Abstract:
:Action control deficits of schizophrenia patients result from frontostriatal brain abnormalities and presumably reflect an impairment of selective cognitive processes. This study aimed at dissociating two different levels of action control in saccades toward and away from visual stimuli (pro- and antisaccades). Results of previous studies suggested that task switch effects (between pro- and antisaccades) reflect the persistence of a task-specific production rule and refer to the level of task selection, whereas response switch effects (between leftward and rightward saccades) point to the persistence of a specific response program, referring to the level of response selection. In the present study, task switching and response switching were investigated in 20 schizophrenia patients and 20 control subjects. Groups did not differ concerning task switch effects. In contrast, response switching entailed a stronger enhancement of error rates in patients, suggesting a specific deficit on the level of response selection in schizophrenia. The deficit was associated with spatial working memory capacities, confirming and specifying existing hypotheses on a relationship between working memory and action control.
journal_name
Biol Psycholjournal_title
Biological psychologyauthors
Franke C,Reuter B,Schulz L,Kathmann Ndoi
10.1016/j.biopsycho.2007.06.006subject
Has Abstractpub_date
2007-09-01 00:00:00pages
91-9issue
1-2eissn
0301-0511issn
1873-6246pii
S0301-0511(07)00111-1journal_volume
76pub_type
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