Nongastric marginal zone B-cell lymphoma: analysis of 247 cases.

abstract：:In southeast Asia, the carrier frequency of two-gene alpha-thalassemia deletions is quite high, ranging from 4% to 14% depending on the population. The most common alpha-thalassemia-1 deletion is the so-called southeast Asian deletion (--(SEA)). In addition, a significant proportion of cases involve two other deletion...

journal_title：American journal of hematology

authors： Eng B,Patterson M,Borys S,Chui DH,Waye JS

更新日期：2000-01-01 00:00:00

abstract：:Prenatal diagnosis was carried out on a woman who had previously given birth to a son with a spontaneous mutation of C-->T transition at nt 31133 of the factor IX (F.IX) gene. The diagnosis was performed on chorionic villi sampling by the method of amplification-created restriction site (ACRS). It revealed a female fe...

journal_title：American journal of hematology

authors： Young JH,Wang JC,Gau JP,Hu HT

更新日期：1996-08-01 00:00:00

abstract：:The effect of heparin on platelet aggregation was systematically examined on platelets in plasma (PRP), as well as on gel-filtered, washed, and formaldehyde-fixed platelets. Results indicate that, although heparin causes a mild potentiation of platelet aggregation in the PRP systems, a significant inhibitory activity ...

journal_title：American journal of hematology

authors： Saba HI,Saba SR,Morelli GA

更新日期：1984-10-01 00:00:00

abstract：DISEASE OVERVIEW:Ring sideroblasts (RS) are erythroid precursors with abnormal perinuclear mitochondrial iron accumulation. Two myeloid neoplasms defined by the presence of RS, include refractory anemia with ring sideroblasts (RARS), now classified under myelodysplastic syndromes with RS (MDS-RS) and RARS with thromboc...

journal_title：American journal of hematology

authors： Patnaik MM,Tefferi A

更新日期：2017-03-01 00:00:00

abstract：:Essential thrombocythemia (ET) is a myeloproliferative disorder characterized by isolated overproduction of platelets, thrombohemorrhagic complications, and a median age of 50-60. When it occurs in younger patients, the incidence of complications has been reported to be quite low, with a good long-term prognosis. We r...

journal_title：American journal of hematology

authors： Millard FE,Hunter CS,Anderson M,Edelman MJ,Kosty MP,Luiken GA,Marino GG

更新日期：1990-01-01 00:00:00

abstract：:Using an in vitro system to evaluate the simultaneous use of two drugs, we previously have confirmed the synergism of vincristine and prednisolone cytotoxicity against lymphoid cells. Experiments were now carried out to determine whether other steroid hormones can be substituted for prednisolone. Partial or complete p...

journal_title：American journal of hematology

authors： Rosner F,Hirshaut Y,Grünwald HW,Deutsch S

更新日期：1978-01-01 00:00:00

abstract：:We have previously shown that humic acid (well-water humic acid, HA, and synthetic humic acid, SHA) enhances cell surface expression of tissue factor (TF). Here we report that incubation of human umbilical vein endothelial cells (HUVEC) for 2 hr with HA or SHA cause a rapid rise in TF mRNA levels, as shown by Northern...

journal_title：American journal of hematology

authors： Yang HL,Chiu HC,Lu FJ

更新日期：1996-03-01 00:00:00

abstract：:The presence of teardrop-shaped red cells in peripheral blood has traditionally been felt to reflect altered marrow architecture, namely myelofibrosis. We evaluated two patients with splenomegaly, moderately severe hemolytic anemia due to warm-reactive IgG anti-red cell autoantibody, and bone marrow erythroid hyperpla...

journal_title：American journal of hematology

authors： Farolino DL,Rustagi PK,Currie MS,Doeblin TD,Logue GL

更新日期：1986-04-01 00:00:00

abstract：:The value of menorrhagia as a predictor for mild bleeding disorders has been very little studied and the results are divergent. In the present study on 30 women with objectively verified menorrhagia, we found a significantly increased prevalence of von Willebrand's disease (20%). By keeping a strict sampling and labor...

journal_title：American journal of hematology

authors： Edlund M,Blombäck M,von Schoultz B,Andersson O

更新日期：1996-12-01 00:00:00

abstract：:A minority of super-utilizing adults with sickle cell disease (SCD) account for a disproportionate number of emergency department (ED) and hospital admissions. We performed a retrospective cohort study comparing the rate of admission before and after the opening of a clinic for adults with SCD. Unique to this clinic w...

journal_title：American journal of hematology

authors： Koch KL,Karafin MS,Simpson P,Field JJ

更新日期：2015-03-01 00:00:00

abstract：:Recent observations that the sickle RBC are excessively susceptible to phagocytosis by macrophages in vitro prompted me to look for evidence of in vivo erythrophagocytosis (Ep) in patients with sickle cell anemia (SS). Freshly prepared smears of unmanipulated blood of 27 patients with SS in steady state were examined ...

