Highly purified omega-3 polyunsaturated fatty acids in clinical development.

abstract：BACKGROUND:The beta-adrenergic receptors of the myocardium play an important role in the regulation of heart function. The beta-adrenergic receptors belong to the family of G-protein coupled receptors. Three subtypes have been distinguished (beta1-, beta2-, and beta3-adrenoceptors). The receptors consist of seven membr...

journal_title：Herz

authors： Wallukat G

更新日期：2002-11-01 00:00:00

abstract：:Hydralazine is a smooth muscle relaxant and a potent arteriolar dilator. The major hemodynamic effect of hydralazine in patients with heart failure are increased cardiac output and stroke volume, and decreased vascular resistance without any significant change in pulmonary and systemic venous pressure. Hydralazine als...

journal_title：Herz

authors： Chatterjee K

更新日期：1983-08-01 00:00:00

abstract：CASE REPORT:A 41-year-old male saw his general practitioner because of progressive atypical angina symptoms and palpitations for the last 7 years. Chest X-ray showed a mediastinal mass. Further investigation by computed tomography (CT), magnetic resonance imaging (MRI) and cardiac catheterization revealed two bronchoge...

journal_title：Herz

authors： Kusch B,Vogt S,Rybinski L,Moosdorf R

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:The objective of the present review was to investigate the cost-effectiveness of second-generation drug-eluting stents (DES) compared to bare metal stents (BMS) as well as to first-generation DES. METHODS:A structured literature review in MEDLINE was conducted to identify all studies investigating the cost-...

journal_title：Herz

authors： Müller-Riemenschneider F,Reinhold T,Willich SN

更新日期：2011-05-01 00:00:00

abstract：:Marfan syndrome is a hereditary disease with a prevalence of 2-3 in 10,000 births, leading to a fibrillin connective tissue disorder with manifestations in the skeleton, eye, skin, dura mater and in particular the cardiovascular system. Since other syndromes demonstrate similar vascular manifestations, but therapy may...

journal_title：Herz

authors： Kallenbach K,Schwill S,Karck M

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Cardiac involvement in Lyme disease, caused by the tick-borne spirochete Borrelia burgdorferi, has been reported to occur in 0.3-4 % of infected patients in Europe. Cardiac manifestations may include conduction disturbances, and also myocarditis, pericarditis, and left ventricular dysfunction. We investigate...

journal_title：Herz

authors： Karatolios K,Maisch B,Pankuweit S

更新日期：2015-03-01 00:00:00

abstract：:The efficacy and tolerance of the standardized hawthorn (crataegus) extract WS 1442 were tested in a multicenter utilization observational study. We monitored 1,011 patients with cardiac insufficiency stage NYHA II, treated with this extract (Crataegutt novo 450, 1 tablet b.i.d.) over a period of 24 weeks. During and ...

journal_title：Herz

authors： Tauchert M,Gildor A,Lipinski J

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Once contraindicated, beta-blockers have become an established, evidence-based, recommended treatment concept in chronic heart failure during the last years. PATHOPHYSIOLOGY:The increased activation of the adrenergic system in heart failure syndrome, which leads to transmission of several adverse biological...

journal_title：Herz

authors： Hoffman J,Grimm W,Maisch B

更新日期：2002-03-01 00:00:00

abstract：:Atrial fibrillation represents the most common atrial arrhythmia seen in clinical practice. The surgical treatment of atrial fibrillation is recommended in symptomatic patients as well as in asymptomatic patients at low postoperative risk. As a "stand alone" procedure, surgical ablation therapy is indicated after fail...

journal_title：Herz

authors： Hanke T,Sievers HH

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND AIM OF THE STUDY:The predisposition to atrial fibrillation (AF) in mitral stenosis (MS) has been demonstrated with several electrocardiographic (increased P-wave dispersion) and echocardiographic parameters (atrial electromechanical delay). Despite the improvement in P-wave dispersion after percutaneous ...

journal_title：Herz

authors： Demirkan B,Guray Y,Guray U,Ege MR,Kisacik HL,Sasmaz H,Korkmaz S

更新日期：2013-03-01 00:00:00

abstract：:There is only a limited number of studies available comparing the effectiveness of various combinations of anti-ischemic and antianginal substances in the same patients with coronary artery disease and stable angina pectoris and even these are restricted to either only a few drugs or a single point in time for testing...

