Abstract:
:Exercise activates neutrophil burst and this effect is dependent on training status and exercise intensity. In this study, the chronic effect of treadmill exercise on phagocytosis, production of reactive oxygen metabolites and expression of NADPH oxidase components in rat neutrophils was investigated. Neutrophils were obtained by intraperitoneal lavage with PBS. After 11 weeks of training the exercised group showed increased phagocytosis capacity (49%) and production of reactive oxygen metabolites (6.6-fold) when compared with neutrophils from the sedentary group. Exercised had no effect on expression of the membrane components of NADPH oxidase (p22( phox ), gp91( phox )). In contrast, there was an increase of the p47( phox ) mRNA levels (by 126%), the cytosolic component of the enzyme. In addition, exercise increased the protein content of p47( phox ) (by 22%) and of p67( phox ) (by 2.8-fold) in neutrophils. Evidence is then presented that training to moderate exercise increases phagocytosis and production of reactive oxygen metabolites and the expression of p47( phox ) and p67( phox ) in neutrophils. Therefore, moderate exercise might enable neutrophils to respond more efficiently when exposed to pathogens.
journal_name
Eur J Appl Physioljournal_title
European journal of applied physiologyauthors
Levada-Pires AC,Lambertucci RH,Mohamad M,Hirabara SM,Curi R,Pithon-Curi TCdoi
10.1007/s00421-007-0414-ysubject
Has Abstractpub_date
2007-05-01 00:00:00pages
153-60issue
2eissn
1439-6319issn
1439-6327journal_volume
100pub_type
杂志文章abstract:PURPOSE:Through time- and frequency-domain analysis, we compared the effects of acute hypobaric hypoxia on the changes in heart rate variability (HRV) following night sleeping and morning awakening in individuals with and without acute mountain sickness (AMS). METHOD:Thirty-nine nonacclimatised healthy individuals wer...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-017-3555-7
更新日期:2017-04-01 00:00:00
abstract::Duchenne muscular dystrophy (DMD) is caused by the absence of a functional dystrophin protein and is modeled by the mdx mouse. The mdx mouse suffers an early necrotic bout in the hind limb muscles lasting from approximately 4 to 7 weeks. The purpose of this investigation was to determine the extent to which dystrophin...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-011-1906-3
更新日期:2011-11-01 00:00:00
abstract:PURPOSE:There is contradictory evidence related to the impact of ultra-marathon running on right ventricular (RV) structure and function. Consequently, the aims of this study were to: (1) comprehensively assess RV structure and function before and immediately following a 100-mile ultra-marathon in highly trained runner...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-014-2995-6
更新日期:2015-01-01 00:00:00
abstract::Branched chain amino acids (BCAA), particularly leucine, have been suggested to be ergogenic for both endurance and strength/power performance. This study investigated the effects of dietary leucine supplementation on the exercise performance of outrigger canoeists. Thirteen (ten female, three male) competitive outrig...
journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00421-005-0036-1
更新日期:2006-08-01 00:00:00
abstract::Cardiopulmonary exercise test is the gold standard for the identification of the ventilatory compensation point (VCP), an important threshold for exercise training prescription. We hypothesized that changes in the slope of increment in minute ventilation (V'(E)) over heart rate (HR) during incremental exercise can be ...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-008-0777-8
更新日期:2008-09-01 00:00:00
abstract:PURPOSE:Passive muscle stiffness and muscle architecture at a given joint angle, as well as slack angle of the muscle have been shown to change after an acute bout of stretching. However, it remains unclear whether passive muscle stiffness at a given fascicle length is reduced after stretching. We aimed to elucidate th...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-017-3550-z
更新日期:2017-03-01 00:00:00
abstract:PURPOSE:Walking is a complex locomotor process that involves both spinal cord reflexes and cortical integration of peripheral nerve input. Maintaining an upright body position requires not only neuromuscular activity but also cardiovascular regulation. We postulated that plantar mechanical stimulation might modulate au...
journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00421-016-3479-7
更新日期:2016-12-01 00:00:00
abstract::In the past two decades oxygenation responses to incremental ramp exercise, measured non-invasively by means of near-infrared spectroscopy at different locations in the body, have advanced the insights on the underpinning mechanisms of the whole-body pulmonary oxygen uptake ([Formula: see text]) response. In healthy s...
journal_title:European journal of applied physiology
pub_type: 杂志文章,评审
doi:10.1007/s00421-016-3468-x
更新日期:2016-12-01 00:00:00
abstract::The purpose of this study was to determine whether cross-education, defined as the increase in strength of an untrained limb after training of the contralateral homologous limb, is specific to low and high velocity eccentric training. Twenty-six subjects were randomized into two groups ( n=13 each) that performed unil...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00421-003-0841-3
更新日期:2003-08-01 00:00:00
abstract:PURPOSE:Dietary nitrate (NO3 (-)) supplementation reduces the O2 cost of fixed-workload tasks performed in temperate environments but has not been examined in the heat. If this effect were retained it could reduce heatstroke risk in military personnel that are deployed for desert combat. METHODS:Nine men completed thr...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-015-3255-0
更新日期:2015-12-01 00:00:00
abstract::Free radical production and high catecholamine levels are implicated in the modulation of Na(+), K(+)-ATPase, and Mg(2+)-ATPase activities. The aim of this study was to investigate the effect of the mode of delivery on the above-mentioned enzyme activities in maternal-neonatal erythrocyte membrane. Women with normal p...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-008-0744-4
更新日期:2008-07-01 00:00:00
abstract::While intramuscular wire electrodes (IWE) for the measurement of neuromuscular function offer high spatial resolution for examining single motor unit activity, the resulting damage to muscle tissue and mechanical instability should be considered. We examined the influence of IWE type and component parts on muscle dama...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-006-0278-6
更新日期:2006-10-01 00:00:00
abstract::Musculoskeletal disorders in the neck and shoulder area are a major occupational concern in the European countries especially among elderly females. The aim was to assess these disorders based on quantitative EMG indicators and functional tests. 252 female computer users (45-68 years) were recruited from four European...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-005-0042-3
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:This study examined the effects of combined cooling and lower body heat maintenance during half-time on second-half intermittent sprint performances. METHODS:In a repeated measures design, nine males completed four intermittent cycling trials (32.1 ± 0.3 °C and 55.3 ± 3.7% relative humidity), with either one o...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-019-04177-8
更新日期:2019-08-01 00:00:00
abstract:PURPOSE:We analyzed the best performance times of master cycling athletes in the 200-3000 m track competitions to estimate the decay of maximal aerobic power (MAP) and anaerobic capacity (AnS) with aging. METHODS:In various decades of age (30-80 years), MAP and AnS were estimated using an iterative procedure as the va...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-016-3396-9
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:Sarcopenia can begin from the 4-5th decade of life and is exacerbated by obesity and inactivity. A combination of resistance exercise (RE) and endurance exercise is recommended to combat rising obesity and inactivity levels. However, work continues to elucidate whether interference in adaptive outcomes occur wh...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-017-3721-y
更新日期:2018-02-01 00:00:00
abstract::The purpose of this study was to examine the physiological effects of 3000-m swimming on subsequent 3-h cycling time trial performance in ultraendurance triathletes. Eight highly trained ultraendurance triathletes [mean (SEM) age 34 (2) years, body fat 12.5 (0.8)%, maximum oxygen consumption 63.2 (2.1) ml x kg(-1) x m...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s004210000229
更新日期:2000-09-01 00:00:00
abstract::Over the years, techniques for the study of human movement have ranged in complexity and precision from direct observation of the subject through activity diaries, questionnaires, and recordings of body movement, to the measurement of physiological responses, studies of metabolism and indirect and direct calorimetry. ...
