Solitary myeloma with massive extracellular crystalline structures--a case report.

Abstract:

:We describe a case of solitary myeloma showing cystic change filled with massive crystalline structures in a 54-year-old woman. A bone X-ray showed a solitary cystic osteolytic lesion in the right iliac bone. Serum and urine protein electrophoresis showed no demonstrable M-protein, and bone-marrow aspirates did not show any myeloma cells. Histologic examination of the tumor revealed aggregation of plasma cells with massive extracellular infiltration of the rhomboid-shaped crystalline structures. In immunoperoxidase staining, both these crystalline structures and the cytoplasms of the myeloma cells demonstrated a positive reaction for lambda light chain. By electron microscope, the large extracellular crystalline structures were observed, and we found unique rhomboid or rectangular-shaped crystalline structures in the cytoplasms of the myeloma cells.

journal_name

J Korean Med Sci

authors

Kim YG,Yang KH,Gang SJ,Kim BK,Kim SM

doi

10.3346/jkms.1991.6.2.165

subject

Has Abstract

pub_date

1991-06-01 00:00:00

pages

165-71

issue

2

eissn

1011-8934

issn

1598-6357

journal_volume

6

pub_type

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