Portal hypertension due to portal venous thrombosis: etiology, clinical outcomes.

abstract：AIM:To investigate the anti-diabetogenic mechanism of Nardostachys jatamansi extract (NJE). METHODS:Mice were injected with streptozotocin via a tail vein to induce diabetes. Rat insulinoma RINm5F cells and isolated rat islets were treated with interleukin-1beta and interferon-gamma to induce cytotoxicity. RESULTS:Tr...

journal_title：World journal of gastroenterology

authors： Song MY,Bae UJ,Lee BH,Kwon KB,Seo EA,Park SJ,Kim MS,Song HJ,Kwon KS,Park JW,Ryu DG,Park BH

更新日期：2010-07-14 00:00:00

abstract：:INTRODUCTION:To intrestigate the relationship between tumor necrosis factor-alphaand liver fibrosis in patients with chronic liver disease.METHODS:Radioimmunoassay was made in 20 patients with mild chronic hepatitis(CMH),20 patients with severe chronic hepatitis(CSH),51 patients with liver cirrhosis(LC)and 32-normal p...

journal_title：World journal of gastroenterology

authors： Wang X,Chen YX,Xu CF,Zhao GN,Huang YX,Wang QL

更新日期：1998-02-01 00:00:00

abstract：AIM:To examine fibrinogen-like protein 2 (fgl2) expression during taurocholate-induced acute pancreatitis progression in rats and its correlation with pancreatic injury severity. METHODS:Forty-eight male Sprague-Dawley rats were randomly divided into the severe acute pancreatitis (SAP) group (n = 24) and the sham oper...

journal_title：World journal of gastroenterology

authors： Ye XH,Chen TZ,Huai JP,Lu GR,Zhuge XJ,Chen RP,Chen WJ,Wang C,Huang ZM

更新日期：2013-04-28 00:00:00

abstract：AIM:To evaluate the risk factors-other than nonsteroidal anti-inflammatory drugs-for colonic diverticular bleeding in a westernized population. METHODS:One hundred and forty patients, treated for symptomatic diverticular disease in a community based hospital, were included. Thirty (21%) had signs of diverticular bleed...

journal_title：World journal of gastroenterology

authors： Jansen A,Harenberg S,Grenda U,Elsing C

更新日期：2009-01-28 00:00:00

abstract：AIM:To assess the usefulness of contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) for lymph node metastasis in pancreatobiliary carcinoma. METHODS:All patients suspected of pancreatobiliary carcinoma with visible lymph nodes after standard EUS between June, 2009 and January, 2012 were enrolled. In the pri...

journal_title：World journal of gastroenterology

authors： Miyata T,Kitano M,Omoto S,Kadosaka K,Kamata K,Imai H,Sakamoto H,Nisida N,Harwani Y,Murakami T,Takeyama Y,Chiba Y,Kudo M

更新日期：2016-03-28 00:00:00

abstract：BACKGROUND:The human microRNA 375 (MIR375) is significantly downregulated in human colorectal cancer (CRC) and we have previously shown that MIR375 is a CRC-associated miRNA. The metadherin (MTDH) is a candidate target gene of MIR375. AIM:To investigate the interaction and function between MIR375 and MTDH in human CRC...

journal_title：World journal of gastroenterology

authors： Han SH,Mo JS,Park WC,Chae SC

更新日期：2019-11-28 00:00:00

abstract：AIM:H101, an E1B 55 kD gene deleted adenovirus, has been shown to possess oncolysis activity experimentally and proved to be safe in preliminary phase I study. The current study was designed to evaluate its anti-tumor activity and toxicity in combination with chemotherapy in patients with late stage cancers. METHODS:H...