journal_title:European journal of applied physiology
pub_type: 历史文章,杂志文章,评审
doi:10.1007/s00421-011-2268-6
更新日期:2012-08-01 00:00:00
abstract:PURPOSE:The aim is to provide better understanding of carbon dioxide (CO2) elimination during ventilation for both the healthy and atelectatic condition, derived in a pressure-controlled mode. Therefore, we present a theoretical analysis of CO2 elimination of healthy and diseased lungs. METHODS:Based on a single-compa...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-013-2754-0
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:The aim of this study was to investigate the effect of exhaustive exercise on technique preference and the accompanying physiological response during classic skiing at constant workload, but with varying incline-speed combinations. METHODS:Seven male competitive cross-country skiers performed four tests, each ...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-018-3965-1
更新日期:2018-11-01 00:00:00
abstract::The objective of this report was to analyse a potential role for FGF6 in muscle resistance to mechanical stress. Normal or regenerating muscles of FGF6 (-/-) mice versus wild-type mice were submitted to different protocols of damaging eccentric contractions (eccentric electrostimulation and intermittent downhill exerc...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-010-1784-0
更新日期:2011-07-01 00:00:00
abstract::Heart rate recovery (HRR) after submaximal exercise improves after training. However, it is unknown if this also occurs in already well-trained cyclists. Therefore, 14 well-trained cyclists (VO(2max) 60.3 +/- 7.2 ml kg(-1) min(-1); relative peak power output 5.2 +/- 0.6 W kg(-1)) participated in a high-intensity train...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-008-0952-y
更新日期:2009-03-01 00:00:00
abstract:: ...
journal_title:European journal of applied physiology
pub_type: 评论,信件
doi:10.1007/s00421-018-3990-0
更新日期:2018-12-01 00:00:00
abstract::Physiological hypertrophy in response to physical training is important in the differentiation of physiological and pathological left ventricular hypertrophy. The goal of our study was to define the structural characteristics of the heart in Chinese athletes. Between June 2005 and August 2005, 339 (165 male, 174 femal...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-007-0517-5
更新日期:2007-11-01 00:00:00
abstract::This study presents an original approach to the effect of regular sporting activity on the metabolism of lipids. We have examined the physiological variations of lipoparticles (Lp) AI, Lp B:CIII, Lp B:E, Lp (a) and the principal lipid markers in 21 high-level rugby players and men of the same age group who take part i...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-002-0613-5
更新日期:2002-11-01 00:00:00
abstract::The purpose of this article was to establish whether previously reported oxygen-to-mass ratios, used to predict flat and hill-climbing cycling performance, extend to similar power-to-mass ratios incorporating other, often quick and convenient measures of power output recorded in the laboratory [maximum aerobic power (...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-006-0189-6
更新日期:2006-07-01 00:00:00
abstract::This study was undertaken to elucidate the impact of long-term physical training on the modulation of stretch reflex excitability. To this end, electromyographic activities of the soleus muscle in response to quick toe-up rotation were compared between highly trained endurance runners (n = 8) and non-trained control s...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-012-2351-7
更新日期:2012-10-01 00:00:00
abstract::Randomized controlled trials (RCTs) on the topic of physical training and blood coagulation are rare and the effects are unclear. The aim of this study was to investigate whether endurance training adjusts blood coagulation and fibrinolysis at rest and after exercise. The study included 50 healthy untrained non-smoker...
journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00421-012-2564-9
更新日期:2013-06-01 00:00:00
abstract::The sleep-wake state has a profound influence on many, perhaps most, aspects of normal physiology and is strongly implicated in the mediation (or remediation) of impaired health and performance. Many sleep disorders stem from abnormal respiratory anatomy or sleep-induced changes in respiratory control, underscoring th...
journal_title:European journal of applied physiology
pub_type: 杂志文章,评审
doi:10.1007/s00421-002-0610-8
更新日期:2002-07-01 00:00:00
abstract::Whole-body vibration (WBV) leads to a rapid increase in intra-muscular temperature and enhances muscle power. The power-enhancing effects by WBV can, at least in part, be explained by intra-muscular temperature. However, this does not exclude possible neural effects of WBV occurring at the spinal level. The aim of thi...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-009-1215-2
更新日期:2010-01-01 00:00:00