Plasma/serum proteomics: pre-analytical issues.

Abstract:

:High-throughput proteomics technologies tend to provide highly sensitive information about living tissues and biological fluids. Analytes are characterized by intrinsic and extrinsic properties, the latter depending on each phase of their preparation, sometimes adding artifacts with crucial repercussions in result reliability and interpretation. This review aims to address some issues that can be encountered when handling plasma and serum in experimental and clinical proteomic settings.

journal_name

Expert Rev Proteomics

authors

Barelli S,Crettaz D,Thadikkaran L,Rubin O,Tissot JD

doi

10.1586/14789450.4.3.363

subject

Has Abstract

pub_date

2007-06-01 00:00:00

pages

363-70

issue

3

eissn

1478-9450

issn

1744-8387

journal_volume

4

pub_type

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