journal_title：American journal of hematology

authors： Solanki DL

更新日期：1985-12-01 00:00:00

abstract：:By using Dexter-type long-term marrow cultures (D-LTMC), it has been shown previously that hematopoietic progenitor cells (HPC) from patients with aplastic anemia (AA) have a deficient proliferation in vitro. The studies reported to date, however, have focused exclusively on granulomonocytic progenitors and no informa...

journal_title：American journal of hematology

authors： Gómez-Morales E,Martinez-Jaramillo G,Sánchez-Valle E,Valencia-Plata I,Arana-Trejo RM,Castro MA,Pizzuto-Chávez J,Mayani H

更新日期：1998-10-01 00:00:00

abstract：:Substantial evidence exists indicating T cell abnormalities in chronic lymphocytic leukemia (CLL). There is also evidence that the T cell is an important source of burst promoting activity (BPA) for the peripheral blood (PB) erythroid burst forming unit (BFU-e). We studied the BPA of T cells and response of BFU-e in n...

journal_title：American journal of hematology

authors： Socinski MA,Ershler WB

更新日期：1984-02-01 00:00:00

abstract：:This study was designed to explore the value of markers of bone turnover, macrophage inflammatory protein-1alpha (MIP-1alpha), and osteopontin (OPN) in the diagnosis of myeloma bone disease. Twenty-five patients with newly diagnosed and untreated multiple myeloma (MM), and 22 age-, sex-, and bone mineral density-match...

journal_title：American journal of hematology

authors： Dizdar O,Barista I,Kalyoncu U,Karadag O,Hascelik G,Cila A,Pinar A,Celik I,Kars A,Tekuzman G

更新日期：2007-03-01 00:00:00

abstract：:Fifteen recently diagnosed patients with acute leukemias admitted for induction chemotherapy were selected for study. When thrombocytopenic (venous platelet count less than 20 X 10(9)/l) these patients received prophylactic platelet transfusions. A total of 67 platelet transfusion therapies were administered and evalu...

journal_title：American journal of hematology

authors： Kutti J,Zaroulis CG,Safai-Kutti S,Dinsmore RE,Day NK,Good RA

更新日期：1981-11-01 00:00:00

abstract：:We report the clinical, molecular, and immunohistological findings of 20 Chinese patients with mantle cell lymphoma diagnosed over a 10-year period. The disease affected mainly elderly patients (median age, 65.5 years) with a male predominance (M/F, 3/1). Eighty percent presented with advanced stage III/IV disease but...

journal_title：American journal of hematology

authors： Chim CS,Chan AC,Choo CK,Kwong YL,Lie AK,Liang R

更新日期：1998-12-01 00:00:00

abstract：:Plerixafor, a recently approved peripheral blood progenitor cell mobilizing agent, is often added to granulocyte-colony stimulating factor (G-CSF) to mobilize peripheral blood progenitor cells in patients with lymphoma or myeloma who cannot mobilize enough CD34+ cells with G-CSF alone to undergo autologous stem cell t...

journal_title：American journal of hematology

authors： Smith VR,Popat U,Ciurea S,Nieto Y,Anderlini P,Rondon G,Alousi A,Qazilbash M,Kebriaei P,Khouri I,de Lima M,Champlin R,Hosing C

更新日期：2013-09-01 00:00:00

abstract：:The expression of a human erythroid cell surface antigen recognized by monoclonal antibody (mAB) HAE9 has been studied on peripheral blood reticulocytes by one- and two-color flow cytometry. Total reticulocyte count was determined using Thiazole Orange (TO) and flow cytometry. In normal individuals, 4.56% of reticuloc...

journal_title：American journal of hematology

authors： Mechetner EB,Sedmak DD,Barth RF

更新日期：1991-09-01 00:00:00

abstract：:We retrospectively measured various hemostatic markers in 240 patients with disseminated intravascular coagulation (DIC) before the onset of DIC and in 110 non-DIC patients, and examined their usefulness for the diagnosis of pre-DIC. Changes in prothrombin time ratio and fibrinogen levels were not significant before t...

journal_title：American journal of hematology

authors： Wada H,Sakuragawa N,Mori Y,Takagi M,Nakasaki T,Shimura M,Hiyoyama K,Nisikawa M,Gabazza EC,Deguchi K,Kazama M,Shiku H

更新日期：1999-04-01 00:00:00

abstract：:Acute lymphoblastic leukemia (ALL) with distinct fusion transcripts has unique clinical features. In this study, the incidence, clinical characteristics, early treatment response, and outcomes of 1,004 Chinese pediatric ALLs were analyzed. Patients with TEL-AML1 and E2A-PBX1 fusion genes or other B cell precursor ALLs...

