Intestinal endometriosis complicated by ileal perforation after initiation of gonadotropin-releasing hormone agonist therapy.

Abstract:

OBJECTIVE:To report a rare complication of GnRH agonist therapy for intestinal endometriosis. DESIGN:Case report. SETTING:University hospital. PATIENT(S):A 45-year-old nulliparous Japanese woman with catamenial digestive symptoms. INTERVENTION(S):GnRH agonist therapy. MAIN OUTCOME MEASURE(S):Acute abdomenal crisis with free air in the abdominal X-ray. RESULT(S):An emergency laparotomy showed both an ileal constriction and perforation. An ileocecal enterectomy with an end-to-end anastomosis was performed. A pathological examination of the ileum revealed ileal endometriosis. CONCLUSION(S):Flare-up of intestinal endometriosis induced by GnRH agonist has the potential to lead to intestinal perforation. Careful diagnosis and treatment are necessary for cyclic and periodic gastrointestinal manifestation.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Saito S,Murakami T,Suzuki K,Terada Y,Fukushima K,Moriya T

doi

10.1016/j.fertnstert.2006.12.082

subject

Has Abstract

pub_date

2007-10-01 00:00:00

pages

969.e7-9

issue

4

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(07)00103-3

journal_volume

88

pub_type

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