Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing.

abstract：BACKGROUND:Sugarcane is an economically important crop contributing to about 80% of the world sugar production. Increasing efforts in molecular biological studies have been performed for improving the sugar yield and other relevant important agronomic traits. However, due to sugarcane's complicated genomes, it is still...

journal_title：BMC genomics

authors： Zhang Q,Hu W,Zhu F,Wang L,Yu Q,Ming R,Zhang J

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Typhoid fever is an infectious disease of global importance that is caused by Salmonella enterica subsp. enterica serovar Typhi (S. Typhi). This disease causes an estimated 200,000 deaths per year and remains a serious global health threat. S. Typhi is strictly a human pathogen, and some recovered individual...

journal_title：BMC genomics

authors： Yap KP,Gan HM,Teh CS,Chai LC,Thong KL

更新日期：2014-11-20 00:00:00

abstract：BACKGROUND:Eucalyptus is one of the most important sources of industrial cellulose. Three species of this botanical group are intensively used in breeding programs: E. globulus, E. grandis and E. urophylla. E. globulus is adapted to subtropical/temperate areas and is considered a source of high-quality cellulose; E. gr...

journal_title：BMC genomics

authors： Salazar MM,Nascimento LC,Camargo EL,Gonçalves DC,Lepikson Neto J,Marques WL,Teixeira PJ,Mieczkowski P,Mondego JM,Carazzolle MF,Deckmann AC,Pereira GA

更新日期：2013-03-22 00:00:00

abstract：BACKGROUND:Midgut invasion, a major bottleneck for malaria parasites transmission is considered as a potential target for vector-parasite interaction studies. New intervention strategies are required to explore the midgut proteins and their potential role in refractoriness for malaria control in Anopheles mosquitoes. T...

journal_title：BMC genomics

authors： Vijay S,Rawal R,Kadian K,Singh J,Adak T,Sharma A

更新日期：2018-05-08 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are an abundant class of small single-stranded non-coding RNA molecules ranging from 18 to 24 nucleotides. They negatively regulate gene expression at the post-transcriptional level and play key roles in many biological processes, including skeletal development and cartilage maturation. In...

journal_title：BMC genomics

authors： Desjardin C,Vaiman A,Mata X,Legendre R,Laubier J,Kennedy SP,Laloe D,Barrey E,Jacques C,Cribiu EP,Schibler L

更新日期：2014-09-17 00:00:00

abstract：BACKGROUND:Phenylalanine ammonia lyase (PAL) is a key enzyme of the phenylpropanoid pathway that catalyzes the deamination of phenylalanine to trans-cinnamic acid, a precursor for the lignin and flavonoid biosynthetic pathways. To date, PAL genes have been less extensively studied in gymnosperms than in angiosperms. Ou...

journal_title：BMC genomics

authors： Bagal UR,Leebens-Mack JH,Lorenz WW,Dean JF

更新日期：2012-06-11 00:00:00

abstract：BACKGROUND:Health traits are of significant economic importance to the dairy industry due to their effects on milk production and associated treatment costs. Genome-wide association studies (GWAS) provide a means to identify associated genomic variants and thus reveal insights into the genetic architecture of complex t...

journal_title：BMC genomics

authors： Freebern E,Santos DJA,Fang L,Jiang J,Parker Gaddis KL,Liu GE,VanRaden PM,Maltecca C,Cole JB,Ma L

更新日期：2020-01-13 00:00:00

abstract：BACKGROUND:Frontotemporal lobar degeneration (FTLD) is a progressive neurodegenerative disorder that can be triggered through genetic or sporadic mechanisms. MicroRNAs (miRNAs) have become a major therapeutic focus as their pervasive expression and powerful regulatory roles in disease pathogenesis become increasingly a...

journal_title：BMC genomics

authors： Kocerha J,Kouri N,Baker M,Finch N,DeJesus-Hernandez M,Gonzalez J,Chidamparam K,Josephs KA,Boeve BF,Graff-Radford NR,Crook J,Dickson DW,Rademakers R

更新日期：2011-10-27 00:00:00

abstract：BACKGROUND:Transposable Elements (TEs) are key components that shape the organization and evolution of genomes. Fungi have developed defense mechanisms against TE invasion such as RIP (Repeat-Induced Point mutation), MIP (Methylation Induced Premeiotically) and Quelling (RNA interference). RIP inactivates repeated sequ...

journal_title：BMC genomics

authors： Amselem J,Lebrun MH,Quesneville H

更新日期：2015-02-28 00:00:00

abstract：BACKGROUND:Atlantic salmon production in Tasmania (Southern Australia) occurs near the upper limits of the species thermal tolerance. Summer water temperatures can average over 19 °C over several weeks and have negative effects on performance and health. Liver tissue exerts important metabolic functions in thermal adap...

