Abstract：
UNLABELLED:Iron supplementation programs using pediatric tablets or drops have not been successful in the control of anemia amongst infants and children in India. Sprinkles is an innovative multi-micronutrient home fortification strategy to control iron deficiency and anemia. OBJECTIVE:We aimed to determine the hematologic response to different doses and forms of iron in Sprinkles and iron drops. SETTING:Twenty two villages of Vadu Rural Health Program, KEM Hospital, Pune. DESIGN:Double blind clustered randomized community-based trial. SUBJECTS:Children (n=432) aged 6 to 18 mo age with Hb between 70 to 100 g/L were enrolled. METHODS:Selected villages were randomized into 5 groups: Sprinkles 12.5, 20 or 30 mg ferrous fumarate, Sprinkles 20 mg micronized ferric pyrophosphate or drops 20 mg ferrous glycine sulphate (DROPS) for 8 weeks. Household socio-demographic information was collected at baseline. Side effects and compliance were monitored through weekly visits. Hemoglobin was estimated at baseline, 3 and 8 weeks. Ferritin was assessed at baseline and 8 weeks. RESULTS:Baseline characteristics were similar across all groups. Hemoglobin increased significantly (P<0.0001) in all groups at 8 weeks with no difference between groups. Ferritin increased (P<0.0001) significantly in all groups with no difference across the groups. Compliance (overall range: 42 to 62 %) was lowest for DROPS. Side effects were significantly higher among DROPS compared to Sprinkles (p>0.05). CONCLUSIONS:Sprinkles 12.5 mg FF dose is as efficacious as higher doses of iron in Sprinkles or DROPS in increasing hemoglobin. Sprinkles FF 12.5 mg is recommended as it has fewer reported side effects and better compliance compared to DROPS.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Hirve S,Bhave S,Bavdekar A,Naik S,Pandit A,Schauer C,Christofides A,Hyder Z,Zlotkin Ssubject
Has Abstractpub_date
2007-02-01 00:00:00pages
91-100issue
2eissn
0019-6061issn
0974-7559journal_volume
44pub_type
杂志文章,随机对照试验abstract：:We conducted this double blind randomized controlled trial to compare the rapid bronchodilator effect of salmeterol and formoterol in 60 children with stable asthma. Participants were randomized to receive either salmeterol (50 microg) (n=31) or formoterol (24 microg) (n=29) by metered dose inhaler and spacer. Spirome...
journal_title：Indian pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2008-03-01 00:00:00
abstract：:We prospectively studied the effect of oral paracetamol in closing hemodynamically significant Patent ductus arteriosus in preterm infants (gestational age <32 weeks) where Ibuprofen was contraindicated. 29 of 40 neonates (72.5%) showed successful response while 11 (29.5%) failed to show any response. No major complic...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2016-02-01 00:00:00
abstract：:Fifty seven male children between ages of 10-16 years engaged in the brassware industry at Moradabad in Northern India were studied for occupational morbidity. The finding were compared with those obtained in the children (n = 29) engaged in other ancillary units which did not involve exposure to the metal fumes and d...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-02-01 00:00:00
abstract：OBJECTIVE:To compare lipid parameters between diabetics and controls and to study association between metabolic control and lipid profile. METHODS:Lipid profile and HbA1c were measured (n=80, 39 boys) in diabetic children [age 10.7(3.4) y] and 54 controls, tests repeated after 1 year (in 45 diabetics). RESULTS:Diabet...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0787-2
更新日期：2016-01-01 00:00:00
abstract：:In order to evaluate clinical and bacteriological efficacy of Cefpodoxime Proxetil (CP) in typhoid fever in comparison to cefixime (CF), we assessed 140 children with suspected typhoid fever. Fulfilling inclusion criteria finally 40 culture confirmed typhoid fever were allocated in randomized double blind clinical tri...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2007-11-01 00:00:00
abstract：OBJECTIVE:To estimate the prevalence of rotavirus diarrhea among hospitalized children less than 5 years of age in Kerala State and to determine the circulating strains of rotavirus in Kerala. DESIGN:Multicenter, cross-sectional study. SETTING:Eight representative hospitals in Kunnathunadu Thaluk, Ernakulam district,...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-014-0329-8
更新日期：2014-01-01 00:00:00
abstract：:In Kumbakonam, Tamil Nadu State in India, 384 final-year female students attending the Government College for Women completed a questionnaire so the researcher could assess their knowledge of prenatal and childhood immunizations, breast feeding, weaning, oral rehydration solution (ORS), and feeding during diarrhea. 5...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-012-0225-z
更新日期：2012-12-01 00:00:00
abstract：:We report a 71/2-year-boy with disseminated systemic cryptococcosis. Although other species have been incriminated, this appears to be the first report of Cryptococcus humicolus. The child was HIV negative. He was treated with amphotericin B and fluconazole with intensive supportive care. The child responded after 6 w...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-11-01 00:00:00
abstract：OBJECTIVE:Comparison of the clinical efficacy of a transparent, DPI (transparent Rotahaler) with MDI and spacers in childhood asthma. DESIGN:Open, randomized, crossover trial. SETTINGS:Out patient clinic of a referral pediatric center. METHODS:Thirty (mean 6.1 +/-2.7 years) children with moderate persistent asthma w...
