Abstract:
STUDY DESIGN:Randomized controlled animal study. OBJECTIVE:Test the effectiveness of a single-strip demineralized bone matrix with hyaluronan and gelatin. SUMMARY OF BACKGROUND DATA:Demineralized bone matrix is widely used to augment spinal fusion, however, the effect of changing the physical characteristic and carrier is not known. METHODS:Demineralized bone matrix was extracted from the bones of New Zealand White rabbits, and combined with hyaluronan and gelatin to form solid strips. Forty-eight rabbits were randomized into a control and 2 experimental groups. In the control group, fusion was attempted with autograft bone. For group 2, demineralized bone matrix strips alone and for group 3, autograft and demineralized bone matrix strips were used. The fusion was assessed with manual manipulation and radiographs. The volume of the fusion mass was determined from computed tomographic images. RESULTS:By the manual palpation test, the fusion rates were 37.5%, 93.8%, and 100%, for groups 1-3, respectively (P < 0.05). By radiography, the control group fusion rate was 68.7% compared with 100% for the experimental groups (P < 0.05). The mean bone volumes of the fusion mass were 2142.2 +/- 318.5, 3132.9 +/- 632.1, and 4181.6 +/- 609.5 mm3 for groups 1-3, respectively (P < 0.05). CONCLUSIONS:The demineralized bone matrix-gel strip was able to function as both a bone-graft enhancer and a bone graft substitute in rabbit posterolateral spine fusion.
journal_name
Spine (Phila Pa 1976)journal_title
Spineauthors
Choi Y,Oldenburg FP,Sage L,Johnstone B,Yoo JUdoi
10.1097/01.brs.0000250982.41666.55subject
Has Abstractpub_date
2007-01-01 00:00:00pages
36-41issue
1eissn
0362-2436issn
1528-1159pii
00007632-200701010-00007journal_volume
32pub_type
杂志文章相关文献
SPINE文献大全abstract:STUDY DESIGN:A retrospective study was undertaken which evaluated the medical records and imaging studies of a subset of patients managed by the spine service at Jackson Memorial Hospital who were diagnosed with an esophageal perforation in the setting of spinal surgery. OBJECTIVE:To assess the safety and efficacy of ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000182309.97403.ca
更新日期:2005-10-15 00:00:00
abstract:STUDY DESIGN:In this study, data are presented that provide the surgeon with additional information about the internal structure of the thoracic pedicle, which is especially useful for pedicle screw fixation in the thoracic spine. OBJECTIVES:To quantify the internal structure of the pedicle in the thoracic spine. SUM...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199602010-00002
更新日期:1996-02-01 00:00:00
abstract:STUDY DESIGN:A multicenter assessor-blinded randomized clinical trial was conducted. OBJECTIVES:To investigate the difference in effectiveness of manipulative therapy and interferential therapy for patients with acute low back pain when used as sole treatments and in combination. SUMMARY OF BACKGROUND DATA:Both manip...
journal_title:Spine
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1097/01.brs.0000142234.15437.da
更新日期:2004-10-15 00:00:00
abstract:STUDY DESIGN:Retrospective analysis of nationwide Veterans Health Administration clinical and administrative data. OBJECTIVE:Examine the association between HIV infection and the rate of spine surgery for degenerative spine disease. SUMMARY OF BACKGROUND DATA:Combination antiretroviral therapy has prolonged survival ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e318228f32d
更新日期:2012-04-01 00:00:00
abstract:STUDY DESIGN:Retrospective case series. OBJECTIVE:To report the effect of repeated growing rod (GR) lengthenings on the sagittal and pelvic profile in patients with early-onset scoliosis. SUMMARY OF BACKGROUND DATA:Posterior distraction-based GRs have gained popularity as a technique for the surgical management of ea...