journal_title：BMC genomics

authors： Nuez-Ortín WG,Carter CG,Nichols PD,Cooke IR,Wilson R

更新日期：2018-02-12 00:00:00

abstract：BACKGROUND:Recent studies have shown that human populations have experienced a complex demographic history, including a recent epoch of rapid population growth that led to an excess in the proportion of rare genetic variants in humans today. This excess can impact the burden of private mutations for each individual, de...

journal_title：BMC genomics

authors： Gao F,Keinan A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Aquaporins (AQPs), as members of the major intrinsic protein (MIP) superfamily, facilitated the permeation of water and other solutes and are involved in multiple biological processes. AQP family exists in almost all living organisms and is highly diversified in vertebrates in both classification and functio...

journal_title：BMC genomics

authors： Jia Y,Liu X

更新日期：2020-07-29 00:00:00

abstract：BACKGROUND:The sequencing of the cow genome was recently published (Btau_4.0 assembly). A second, alternate cow genome assembly (UMD2), based on the same raw sequence data, was also published. The two assemblies have been subsequently updated to Btau_4.2 and UMD3.1, respectively. RESULTS:We compared the Btau_4.2 and U...

journal_title：BMC genomics

authors： Partipilo G,D'Addabbo P,Lacalandra GM,Liu GE,Rocchi M

更新日期：2011-12-30 00:00:00

abstract：BACKGROUND:Chinese wild grapevine (Vitis amurensis) has remarkable cold stress tolerance, exceeding that of the common cultivated grapevine (Vitis vinifera L.). RESULT:Here, we surveyed the expression dynamics of microRNAs (miRNAs) across Chinese wild grapevine (cv. Beibinghong) and cultivated grapevine (cv. Cabernet ...

journal_title：BMC genomics

authors： Wang P,Yang Y,Shi H,Wang Y,Ren F

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:DNA methylation is a key modulator of gene expression in mammalian development and cellular differentiation, including neurons. To date, the role of DNA modifications in long-term potentiation (LTP) has not been explored. RESULTS:To investigate the occurrence of DNA methylation changes in LTP, we undertook ...

journal_title：BMC genomics

authors： Maag JL,Kaczorowski DC,Panja D,Peters TJ,Bramham CR,Wibrand K,Dinger ME

更新日期：2017-03-23 00:00:00

abstract：BACKGROUND:Codon usage analysis has been a classical topic for decades and has significances for studies of evolution, mRNA translation, and new gene discovery, etc. While the codon usage varies among different members of the plant kingdom, indicating the necessity for species-specific study, this work has mostly been ...

journal_title：BMC genomics

authors： Feng C,Xu CJ,Wang Y,Liu WL,Yin XR,Li X,Chen M,Chen KS

更新日期：2013-10-25 00:00:00

abstract：BACKGROUND:Banana and plantain (Musa spp.) comprise an important part of diets for millions of people around the globe. Low temperature is one of the key environmental stresses which greatly affects the global banana production. To understand the molecular mechanism of the cold-tolerance in plantain we used RNA-Seq bas...

journal_title：BMC genomics

authors： Yang QS,Gao J,He WD,Dou TX,Ding LJ,Wu JH,Li CY,Peng XX,Zhang S,Yi GJ

更新日期：2015-06-10 00:00:00

abstract：BACKGROUND:For centuries roses have been selected based on a number of traits. Little information exists on the genetic and molecular basis that contributes to these traits, mainly because information on expressed genes for this economically important ornamental plant is scarce. RESULTS:Here, we used a combination of ...

journal_title：BMC genomics

authors： Dubois A,Carrere S,Raymond O,Pouvreau B,Cottret L,Roccia A,Onesto JP,Sakr S,Atanassova R,Baudino S,Foucher F,Le Bris M,Gouzy J,Bendahmane M

更新日期：2012-11-20 00:00:00

abstract：BACKGROUND:Most of our understanding on the social behavior and genomics of bees and other social insects is centered on the Western honey bee, Apis mellifera. The genus Apis, however, is a highly derived branch comprising less than a dozen species, four of which genomically characterized. In contrast, for the equally ...

journal_title：BMC genomics

authors： de Paula Freitas FC,Lourenço AP,Nunes FMF,Paschoal AR,Abreu FCP,Barbin FO,Bataglia L,Cardoso-Júnior CAM,Cervoni MS,Silva SR,Dalarmi F,Del Lama MA,Depintor TS,Ferreira KM,Gória PS,Jaskot MC,Lago DC,Luna-Lucena D,Moda L

更新日期：2020-06-03 00:00:00

abstract：BACKGROUND:Much of the morphological diversity in eukaryotes results from differential regulation of gene expression in which transcription factors (TFs) play a central role. The nematode Caenorhabditis elegans is an established model organism for the study of the roles of TFs in controlling the spatiotemporal pattern ...

journal_title：BMC genomics

authors： Haerty W,Artieri C,Khezri N,Singh RS,Gupta BP

更新日期：2008-08-27 00:00:00

abstract：BACKGROUND:Mammalian genomes contain a large number (approximately 1000) of olfactory receptor (OR) genes, many of which (20 to 50%) are pseudogenes. OR gene transcription is not restricted to the olfactory epithelium, but is found in numerous tissues. Using microarray hybridization and RTqPCR, we analyzed the mRNA pro...