journal_title：World journal of gastroenterology

authors： Lu W,Zheng S,Li XF,Huang JJ,Zheng X,Li Z

更新日期：2004-12-15 00:00:00

abstract：AIM:To unravel the differences between systematic inflammatory response syndrome (SIRS) of acute pancreatitis compared to the same syndrome in sepsis. METHODS:Twenty-five patients were enrolled, 12 with sepsis and 13 acute pancreatitis. After diagnosis 20 mL blood was sampled. Half were assayed for isolation of monocy...

journal_title：World journal of gastroenterology

authors： Koussoulas V,Tzivras M,Karagianni V,Spyridaki E,Plachouras D,Giamarellou H,Giamarellos-Bourboulis EJ

更新日期：2006-11-07 00:00:00

abstract：AIM:To investigate the acute toxicity, phytochemical profile, antidiarrheal activity and mechanisms of action of Maytenus erythroxylon (M. erythroxylon) ethanol extract. METHODS:A castor oil-induced diarrhea model was used to evaluate antidiarrheal activity. Intestinal transit and gastric emptying protocols were used ...

journal_title：World journal of gastroenterology

authors： Formiga RO,Quirino ZGM,Diniz MFFM,Marinho AF,Tavares JF,Batista LM

更新日期：2017-06-28 00:00:00

abstract：AIM:To clarify the role of serum anti-Helicobacter pylori (H. pylori) antibody titers in gastric cancer. METHODS:In this cross-sectional study, the effect of patients' baseline characteristics and endoscopic findings on their serum antibody titers were assessed. We evaluated consecutive patients who underwent esophago...

journal_title：World journal of gastroenterology

authors： Toyoshima O,Nishizawa T,Sakitani K,Yamakawa T,Takahashi Y,Yamamichi N,Hata K,Seto Y,Koike K,Watanabe H,Suzuki H

更新日期：2018-09-21 00:00:00

abstract：AIM:To reviewing genetic and epigenetic make-up of metastatic colorectal cancers (mCRCs) addicted to epidermal growth factor receptor (EGFR) signalling. METHODS:The present study summarizes the potential value of prognostic and predictive biomarkers in selecting mCRC patients treated with anti-EGFR therapy. A meta-ana...

journal_title：World journal of gastroenterology

authors： Lo Nigro C,Ricci V,Vivenza D,Granetto C,Fabozzi T,Miraglio E,Merlano MC

更新日期：2016-08-14 00:00:00

abstract：:A 41-year-old man with a continuous-flow left ventricular assist device presented for evaluation of dysphagia and dark urine. He was found to have a significantly elevated L-lactate dehydrogenase and an elevated plasma free hemoglobin consistent with intravascular hemolysis. After the hemolysis ceased, both the black ...

journal_title：World journal of gastroenterology

authors： Wuschek A,Iqbal S,Estep J,Quigley E,Richards D

更新日期：2015-05-14 00:00:00

abstract：AIM:To clarify the association of glypican-3 (GPC3) expression with Wnt and other growth signaling molecules in hepatocellular carcinoma (HCC). METHODS:Expression of GPC3, Wnt, matrix metalloproteinases (MMPs), sulfatase (SULF)1, SULF2, and other growth signaling molecules was analyzed in HCC cell lines and tissue sam...

journal_title：World journal of gastroenterology

authors： Akutsu N,Yamamoto H,Sasaki S,Taniguchi H,Arimura Y,Imai K,Shinomura Y

更新日期：2010-07-28 00:00:00

abstract：:Castleman's disease (CD) is a rare lymphoproliferative disorder of unknown etiology. Clinically, it occurs as a localized (unicentric) disease or as a systemic (multicentric) disease. Unicentric Castleman's disease (UCD) presents as a solitary mass and primarily affects the mediastinal, retroperitoneal, and cervical l...

journal_title：World journal of gastroenterology

authors： Lee HJ,Jeon HJ,Park SG,Park CY

更新日期：2015-02-07 00:00:00

abstract：AIM:To enhance the clinical utility of electrogastrography (EGG), which has been recorded since 1922, but is clinically unutilized. METHODS:An innovative method to salvage the promise of EGG is proposed by introducing a preliminary procedure, while maintaining the electrodes, standardized equipment, and signal process...

