Abstract:
:Materials, including bone, often fail due to loading in the presence of critical flaws. The relative amount, location, and interaction of these flaws within a stressed volume of material play a role in determining the failure properties of the structure. As materials are generally imperfect, larger volumes of material have higher probabilities of containing a flaw of critical size than do smaller volumes. Thus, larger volumes tend to fail at fewer cycles compared with smaller volumes when fatigue loaded to similar stress levels. A material is said to exhibit a volume effect if its failure properties are dependent on the specimen volume. Volume effects are well documented in brittle ceramics and composites and have been proposed for bone. We hypothesized that (1) smaller volumes of cortical bone have longer fatigue lives than similarly loaded larger volumes and (2) that compared with microstructural features, specimen volume was able to explain comparable amounts of variability in fatigue life. In this investigation, waisted rectangular specimens (n=18) with nominal cross-sections of 3x4 mm and gage lengths of 10.5, 21, or 42 mm, were isolated from the mid-diaphysis of the dorsal region of equine third metacarpal bones. These specimens were subjected to uniaxial load controlled fatigue tests, with an initial strain range of 4000 microstrain. The group having the smallest volume exhibited a trend of greater log fatigue life than the larger volume groups. Each volume group exhibited a significant positive correlation between the logarithm of fatigue life and the cumulative failure probability, indicating that the data follow the two-parameter Weibull distribution. Additionally, log fatigue life was negatively correlated with log volume, supporting the hypothesis that smaller stressed volumes of cortical bone possess longer fatigue lives than similarly tested larger stressed volumes.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Bigley RF,Gibeling JC,Stover SM,Hazelwood SJ,Fyhrie DP,Martin RBdoi
10.1016/j.jbiomech.2007.05.025subject
Has Abstractpub_date
2007-01-01 00:00:00pages
3548-54issue
16eissn
0021-9290issn
1873-2380pii
S0021-9290(07)00259-Xjournal_volume
40pub_type
杂志文章abstract::Here we extend the global, closed-loop, mathematical model for the cardiovascular system in Müller and Toro (2014) to account for fundamental mechanisms affecting cerebral venous haemodynamics: the interaction between intracranial pressure and cerebral vasculature and the Starling-resistor like behaviour of intracrani...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2014.08.005
更新日期:2014-10-17 00:00:00
abstract::Osteocytes actively regulate bone modeling and remodeling, direct skeletal mineralization, and regulate calcium/phosphate homeostasis and extracellular matrix metabolism; yet the specific role of osteocytes in maintaining bone structural integrity and strength is unknown. Studies have shown that the density of osteocy...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2008.01.017
更新日期:2008-01-01 00:00:00
abstract::Muscle compression commonly occurs in daily life (for instance wearing backpacks or compression garments, and during sitting). However, the effects of the compression on contraction dynamics in humans are not well examined. The aim of the study was to quantify the alterations of contraction dynamics and muscle archite...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2019.01.011
更新日期:2019-03-06 00:00:00
abstract::The longitudinal growth of long bones occurs in growth plates where chondrocytes synthesize cartilage that is subsequently ossified. Altered growth and subsequent deformity resulting from abnormal mechanical loading is often referred to as mechanical modulation of bone growth. This phenomenon has key implications in t...
