Abstract:
BACKGROUND:In Tourette syndrome (TS) as a neurodevelopmental disorder not only the tics but also the comorbid conditions change with increasing age. ADHD is highly comorbid with TS and usually impairs psychosocial functioning more than the tics. Its impact on further comorbidity during development is important for clinical practice and still a matter of debate. METHOD:Aspects of developmental psychopathology considering the impact of ADHD were examined by logistic regression (year wisely) in a cross-sectional sample of children and adolescents (n = 5060) from the TIC database. RESULTS:In TS+ADHD (compared to TS-ADHD) higher rates of comorbid conditions like OCD, anxiety disorders, CD/ODD and mood disorders were found in children (5-10 years). In adolescents (11-17 years) higher comorbidity rates in TS+ADHD remained only for CD/ODD and mood disorders. Accordingly, for OCD and anxiety disorders there was a steeper year wise increase of these comorbidities in TS-ADHD while it was a similar for CD/ODD and mood disorders in TS-ADHD as well as TS+ADHD. CONCLUSION:Children with TS+ADHD have more comorbidities than the TS-ADHD group, whereas in both adolescent groups this did no longer hold for OCD and anxiety disorders. These findings indicate that in TS comorbid ADHD is associated with high rates of externalizing and internalizing problems, whereas TS without ADHD is associated only with internalizing problems in adolescence.
journal_name
Eur Child Adolesc Psychiatryjournal_title
European child & adolescent psychiatryauthors
Roessner V,Becker A,Banaschewski T,Freeman RD,Rothenberger A,Tourette Syndrome International Database Consortium.doi
10.1007/s00787-007-1004-6subject
Has Abstractpub_date
2007-06-01 00:00:00pages
24-35eissn
1018-8827issn
1435-165Xjournal_volume
16 Suppl 1pub_type
杂志文章abstract::Few studies have examined the effectiveness of outpatient cognitive-behavioral therapy (CBT) delivered in routine care settings for children and adolescents with mental disorders. This observational study examined changes in behavioral and emotional problems of adolescents with mental disorders during routine outpatie...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-017-1021-z
更新日期:2018-01-01 00:00:00
abstract::Children with social anxiety disorder (SAD) have been reported to display reduced social skills. Less attention has been paid to whether neurodevelopmental deficits/delays (NDD's) in language and motor function may contribute to their impaired social skills. The present study aimed to assess the extent of language and...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-007-0642-z
更新日期:2008-03-01 00:00:00
abstract::Given the known behavior effects of oxytocin,and in particular its putative effect on trust, affiliation and anxiety, we hypothesized that oxytocin may be involved in the development and expression of callous-unemotional traits in children with aggressive antisocial behavior. We recruited 162 children between the ages...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-012-0240-6
更新日期:2012-03-01 00:00:00
abstract::Child and adolescent inpatient treatment has faced major changes since the year 2000, including shorter inpatient stays and a greater use of psychotropic drugs. This study explored changes and correlates of suicidal threats and suicide acts among inpatients, by comparing Finnish cross-sectional surveys from 2000 to 20...