journal_title：World journal of gastroenterology

authors： Poscente MD,Mintchev MP

更新日期：2017-07-07 00:00:00

abstract：:AIM:To explore the status of extrahepatic hepatitis C virus (HCV) infection and replication in hepatitis C patients,and its potential implication in HCV infection and pathogenicity.METHODS:By reverse-transcriptase poly-merase chain reaction (RT-PCR),in situ hybridization (ISH) and immunohis-tochemistry, HCV RNA, HCV r...

journal_title：World journal of gastroenterology

authors： Yan FM,Chen AS,Hao F,Zhao XP,Gu CH,Zhao LB,Yang DL,Hao LJ

更新日期：2000-12-01 00:00:00

abstract：AIM:To assess numbers and case fatality of patients with upper gastrointestinal bleeding (UGIB), effects of deprivation and whether weekend presentation affected outcomes. METHODS:Data was obtained from Information Services Division (ISD) Scotland and National Records of Scotland (NRS) death records for a ten year per...

journal_title：World journal of gastroenterology

authors： Ahmed A,Armstrong M,Robertson I,Morris AJ,Blatchford O,Stanley AJ

更新日期：2015-10-14 00:00:00

abstract：AIM:To investigate the effect of integrin-linked kinase (ILK) on proliferation, metastasis, and invasion of the colorectal cancer cell line SW480. METHODS:In this study, the colorectal cancer cell line SW480 was stably transfected with ILK plasmids, and small interfering RNA (siRNA) was used to knockdown expression of...

journal_title：World journal of gastroenterology

authors： Shen H,Ma JL,Zhang Y,Deng GL,Qu YL,Wu XL,He JX,Zhang S,Zeng S

更新日期：2016-04-21 00:00:00

abstract：:A 33-year-old woman who presented with epigastric discomfort and diarrhea underwent an abdominal ultrasound (US). This investigation and subsequent contrast-enhanced computed tomography, magnetic resonance imaging and endoscopic US with fine needle aspiration (FNA) revealed a 40 mm well-circumscribed mass in the uncin...

journal_title：World journal of gastroenterology

authors： Poves I,Burdío F,Iglesias M,Martínez-Serrano Mde L,Aguilar G,Grande L

更新日期：2009-09-14 00:00:00

abstract：AIM:To characterize AXL receptor tyrosine kinase (AXL) expression in relationship to tumor protein P53 (TP53 gene, p53 protein) and its role in tumor invasion and response to therapy. METHODS:We used 14 cell lines, including 3 isogenic pairs carrying mutant/knockout p53, to gain insight into the relationship between A...

journal_title：World journal of gastroenterology

authors： Abdel-Rahman WM,Al-Khayyal NA,Nair VA,Aravind SR,Saber-Ayad M

更新日期：2017-05-21 00:00:00

abstract：:A variety of hepatic and biliary tract disorders may complicate the clinical course of celiac disease. Some of these have been hypothesized to share common genetic factors or have a common immunopathogenesis, such as primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune forms of hepatitis or cholang...

journal_title：World journal of gastroenterology

authors： Freeman HJ

更新日期：2006-03-14 00:00:00

abstract：AIM:To clarify the effect of a high des-gamma-carboxy prothrombin (DCP) level on the invasiveness and prognosis of small hepatocellular carcinoma. METHODS:Among 142 consecutive patients with known DCP levels, who underwent hepatectomy because of hepatocellular carcinoma, 85 patients met the criteria for small hepatoce...

journal_title：World journal of gastroenterology

authors： Hakamada K,Kimura N,Miura T,Morohashi H,Ishido K,Nara M,Toyoki Y,Narumi S,Sasaki M