journal_title:Journal of biomechanics
pub_type: 杂志文章,评审
doi:10.1016/j.jbiomech.2009.05.021
更新日期:2009-08-25 00:00:00
abstract::Although flow-diverting devices are promising treatment options for intracranial aneurysms, jailed side branches might occlude leading to insufficient blood supply. Especially differences in the local stent strut compression may have a drastic influence on subsequent endothelialization. To investigate the outcome of d...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2015.10.047
更新日期:2016-01-04 00:00:00
abstract::In this study, two different strategies of rising from a chair were compared, using integrated biomechanical and electromyographic analyses. Nine healthy subjects were instructed to rise using two different strategies: natural sit-to-stand transfer (NSTS) and a sit-to-stand transfer with full flexion of the trunk (FST...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(94)90039-6
更新日期:1994-11-01 00:00:00
abstract::When running, energy is lost during stance to redirect the center of mass of the body (COM) from downwards to upwards. The present study uses a collision-based approach to analyze how these energy losses change with slope and speed. Therefore, we evaluate separately the average collision angle, i.e. the angle of devia...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2018.12.024
更新日期:2019-01-23 00:00:00
abstract::A model is developed in which osteoblasts can sense the strains applied to a small region of bone through electrical coupling between adjacent cells. The stress-generated potentials within bone are assumed to occur through streaming potentials, and the coupled network of osteocytes is assumed to act in a manner simila...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(93)90048-j
更新日期:1993-02-01 00:00:00
abstract::Computational simulations of tissue differentiation have been able to capture the main aspects of tissue formation/regeneration observed in animal experiments-except for the considerable degree of variability reported. Understanding and modelling the source of this variability is crucial if computational tools are to ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2011.02.003
更新日期:2011-04-07 00:00:00
abstract::Stress analysis in the individual parts of the scapula under normal physiological conditions is necessary to understand the load transfer mechanism, its relation with morphology of bone and to analyse the deviations in stress patterns due to implantation of the glenoid. The purpose of this study was to obtain stress d...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2003.11.025
更新日期:2004-07-01 00:00:00
abstract::The successful development of early-stage cartilage and meniscus repair interventions in the knee requires biomechanical and biotribological understanding of the design of the therapeutic interventions and their tribological function in the natural joint. The aim of this study was to develop and validate a porcine kne...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2015.07.043
更新日期:2015-09-18 00:00:00
abstract::Mathematical modelling of tendon thermodynamics predicted that the temperature of the central core of the equine superficial digital flexor tendon would plateau at 11 degrees C above the tendon surface temperature during a sustained gallop. A mean temperature differential (between tendon core and surface) of 5.4 (S.E....
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(94)90262-3
更新日期:1994-07-01 00:00:00
abstract::Motion capture systems are widely used to measure human kinematics. Nevertheless, users must consider system errors when evaluating their results. Most validation techniques for these systems are based on relative distance and displacement measurements. In contrast, our study aimed to analyse the absolute volume accur...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2018.04.009
更新日期:2018-06-06 00:00:00
abstract::This study was mainly performed to investigate the effects of high maxillary expansion forces on the skull with fresh and thiel-fixed human skulls. The maxillary suture was not weakened except in one experiment. This study compares the strain measured on the zygomatic process of the skull with the results of a finite ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2010.02.002
更新日期:2010-05-07 00:00:00
abstract::Previous studies evaluated 3D human jaw movements using kinematic analysis systems during mouth opening, but information on the reliability of such measurements is still scarce. The purpose of this study was to analyze within- and between-session reliabilities, inter-rater reliability, standard error of measurement (S...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2017.09.038
更新日期:2017-11-07 00:00:00
abstract::One of the most popular methods to fabricate biomedical microfluidic devices is by using a soft-lithography technique. However, the fabrication of the moulds to produce microfluidic devices, such as SU-8 moulds, usually requires a cleanroom environment that can be quite costly. Therefore, many efforts have been made t...