journal_title:European child & adolescent psychiatry
pub_type: 历史文章,杂志文章
doi:10.1007/s00787-019-01286-9
更新日期:2019-09-01 00:00:00
abstract::Despite being home to a large population of vulnerable children there is a dearth of population-based evidence on childhood mental disorders in sub-Saharan Africa. Parent and child mental health are rarely measured concurrently, despite potential for confounding with other risk factors, including parental HIV. Using t...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-018-1146-8
更新日期:2018-12-01 00:00:00
abstract::This project describes the dissemination of an evidence-based parenting skills intervention by training social and health workers with little or no mental health background so that they themselves train mothers of children with behavioral problems in impoverished communities in a developing country. The Strengths and ...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-010-0099-3
更新日期:2010-08-01 00:00:00
abstract::Although major guidelines in the field and current diagnostic criteria clearly demand an assessment of children's attention deficit/hyperactivity disorder (ADHD) symptoms at school, few studies address the fundamental question of which is the best approach for clinicians to get this information from teachers. Three sc...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-013-0466-y
更新日期:2014-06-01 00:00:00
abstract::A substantial proportion of adolescents with attention deficit hyperactivity disorder (ADHD) do not appropriately adhere to prescribed treatments, especially to pharmacological treatments. It is important to disentangle the specific attitudes that contribute to treatment adherence. A 33-item questionnaire was applied ...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-012-0277-6
更新日期:2012-07-01 00:00:00
abstract::This study aims at determining serum levels of tryptophan and other metabolites of the kynurenine pathway in children with attention deficit hyperactivity disorder (ADHD) compared to healthy controls. Such metabolites interact with glutamate receptors in the central nervous system, potentially modulating mechanisms th...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-017-1002-2
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to investigate capacity, demographic composition, and patterns of practice of Dutch child and adolescent psychiatrists, and to compare these findings with the results of a similar investigation in 1996. METHOD:A postal survey was sent out to all Dutch child and adolescent psychiatris...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-005-0480-9
更新日期:2005-09-01 00:00:00
abstract::Within the last decade, social anxiety disorder (SAD) has been identified as a highly prevalent and burdensome disorder. Both the characterization of its symptomatology and effective treatment options are widely documented. Studies particularly indicate that SAD aggregates in families and has its onset in early adoles...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章,评审
doi:10.1007/s00787-010-0138-0
更新日期:2010-12-01 00:00:00
abstract::Previous studies have suggested environmental factors may contribute to the risk of attention-deficit/hyperactivity disorder (ADHD). The current meta-analysis examined (1) the difference in the duration of maternal breastfeeding between children with and without ADHD, and (2) the association between maternal breastfee...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章,meta分析
doi:10.1007/s00787-018-1182-4
更新日期:2019-01-01 00:00:00
abstract::Attention-deficit/hyperactivity disorder (ADHD), one of the most common neuropsychiatric conditions of childhood, often has a chronic course and persists into adulthood in many individuals. ADHD may have a clinically important impact on health-related quality of life in children, a significant impact on parents' emoti...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章,评审
doi:10.1007/s00787-009-0056-1
更新日期:2010-04-01 00:00:00
abstract::Parent-mediated intervention is widely used for pre-schoolers with autism spectrum disorder (ASD). Previous studies indicate small-to-moderate effects on social communication skills, but with a wide heterogeneity that requires further research. In this randomized controlled trial (RCT), cooperative parent-mediated the...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00787-019-01395-5
更新日期:2020-07-01 00:00:00
abstract::One third of children with autistic spectrum disorders (or pervasive developmental disorders) enter that state by regression from a more normal prior development at the onset of epilepsy or epileptiform abnormality in the electroencephalogram. In a very small proportion structural lesions of the temporal lobes are dis...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s007870050128
更新日期:1999-09-01 00:00:00
abstract::Gender and sexually diverse adolescents have been reported to be at an elevated risk for suicidal thoughts and behaviors. For transgender adolescents, there has been variation in source of ascertainment and how suicidality was measured, including the time-frame (e.g., past 6 months, lifetime). In studies of clinic-ref...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-020-01663-9
更新日期:2020-11-09 00:00:00
abstract:INTRODUCTION:Difficulties imitating gestures have been found in several studies in children and adolescents with Autism Spectrum Disorders (ASD). It has been hypothesized that imitation abilities might be precursors of language abilities in young children with autism. No study on imitation and language abilities in ado...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-006-0533-8