更新日期：2008-03-07 00:00:00

abstract：AIM:To investigate urotensin-II (UII) and its effects on tumor necrosis factor (TNF)-α and interleukin (IL)-1β in early acute liver failure (ALF). METHODS:We investigated the time-dependent alteration in UII levels and its effects on TNF-α and IL-1β in liver and blood in the early stage of lipopolysaccharide/D-galacto...

journal_title：World journal of gastroenterology

authors： Liu LM,Zhao L,Liang DY,Yu FP,Ye CG,Tu WJ,Zhu T

更新日期：2015-03-21 00:00:00

abstract：AIM:To explore the virulence and the potential pathogenicity of coccoid Helicobacter pylori (H. pylori) transformed from spiral form by exposure to antibiotic. METHODS:Three strains of H. pylori, isolated from gastric biopsy specimens of confirmed peptic ulcer, were converted from spiral into coccoid from by exposure ...

journal_title：World journal of gastroenterology

authors： She FF,Su DH,Lin JY,Zhou LY

更新日期：2001-04-01 00:00:00

abstract：:Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. The identification of colonic polyps can reduce CRC mortality through earlier diagnosis of cancers and the removal of polyps: the precursor lesion of CRC. Following the finding and removal of colonic polyps at an initial colonoscopy, some p...

journal_title：World journal of gastroenterology

authors： Bonnington SN,Rutter MD

更新日期：2016-02-14 00:00:00

abstract：:We report a case of two pseudolymphomas of the liver in a 63-year-old Japanese woman with primary biliary cirrhosis. One of the lesions was found incidentally during a medical examination, presenting as a 10 mm hypodense nodule that revealed hyperdensity in the early phase and hypodensity in the late phase in computed...

journal_title：World journal of gastroenterology

authors： Okada T,Mibayashi H,Hasatani K,Hayashi Y,Tsuji S,Kaneko Y,Yoshimitsu M,Tani T,Zen Y,Yamagishi M

更新日期：2009-09-28 00:00:00

abstract：:Jejunoileal bypass (JIB), popular in the 1960s and 1970s, had remarkable success in achieving weight loss by creating a surgical short bowel syndrome. Our patient had an unusual case of liver disease and provided no history of prior bariatric surgery. Later, it was recognized that he had a JIB in the 1970s, which was ...

journal_title：World journal of gastroenterology

authors： Singh D,Laya AS,Clarkston WK,Allen MJ

更新日期：2009-05-14 00:00:00

abstract：AIM:To investigate the role of single nucleotide polymorphisms (SNPs) in CD24 gene in susceptibility and overall survival of gastric cancer (GC). METHODS:We genotyped 3 tagging SNPs of CD24-P-534 in the promoter region, P170 in the coding region of exon 2 and P1527 in the 3' untranslated region - using polymerase chai...

journal_title：World journal of gastroenterology

authors： Jia ZF,Wang LZ,Cao XY,Wang C,Cao DH,Wu X,You LL,Jin MS,Wang YP,Zhou BS,Jiang J

更新日期：2016-02-21 00:00:00

abstract：AIM:To investigate the frequency and risk factors for acute pancreatitis after pancreatic guidewire placement (P-GW) in achieving cannulation of the bile duct during endoscopic retrograde cholangio-pancreatography (ERCP). METHODS:P-GW was performed in 113 patients in whom cannulation of the bile duct was difficult. Th...

journal_title：World journal of gastroenterology

authors： Ito K,Fujita N,Noda Y,Kobayashi G,Obana T,Horaguchi J,Takasawa O,Koshita S,Kanno Y

更新日期：2008-09-28 00:00:00

abstract：:Hepatoid adenocarcinoma of the stomach (HAS) is a rare form of gastric cancer that has unique clinicopathological features and an extremely poor prognosis. Here, we report on three patients with suspected gastric cancer who were referred to our hospital. Gastrointestinal fiberscopy on the three patients revealed two l...

journal_title：World journal of gastroenterology

authors： Ye MF,Tao F,Liu F,Sun AJ

更新日期：2013-07-21 00:00:00