Lieber MJ,Singh N,Zamora R,Vodovotz Y

更新日期：2008-02-01 00:00:00

abstract：PURPOSE:Praziquantel (PZQ) is the conventional antibilharzial agent. Nevertheless, no antibilharzial prophylactic agents or 100% curable therapy approved and no reported data about use of human CD34+ Umbilical Cord Blood Stem Cells (CD34+UCBSCs) or Wharton Jelly Mesenchymal Stem Cells (WJMSCs) in prevention and/or comp...

journal_title：Experimental parasitology

authors： Magdy M,Fahmy A,Zaki NI,Mohamed AK

更新日期：2020-10-01 00:00:00

abstract：:Three-day-old specific-pathogen-free chickens were subcutaneously immunized with Eimeria tenella recombinant 5401 antigen (100 microg per chicken) with (0.25, 0.5 or 1.0mg per dose) or without ginsenosides, and boosted with the same dosage 14 days later. The chickens were challenged with 6 x 10(4) homologous sporulate...

journal_title：Experimental parasitology

authors： Du A,Hu S,Wang S

更新日期：2005-11-01 00:00:00

abstract：:Axenic culture of Leishmania is generally performed in rich, serum-supplemented media which sustain robust growth over multiple passages. The use of such undefined media, however, obscures proteomic analyses and confounds the study of metabolism. We have established a simple, defined culture medium that supports the s...

journal_title：Experimental parasitology

authors： Nayak A,Akpunarlieva S,Barrett M,Burchmore R

更新日期：2018-02-01 00:00:00

abstract：:Toxoplasmosis is a widely distributed disease caused by the protozoan Toxoplasma gondii that is mainly transmitted orally. Once ingested, the parasite crosses the intestinal barrier to reach the blood and lymph systems to migrate to other regions of the host. The objective of this study was to evaluate the changes in ...

journal_title：Experimental parasitology

authors： Vicentino-Vieira SL,Nogueira de Melo Gde A,Biondaro Góis M,Martins Moreira N,de Araujo Pereira LG,de Almeida Araújo EJ,Garcia JL,de Mello Gonçales Sant'Ana D

更新日期：2015-09-01 00:00:00

abstract：:This paper describes the in vitro multiplication process of Babesia bigemina sporokinetes in a cell line (IDE8) from Ixodes scapularis ticks. The inoculum was obtained from hemolymph of engorged females of Rhipicephalus (Boophilus) microplus ticks naturally infected with B. bigemina. These ticks had been fed on calves...

journal_title：Experimental parasitology

authors： Ribeiro MF,Bastos CV,Vasconcelos MM,Passos LM

更新日期：2009-07-01 00:00:00

abstract：:Monoclonal antibodies (mAb) directed against Schistosoma mansoni tropomyosin isoform, SMTM (Xu et al. Experimental Parasitology 69, 373-392, 1989), were used to test for cross-reactivity with Biomphalaria glabrata antigens. One mAb (1F10) recognized antigens of 39, 41, and 80 kDa in a snail head/foot antigen preparati...

journal_title：Experimental parasitology

authors： Weston D,Allen B,Thakur A,LoVerde PT,Kemp WM

更新日期：1994-05-01 00:00:00

abstract：:EhRabB is an Entamoeba histolytica protein involved in phagocytosis. However, proteins that regulate the EhRabB activity are unknown. Here, we report the identification of a putative G protein-coupled receptor of E. histolytica (EhGPCR-1) that binds to EhRabB. By two-hybrid screening, we found a 372-bp cDNA fragment t...

journal_title：Experimental parasitology

authors： Picazarri K,Luna-Arias JP,Carrillo E,Orozco E,Rodriguez MA

更新日期：2005-07-01 00:00:00

abstract：:The excretory/secretory (ES) proteins of schistosomes play important roles in modulating host immune systems and are regarded as potential vaccine candidates and drug targets. Protein disulfide isomerase (PDI) is an essential enzyme that is involved in disulfide bond formation and rearrangement. In the present study, ...

journal_title：Experimental parasitology

authors： Cao X,Hong Y,Zhang M,Han Y,Wu M,Wang X,Guo X,Li C,Lu K,Li H,Fu Z,Lin J

更新日期：2014-11-01 00:00:00

abstract：:Resistance and sensitivity to normal human serum (NHS) of Trypanosoma congolense, a parasite believed to cause disease in animals only, were investigated in vivo as well as in vitro. Our results indicate that like Trypanosoma brucei, T. congolense can be grouped into three different phenotypes according to its resista...

journal_title：Experimental parasitology

authors： Xong HV,De Baetselier P,Pays E,Magez S

更新日期：2002-10-01 00:00:00

abstract：:Members of a serologically cross-reacting family of proteins including Ag332 and Pf11.1, megadalton proteins of schizont-infected red blood cells, and gametocytes, respectively, and Pf155-RESA, a 155-kDa protein of ring-infected red blood cells, have been reported to share amino acid repeat sequences. These repeats ar...

journal_title：Experimental parasitology

authors： Barnes DA,Wollish W,Nelson RG,Leech JH,Petersen C

更新日期：1995-08-01 00:00:00

abstract：:In murine Schistosoma mansoni infections, fewer adult worms develop in male than in female mice infected with the same number of cercariae. To evaluate a potential role for testosterone in this phenomenon, testosterone levels were manipulated in groups of CBA/J mice that were then infected and monitored for survival r...

journal_title：Experimental parasitology

authors： Nakazawa M,Fantappie MR,Freeman GL Jr,Eloi-Santos S,Olsen NJ,Kovacs WJ,Secor WE,Colley DG

更新日期：1997-03-01 00:00:00

abstract：:Chryseobacterium indologenes and Chryseobacterium gleum are Gram negative environmental bacteria that have been frequently reported to implicate in fatal nosocomial infections, such as bacteraemia and ventilator-associated pneumonia in immunocompromised individuals in the past decades. The interaction between Chryseob...

journal_title：Experimental parasitology

authors： Lim WG,Tong T,Chew J

更新日期：2020-02-19 00:00:00

abstract：:Transforming growth factor-β (TGF-β) signaling pathway is documented to participate in liver fibrosis via multifactorial mechanisms. microRNA Let-7b (Let-7b) has been proved to alleviate cell fibrosis through regulating TGF-β receptor I (TβRI), but whether it is involved in Schistosomiasis liver fibrosis (SLF) has not...

journal_title：Experimental parasitology

authors： Tang N,Wu Y,Cao W,Liang Y,Gao Y,Hu L,Yang Q,Zhou Y,Tang F,Xiao J

更新日期：2017-11-01 00:00:00

abstract：:Basic aspects of the generation, structure and function of Echinococcus granulosus protoscoleces are unknown. We review the work done on the structure and ultrastructure of the E. granulosus protoscolex and provide new data together with a comprehensive view of this form of the parasite. The surface, as observed by sc...

journal_title：Experimental parasitology

authors： Galindo M,Schadebrodt G,Galanti N

更新日期：2008-08-01 00:00:00

abstract：:Trypanosoma cruzi infection in humans and experimental animals often results in a chronic heart and gut inflammation and a dysfunction known as Chagas' disease. Previous studies have shown that the cellular infiltrate in the hearts of animals with chronic Chagas' disease consists mainly of CD8+ T cells. In this study,...

journal_title：Experimental parasitology

authors： Zhang L,Tarleton RL

更新日期：1996-11-01 00:00:00