Abstract:
BACKGROUND:Atherosclerosis is a generalized disease of the arterial vasculature; among thus it manifests in the descending aorta and the coronary arteries. We tested whether known risk factors, the coronary flow velocity reserve and the grade of aortic atherosclerosis detected by transoesophageal echocardiography in the course of the same semi-invasive examination is able to distinguish between patients with significant left anterior descending coronary artery (LAD) stenosis or with multivessel disease. METHODS AND RESULTS:The present study involved 125 consecutive patients (mean age: 56 +/- 11 years, range: 22-73) with chest pain undergoing coronary angiography. Grade of aortic atherosclerosis was obtained by means of transoesophageal echocardiography, and the coronary flow velocity reserve was calculated in the left anterior descending coronary artery. The age (ROC area, 63%, p<0.01), the gender (ROC area, 63%, p<0.02) and the grade of aortic atherosclerosis (ROC area, 64%, p<0.01) exhibited good power for the prediction of patients with multivessel disease from among all other patients. Only the grade of aortic atherosclerosis (ROC area, 63%, p<0.05) appears useful to distinguish patients with left anterior descending coronary artery disease from those with multivessel disease. CONCLUSIONS:These results demonstrate that grade of aortic atherosclerosis furnishes additional help in the prediction of patients with severe coronary artery disease. It can differentiate patients with multivessel disease from those with significant left anterior descending coronary artery stenosis. Coronary flow velocity reserve has no any prognostic power in this evaluation.
journal_name
Ups J Med Scijournal_title
Upsala journal of medical sciencesauthors
Nemes A,Thury A,Forster T,Boda K,Csanády Mdoi
10.3109/2000-1967-097subject
Has Abstractpub_date
2007-01-01 00:00:00pages
73-82issue
1eissn
0300-9734issn
2000-1967pii
http://urn.kb.se/resolve?urn=urn:nbn:se:pub:diva-9journal_volume
112pub_type
杂志文章abstract::Platelet-derived growth factor B (PDGF-B) is a growth factor promoting and regulating cell migration, proliferation, and differentiation, involved in both developmental processes and in maintaining tissue homeostasis under strict regulation. What are the implications of prolonged or uncontrolled growth factor signalin...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2012.654860
更新日期:2012-05-01 00:00:00
abstract::Early discharge, defined as hospital leave 24-48 hours after birth, was introduced at Falun Hospital in 1984. 164 women interested in participating in an evaluative study of the program were randomly allocated in late pregnancy to an Experimental group (EG) offered early discharge, and a Control group (CG) offered the...
journal_title:Upsala journal of medical sciences
pub_type: 临床试验,杂志文章,随机对照试验,评审
doi:10.3109/03009738709178701
更新日期:1987-01-01 00:00:00
abstract::Local heat trauma was induced in rats with alloxan diabetes of 3 days duration. Zinc and copper concentrations in serum, liver, heart and pancreas were estimated. After traumatization there was a decrease of the serum zinc concentration in all animals. The lowest concentration was found in the diabetic animals. Serum ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738009179172
更新日期:1980-01-01 00:00:00
abstract::The lipid metabolism of isolated mouse pancreatic islets, which had been cultured for one week at 3.3 or 16.7 mM glucose, was examined in short-term experiments performed at the end of the culture period. It was found that: a) high-glucose cultured islets oxidized palmitate at a higher rate: and b) both groups of cult...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738109179210
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:Non-contrast computed tomography (NCT) has become an important diagnostic tool in acute abdominal pain, but the drawback is the increased radiation dose compared to abdominal plain film (APF). PURPOSE:To evaluate whether NCT, including low-dose computed tomography (LDCT, using 50 mAs), provides more diagnos...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009730903294871
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Shoulder external rotation braces used for patients with a first-time shoulder dislocation are designed with a variety of arm positions in abduction as well as external rotation. However, few studies have focused on their immobilizing performance, comfort, or user-friendliness. Especially, there have been no...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2012.744374
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVES:The incidence of fentanyl-induced cough (FIC) during induction of general anesthesia varies around 40% and is undesirable. It increases intracranial, intraocular, and intra-abdominal pressures. This prospective, randomized, double-blind, placebo-controlled study evaluated the effect of dexmedetomidine (DEX) ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,随机对照试验