journal_title：BMC genomics

authors： Rimbault M,Robin S,Vaysse A,Galibert F

更新日期：2009-12-02 00:00:00

abstract：BACKGROUND:Because of the advent of high-throughput sequencing and the consequent reduction in the cost of sequencing, many organisms have been completely sequenced and most of their genes identified. It thus has become possible to represent whole genomes as ordered lists of gene identifiers and to study the rearrangem...

journal_title：BMC genomics

authors： Yue F,Zhang M,Tang J

更新日期：2008-09-16 00:00:00

abstract：BACKGROUND:Duchenne muscular dystrophy (DMD), caused by mutations in the dystrophin gene, is lethal. In contrast, dystrophin-deficient mdx mice recover due to effective regeneration of affected muscle tissue. To characterize the molecular processes associated with regeneration, we compared gene expression levels in hin...

journal_title：BMC genomics

authors： Turk R,Sterrenburg E,de Meijer EJ,van Ommen GJ,den Dunnen JT,'t Hoen PA

更新日期：2005-07-13 00:00:00

abstract：BACKGROUND:Understanding how and why genetic variation is partitioned across geographic space is of fundamental importance to understanding the nature of biological species. How geographical isolation and local adaptation contribute to the formation of ecotypically differentiated groups of plants is just beginning to b...

journal_title：BMC genomics

authors： Gould BA,Palacio-Mejia JD,Jenkins J,Mamidi S,Barry K,Schmutz J,Juenger TE,Lowry DB

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Systems biology and functional genomics require genome-wide datasets and resources. Complete sets of cloned open reading frames (ORFs) have been made for about a dozen bacterial species and allow researchers to express and study complete proteomes in a high-throughput fashion. RESULTS:We have constructed an...

journal_title：BMC genomics

authors： Rajagopala SV,Yamamoto N,Zweifel AE,Nakamichi T,Huang HK,Mendez-Rios JD,Franca-Koh J,Boorgula MP,Fujita K,Suzuki K,Hu JC,Wanner BL,Mori H,Uetz P

更新日期：2010-08-11 00:00:00

abstract：BACKGROUND:Butterflies and moths are emerging as model organisms in genetics and evolutionary studies. The family Hesperiidae (skippers) was traditionally viewed as a sister to other butterflies based on its moth-like morphology and darting flight habits with fast wing beats. However, DNA studies suggest that the famil...

journal_title：BMC genomics

authors： Cong Q,Borek D,Otwinowski Z,Grishin NV

更新日期：2015-08-27 00:00:00

abstract：BACKGROUND:The ascomycete fungus Ceratocystis cacaofunesta is the causal agent of wilt disease in cacao, which results in significant economic losses in the affected producing areas. Despite the economic importance of the Ceratocystis complex of species, no genomic data are available for any of its members. Given that ...

journal_title：BMC genomics

authors： Ambrosio AB,do Nascimento LC,Oliveira BV,Teixeira PJ,Tiburcio RA,Toledo Thomazella DP,Leme AF,Carazzolle MF,Vidal RO,Mieczkowski P,Meinhardt LW,Pereira GA,Cabrera OG

更新日期：2013-02-11 00:00:00

abstract：BACKGROUND:We performed large-scale bacterial artificial chromosome (BAC) end-sequencing of two BAC libraries (an EcoRI- and a BamHI-digested library) and conducted an in silico analysis to characterize the obtained sequence data, to make them a useful resource for genomic research on the silkworm (Bombyx mori). RESUL...

journal_title：BMC genomics

authors： Suetsugu Y,Minami H,Shimomura M,Sasanuma S,Narukawa J,Mita K,Yamamoto K

更新日期：2007-09-07 00:00:00

abstract：BACKGROUND:The host response to influenza A infections is strongly influenced by host genetic factors. Animal models of genetically diverse mouse strains are well suited to identify host genes involved in severe pathology, viral replication and immune responses. Here, we have utilized a dual RNAseq approach that allowe...

journal_title：BMC genomics

authors： Wilk E,Pandey AK,Leist SR,Hatesuer B,Preusse M,Pommerenke C,Wang J,Schughart K

更新日期：2015-09-02 00:00:00

abstract：BACKGROUND:Second generation sequencing has permitted detailed sequence characterisation at the whole genome level of a growing number of non-model organisms, but the data produced have short read-lengths and biased genome coverage leading to fragmented genome assemblies. The PacBio RS long-read sequencing platform off...

journal_title：BMC genomics

authors： Ferrarini M,Moretto M,Ward JA,Šurbanovski N,Stevanović V,Giongo L,Viola R,Cavalieri D,Velasco R,Cestaro A,Sargent DJ

更新日期：2013-10-01 00:00:00