journal_title:Spine
pub_type: 杂志文章,多中心研究
doi:10.1097/BRS.0000000000000565
更新日期:2014-10-15 00:00:00
abstract:STUDY DESIGN:The influence of lumbar disc height and cross-sectional area on the mechanical response of the disc to physiologic loading was determined using a finite element model. OBJECTIVES:To identify which geometric characteristics are potentially related to motion segment mechanical response to applied load, such...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199909150-00003
更新日期:1999-09-15 00:00:00
abstract:STUDY DESIGN:A 7-year-old ambulatory girl with complete bilateral agenesis of the ilium is reported. OBJECTIVE:To document the clinical evolution and the spino-pelvic balance of a girl with bilateral agenesis of the ilium. SUMMARY OF BACKGROUND DATA:Scapuloiliac dysostosis is a rare focal skeletal dysplasia consistin...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000169448.58989.a1
更新日期:2005-07-15 00:00:00
abstract::Pain is an extremely complex process that involves the interaction of an array of neurotransmitters and neuromodulators at all levels of the neuraxis. Identification of the receptors and processes that are involved in the transmission of pain at a spinal level has led to the use of new agents and new techniques in pai...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/00007632-199701010-00016
更新日期:1997-01-01 00:00:00
abstract:STUDY DESIGN:Systematic review and meta-analysis. OBJECTIVE:To compare the treatment effects of observational studies versus randomized controlled trials (RCTs) in cervical disc arthroplasty. SUMMARY OF BACKGROUND DATA:RCTs can be logistically challenging and sometimes insufficiently generalizable; well-designed obse...
journal_title:Spine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/BRS.0000000000001377
更新日期:2016-03-01 00:00:00
abstract:STUDY DESIGN:The pretension of the Dynesys cord was varied to evaluate its effects on both tissue responses and screw-spacer behaviors by the finite-element method. OBJECTIVE:This study aimed to provide detailed information about the motion-preserving and load-shielding mechanisms of the Dynesys screw-spacer joint. S...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e318290fb2e
更新日期:2013-06-01 00:00:00
abstract:STUDY DESIGN:We performed a retrospective review of 126 cases of infectious spondylodiscitis over a 4-year period. OBJECTIVE:Differentiation between pyogenic spondylodiscitis (PS) and tuberculous spondylodiscitis (TS) is essential for deciding on the appropriate therapeutic regimen. The aim of this study was to compar...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181e04dd3
更新日期:2010-10-01 00:00:00
abstract:STUDY DESIGN:This study developed and independently applied a spine tumor classification system, referred to as the Weinstein-Boriani-Biagini system, in a retrospective analysis of a series of patients with spinal giant cell tumors from three institutions. OBJECTIVE:To evaluate factors of potential prognostic signific...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199708010-00018
更新日期:1997-08-01 00:00:00
abstract:STUDY DESIGN:Retrospective analysis of prospectively collected multicenter series. OBJECTIVE:To evaluate the sagittal profile of surgically treated adolescent idiopathic scoliosis (AIS) patients. SUMMARY OF BACKGROUND DATA:With the increasing popularity of segmental pedicle screw spinal instrumentation, thoracic kyph...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181dccd63
更新日期:2010-06-15 00:00:00
abstract:STUDY DESIGN:Retrospective database review. OBJECTIVE:To determine the 90-day complication rate and 90-day and 1-year mortality in patients 80 years of age and older who were treated with posterolateral lumbar spinal fusion surgery and to compare these rates against those of elderly patients ages 65 to 79. SUMMARY OF...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000001759
更新日期:2017-03-15 00:00:00
abstract:STUDY DESIGN:Diagnosis, postoperative complications, and surgical results in patients over 70 years old who underwent surgery for lumbar nerve root compression of a degenerative origin were evaluated in a prospective, consecutive study. SUMMARY OF BACKGROUND DATA:Of the 50 patients investigated, 43 suffered from centr...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199407000-00001
更新日期:1994-07-01 00:00:00
abstract:STUDY DESIGN:Case report. OBJECTIVE:Presentation of the previously unreported technique of balloon kyphoplasty being used to prophylactically stabilize a vertebral body metastasis at risk of imminent fracture. SUMMARY OF BACKGROUND DATA:Many patients with spinal metastases are not suitable for a total en bloc resecti...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181a482f6
更新日期:2009-06-01 00:00:00
abstract::The detection of the posterior edge of the L4-L5 intervertebral disc has been accomplished by applying digital image processing techniques on conventional lateral radiograms of the spine, and the method is described. The results of this study have shown that there can be substantial absorption at the site of the disc ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198209000-00016
更新日期:1982-09-01 00:00:00
abstract:STUDY DESIGN:Observational and comparative study of the vertebral artery injury detected by 2-dimensional (2-D) time-of-flight magnetic resonance angiography (MRA) for admitting patients. Construct a strike-induced flexion injury model of cervical spine with blunt vertebral artery injury in dogs. OBJECTIVES:To evaluat...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000231722.86887.93
更新日期:2006-08-15 00:00:00
abstract::The major objective of this investigation was to study the effectiveness of the physical conditioning program used at the University of Miami Comprehensive Pain and Rehabilitation Center in restoring certain elements of the functional abilities of individuals suffering from chronic low-back pain and to evaluate the ef...