doi:10.3109/03009734.2011.629749
更新日期:2012-03-01 00:00:00
abstract::In early ARDS (Adult Respiratory Distress Syndrome) and other inflammatory pulmonary disorders the lung might benefit from a high local deposition of an active drug, in order to optimize the local concentration without systemic side effects. In this methodological study we used pigs under controlled ventilation. The s...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009739009178581
更新日期:1990-01-01 00:00:00
abstract::A new stimulatory luteinizing hormone-releasing hormone (LRH) analogue D-Ser(TBU)(6)-EA(10)-LRH was administered subcutaneously in a dose of 10 microg into 10 women with amenorrhoea. The injection resulted in a 20-fold increase of the LH level in blood and a 5-fold increase of the FSH level with maxima at 4 and 6 h af...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737709179054
更新日期:1977-01-01 00:00:00
abstract::Twenty-seven women with secondary amenorrhoea have been treated with pulsatile subcutaneous luteinising hormone releasing hormone (LHRH). Serial ultrasonic observations of increasing follicular diameters and changes in the size of the uterus have been recorded. The rate of the increase of the diameter of dominant foll...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738409178460
更新日期:1984-01-01 00:00:00
abstract::The acute phase reaction is an unspecific response to inflammatory stimuli characterized by alterations in the concentration of several plasma proteins. It is of great clinical value to monitor the inflammatory state in patients with rheumatoid arthritis. The erythrocyte sedimentation rate (ESR) and C-reactive protein...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009739809178943
更新日期:1998-01-01 00:00:00
abstract::The purpose of this study is to verify that compound muscle action potentials (CMAPs) generated a stationary potential and to examine extension of the CMAPs away from the stimulated muscle. A referential derivation and/or bipolar derivation to record the stationary potentials were carried out following tibial nerve st...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-103
更新日期:2004-01-01 00:00:00
abstract:INTRODUCTION:Research about pregnancy-planning behaviour mostly focuses on women, even though pregnancy planning usually also concerns men. The purpose of this study was to investigate how men plan for family, and to measure their fertility knowledge after having become fathers. MATERIAL AND METHODS:Data were collecte...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.1080/03009734.2017.1316531
更新日期:2017-06-01 00:00:00
abstract::Different methodological aspects on the assay of human erythrocyte catechol-O-methyltransferase (COMT) activity were studied. No temporal variations were found either over a 24 hour period or over one month. Erythrocytes from whole blood collected with any of the anticoagulants heparin, EDTA or citrate could be used a...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738109179242
更新日期:1981-01-01 00:00:00
abstract::Different pharmacokinetic models for target controlled infusion (TCI) of propofol are available in the recently launched open TCI systems. There is also a compelling choice to work with either plasma- or effect-site targets. Knowledge about the clinical consequences of different alternatives is of importance. We aimed...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-222
更新日期:2008-01-01 00:00:00
abstract::During the last decade, capillary electrophoresis (CE) has emerged as an interesting alternative to traditional analysis of serum, plasma and urine proteins by agarose gel electrophoresis. Initially there was a considerable difference in resolution between the two methods but the quality of CE has improved significant...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-219
更新日期:2008-01-01 00:00:00
abstract::Despite the fact that the composition of urine varies a lot during the day, this has essentially been neglected as a factor of importance in determinations of urine bicarbonate. The investigations reviewed in combination with an own study shows that qualitative and quantitative factors in urine composition impacts the...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738209178420
更新日期:1982-01-01 00:00:00
abstract::One hundred and fifty women with a diagnosis of toxaemia of pregnancy treated in the Department of Obstetrics and Gynaecology, University Hospital, Uppsala between 1964 and 1968 were investigated. One hundred women were still living in the area in 1975 and thus could be restudied. The participation rate was 100% in th...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737809179119
更新日期:1978-01-01 00:00:00