journal_title：Herz

authors： Lehmann G,Reiniger G,Wolf H,Beyerle A,Rudolph W

更新日期：1990-12-01 00:00:00

abstract：:Via the internet smartphones allow the download of applications ("Apps") that can address various requirements of daily life. These technical advances create new opportunities to better meet needs of patients suffering from hypertension. This may apply particularly for medication adherence, blood pressure control and ...

journal_title：Herz

authors： Becker S,Mitchell A,Königsmann T,Kribben A,Erbel R

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The endothelial lining is a confluent monolayer of thin and rhomboid-shaped cells, that covers the inner surface of all blood vessels. However, the essential role of endothelial cells in all aspects of cardiovascular physiology, homeostasis and the pathogenesis of most cardiovascular diseases no ...

journal_title：Herz

authors： Wilhelmi M,Leyh R,Haverich A

更新日期：2004-05-01 00:00:00

abstract：:In this investigation, we studied the feasibility of 3D-reconstruction from 2D cross-sectional intracoronary ultrasound images. A computer-aided, automated 3D-reconstruction was used to generate cylindrical and sagittal format of vessels in vitro (n = 9) and in vivo (n = 48). Ultrasound 2D-images were acquired with a ...

journal_title：Herz

authors： Ge J,Koch L,Roth T,Görge G,Kearney P,Haude M,Baumgart D,von Birgelen C,Brennecke R,Meyer J

更新日期：1995-08-01 00:00:00

abstract：:The tricuspid valve and the right ventricle are hemodynamically closely related. Pathological changes of the valve or of the ventricle itself and also various diseases beyond that can result in a downward spiral of mutual interference, which is of prognostic importance for the patient. The development of a functional ...

journal_title：Herz

authors： Edel C,Erbel R,Budde T

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Cardiac involvement may precede the onset of muscular manifestations in Becker muscular dystrophy (BMD), but Wolff-Parkinson-White (WPW) syndrome has not been reported as initial cardiac manifestation of BMD. CASE STUDY:In a 43-year-old, HIV-negative male, WPW syndrome was diagnosed at age 26 years upon a r...

journal_title：Herz

authors： Finsterer J,Stöllberger C,Quasthoff S

更新日期：2008-06-01 00:00:00

abstract：:In patients with chronic coronary artery disease different therapeutic strategies, such as optimal medical therapy, revascularization by percutaneous coronary intervention or coronary artery bypass grafting have been shown to improve the prognosis and symptoms and yield proven superiority over other treatment strategi...

journal_title：Herz

authors： de Waha S,Eitel I,Desch S,Fuernau G,Lurz P,Schuler G,Thiele H

更新日期：2013-06-01 00:00:00

abstract：:Acute heart failure is a symptom complex of heterogeneous etiology. Clinically, it comprises a broad spectrum ranging from hypertensive pulmonary edema in patients with preserved left ventricular systolic function up to cardiogenic shock in patients with severely depressed left ventricular function. The pathophysiolog...

journal_title：Herz

authors： Simonis G,Spitzer SG,Stumpf J,Dörr R

更新日期：2015-08-01 00:00:00

abstract：:The 12-lead surface electrocardiogram (ECG) is of great importance for the diagnostics of cardiac arrhythmias. For the correct and systematic analysis it has a sensitivity and specificity for the correct diagnosis of supraventricular tachycardia or ventricular tachycardia of more than 95%. Nevertheless, the assessment...

journal_title：Herz

authors： Trappe HJ

更新日期：2018-03-01 00:00:00

abstract：:Cardiac function, including the heart muscle and valves, can be severely altered by congenital and acquired heart diseases. Several graft materials are currently used to replace diseased cardiac tissue and valvular segments. Implantable grafts are either non-vital or can trigger an immune response which leads to graft...

journal_title：Herz

authors： Cebotari S,Tudorache I,Schilling T,Haverich A

更新日期：2010-08-01 00:00:00

abstract：:The aortic valve consists of three cusps attached to the wall of the aortic root. During the cardiac cycle, the aortic root undergoes complex movements that precede and aid opening and closing of the aortic valve. The aortic valve cusps themselves form thin-walled pocket-like structures, made from specialized tissue w...