journal_title：American journal of hematology

authors： Gao C,Zhao XX,Li WJ,Cui L,Zhao W,Liu SG,Yue ZX,Jiao Y,Wu MY,Li ZG

更新日期：2012-11-01 00:00:00

abstract：:We studied 15 patients with essential thrombocythemia (ET) before treatment and after normalization of platelet count by anagrelide. Significantly increased plasma levels of PDGF, TGFbeta, and bFGF were found. Patients with mild reticulin fibrosis in bone marrow had higher PDGF levels. During treatment, plasma TGFbeta...

journal_title：American journal of hematology

authors： Lev PR,Marta RF,Vassallu P,Molinas FC

更新日期：2002-06-01 00:00:00

abstract：:Limited data are available regarding optimal treatment with desmopressin (DDAVP) or intermediate-purity FVIII concentrates rich in VWF (CFCs) in patients with von Willebrand disease (VWD) who undergo planned surgery. We undertook a retrospective review over 10 years (1988-1997) and identified 27 patients treated with ...

journal_title：American journal of hematology

authors： Nitu-Whalley IC,Griffioen A,Harrington C,Lee CA

更新日期：2001-04-01 00:00:00

abstract：:We describe a 25-year-old black woman who presented with a long history of anemia requiring transfusions during childhood and adolescence. Molecular analysis revealed her to be a compound heterozygote for the sickle mutation and the approximately 22.7 kb deletion associated with hemoglobin Kenya. This patient's clinic...

journal_title：American journal of hematology

authors： Waye JS,Cai SP,Eng B,Chui DH,Francombe WH

更新日期：1992-12-01 00:00:00

abstract：:Arsenic trioxide (As(2)O(3)) has been found effective in the treatment in the treatment of acute promyelocytic leukemia (APML). Most studies with As(2)O(3) involve patients with APML who have relapsed following standard therapy. Between January 1998 and July 2000, 14 patients were recruited for an ongoing trial of As(...

journal_title：American journal of hematology

authors： Mathews V,Balasubramanian P,Shaji RV,George B,Chandy M,Srivastava A

更新日期：2002-08-01 00:00:00

abstract：:Chronic transfusion therapy is the treatment of choice for preventing stroke recurrence in children with sickle cell disease (SCD). The majority of children affected by this devastating complication live in the developing world where access to regular blood transfusions may be impractical. Since 2000, in the absence o...

journal_title：American journal of hematology

authors： Ali SB,Moosang M,King L,Knight-Madden J,Reid M

更新日期：2011-10-01 00:00:00

abstract：:Pure red cell aplasia (PRCA) sometimes accompanies thymoma. Herein, we report a PRCA patient with thymoma with a clonal disorder of T cells. A 55-year-old man presented with anemia and anterior mediastinum tumor. The laboratory study revealed hemoglobin 8.2 g/dl; leukocytes 15.8 x 10(9)/L with 76.5% neutrophils, 20.0%...

journal_title：American journal of hematology

authors： Masuda M,Arai Y,Okamura T,Mizoguchi H

更新日期：1997-04-01 00:00:00

abstract：:Thalidomide is being increasingly used in hematology and oncology. Its use is associated with neuropathy, sedation, edema, fatigue, constipation, and deep venous thrombosis. Cytopenias are unusual, but there are case reports. However, there are no reports of isolated thrombocytopenia. We describe here a case of prolon...

journal_title：American journal of hematology

authors： Prasad HK,Kaushal V,Mehta P

更新日期：2007-09-01 00:00:00

abstract：:The synthesis of alpha and non-alpha chains of human hemoglobin (Hb) was studied in reticulocytes and in BFUe-derived cell colonies from patients with alpha chain or beta chain deficiencies. The subjects included normal adults (alpha alpha/alpha alpha) with or without a beta chain variant (Hb S, Hb Leslie) or an alpha...

journal_title：American journal of hematology

authors： Huisman TH,Reese AL,Webber B,Okonjo K,Altay C,Felice AE

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of intravenous immunoglobulin (IVIG), in comparison with plasma exchange (PE), in the treatment of patients with thrombotic thrombocytopenic purpura/hemolytic-uremic syndrome (TTP/HUS). DESIGN:Prospective, nonrandomized comparative study. SETTING:Hematology department in a general hos...

journal_title：American journal of hematology

authors： Finazzi G,Bellavita P,Falanga A,Viero P,Barbui T

更新日期：1992-11-01 00:00:00

abstract：:Celecoxib, a specific cyclooxygenase-2 (Cox-2) inhibitor, has been shown to possess antitumor activity in a variety of cancer cells. However, the antitumor activity of celecoxib in hematopoietic tumors, especially in chronic myeloid leukemia (CML), has not been well established. This study was designed to investigate ...

journal_title：American journal of hematology

authors： Zhang GS,Liu DS,Dai CW,Li RJ

更新日期：2006-04-01 00:00:00