abstract:AIM:To gain a deeper understanding of first-time parents' experiences of early discharge from hospital after delivery and home-based postnatal care. MATERIAL AND METHODS:The study was comprised of focus group interviews, interviews with couples and with fathers. Twenty-one parents participated. INCLUSION CRITERIA:hea...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009730903431809
更新日期:2010-05-01 00:00:00
abstract::The diagnostic distribution and the relation between diagnosis and symptoms, symptom duration, tumour site, tumour size and breast size were studied in 1 244 women with breast symptoms examined at a special breast tumour clinic. 9% of the women had cancer, 62% fibroadenosis and 6% fibroadenoma. In 18% no breast diseas...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737609179022
更新日期:1976-01-01 00:00:00
abstract::In Uppsala, extensive epidemiological and clinical studies on insulin resistance and diabetes have been ongoing for the past 30 years. A prospective cohort study of men born 1920-24, living in Uppsala County, was initiated during 1969-74 (the Uppsala Longitudinal Study of Adult Men, ULSAM). Risk factors for cardiovasc...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,评审
doi:10.1517/03009734000000060
更新日期:2000-01-01 00:00:00
abstract::Inverse ratio ventilation (IRV) is commonly used in clinical practice. Several studies have used IRV in order to recruit collapsed alveoli. In a randomised trial in twelve surfactant depleted piglets, the lungs were ventilated with sufficient positive end-expiratory pressure (PEEP) to prevent end-expiratory collapse, ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009739609178925
更新日期:1996-01-01 00:00:00
abstract::Factors that may influence the water transport through the skin in infants on their first day of life were studied with a method based on determination of the vapour pressure gradient in the air layer close to the skin surface. The evaporation rate from the skin was found to vary with the site of measurement, ambient ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738109179207
更新日期:1981-01-01 00:00:00
abstract:AIM:The purpose was to assess the direct costs of screening for high blood pressure and blood glucose in dental care and of follow-up in primary health care and, based on these data, arrive at a prediction function. Study population. All subjects coming for routine check-ups at three dental health clinics were invited ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,多中心研究
doi:10.3109/03009734.2013.818599
更新日期:2013-11-01 00:00:00
abstract::Vasospastic reactions to cold have been suggested to be related to altered blood rheology, as has been reported in both primary (PVD) and traumatic (TVD) vasospastic disease. Measurements of whole blood viscosity, plasma viscosity, erythrocyte deformability and finger systolic pressure (FSP) were performed in 18 patie...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738509178639
更新日期:1985-01-01 00:00:00
abstract::The occurrence of bacteriuria in spinal cord injured patients with neurogenic bladder dysfunction who used clean intermittent catheterisation to empty their bladders was studied in order to examine cut-off concentration breakpoints for significant bacteriuria in this group of patients using procedures of the European ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-107
更新日期:2004-01-01 00:00:00
abstract::SAPHO syndrome is a group of bone and joint abnormalities associated with skin lesions. A 29-year-old male presented with severe acne on his trunk and anterior chest wall, right knee and foot pain. Radiographs and magnetic resonance images showed hyperostosis in the sternocostoclavicular region, sclerosis of one-third...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-045
更新日期:2006-01-01 00:00:00
abstract::Radical surgery for renal cancer with invasion of the inferior vena cava can improve the patient's quality of life and, in some cases, offer longer survival or even cure. With a carefully planned surgical approach it is possible to remove renal tumours with thrombotic extension to the most proximal part of the inferio...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738509178646
更新日期:1985-01-01 00:00:00
abstract:AIM:The aim of this study was to describe content and procedures in some selected Swedish health care quality registries (QRs) of relevance to regulatory decision-making. METHODS:A workshop was organized with participation of seven Swedish QRs which subsequently answered a questionnaire regarding registry content on d...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.1080/03009734.2017.1285837
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Whether written feedback on drug prescribing in general practice affects prescribing habits is controversial. Most short-term studies showed no effect. However, the issue has not been tested in long-term studies involving the local general practitioner community. AIMS OF THE STUDY:To assess whether prescrib...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2010.487165
更新日期:2010-11-01 00:00:00