journal_title：Herz

authors： Bechtel JF,Erasmi AW,Misfeld M,Sievers HH

更新日期：2006-08-01 00:00:00

abstract：:In congestive heart failure, acute administration of the converting enzyme inhibitor captopril leads to a decrease in arterial pressure, systemic vascular resistance, left ventricular filling pressure, and the end-diastolic volumes of both ventricles, as well as to an increase in cardiac index, stroke volume index, ri...

journal_title：Herz

authors： Massie BM,Kramer BL,Topic N

更新日期：1983-04-01 00:00:00

abstract：:Doppler echocardiography enables noninvasive determination of blood velocity and flow area through which quantitation of blood flow in vessels and across valvular orifices can be achieved. The stroke volume is rendered as the product of the flow area and the area beneath the velocity curve; on taking the heart rate in...

journal_title：Herz

authors： Zoghbi WA,Quinones MA

更新日期：1986-10-01 00:00:00

abstract：:Reducing cardiac mortality and improving quality of life are the main objectives of cardiac rehabilitation. In recent years, outpatient rehabilitation within easy patient reach has achieved the same status as inpatient rehabilitation. Outpatient rehabilitation permits close involvement of the patient's family and soci...

journal_title：Herz

authors： Fischer HM,Charrier A,Dörr R,Spitzer SG

更新日期：2012-02-01 00:00:00

abstract：UNLABELLED:INFLAMMATORY PROCESS: Within the vessel wall is considered to be crucial for initiation and progression of atherosclerosis. As response to endothelial injury a focal inflammatory response arises which can lead to plaque vulnerability and rupture and a consecutive acute coronary syndrome. Systemic markers of ...

journal_title：Herz

authors： Blankenberg S,Rupprecht HJ,Bickel C,Hafner G,Meyer J

更新日期：2001-04-01 00:00:00

abstract：:Of 89 children with angiographically-documented pulmonic stenosis and intact ventricular septum (PST), 76 (85.4%) had valvular, 11 (12.4%) infundibular and 2 (2%) had supravalvular lesions. Standard, p. a. view, chest X-rays of children with a mean age of 6 7/12 years were evaluated with respect to 1. cardiac enlargem...

journal_title：Herz

authors： Rautenburg HW,Askevold IB

更新日期：1980-10-01 00:00:00

abstract：PURPOSE:To determine predictors of patient radiation exposure due to percutaneous coronary interventions (PCI) and to compare our results with the "preliminary reference levels", recently proposed by the European DIMOND research cardiology group: i. e., 75 Gy.cm(2) for dose area kerma product (DAP), 17 min for fluorosc...

journal_title：Herz

authors： Kuon E,Empen K,Rohde D,Dahm JB

更新日期：2004-03-01 00:00:00

abstract：:To provide an overview of our experience with percutaneous balloon valvuloplasty in aortic stenosis, the results obtained in 218 patients have been analyzed. During the two years of its use, the technique of the procedure has been subsequently modified with increasing balloon diameters, initially 15 mm, 18 mm and then...

journal_title：Herz

authors： Cribier A,Letac B

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:Postcardiac injury syndrome (PCIS) is an inflammatory complication that derives from injury to the epicardium, myocardium, or endocardium. It occurs after trauma, myocardial infarction, percutaneous coronary intervention, cardiac surgery, intracardiac ablation, and implantation of cardiac implantable electro...

journal_title：Herz

authors： Filbey K,Sedaghat-Hamedani F,Kayvanpour E,Xynogalos P,Scherer D,Meder B,Katus HA,Zitron E

更新日期：2020-11-01 00:00:00

abstract：:In recent years we identified numerous cardiovascular risk factors and had been able to reduce cardiovascular events by a variety of different interventions. There is no question that we can improve the course of coronary artery disease (CAD) in patients with a high-risk profile by modifying these factors. Despite thi...

journal_title：Herz

authors： Schaefer JR,Simon B,Soufi M,Sattler A,Noll B,Herzum M,Maisch B

更新日期：2000-03-01 00:00:00