journal_title:Journal of biomechanics
pub_type: 杂志文章,评审
doi:10.1016/j.jbiomech.2015.11.031
更新日期:2016-07-26 00:00:00
abstract::This numerical study assesses the influence of an oversized humeral hemiprosthesis with a larger medial offset on the mechanics of the shoulder with cuff tear arthropathy (CTA). Shoulder elevation in the scapular plane is performed, and a Seebauer Type IIa CTA is simulated: a massive rotator cuff tear, a proximal and ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2012.11.021
更新日期:2013-02-22 00:00:00
abstract::This paper describes the process used to generate lower limb kinematics during single limb stance phase of gait, using musculoskeletal modelling, muscle driven forward simulation and gradient based optimisation techniques (including design of experiment techniques). Initial inputs to the forward simulation process wer...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(01)00240-8
更新日期:2002-05-01 00:00:00
abstract::Continuum finite element (FE) models of bones have become a standard pre-clinical tool to estimate bone strength. These models are usually based on clinical CT scans and material properties assigned are chosen as isotropic based only on the density distribution. It has been shown, however, that trabecular bone elastic...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2013.07.042
更新日期:2013-09-27 00:00:00
abstract::With the aim of proposing modelling equations for the length, force and shortening velocity of the triceps brachii, an X-ray and biomechanical study was carried out on the elbow joint. Two series of three upper right limbs removed from cadavers were used. It allowed us to situate the articular rotational axis of the e...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(95)00032-1
更新日期:1996-02-01 00:00:00
abstract::The geometry of a typical adult human carotid bifurcation, complete with the sinus, was established from a study of a large number of angiograms. A rigid model was constructed from glass and investigations were performed under steady flow conditions using flow visualization techniques over a range of upstream Reynolds...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(82)90057-4
更新日期:1982-01-01 00:00:00
abstract::An experimental study was carried out on asymmetrical abdominal aortic aneurysm (AAA) to analyse the physiological flows involved. Velocity measurements were performed using particle image velocimetry. Resting and exercise flow rates were investigated in models with rigid and compliant walls to assess the parameters a...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2006.11.017
更新日期:2007-01-01 00:00:00
abstract::Tripping over obstacles is the most frequently mentioned causes of falls. Thus, this study was performed to test the hypotheses that when crossing obstacles, toe-obstacle clearance and the three-dimensional motions and moments at the hip, knee, and ankle of the trailing limb (limb crossing the obstacle last) increase ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(96)00161-3
更新日期:1997-04-01 00:00:00
abstract::A finite element model of a bioprosthetic heart valve was developed to determine the influence of the stent height on leaflet stresses under various pressure loading conditions after valve closure. A nonlinear solution was used to obtain the stresses in the leaflets for stent heights of 14.6 mm, 19.0 mm and 22.0 mm re...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(86)90199-5
更新日期:1986-01-01 00:00:00
abstract::Age-related changes in bone quality are mainly manifested in the reduced toughness. Since the post-yield deformation of bone is realized through microdamage formation (e.g., microcracking and diffuse damage), it is necessary to understand the mechanism of microdamage formation in bone in order to elucidate underlying ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2005.01.009
更新日期:2006-01-01 00:00:00
abstract::The aim of the present study was to develop a Hill type muscle model that accounts for the effects of shortening history. For this purpose, a function was derived that relates force depression to starting length, shortening amplitude and contraction velocity. History parameters were determined from short-range isokine...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(98)00048-7
更新日期:1998-06-01 00:00:00
abstract::The aims of this study were: 1. To study the transfer of energy between the high bar and the gymnast. 2. To develop criteria from the utilisation of high bar elasticity and the utilisation of muscle capacity to assess the effectiveness of a movement solution. 3. To study the influence of varying segment movement upon ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(98)00134-1
更新日期:1998-12-01 00:00:00
abstract::Previous models to predict breast movement whilst performing physical activities have, erroneously, assumed uniform elasticity within the breast. Consequently, the predicted displacements have not yet been satisfactorily validated. In this study, real time motion capture of the natural vibrations of a breast that foll...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2017.11.027
更新日期:2018-01-23 00:00:00
abstract::For the purpose of detecting early aberrations of gait in rheumatoid arthritis 17 women suffering from that disease were examined. They were all under 50 years of age and had an essentially normal range of motility in the hips, knees and ankles. Eleven healthy women walking at voluntary speed and 6 healthy women walki...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(88)90237-0
更新日期:1988-01-01 00:00:00
abstract::The estimation of the skeletal motion obtained from marker-based motion capture systems is known to be affected by significant bias caused by skin movement artifacts, which affects joint center and rotation axis estimation. Among different techniques proposed in the literature, that based on rigid body model, still th...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2004.09.032
更新日期:2005-11-01 00:00:00