journal_title:Spine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007632-199203000-00012
更新日期:1992-03-01 00:00:00
abstract:STUDY DESIGN:A prospective follow-up study to detect the early neurological improvement after decompression surgery and to clarify its correlation with the late neurological outcome in patients with cervical compression myelopathy. OBJECTIVE:To reveal the suitability of a simple performance, 15-second grip-and-release...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e31824ac3d4
更新日期:2012-07-01 00:00:00
abstract::The purpose of this investigation was to examine the morphologic and histochemical characteristics of paraspinal muscles in patients with scoliosis after long-term electrical stimulation. Thirty-six children with idiopathic scoliosis, who had been treated with implantable muscle stimulators, had paraspinal muscle biop...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199207000-00007
更新日期:1992-07-01 00:00:00
abstract:STUDY DESIGN:Prospective randomized study to compare the efficacy of facet joint injection with lidocaine and facet joint injection with saline in two groups of patients with low back pain, with and without clinical criteria that were determined in a previous study to implicate the facet joint as the primary source of ...
journal_title:Spine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007632-199809150-00011
更新日期:1998-09-15 00:00:00
abstract:STUDY DESIGN:Retrospective clinical study of a prospective database. OBJECTIVE:This study aims to determine whether revision spinal fusion surgery is worthwhile in patients older than 75 from a risk-benefit perspective. SUMMARY OF BACKGROUND DATA:The benefits of spinal fusion in patients older than 65 is well documen...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000000067
更新日期:2014-01-01 00:00:00
abstract:STUDY DESIGN:Retrospective review of a prospective multicenter database evaluating surgical adult spinal deformity (ASD) patients. OBJECTIVE:This study aims to identify risk factors for medical complications in ASD patients undergoing surgery. SUMMARY OF BACKGROUND DATA:ASD surgery is known for its high complication ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000001636
更新日期:2016-11-15 00:00:00
abstract:STUDY DESIGN:A correlation was studied between degenerative spondylolisthesis (DSL) of the cervical spine and spinal-evoked potentials intraoperatively recorded in elderly patients who had surgical treatment for cervical spondylotic myelopathy. OBJECTIVE:To investigate the functional importance of cervical DSL in elde...
journal_title:Spine
pub_type: 临床试验,杂志文章
doi:10.1097/01.BRS.0000067263.73474.97
更新日期:2003-06-01 00:00:00
abstract::Spinal cord injury continues to be a major cause of morbidity, particularly among young people involved in vehicle-related trauma, falls, and sports injuries. Although research advances are still a long way from clinical treatments, recent studies on animals have indicated new possibilities for recovery of function. I...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/00007632-199905010-00019
更新日期:1999-05-01 00:00:00
abstract:STUDY DESIGN:A prospective clinical study in which autologous rib graft, harvested during the thoracotomy in staged scoliosis correction, is stored within the patient for use during the second stage (posterior intrumentation and fusion). OBJECTIVE:To determine whether the bone stored by this technique is biologically ...
journal_title:Spine
pub_type: 临床试验,杂志文章
doi:10.1097/00007632-199808150-00013
更新日期:1998-08-15 00:00:00
abstract:STUDY DESIGN:Systematic literature review and expert survey OBJECTIVE.: The aim of this study was to determine factors associated with neurologic improvement in patients with neurologic deficits secondary to metastatic epidural spinal cord compression (MESCC). Clear understanding of these factors will guide surgical de...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/BRS.0000000000001827
更新日期:2016-10-15 00:00:00
abstract:STUDY DESIGN:Retrospective cohort study. OBJECTIVE:This study aimed to identify the rates and causes of unplanned hospital readmission at 30 days and 1 year after surgical treatment of primary and metastatic spinal tumors. SUMMARY OF BACKGROUND DATA:Primary spine tumors and non-spine tumors metastatic to the spine ca...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000000517
更新日期:2014-10-01 00:00:00
abstract:STUDY DESIGN:A prospective study was conducted in patients who underwent surgeries for sciatica. The results were compared to those of control subjects. OBJECTIVES:This study expanded knowledge about the pathogenesis of back pain and sciatica in disc herniation. METHODS:Nucleus pulposus, retrieved from 10 patients wh...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199406000-00003
更新日期:1994-06-15 00:00:00