更新日期:2006-08-01 00:00:00
abstract::Despite ample evidence linking particular child temperament characteristics to behavior disorders later in life, there is currently a lack of temperament measures that can be used early, easily, and widely for screening purposes. To redress this gap, the current research aimed at developing a very brief scale of child...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-019-01379-5
更新日期:2020-05-01 00:00:00
abstract::Animal findings of long-term effects of maternal behaviors mediated via altered GR gene expression will, if translated into humans, have far reaching implications for our understanding of child and adolescent psychopathology. We have previously shown that mothers' self-reported stroking of their infants modifies assoc...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-016-0886-6
更新日期:2017-03-01 00:00:00
abstract::Psychosocial problems during adolescence are heterogenic, rather common, and unstable. At the same time, they are associated with an elevated risk of developing psychiatric disorders later in life. We aimed to describe the trajectories of psychosocial problems during adolescence and examine potential markers of persis...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-019-01321-9
更新日期:2019-12-01 00:00:00
abstract::Formal thought disorder (FTD) is a disruption in the flow of thought, which is inferred from disorganisation of spoken language. FTD in autism spectrum disorders (ASD) might be a precursor of psychotic disorders or a manifestation of ASD symptom severity. The current longitudinal study is a seven-year follow-up of 91 ...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-014-0552-9
更新日期:2015-02-01 00:00:00
abstract::The family environment in childhood has a strong effect on mental health outcomes throughout life. This effect is thought to depend at least in part on modifications of neurodevelopment trajectories. In this exploratory study, we sought to investigate whether a feasible resting-state fMRI metric of local spontaneous o...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-018-1240-y
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Children with conduct disorders and their families come into contact with a range of community and specialist agencies. METHODS:The aim of this study was to establish the lifetime service utilisation rates among children with conduct disorders from the Great Britain National Study (N = 10,438), and to exami...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-003-0330-6
更新日期:2003-10-01 00:00:00
abstract::Half of mental disorders have their first onset before adulthood when the presence of a disorder may be particularly disruptive to developmental milestones. Retrospective prevalence estimates have been shown to underestimate the burden of mental illness and scarce data are available on the incidence of disorders throu...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-015-0721-5
更新日期:2016-02-01 00:00:00
abstract::Seven children and young adults with definite signs of Asperger syndrome were administered a battery of tests designed to test: intelligence; left and right cerebral hemisphere functioning; ability to discriminate eye gaze; and social judgment. The subjects revealed a non significant tendency to have a higher verbal I...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/BF01978114
更新日期:1994-10-01 00:00:00
abstract::Socioeconomic disadvantage has been linked to mental health difficulties in children and adolescents, although many children appear to do well despite exposure to financial adversity in childhood. Our study looked at the effects of family financial difficulty on children's mental health outcomes (n = 636) at 4-5 years...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章,多中心研究
doi:10.1007/s00787-019-01348-y
更新日期:2020-04-01 00:00:00
abstract::Psychiatric comorbidity in traumatized youth is prevalent, but such associations between two disorders may be confounded with other comorbid conditions. Few studies have examined the unique relationships among multiple disorders. Which disorders maximally explain the relationships between others and whether such disor...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-019-01400-x
更新日期:2020-06-01 00:00:00
abstract::Anorexia nervosa (AN) and bulimia nervosa (BN) are complex disorders characterized by disordered eating behavior where the patient's attitude towards weight and shape, as well as their perception of body shape, are disturbed. Formal genetic studies on twins and families suggested a substantial genetic influence for AN...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章,评审
doi:10.1007/s00787-009-0085-9
更新日期:2010-03-01 00:00:00
abstract::Previous research on autonomic characteristics of social anxiety in children and adolescents has produced highly inconsistent results which may partially be due to task differences and a limited breadth of autonomic measurement. Here we investigated a sample of high (HSA) and low socially anxious (LSA) children, aged ...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-013-0405-y
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:The impact of attention deficit hyperactive disorder (ADHD) in the Netherlands on health care utilisation, costs and quality of life of these children, as well as of their parents is unknown. OBJECTIVE:The aim of this study was to assess the direct medical costs of patients suffering from ADHD and their qua...
journal_title:European child & adolescent psychiatry
pub_type: 杂志文章
doi:10.1007/s00787-007-0603-6
更新日期:2007-08-01 00:00:00