Abstract:
:Expression of Bacillus thuringiensis delta-endotoxins has proven to be a successful strategy for obtaining insect resistance in transgenic plants. Drawbacks of expression of a single resistance gene are the limited target spectrum and the potential for rapid adaptation of the pest. Hybrid toxins with a wider target spectrum in combination with existing toxins may be used as tool to mitigate these problems. In this study, Desiree potato plants were genetically modified to resist attack by insect species belonging to the orders Coleoptera and Lepidoptera, through the insertion of such a hybrid gene, SN19. Transgenic plants were shown to be resistant against Colorado potato beetle larvae and adults, potato tuber moth larvae, and European corn borer larvae. These are the first transgenic plants resistant to pests belonging to two different insect orders. In addition, the target receptor recognition of this hybrid protein is expected to be different from Cry proteins currently in use for these pests. This makes it a useful tool for resistance management strategies.
journal_name
Plant Biotechnol Jjournal_title
Plant biotechnology journalauthors
Naimov S,Dukiandjiev S,de Maagd RAdoi
10.1046/j.1467-7652.2003.00005.xsubject
Has Abstractpub_date
2003-01-01 00:00:00pages
51-7issue
1eissn
1467-7644issn
1467-7652pii
PBI005journal_volume
1pub_type
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