journal_title：Indian pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2001-01-01 00:00:00
abstract：OBJECTIVE:To identify the factors influencing brain injury in infants with congenital heart disease (CHD) after cardiac surgery. METHODS:This retrospective study investigated 103 infants with CHD undergoing cardiac surgery between January 2013 and February 2016. Pre- and postoperative amplitude-integrated electroencep...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-02-15 00:00:00
abstract：:Five hundred ninety two children (6.0%) were diagnosed as persistent diarrhea (PD) out of a total attendance of 9795 cases in the Diarrhea Training and Treatment Unit (DTU) over a period of 1 year. Most of the cases were initially managed as outpatients on dietary advice and treatment of associated infections. Eighty ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the current spectrum of hepatobiliary disorders in children in Northern India. SETTING:Tertiary level referral hospital. METHODS:All children with hepatobiliary disorders presenting between January 1992 through July 1995 were evaluated by clinical assessment, liver function tests, viral and auto...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：:Jaundice as a presenting feature of pediatric acute myeloid leukemia is rare. We report two cases of AML who presented with obstructive jaundice, one with a malignant stricture at the common bile duct and other with a granulocytic sarcoma obstructing the bile duct. The prognosis is poor in these patients. ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2012-05-01 00:00:00
abstract：:The prevalence of Attention deficit hyperactivity disorder was estimated in 500 adolescents using Conners' parents and teachers rating scales. Thirty six (7.2%) adolescents had positive scores on both the scales. The parents and teachers also completed a Diagnostic and Statistical Manual-IV based questionnaire which s...
journal_title：Indian pediatrics
pub_type： 信件
doi：10.1007/s13312-014-0350-y
更新日期：2014-02-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-014-0531-8
更新日期：2014-11-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2003-04-01 00:00:00
abstract：:We observed a significant fall in neonatal mortality in babies weighing less than 2 kg during 1986 as compared to 1973 (7.94% vs 12.88%; p less than 0.005), and in preterm babies the mortality fell from 26.88 to 11.5% (p less than 0.001) during 1986. This was achieved despite 2-3 fold increase in the high risk babies ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:The discussion section explains the meaning of results to the readers, and addresses the implications of the findings emanating from the particular study. Authors should compare their results with previous reports, and attempt to explain similarities and differences. It is useful to outline the limitations and strengt...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0955-4
更新日期：2016-10-08 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s13312-013-0171-4
更新日期：2013-06-08 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2006-02-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2012-04-01 00:00:00
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journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-03-15 00:00:00
abstract：:This study was conducted to determine the frequency of antinuclear antibodies (ANA) positivity and uveitis in our newly diagnosed juvenile idiopathic arthritis (JIA) patients classified according to International League Against Rheumatology (ILAR) classification criteria. Ninety-two girls and 106 boys, totally 198 chi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-10-01 00:00:00
abstract：:There are well defined therapeutic protocols for childhood nephrotic syndrome. Appropriate therapy helps in minimizing side effects besides decreasing referrals to tertiary care centres. We have analysed the appropriateness of therapy of primary care physicians in 111 children with nephrotic syndrome referred to our I...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1994-02-01 00:00:00
abstract：: ...
journal_title：Indian pediatrics
pub_type： 评论,社论
doi：
更新日期：2018-11-15 00:00:00
abstract：:Berardinelli-Seip congenital lipodystrophy (BSCL) is a very rare genetic disorder characterized by lipoatrophy, hypertriglyceridemia, hepatomegaly and acromegaloid features. On the basis of mutational and haplotype analysis, BSCL families have been classified into three types BSCL 1, BSCL2 and BSCLX. We report Berardi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2006-05-01 00:00:00
abstract：:Highly active antiretroviral therapy is beyond reach of most HIV-infected children in developing countries. There is paucity of data on more affordable regimens such as ones based on nevirapine and 2 nucleoside reverse transcriptase inhibitors. We report our experience with the use of antiretroviral therapy in childre...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2005-08-01 00:00:00
